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Testicular Autoimmunity
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Book Synopsis Testicular Autoimmunity by : Masahiro Itoh
Download or read book Testicular Autoimmunity written by Masahiro Itoh and published by Springer. This book was released on 2017-07-31 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses various aspects of testicular autoimmunity. It has long been suspected that testicular autoimmunity could be one of the causes of idiopathic male infertility. However, it is very difficult to estimate the incidence of testicular autoimmunity in men, as most male patients first realize they are infertile when they start trying to conceive a child, and there is a possibility that their testes may already exhibit the end stage of testicular autoimmunity, in which lymphocytic inflammation and immunoglobulin deposition in their testes subsided long ago and only the spermatogenic disorder remains. Therefore, autopsy or biopsy for testicular tissues in men before the end stage of testicular autoimmunity and investigations using testicular autoimmunity model animals are needed to determine the epidemiology of testicular autoimmunity. Accordingly, the book discusses “the immunological fragility of testis” with regard to male infertility, reviewing autopsy data in men and presenting experimental data using murine models of autoimmune orchitis that has been induced by immunizing with viable syngeneic testicular germ cells alone. Testicular autoimmunity in animals is also discussed. In summary, the book provides a wealth of valuable information, not only for researchers who are interested in immunologic male infertility, but also for clinical professionals who treat these patients at hospitals.
Book Synopsis Diagnostic Criteria in Autoimmune Diseases by : Yehuda Shoenfeld
Download or read book Diagnostic Criteria in Autoimmune Diseases written by Yehuda Shoenfeld and published by Springer Science & Business Media. This book was released on 2010-06-08 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to the Autoimmune Diseases Coordinating Committee (ADCC), between 14.7 and 23.5 million people in the USA – up to eight percent of the population are affected by autoimmune disease. Autoimmune diseases are a family of more than 100 chronic, and often disabling, illnesses that develop when underlying defects in the immune system lead the body to attack its own organs, tissues, and cells. In Handbook of Autoimmune Disease, the editors have gathered in a comprehensive handbook a critical review, by renowned experts, of more than 100 autoimmune diseases, divided into two main groups, namely systemic and organ-specific autoimmune diseases. A contemporary overview of these conditions with special emphasis on diagnosis is presented. Each chapter contains the essential information required by attending physicians as well as bench scientists to understand the definition of a specific autoimmune disease, the diagnostic criteria, and the treatment.
Book Synopsis Translational Autoimmunity, Volume 5 by : Nima Rezaei
Download or read book Translational Autoimmunity, Volume 5 written by Nima Rezaei and published by Elsevier. This book was released on 2022-09-13 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Autoimmunity: Challenges for Autoimmune Diseases, Fifth Edition addresses diagnostic approaches, therapeutic opportunities, and prognostic markers of different autoimmune diseases. This updated volume discusses autotoxicity, systems immunology, the prognostic significance of disease-specific autoantibodies, along with translational research to novel therapeutic policy in autoimmune diseases. From an introduction, to challenges and insights on the systems immunology of infectious and autoimmune diseases, new targets of treatments, and the role of autoantibodies in diagnosis and evolution, this book provides insights on many challenges researchers and clinicians are facing. - Describes challenges in the diagnosis, management and treatment of autoimmune diseases - Highlights major difficulties in the diagnosis and management of autoimmune diseases - Reflects important remediable deficiencies in current management - Meets the needs of basic scientists, clinicians and translational scientists and industry partners
Book Synopsis The Molecular Pathology of Autoimmune Diseases by : Argyrios N Theofilopoulos
Download or read book The Molecular Pathology of Autoimmune Diseases written by Argyrios N Theofilopoulos and published by CRC Press. This book was released on 2002-12-06 with total page 1518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Remarkable advances have been made in the pathogenesis of autoimmunity, such as with bone marrow transplantation, which is becoming a powerful strategy in treating certain life-threatening diseases. The Molecular Pathology of Autoimmune Diseases is a concise and centralized resource for information on the topic, with a special focus on the molecular and genetic basis of these disorders. Dozens of international experts devote themselves to illuminating the reader in this volume, with discussions on the basic aspects of autoimmune processes to systemic and organ-specific diseases. This volume is an invaluable reference to students and professionals in immunology and related fields.
Book Synopsis Good News - Bad News: The Two Faces of Immune Privilege by : Rachel R. Caspi
Download or read book Good News - Bad News: The Two Faces of Immune Privilege written by Rachel R. Caspi and published by Frontiers Media SA. This book was released on 2014-11-19 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immune privilege was once thought to be the property of a few select sites that include the eye, brain, testis, pregnant uterus and (of all things) the hamster cheek pouch, and was believed to be mainly based on sequestration behind blood-tissue barriers. This view has changed. Immune privilege is now considered to constitute a more general phenomenon through which tissues are able to actively direct and control immune responses taking place in their “territory” to preserve their structural and functional integrity in the face of inflammatory processes. These positive aspects of immune privilege can be hijacked by tumors to their survival advantage and to the detriment of the host. This Research Topic dissects the beneficial and deleterious consequences of immune privilege in terms of the cellular and molecular mechanisms that various tissues and tumors use, each in its own fashion, to regulate immune processes that affect them, at the local and the systemic level.
Author :Claude Desjardins Publisher :New York : Oxford University Press ISBN 13 :9780195062694 Total Pages :524 pages Book Rating :4.0/5 (626 download)
Book Synopsis Cell and Molecular Biology of the Testis by : Claude Desjardins
Download or read book Cell and Molecular Biology of the Testis written by Claude Desjardins and published by New York : Oxford University Press. This book was released on 1993 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive, multi-authored work on the structure and function of the mammalian testis. The approach emphasizes gene expression, translation and production of specific gene products and the cellular and molecular regulation of these fundamental processes. Rather than provide a global survey of all aspects of male reproduction, this book stresses specific mechanisms that underscore the structure and function of the testis. It explains old and new concepts from a cellular and molecular perspective. This novel approach allows the authors to forge links between cell and molecular biology and well-established aspects of spermatogenesis and steroidogenesis. The result is a well-focused, comprehensive, and synthetic analysis of testicular biology.
Book Synopsis Autoimmune Disease Models by : Irun R. Cohen
Download or read book Autoimmune Disease Models written by Irun R. Cohen and published by Academic Press. This book was released on 1994 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because autoimmune disorders can wreak havoc in both humans and animals, these disorders are now the objects of intense and focused research. This book details specific animal models for a variety of autoimmune disorders. The contributors are recognized authorities who deal with the panoply of experimentally induced autoimmune disorders, including encephalomyelitis, allergic neuritis, uveoretinitis, myocarditis, and hepatitis. Also included are discussions of spontaneously appearing diseases such as autoimmune thyroiditis and systemic lupus erythematosus. Many other disorders are also covered in this comprehensive guide. Certain to be an aid in the planning of individual experiments and broader research programs, this book will be a valuable addition to the library of all practicing immunologists interested in immune system function and dysfunction.
Book Synopsis The Autoimmune Diseases by : Bozzano G Luisa
Download or read book The Autoimmune Diseases written by Bozzano G Luisa and published by Academic Press. This book was released on 2012-12-02 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Autoimmune Diseases is composed of 25 chapters dealing with different aspects of some specific autoimmune diseases. The book begins with the elucidation of the genetic predisposition to autoimmune diseases. Subsequent chapters explore numerous kinds of autoimmune diseases. Other chapters describe the antireceptor antibodies and the sensitivity and specificity of autoantibody testing. This book is designed to provide a deeper understanding of this increasingly important field of medical science for physicians and investigators involved in the diagnosis, treatment, or research of autoimmune diseases.
Book Synopsis Infection, Immune Homeostasis and Immune Privilege by : Joan Stein-Streilein
Download or read book Infection, Immune Homeostasis and Immune Privilege written by Joan Stein-Streilein and published by Springer Science & Business Media. This book was released on 2012-07-03 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organs and tissues that can tolerate little or no inflammation have developed multiple overlapping mechanisms of immune protection in the absence of inflammation. These areas have been designated “immune-privileged sites” by Peter Medawar and include the central nervous system, eye, reproductive tract, testis and possibly the liver. Mechanisms of immune homeostasis found in less immune-regulated organs are often evident in the immune privileged sites and vice versa. It is important that the non-inflammatory mechanisms that contribute to immune privilege allow host defense against infectious organisms. This volume highlights the mechanisms leading to immune privilege in tissues and organs, the deviation of immune responses and the modification of the behavior of the immune cells that manage to cross the blood barriers of tissues, in the context of infection.
Book Synopsis Knobil and Neill's Physiology of Reproduction by : Tony M. Plant
Download or read book Knobil and Neill's Physiology of Reproduction written by Tony M. Plant and published by Academic Press. This book was released on 2014-11-15 with total page 2708 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Fourth Edition of Knobil & Neill continues to serve as a reference aid for research, to provide the historical context to current research, and most importantly as an aid for graduate teaching on a broad range of topics in human and comparative reproduction. In the decade since the publication of the last edition, the study of reproductive physiology has undergone monumental changes. Chief among these advances are in the areas of stem cell development, signaling pathways, the role of inflammation in the regulatory processes in the various tissues, and the integration of new animal models which have led to a greater understanding of human disease. The new edition synthesizes all of this new information at the molecular, cellular, and organismal levels of organization and present modern physiology a more understandable and comparative context. - The Fourth Edition has been extensively revised, reflecting new fundamental advancements in this rapidly advancing field. - Provides a common language for researchers across the fields of physiology, endocrinology, and biology to discuss their understanding of reproduction. - Saves academic researchers time in quickly accessing the very latest details on reproductive physiology, as opposed to searching through thousands of journal articles.
Book Synopsis The Autoimmune Diseases by : M. Eric Gershwin
Download or read book The Autoimmune Diseases written by M. Eric Gershwin and published by Academic Press. This book was released on 2013-12-03 with total page 1302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since publication of the 4th Edition of The Autoimmune Diseases in 2006, the understanding of the immune mechanisms underlying autoimmunity and autoimmune disease has significantly deepened and broadened. This fully revised 5th Edition incorporates new material and combines common themes underlying inductive and effector mechanisms and therapies that relate generally to the autoimmune disorders. It discusses the biological basis of disease at genetic, molecular, cellular, and epidemiologic levels and includes expanded coverage of autoinflammatory disease and autoimmune responses to tumors. - Gives a thorough and an important overview on the entire field, framing individual disease chapters with information that compares and contrasts each disorder and therapy - Provides thorough, up-to-date information on specific diseases, along with clinical applications, in an easily found reference for clinicians and researchers interested in certain diseases - Keeps readers abreast of current trends and emerging areas in the field - Ensures that content is not only up-to-date, but applicable and relevant
Book Synopsis Molecular Mechanisms in Spermatogenesis by : C.Yan Cheng
Download or read book Molecular Mechanisms in Spermatogenesis written by C.Yan Cheng and published by Springer Nature. This book was released on 2021-08-28 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition provides an update on the molecular mechanisms that regulate spermatogenesis. In addition to the rodent as a study model, chapters also include research on studies in humans. It includes the latest approaches of studying spermatogenesis, such as the use of bioinformatics, molecular modeling and others which are not commonly found in published materials. It also reviews the latest developments in the field, such as studies on the role of regulatory RNAs on spermatogenesis. Due to the declining fertility rate among men, a brand new chapter highlights the impact of environmental toxicants on spermatogenesis.
Book Synopsis Biological Factors—Advances in Research and Application: 2012 Edition by :
Download or read book Biological Factors—Advances in Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 755 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological Factors—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Biological Factors. The editors have built Biological Factors—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biological Factors in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Biological Factors—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis Knobil and Neill's Physiology of Reproduction by :
Download or read book Knobil and Neill's Physiology of Reproduction written by and published by Academic Press. This book was released on 2005-12-12 with total page 3269 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 3rd edition, the first new one in ten years, includes coverage of molecular levels of detail arising from the last decade's explosion of information at this level of organismic organization. There are 5 new Associate Editors and about 2/3 of the chapters have new authors. Chapters prepared by return authors are extensively revised. Several new chapters have been added on the topic of pregnancy, reflecting the vigorous investigation of this topic during the last decade.The information covered includes both human and experimental animals; basic principels are sought, and information at the organismic and molecular levels are presented.*The leading comprehensive work on the physiology of reproduction*Edited and authored by the world's leading scientists in the field*Is a synthesis of the molecular, cellular, and organismic levels of organization*Bibliogrpahics of chapters are extensive and cover all the relevant literature
Download or read book Spermatogenesis written by C. Yan Cheng and published by CRC Press. This book was released on 2018-09-03 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Senior investigators internationally have here collaborated to produce an international reference work. Each contributor provides critical and thought provoking concepts and ideas based on the latest developments in their field. The result is a must read and timely reference work for investigators who are interested in how spermatogenesis is currently understood and which are the most promising avenues for future research; an Introduction sets the context for the chapter and points out the relevance of the research for basic research scientists and clinicians.
Book Synopsis The Encyclopedia of Autoimmune Diseases by : Dana K. Cassell
Download or read book The Encyclopedia of Autoimmune Diseases written by Dana K. Cassell and published by Infobase Publishing. This book was released on 2014-05-14 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive guide to diseases of the immune system, listing names, symptoms, research, treatments available and more.
Book Synopsis Biomedical Index to PHS-supported Research by :
Download or read book Biomedical Index to PHS-supported Research written by and published by . This book was released on 1991 with total page 1104 pages. Available in PDF, EPUB and Kindle. Book excerpt:
