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Author : Penny R. Drago
Publisher :
ISBN 13 :
Total Pages : 748 pages
Book Rating : 4.:/5 (225 download)
Download or read book The Chemistry and Anticancer Activity of Organoplatinum(II)/(IV) Complexes written by Penny R. Drago and published by . This book was released on 2004 with total page 748 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Sun Hongmao
Publisher : Woodhead Publishing
ISBN 13 : 0081001053
Total Pages : 293 pages
Book Rating : 4.0/5 (81 download)
Download or read book A Practical Guide to Rational Drug Design written by Sun Hongmao and published by Woodhead Publishing. This book was released on 2015-10-05 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is not going to be an exhaustive survey covering all aspects of rational drug design. Instead, it is going to provide critical know-how through real-world examples. Relevant case studies will be presented and analyzed to illustrate the following: how to optimize a lead compound whether one has high or low levels of structural information; how to derive hits from competitors’ active compounds or from natural ligands of the targets; how to springboard from competitors’ SAR knowledge in lead optimization; how to design a ligand to interfere with protein-protein interactions by correctly examining the PPI interface; how to circumvent IP blockage using data mining; how to construct and fully utilize a knowledge-based molecular descriptor system; how to build a reliable QSAR model by focusing on data quality and proper selection of molecular descriptors and statistical approaches. A Practical Guide to Rational Drug Design focuses on computational drug design, with only basic coverage of biology and chemistry issues, such as assay design, target validation and synthetic routes. Discusses various tactics applicable to daily drug design Readers can download the materials used in the book, including structures, scripts, raw data, protocols, and codes, making this book suitable resource for short courses or workshops Offers a unique viewpoint on drug discovery research due to the author’s cross-discipline education background Explores the author’s rich experiences in both pharmaceutical and academic settings
Author :
Publisher : Academic Press
ISBN 13 : 0128054344
Total Pages : 686 pages
Book Rating : 4.1/5 (28 download)
Download or read book Peptide, Protein and Enzyme Design written by and published by Academic Press. This book was released on 2016-08-27 with total page 686 pages. Available in PDF, EPUB and Kindle. Book excerpt: De Novo Enzyme Design, the newest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume includes the design of metal binding maquettes, insertion of non-natural cofactors, Cu metallopeptides, non-covalent interactions in peptide assemblies, peptide binding and bundling, heteronuclear metalloenzymes, florinated peptides, De Novo imaging agents, and protein-protein interaction. Continues the legacy of this premier serial with quality chapters on de novo enzyme design Represents the newest volume in the Methods in Enzymology series, providing premier, quality chapters authored by leaders in the field Ideal reference for those interested in the study of enzyme design that looks at both structure and mechanism
Author : Klaus Gubernator
Publisher : Wiley-VCH
ISBN 13 :
Total Pages : 176 pages
Book Rating : 4.3/5 (91 download)
Download or read book Structure-based Ligand Design, Volume 6 written by Klaus Gubernator and published by Wiley-VCH. This book was released on 1998-09 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Most drugs bind to a clearly defined macromolecular target that is complementary in terms of structure and chemistry. This observation is the basic paradigm of structure-based ligand design... highlights real-life applications such as the discovery of HIV-protease inhibitors... this volume is an indispensable tool for every scientist working in drug discovery".
Author : N. Anand
Publisher : Elsevier
ISBN 13 : 0080527523
Total Pages : 525 pages
Book Rating : 4.0/5 (85 download)
Download or read book Approaches to Design and Synthesis of Antiparasitic Drugs written by N. Anand and published by Elsevier. This book was released on 1997-07-10 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a comprehensive and up to date account of the chemotherapy of parasitic diseases, both human and veterinary. The book starts with an overview of parasitic diseases. The body of the book is divided into two parts: antihelminthic drugs, and antiprotozoal drugs. Both parts start with chapters highlighting the 'biochemical targets' available for chemotherapeutic interference. Individual chapters deal with one chemical class of compounds and describe their origin, structure-activity relationship, mode of action, and methods of synthesis and their status both in clinical and veterinary practice. The book will be useful to a wide spectrum of readers: students embarking on a research career in parasitic chemotherapy, clinicians (and veterinarians) and clinical pharmacologists desiring detailed information about the drugs currently in use, and pharmaceutical technologists wanting to update their knowledge of the methods of manufacture.
Author : Ronald I. Shorr
Publisher : Saunders
ISBN 13 : 9781416002086
Total Pages : 0 pages
Book Rating : 4.0/5 (2 download)
Download or read book Drugs for the Geriatric Patient written by Ronald I. Shorr and published by Saunders. This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This user-friendly, comprehensive drug reference - available in print and electronically for handheld, point-of-care usage -provides clinical information on more than 1000 drugs and their use in geriatric patients. In addition to dosage information and clinical indications, this reference also addresses the challenging issues of drug-drug and drug-disease interactions, polypharmacy, toxicity, compromised renal and hepatic function, withdrawal events, and more. Useful summary sections provide 1at a glance' conclusions, recommendations and clinical pearls. Quarterly updates to the handheld version ensure up-to-date access to the latest drug information and indications in the geriatric patient. Get comprehensive guidance on all the drugs you could conceivably encounter in treating the geriatric patient. Better serve your geriatric patients with dosage and usage guidelines developed specifically for them. Stay on top of all the latest drug information, including dosage updates and new drugs being released with frequent updates to the PDA version. Find information quickly using the practical, clinically-focused, full-color format.
Author : Howard Frederick Johnson
Publisher :
ISBN 13 :
Total Pages : 174 pages
Book Rating : 4.0/5 (17 download)
Download or read book The Treatment of Incurable Diseases written by Howard Frederick Johnson and published by . This book was released on 1851 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ananda Shiva Prasad
Publisher :
ISBN 13 :
Total Pages : 104 pages
Book Rating : 4.:/5 (318 download)
Download or read book Zinc in Human Nutrition written by Ananda Shiva Prasad and published by . This book was released on 1979 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt:
