The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging

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Publisher : John Wiley & Sons
ISBN 13 : 1118503678
Total Pages : 514 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging by : Andre S. Merbach

Download or read book The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging written by Andre S. Merbach and published by John Wiley & Sons. This book was released on 2013-02-19 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Resonance Imaging (MRI) is one of the most important tools in clinical diagnostics and biomedical research. The number of MRI scanners operating around the world is estimated to be approximately 20,000, and the development of contrast agents, currently used in about a third of the 50 million clinical MRI examinations performed every year, has largely contributed to this significant achievement. This completely revised and extended second edition: Includes new chapters on targeted, responsive, PARACEST and nanoparticle MRI contrast agents. Covers the basic chemistries, MR physics and the most important techniques used by chemists in the characterization of MRI agents from every angle from synthesis to safety considerations. Is written for all of those involved in the development and application of contrast agents in MRI. Presented in colour, it provides readers with true representation and easy interpretation of the images. A word from the Authors: Twelve years after the first edition published, we are convinced that the chemistry of MRI agents has a bright future. By assembling all important information on the design principles and functioning of magnetic resonance imaging probes, this book intends to be a useful tool for both experts and newcomers in the field. We hope that it helps inspire further work in order to create more efficient and specific imaging probes that will allow materializing the dream of seeing even deeper and better inside the living organisms. Reviews of the First Edition: "...attempts, for the first time, to review the whole spectrum of involved chemical disciplines in this technique..."—Journal of the American Chemical Society "...well balanced in its scope and attention to detail...a valuable addition to the library of MR scientists..."—NMR in Biomedicine

The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119991765
Total Pages : 514 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging by : Andre S. Merbach

Download or read book The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging written by Andre S. Merbach and published by John Wiley & Sons. This book was released on 2013-04-15 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Resonance Imaging (MRI) is one of the most important tools in clinical diagnostics and biomedical research. The number of MRI scanners operating around the world is estimated to be approximately 20,000, and the development of contrast agents, currently used in about a third of the 50 million clinical MRI examinations performed every year, has largely contributed to this significant achievement. This completely revised and extended second edition: Includes new chapters on targeted, responsive, PARACEST and nanoparticle MRI contrast agents. Covers the basic chemistries, MR physics and the most important techniques used by chemists in the characterization of MRI agents from every angle from synthesis to safety considerations. Is written for all of those involved in the development and application of contrast agents in MRI. Presented in colour, it provides readers with true representation and easy interpretation of the images. A word from the Authors: Twelve years after the first edition published, we are convinced that the chemistry of MRI agents has a bright future. By assembling all important information on the design principles and functioning of magnetic resonance imaging probes, this book intends to be a useful tool for both experts and newcomers in the field. We hope that it helps inspire further work in order to create more efficient and specific imaging probes that will allow materializing the dream of seeing even deeper and better inside the living organisms. Reviews of the First Edition: "...attempts, for the first time, to review the whole spectrum of involved chemical disciplines in this technique..."—Journal of the American Chemical Society "...well balanced in its scope and attention to detail...a valuable addition to the library of MR scientists..."—NMR in Biomedicine

The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging

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Author :
Publisher : Wiley
ISBN 13 : 9780471607786
Total Pages : 0 pages
Book Rating : 4.6/5 (77 download)

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Book Synopsis The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging by : André E. Merbach

Download or read book The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging written by André E. Merbach and published by Wiley. This book was released on 2001-04-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been a huge increase in the use of MRI and contrast agents in medicine in recent years as evidenced by a big increase in the number of hospitals with MRI machines and the ever-increasing number of examinations using contrast agents. Contrast agents have revolutionized the use of Magnetic Resonance Imaging (MRI) in medical diagnostics, allowing doctors to distinguish between normal and abnormal tissues and ultimately improving prognosis for the patient. This monograph covers all aspects of production, use, operating mechanisms and theory of these diagnostic agents, used to produce high contrast images in MRI. It will therefore be unique resource for what is currently a very active domain of research both in universities and in industry. The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging is a comprehensive treatise: * written by the most active scientists in the field of contrast agents for medical MRI - from both university and industrial backgrounds * covering the topic from every angle from synthesis to safety considerations * invaluable to physicists, chemists, biologists as well as physicians * the first in-depth coverage of this topic

Medical Imaging Contrast Agents: A Clinical Manual

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Author :
Publisher : Springer Nature
ISBN 13 : 3030792560
Total Pages : 303 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Medical Imaging Contrast Agents: A Clinical Manual by : Sukru Mehmet Erturk

Download or read book Medical Imaging Contrast Agents: A Clinical Manual written by Sukru Mehmet Erturk and published by Springer Nature. This book was released on 2021-08-24 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume highlights and broadens our understanding of the correct use and the possible contraindications of contrast agents applied in radiology. Written by experts in the field, it not only focuses on the chemistry, physiochemical properties and pharmacokinetics of both iodinated and gadolinium-containing contrast agents, but also on the relevant safety issues such as frequency of their short- and long-term side effects and ways to avoid them nephrotoxicity risk related to the iodinated contrast agents NSF (nephrogenic systemic fibrosis) accumulation of gadolinium in the brain use of contrast agents in pediatric patients and pregnancy It also includes essential data on the use of contrast agents, such as scanning protocols, in the context of various clinical conditions. This comprehensive manual addresses all professionals involved in radiological imaging and is an invaluable tool for radiologists and technologists, as well as for residents and clinicians.

Electron Paramagnetic Resonance Spectroscopy

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Publisher : Springer Nature
ISBN 13 : 3030396630
Total Pages : 420 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Electron Paramagnetic Resonance Spectroscopy by : Patrick Bertrand

Download or read book Electron Paramagnetic Resonance Spectroscopy written by Patrick Bertrand and published by Springer Nature. This book was released on 2020-02-03 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although originally invented and employed by physicists, electron paramagnetic resonance (EPR) spectroscopy has proven to be a very efficient technique for studying a wide range of phenomena in many fields, such as chemistry, biochemistry, geology, archaeology, medicine, biotechnology, and environmental sciences. Acknowledging that not all studies require the same level of understanding of this technique, this book thus provides a practical treatise clearly oriented toward applications, which should be useful to students and researchers of various levels and disciplines. In this book, the principles of continuous wave EPR spectroscopy are progressively, but rigorously, introduced, with emphasis on interpretation of the collected spectra. Each chapter is followed by a section highlighting important points for applications, together with exercises solved at the end of the book. A glossary defines the main terms used in the book, and particular topics, whose knowledge is not required for understanding the main text, are developed in appendices for more inquisitive readers.

Contrast Agents I

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Author :
Publisher : Springer
ISBN 13 : 354045733X
Total Pages : 249 pages
Book Rating : 4.5/5 (44 download)

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Book Synopsis Contrast Agents I by : Werner Krause

Download or read book Contrast Agents I written by Werner Krause and published by Springer. This book was released on 2003-07-01 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extracellular MRI and X-ray contrast agents are characterized by their phar- cokinetic behaviour.After intravascular injection their plasma-level time curve is characeterized by two phases. The agents are rapidly distributed between plasma and interstitial spaces followed by renal elimination with a terminal half-live of approximatly 1–2 hours. They are excreted via the kidneys in unchanged form by glomerular filtration. Extracellular water-soluble contrast agents to be applied for X-ray imaging were introduced into clinical practice in 1923. Since that time they have proved to be most valuable tools in diagnostics.They contain iodine as the element of choice with a sufficiently high atomic weight difference to organic tissue. As positive contrast agents their attenuation of radiation is higher compared with the attenuation of the surrounding tissue. By this contrast enhancement X-ray diagnostics could be improved dramatically. In 2,4,6-triiodobenzoic acid derivatives iodine is firmly bound. Nowadays diamides of the 2,4,6-triiodo-5-acylamino-isophthalic acid like iopromide (Ultravist, Fig. 1) are used as non-ionic (neutral) X-ray contrast agents in most cases [1].

Contrast Agents in Magnetic Resonance Imaging

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Publisher :
ISBN 13 : 9781904536413
Total Pages : 506 pages
Book Rating : 4.5/5 (364 download)

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Book Synopsis Contrast Agents in Magnetic Resonance Imaging by : Reza Arshady

Download or read book Contrast Agents in Magnetic Resonance Imaging written by Reza Arshady and published by . This book was released on 2009-09 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive treatise on the chemistry, physics and imaging applications of practically all types of contrast agents used in magnetic resonance imaging (MRI).

MRI Contrast Agents

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Publisher : Springer
ISBN 13 : 9811025290
Total Pages : 125 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis MRI Contrast Agents by : Sophie Laurent

Download or read book MRI Contrast Agents written by Sophie Laurent and published by Springer. This book was released on 2016-11-03 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the multiple aspects of (i) preparation of the magnetic core, (ii) the stabilization with different coatings, (iii) the physico-chemical characterization and (iv) the vectorization to obtain specific nanosystems. Several bio-applications are also presented in this book. In the early days of Magnetic Resonance Imaging (MRI), paramagnetic ions were proposed as contrast agents to enhance the diagnostic quality of MR images. Since then, academic and industrial efforts have been devoted to the development of new and more efficient molecular, supramolecular and nanoparticular systems. Old concepts and theories, like paramagnetic relaxation, were revisited and exploited, leading to new scientific tracks. With their high relaxivity payload, the superparamagnetic nanoparticles are very appealing in the context of molecular imaging but challenges are still numerous: absence of toxicity, specificity, ability to cross the biological barriers, etc.

Contrast Agents for MRI

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Publisher : Royal Society of Chemistry
ISBN 13 : 1788012542
Total Pages : 612 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Contrast Agents for MRI by : Valérie C Pierre

Download or read book Contrast Agents for MRI written by Valérie C Pierre and published by Royal Society of Chemistry. This book was released on 2017-11-09 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a practical reference guide for designing and performing experiments, this book focuses on the five most common classes of contrast agents for MRI namely gadolinium complexes, chemical exchange saturation transfer agents, iron oxide nanoparticles, manganese complexes and fluorine contrast agents. It describes how to characterize and evaluate them and for each class, a description of the theory behind their mechanisms is discussed briefly to orient the new reader. Detailed subchapters discuss the different physical chemistry methods used to characterize them in terms of their efficacy, safety and in vivo behavior. Important consideration is also given to the different physical properties that affect the performance of the contrast agents. The editors and contributors are at the forefront of research in the field of MRI contrast agents and this unique, cutting edge book is a timely addition to the literature in this area.

Gadolinium

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Publisher :
ISBN 13 : 9781616689919
Total Pages : 0 pages
Book Rating : 4.6/5 (899 download)

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Book Synopsis Gadolinium by : Caden C. Thompson

Download or read book Gadolinium written by Caden C. Thompson and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gadolinium is a silvery-white, malleable and ductile rare-earth metal. It has exceptionally high absorption of neutrons and therefore is used for shielding in neutron radiography and in nuclear reactors. Because of its paramagnetic properties, solutions of organic gadolinium complexes and gadolinium compounds are the most popular intravenous MRI contrast agents in medical magnetic resonance imaging. This book presents and discusses research on the application of gadolinium-based contrast agents in abdominal MRIs; a review of GBC agents as causes of acute kidney injury and triggers of nephrogenic systemic fibrosis and others.

Fluorine Magnetic Resonance Imaging

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Publisher : CRC Press
ISBN 13 : 9814745324
Total Pages : 462 pages
Book Rating : 4.8/5 (147 download)

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Book Synopsis Fluorine Magnetic Resonance Imaging by : Ulrich Flogel

Download or read book Fluorine Magnetic Resonance Imaging written by Ulrich Flogel and published by CRC Press. This book was released on 2016-10-26 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, fluorine (19F) magnetic resonance imaging (MRI) has garnered significant scientific interest in the biomedical research community owing to the unique properties of fluorinated materials and the 19F nucleus. Fluorine has an intrinsically sensitive nucleus for MRI. There is negligible endogenous 19F in the body and thus there is no background signal. Fluorine-containing compounds are ideal tracer labels for a wide variety of MRI applications. Moreover, the chemical shift and nuclear relaxation rate can be made responsive to physiology via creative molecular design. This book is an interdisciplinary compendium that details cutting-edge science and medical research in the emerging field of 19F MRI. Edited by Ulrich Flögel and Eric Ahrens, two prominent MRI researchers, this book will appeal to investigators involved in MRI, biomedicine, immunology, pharmacology, probe chemistry, and imaging physics.

Biomedical Imaging

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Publisher : Royal Society of Chemistry
ISBN 13 : 1849732914
Total Pages : 552 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Biomedical Imaging by : Martin Braddock

Download or read book Biomedical Imaging written by Martin Braddock and published by Royal Society of Chemistry. This book was released on 2011-11-23 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: The focus of this new book is for medicinal chemists on the chemical agents that have been used, or might be required in the future, and the methods of synthesis for inserting the reporter groups. Medicinal chemists need to know the critical issues involved in using such chemical agents with regard to the biological applications - for instance - what properties are needed chemically and why? The topics covered in the book are: PET, SPECT, contrast agents, radioimaging/radionuclide conjugates, receptor mapping, small animal imaging (eg. WBAR - whole body autoradiography); photoinduced labelling, as well as chapters on the physical techniques used including: NMR, mass spectrometry and Xray. A key reference for academics, postgraduates, researchers, industrialists and professionals working in or joining this field.

Visualizing Chemistry

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Publisher : National Academies Press
ISBN 13 : 030916463X
Total Pages : 222 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Visualizing Chemistry by : National Research Council

Download or read book Visualizing Chemistry written by National Research Council and published by National Academies Press. This book was released on 2006-06-01 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists and engineers have long relied on the power of imaging techniques to help see objects invisible to the naked eye, and thus, to advance scientific knowledge. These experts are constantly pushing the limits of technology in pursuit of chemical imagingâ€"the ability to visualize molecular structures and chemical composition in time and space as actual events unfoldâ€"from the smallest dimension of a biological system to the widest expanse of a distant galaxy. Chemical imaging has a variety of applications for almost every facet of our daily lives, ranging from medical diagnosis and treatment to the study and design of material properties in new products. In addition to highlighting advances in chemical imaging that could have the greatest impact on critical problems in science and technology, Visualizing Chemistry reviews the current state of chemical imaging technology, identifies promising future developments and their applications, and suggests a research and educational agenda to enable breakthrough improvements.

Field-cycling NMR Relaxometry

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Publisher : Royal Society of Chemistry
ISBN 13 : 1788015509
Total Pages : 590 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Field-cycling NMR Relaxometry by : Rainer Kimmich

Download or read book Field-cycling NMR Relaxometry written by Rainer Kimmich and published by Royal Society of Chemistry. This book was released on 2018-10-11 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: Field-cycling NMR relaxometry is evolving into a methodology of widespread interest with recent technological developments resulting in powerful and versatile commercial instruments. Polymers, liquid crystals, biomaterials, porous media, tissue, cement and many other materials of practical importance can be studied using this technique. This book summarises the expertise of leading scientists in the area and the editor is well placed, after four decades of working in this field, to ensure a broad ranging and high quality title. Starting with an overview of the basic principles of the technique and the scope of its use, the content then develops to look at theory, instrumentation, practical limitations and applications in different systems. Newcomers to the field will find this book invaluable for successful use of the technique. Researchers already in academic and industrial settings, interested in molecular dynamics and magnetic resonance, will discover an important addition to the literature.

Cardiovascular Magnetic Resonance Imaging

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Publisher : Springer
ISBN 13 : 1493988417
Total Pages : 473 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Cardiovascular Magnetic Resonance Imaging by : Raymond Y. Kwong

Download or read book Cardiovascular Magnetic Resonance Imaging written by Raymond Y. Kwong and published by Springer. This book was released on 2019-01-31 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: The significantly updated second edition of this important work provides an up-to-date and comprehensive overview of cardiovascular magnetic resonance imaging (CMR), a rapidly evolving tool for diagnosis and intervention of cardiovascular disease. New and updated chapters focus on recent applications of CMR such as electrophysiological ablative treatment of arrhythmias, targeted molecular MRI, and T1 mapping methods. The book presents a state-of-the-art compilation of expert contributions to the field, each examining normal and pathologic anatomy of the cardiovascular system as assessed by magnetic resonance imaging. Functional techniques such as myocardial perfusion imaging and assessment of flow velocity are emphasized, along with the exciting areas of artherosclerosis plaque imaging and targeted MRI. This cutting-edge volume represents a multi-disciplinary approach to the field, with contributions from experts in cardiology, radiology, physics, engineering, physiology and biochemistry, and offers new directions in noninvasive imaging. The Second Edition of Cardiovascular Magnetic Resonance Imaging is an essential resource for cardiologists and radiologists striving to lead the way into the future of this important field.

MRI

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Publisher : John Wiley & Sons
ISBN 13 : 1119013038
Total Pages : 248 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis MRI by : Brian M. Dale

Download or read book MRI written by Brian M. Dale and published by John Wiley & Sons. This book was released on 2015-08-06 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fifth edition of the most accessible introduction to MRI principles and applications from renowned teachers in the field provides an understandable yet comprehensive update. Accessible introductory guide from renowned teachers in the field Provides a concise yet thorough introduction for MRI focusing on fundamental physics, pulse sequences, and clinical applications without presenting advanced math Takes a practical approach, including up-to-date protocols, and supports technical concepts with thorough explanations and illustrations Highlights sections that are directly relevant to radiology board exams Presents new information on the latest scan techniques and applications including 3 Tesla whole body scanners, safety issues, and the nephrotoxic effects of gadolinium-based contrast media

Magnetic Resonance Imaging

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Publisher : John Wiley & Sons
ISBN 13 : 0471720852
Total Pages : 976 pages
Book Rating : 4.4/5 (717 download)

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Book Synopsis Magnetic Resonance Imaging by : Robert W. Brown

Download or read book Magnetic Resonance Imaging written by Robert W. Brown and published by John Wiley & Sons. This book was released on 2014-06-23 with total page 976 pages. Available in PDF, EPUB and Kindle. Book excerpt: New edition explores contemporary MRI principles and practices Thoroughly revised, updated and expanded, the second edition of Magnetic Resonance Imaging: Physical Principles and Sequence Design remains the preeminent text in its field. Using consistent nomenclature and mathematical notations throughout all the chapters, this new edition carefully explains the physical principles of magnetic resonance imaging design and implementation. In addition, detailed figures and MR images enable readers to better grasp core concepts, methods, and applications. Magnetic Resonance Imaging, Second Edition begins with an introduction to fundamental principles, with coverage of magnetization, relaxation, quantum mechanics, signal detection and acquisition, Fourier imaging, image reconstruction, contrast, signal, and noise. The second part of the text explores MRI methods and applications, including fast imaging, water-fat separation, steady state gradient echo imaging, echo planar imaging, diffusion-weighted imaging, and induced magnetism. Lastly, the text discusses important hardware issues and parallel imaging. Readers familiar with the first edition will find much new material, including: New chapter dedicated to parallel imaging New sections examining off-resonance excitation principles, contrast optimization in fast steady-state incoherent imaging, and efficient lower-dimension analogues for discrete Fourier transforms in echo planar imaging applications Enhanced sections pertaining to Fourier transforms, filter effects on image resolution, and Bloch equation solutions when both rf pulse and slice select gradient fields are present Valuable improvements throughout with respect to equations, formulas, and text New and updated problems to test further the readers' grasp of core concepts Three appendices at the end of the text offer review material for basic electromagnetism and statistics as well as a list of acquisition parameters for the images in the book. Acclaimed by both students and instructors, the second edition of Magnetic Resonance Imaging offers the most comprehensive and approachable introduction to the physics and the applications of magnetic resonance imaging.