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Telomeres In Health And Disease
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Book Synopsis Telomeres in Health and Disease by :
Download or read book Telomeres in Health and Disease written by and published by Academic Press. This book was released on 2014-06-26 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: This special volume of Progress in Molecular Biology and Translational Science focuses on telomeres in health and disease. This volume covers a variety of topics with reviews written by experts in the field. Contributions from specialists in telomere diseases Informs and updates on how telomere dysfunction may cause disease in humans
Book Synopsis Telomeres and Telomerase by : Predrag Slijepcevic
Download or read book Telomeres and Telomerase written by Predrag Slijepcevic and published by S. Karger AG (Switzerland). This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Telomeres are essential functional elements of eukaryotic chromosomes. Their fundamental biological role as protectors of chromosome stability was identified for the first time in the 1930s by Hermann Muller and Barbara McClintock based on pioneering cytological experiments. Modern molecular research carried out more recently revealed that telomeres and telomerase play important roles in processes such as carcinogenesis and cellular senescence. This special issue presents the most recent developments in this highly active field of research. It is becoming increasingly clear that molecular pathways involved in regulation of telomere length and structure are functionally linked with pathways involved in DNA damage response, cellular stress response, chromatin organization and perhaps even pathways that regulate evolutionary chromosome rearrangements. The above functional link is explored by the leading experts in the field of telomere biology. Cell biologists, molecular biologists, oncologists, gerontologists, and radiobiologists with an interest in the role of telomeres/telomerase will appreciate the up-to-date information in this publication.
Book Synopsis The Telomere Effect by : Dr. Elizabeth Blackburn
Download or read book The Telomere Effect written by Dr. Elizabeth Blackburn and published by Grand Central Publishing. This book was released on 2017-01-03 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: The New York Times bestselling book coauthored by the Nobel Prize winner who discovered telomerase and telomeres' role in the aging process and the health psychologist who has done original research into how specific lifestyle and psychological habits can protect telomeres, slowing disease and improving life. Have you wondered why some sixty-year-olds look and feel like forty-year-olds and why some forty-year-olds look and feel like sixty-year-olds? While many factors contribute to aging and illness, Dr. Elizabeth Blackburn discovered a biological indicator called telomerase, the enzyme that replenishes telomeres, which protect our genetic heritage. Dr. Blackburn and Dr. Elissa Epel's research shows that the length and health of one's telomeres are a biological underpinning of the long-hypothesized mind-body connection. They and other scientists have found that changes we can make to our daily habits can protect our telomeres and increase our health spans (the number of years we remain healthy, active, and disease-free). The Telemere Effect reveals how Blackburn and Epel's findings, together with research from colleagues around the world, cumulatively show that sleep quality, exercise, aspects of diet, and even certain chemicals profoundly affect our telomeres, and that chronic stress, negative thoughts, strained relationships, and even the wrong neighborhoods can eat away at them. Drawing from this scientific body of knowledge, they share lists of foods and suggest amounts and types of exercise that are healthy for our telomeres, mind tricks you can use to protect yourself from stress, and information about how to protect your children against developing shorter telomeres, from pregnancy through adolescence. And they describe how we can improve our health spans at the community level, with neighborhoods characterized by trust, green spaces, and safe streets. The Telemere Effect will make you reassess how you live your life on a day-to-day basis. It is the first book to explain how we age at a cellular level and how we can make simple changes to keep our chromosomes and cells healthy, allowing us to stay disease-free longer and live more vital and meaningful lives.
Download or read book Telomere Miracle written by Ed Park, MD and published by Hay House, Inc. This book was released on 2018-01-23 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: What if everything you think you know about getting older and staying healthy is wrong? Ed Park, M.D., offers the revolutionary idea that disease and aging in humans all arises from a single source: genetic errors caused by shortening of telomeres, or the sequences of DNA at the ends of our chromosomes. Telomeres naturally wear down over time, and thus when cells replicate (as they do all the time in our bodies), they’re creating progressively poorer-quality duplicates of themselves, like making a Xerox of a Xerox of a Xerox. Ultimately, the body deteriorates, resulting in a range of ailments, many of which we associate with aging—from diabetes to hypertension to macular degeneration to cancer. Happily, Ed tells us, it’s possible to slow or even reverse this process and effectively turn back the clock. In The Telomere Miracle, he explains cutting-edge science in a lively style, using illustrations and metaphors ranging from auto parts to superheroes. Then he shows readers how they can intervene in the aging process by boosting the activity of the enzyme telomerase naturally by understanding and optimizing six key areas of breathing, mindset, sleep, exercise, diet, and supplements.
Book Synopsis Telomeres, Diet and Human Disease by : Amelia Marti
Download or read book Telomeres, Diet and Human Disease written by Amelia Marti and published by CRC Press. This book was released on 2017-08-30 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The maintenance of telomeres—repetitive sequences at the end of chromosome—is essential to health. Dysfunction in telomere maintenance pathways plays a role in aging, cancer, atherosclerosis and other diseases. This has led to telomere maintenance as a prime target for patient therapies. This book describes the advances in telomere research as it applies to human health and especially how lifestyle and dietary factors could modify the telomerase maintenance process. The book examines the mechanisms involved, the primary of which are oxidative stress and the role of sirtuins, and how they can be modified by dietary patterns such as Mediterranean diet.
Book Synopsis Telomeres and Telomerase in Cancer by : Keiko Hiyama
Download or read book Telomeres and Telomerase in Cancer written by Keiko Hiyama and published by Springer Science & Business Media. This book was released on 2009-03-18 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Telomerase, an enzyme that maintains telomeres and endows eukaryotic cells with immortality, was first discovered in tetrahymena in 1985. In 1990s, it was proven that this enzyme also plays a key role in the infinite proliferation of human cancer cells. Now telomere and telomerase are widely accepted as important factors involved in cancer biology, and as promising diagnostic tools and therapeutic targets. Recently, role of telomerase in “cancer stem cells” has become another attractive story. Until now, there are several good books on telomere and telomerase focusing on biology in ciliates, yeasts, and mouse or basic sciences in human, providing basic scientists or students with updated knowledge.
Book Synopsis Telomeres and Telomerase in Aging, Disease, and Cancer by : K. Lenhard Rudolph
Download or read book Telomeres and Telomerase in Aging, Disease, and Cancer written by K. Lenhard Rudolph and published by Springer Science & Business Media. This book was released on 2007-11-07 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Telomere shortening represents one of the basic aspects of ageing and telomere dysfunction could contribute to the accumulation of DNA damage during ageing. This book summarizes evidence and data indicating that telomere dysfunction influences human ageing, diseases and cancer. The book describes our current knowledge on checkpoints that limit cellular lifespan and survival in response to telomere dysfunction. There is special focus on adult stem cells.
Book Synopsis The Telomere Effect by : Elizabeth Blackburn
Download or read book The Telomere Effect written by Elizabeth Blackburn and published by Hachette UK. This book was released on 2017-01-03 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the Best 'Brainy' Books of This Decade - The Guardian A ground breaking book on the history of Telomeres offering fresh advice on how to slow down aging and lengthen life. Nobel prize winning Doctor Elizabeth Blackburn and leading health psychologist Dr Elissa Epel have discovered biological markers called Telomeres which can help to understand how healthy our cells are and what we can do to improve them. The book specifically looks ideas including; how biological age is not chronological age; a biological basis for the mind-body connection, how sleep and diet can affect telomeres and shockingly how mothers who are highly stressed during pregnancy have children with shorter telomeres. It also offers tools and advice on how to determine cellular age and telomere health. Doctor Elizabeth Blackburn was awarded the Nobel Prize in Physiology or Medicine in 2009 for her discovery of telomeres and their role in the ageing process and has previously been named in TIME magazine's 100 Most Influential People. Dr. Elissa Epel is a leading health psychologist who has conducted pioneering research uncovering the psychobiological mechanisms related to how stress ages us and compromises our health-from emotional eating to unhealthy storage of abdominal fat to telomere shortening.
Download or read book Lifelines written by Elaine Chin and published by Figure 1 Publishing. This book was released on 2015-09-15 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unlock the secrets of your telomeres for a longer, healthier life. They’re like the plastic tips of your shoelaces that keep them from fraying. But they’re at the ends of your DNA and they keep you from developing disease and dying too young. The discovery of telomeres is one of the great breakthroughs in contemporary medicine. Nobel-winning scientist Dr. Elizabeth Blackburn and her research teams have opened a world of promise when it comes to living longer and healthier. Today, we have the know-how to slow the disintegration process, to beat our biological clock, and prevent disease. Keeping your telomeres robust and as long as possible is crucial to your health. Noted physician, Dr. Elaine Chin, offers practical and realistic ways to optimize the length of your telomeres and maximize your health. Containing comprehensive information on diet and lifestyle, the potential of supplements, hormone-replacement therapy, sleep patterns, mindfulness, stress management and life purpose, Lifelines will show you how to use our knowledge of telomere science to give you an advantage in what really counts most in life—how long and how well you will live!
Book Synopsis Telomere Territory and Cancer by : Parvin Mehdipour
Download or read book Telomere Territory and Cancer written by Parvin Mehdipour and published by Springer Science & Business Media. This book was released on 2012-08-13 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Timing, racing, combating, struggling and targeting are some actions through which cellular fate could be reflected and evaluated. Interaction between cell territory and environment occur during pre-embryonic, fetal development, and post-natal periods. What the researchers observe as the outcome of telomeres behavior is only the peak of an ice mountain within a stormy ocean. Cellular life depends on programmed behavior of telomeres, capable to surprise the cells. Telomeres provide an introduction to the history of our cells which govern the quality of life and status of health. Telomeres as the cooperative territory are capable of stabilizing the chromosomal territory. The status of telomeres reflects the key information, announcing the real age of individuals, and may be a valuable marker for prognosis and predicting cancer. Telomere territory is characterized with a multi-disciplinary manner. Therefore, this book is aimed to offer a wide range of chapters, hoping to be useful for diverse audiences, including hematologists-oncologists, radiotherapists, surgeons, cancer researchers, and all the sectors who affect the macro- and micro- environmental domains. Finally, telomeres are sensitive, cooperative, and trustable targets. It is worth to state that ‘telomeres are messengers of NATURE’, let’s to know them as they are.
Book Synopsis Comprehensive Geriatric Oncology by : Lodovico Balducci
Download or read book Comprehensive Geriatric Oncology written by Lodovico Balducci and published by CRC Press. This book was released on 2004-03-01 with total page 896 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published in 2004: This new edition of Comprehensive Geriatric Oncology still offers an exhaustive review of the biology of cancer and aging, of the epidemiologic trends in the country and in the world, and of the clinical trials that concern cancer prevention and cancer treatment in the elderly.
Book Synopsis The Immortality Edge by : Michael Fossel
Download or read book The Immortality Edge written by Michael Fossel and published by Turner Publishing Company. This book was released on 2010-11-19 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on Nobel Prize–winning genetic research-a simple plan to keep your telomeres healthy for better health and longevity Telomeres play an important role in protecting our chromosomes from critical damage. The shortening of the telomere disrupts vital cellular function and promotes the previously seemingly inevitable onset of aging and various diseases, including cancer and Alzheimer's. Drawing from the groundbreaking discoveries about telomeres that won the 2009 Nobel Prize in Medicine, this book includes a highly prescriptive program that shows you how to live longer by slowing telomere shortening and rejuvenating your cells through relatively simple alterations in nutrition habits and other lifestyle changes. Written by authors with extensive knowledge of genetics, telomeres, and longevity Offers a simple action plan you can start using immediately Includes a revolutionary new eating plan Recommends individualized supplement programs Shares a diet and exercise approach grounded in solid scientific research The exciting recent discoveries about telomeres promise to revolutionize our approach to anti-aging much as antioxidants did ten years ago. Unlike trendy diet and fitness books with no basis in science, The Immortality Edge targets health at its innermost level by laying out a realistic, lifelong plan using easy steps that can fit into any busy schedule-steps that can improve the length and quality of your life.
Book Synopsis Telomeres, Diet and Human Disease by : Taylor & Francis Group
Download or read book Telomeres, Diet and Human Disease written by Taylor & Francis Group and published by CRC Press. This book was released on 2021-03-31 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: The maintenance of telomeres--repetitive sequences at the end of chromosome--is essential to health. Dysfunction in telomere maintenance pathways plays a role in aging, cancer, atherosclerosis and other diseases. This has led to telomere maintenance as a prime target for patient therapies. This book describes the advances in telomere research as it applies to human health and especially how lifestyle and dietary factors could modify the telomerase maintenance process. The book examines the mechanisms involved, the primary of which are oxidative stress and the role of sirtuins, and how they can be modified by dietary patterns such as Mediterranean diet.
Download or read book Telomere Biology written by Jerome Fucile and published by . This book was released on 2015-03-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book extensively discusses the biology of telomere with the help of advanced information. Developments in telomere researches have provided an interrelation of telomere dysfunction with cellular aging and several age-related human diseases. Some new findings and studies have further widened our knowledge of telomere functions, where telomeres have been demonstrated to be essential for microbial pathogen virulence and telomere proteins have significant non-telomeric cellular functions. This book presents current opinions on selected areas of telomere research and their implication, in the hope of benefitting interested individuals in their future studies and enhancing their research progress.
Book Synopsis Heineken lectures 2004 by : Elizabeth H. Blackburn
Download or read book Heineken lectures 2004 written by Elizabeth H. Blackburn and published by . This book was released on 2004 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Telomere Diet & Cookbook by : Maggie Moon
Download or read book Telomere Diet & Cookbook written by Maggie Moon and published by Simon and Schuster. This book was released on 2019-09-17 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: A delicious way to hack your DNA and prevent early agingWhile some enjoy extremely active and healthy lives as they age, others spend years of their life burdened by heart disease, dementia, and other age-related diseases. Until recently, this was often chalked up to luck or “good genes.” But fascinating new research suggests that telomeres, the protective caps on your chromosomes, are actually directly linked to aging. Telomeres, when protected, can lead to a longer, happier life.Fortunately, one of the key components to protecting your telomeres is a balanced diet. The Telomere Diet and Cookbook is the first book to offer an easy-to-read, targeted overview of telomeres and nutrition. Including detailed meal plans and shopping lists, this book offers a simple step-by-step starter program and over 75 delicious recipes.
Book Synopsis The Telomerase Revolution by : Michael Fossel
Download or read book The Telomerase Revolution written by Michael Fossel and published by Atlantic Books Ltd. This book was released on 2015-10-06 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science is on the cusp of a revolutionary breakthrough. We now understand more about ageing - and how to prevent and reverse it - than ever before. In The Telomerase Revolution, Dr Michael Fossel, who has been at the cutting edge of ageing research for decades, describes how telomerase will soon be used as a powerful therapeutic tool, with the potential to intervene in age-related disease, dramatically extend life spans and even reverse human ageing. Telomerase-based treatments are already on offer, and have shown early promise, but much more potent treatments will become available over the next decade. This is the definitive work on the latest science of human ageing, covering both the theory and the clinical implications, taking readers to the forefront of one of the most remarkable advances in human medicine.
