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Author :
Publisher :
ISBN 13 :
Total Pages : 420 pages
Book Rating : 4.5/5 (418 download)
Download or read book Targets in Heterocyclic Systems written by and published by . This book was released on 1997 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 446 pages
Book Rating : 4.6/5 (53 download)
Download or read book Targets in Heterocyclic Systems written by and published by . This book was released on 1997 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Vivek Asati
Publisher : Elsevier
ISBN 13 : 0323996329
Total Pages : 504 pages
Book Rating : 4.3/5 (239 download)
Download or read book Current Molecular Targets of Heterocyclic Compounds for Cancer Therapy written by Vivek Asati and published by Elsevier. This book was released on 2024-04-10 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Molecular Targets of Heterocyclic Compounds for Cancer Therapy discusses recently developed treatments based on molecular targets which are genetically altered in cancer cells and are essential for tumor development and survival. Considerable research effort has been devoted to the development of targeted drugs that inhibit the action of pathogenic kinases, and clinical studies performed so far have validated the positive effects of kinase inhibitors for cancer treatment. Each chapter discusses a molecular target, such as ALK2, ATR, CK, Src-Abl, EGFR, Fyn-Blk-Lyn, IGFs, and PAK1. The book's chapters are written by experts who actively work on the targets to help readers fully understand how they can be used. This is a valuable resource for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in the potential of novel cancer therapies based on molecular targets. - Discusses recently discovered molecular targets for cancer therapy - Brings updated literature of heterocyclic compounds, an important construction motif for the development of new anticancer drugs - Encompasses comprehensive compilation of recently introduced anticancer drugs in the market and their health outcomes and pharmacoeconomics
Author : Orazio A. Attanasi
Publisher :
ISBN 13 : 9788886208567
Total Pages : 0 pages
Book Rating : 4.2/5 (85 download)
Download or read book Targets in Heterocyclic Systems written by Orazio A. Attanasi and published by . This book was released on 2009-07-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 11 keeps the international standard of the THS series, covering the synthesis, reactivity, activity (including medicinal) and mass spectrometry of different systems.
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Publisher : Academic Press
ISBN 13 : 0128209860
Total Pages : 306 pages
Book Rating : 4.1/5 (282 download)
Download or read book Advances in Heterocyclic Chemistry written by and published by Academic Press. This book was released on 2021-02-23 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Heterocyclic Chemistry, Volume 133 is the latest release in this definitive series of great importance to organic chemists, polymer chemists, and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature also is being used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive review contains comprehensive chapters on Organosilicon azoles: Structure, silylotropy and NMR spectroscopy, Recent advances in the Nenitzescu indole synthesis (1990–2019), One-pot reactions of three-membered rings giving N,O,S-heterocycles, Organometallic complexes of functionalized chelating azines: Part 2, and more. Presents the definitive serial in the field of heterocyclic chemistry Serves as the go-to reference for organic chemists, polymer chemists and many biological scientists Provides the latest comprehensive reviews as written by established authorities in the field Combines descriptive synthetic chemistry and mechanistic insight to enhance understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds
Author : Kristian Nylund
Publisher :
ISBN 13 : 9781608763689
Total Pages : 0 pages
Book Rating : 4.7/5 (636 download)
Download or read book Heterocyclic Compounds written by Kristian Nylund and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heterocyclic compounds are organic compounds containing at least one atom of carbon, and at least one element other than carbon, such as sulphur, oxygen or nitrogen within a ring structure. These structures may comprise either simple aromatic rings or non-aromatic rings. Some examples are pyridine (C5H5N), pyrimidine (C4H4N2) and dioxane (C4H8O2). Many heterocyclic compounds, including some amines, are carcinogenic. This book details the proposed mechanisms of Gewald-like reactions and the wide scope of substituted 2-aminothiophenes for real life applications. Literary information about synthesis methods, structure, physical-chemical and biological properties is summarised, and also information about conversion of adamantyl-1 and adamantyl-2 imidazole and benzimidazole derivatives is given. In addition, 3-acetylindole derivatives have been in the centre of attention of researchers over many years due to the high practical value of these compounds. This book presents a survey of the literature on 3-acetylindoles chemistry and provides useful and up-to-date data for medicinal chemists.
Author : Julio Alvarez-Builla
Publisher : John Wiley & Sons
ISBN 13 : 3527332014
Total Pages : 2531 pages
Book Rating : 4.5/5 (273 download)
Download or read book Modern Heterocyclic Chemistry, 4 Volumes written by Julio Alvarez-Builla and published by John Wiley & Sons. This book was released on 2011-08-15 with total page 2531 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eine Fülle von Information zum attraktiven Preis bietet Ihnen dieses vierbändige Handbuch der Heterocyclenchemie.
Author : Charles K. Zercher
Publisher : John Wiley & Sons
ISBN 13 : 1118117824
Total Pages : 1606 pages
Book Rating : 4.1/5 (181 download)
Download or read book Organic Syntheses, Collective Volume 12 written by Charles K. Zercher and published by John Wiley & Sons. This book was released on 2015-10-19 with total page 1606 pages. Available in PDF, EPUB and Kindle. Book excerpt: Continuing the tradition of providing significant and interesting procedures, Organic Syntheses, Collective Volume XII is a compilation of revised editions of Annual Volumes 85 through 89. The contents of this volume are organized by primarily by reaction type, with the precise classification made according to the bias of the editor, who attempted to ascertain the primary purpose or utility of the procedure.
Author : Axel Griesbeck
Publisher : CRC Press
ISBN 13 : 1466561254
Total Pages : 1607 pages
Book Rating : 4.4/5 (665 download)
Download or read book CRC Handbook of Organic Photochemistry and Photobiology, Third Edition - Two Volume Set written by Axel Griesbeck and published by CRC Press. This book was released on 2019-04-05 with total page 1607 pages. Available in PDF, EPUB and Kindle. Book excerpt: The only combined organic photochemistry and photobiology handbookAs spectroscopic, synthetic and biological tools become more and more sophisticated, photochemistry and photobiology are merging-making interdisciplinary research essential. Following in the footsteps of its bestselling predecessors, the CRC Handbook of Organic Photochemistry and Pho
Author : David W Allen
Publisher : Royal Society of Chemistry
ISBN 13 : 1847555276
Total Pages : 575 pages
Book Rating : 4.8/5 (475 download)
Download or read book Organophosphorus Chemistry written by David W Allen and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organophosphorus Chemistry provides a comprehensive annual review of the literature. Coverage includes phosphines and their chalcogenides, phosphonium salts, low coordination number phosphorus compounds, penta- and hexa-coordinated compounds, tervalent phosphorus acids, nucleotides and nucleic acids, ylides and related compounds, and phosphazenes. The series will be of value to research workers in universities, government and industrial research organisations, whose work involves the use of organophosphorus compounds. It provides a concise but comprehensive survey of a vast field of study with a wide variety of applications, enabling the reader to rapidly keep abreast of the latest developments in their specialist areas. Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.
Author : United States. Public Health Service. Office of the Surgeon General
Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Author :
Publisher :
ISBN 13 :
Total Pages : 624 pages
Book Rating : 4.:/5 (318 download)
Download or read book Heterocycles written by and published by . This book was released on 2008 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Academic Press
ISBN 13 : 0323988628
Total Pages : 454 pages
Book Rating : 4.3/5 (239 download)
Download or read book Heterocyclic Mesomeric Betaines and Mesoionic Compounds written by and published by Academic Press. This book was released on 2022-03-16 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heterocyclic Mesomeric Betaines and Mesoionic Compounds, Volume 137 in the Advances in Heterocyclic Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Heterocyclic Mesomeric Betaines, Type A Mesoionic Compounds (1980-2020), Type B Mesoionic Compounds (1980-2020), Recent Developments in the Chemistry of Heteroporphyrins, Carbaporphyrins and Related Systems, Heterocyclic Zwitterions Based on Coupled Polymethines, Meso-ionic Compounds reproduced from Adv. Heterocycl. Chem. 1976, 19, 1-122., and Meso-ionic Heterocycles (1976-1980) reproduced from Tetrahedron, 1982, 38, 2965-3011. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in Advances in Heterocyclic Chemistry series - Updated release includes the latest information on Betaine
Author : Gordon W. Gribble
Publisher : John Wiley & Sons
ISBN 13 : 1118683056
Total Pages : 704 pages
Book Rating : 4.1/5 (186 download)
Download or read book Indole Ring Synthesis written by Gordon W. Gribble and published by John Wiley & Sons. This book was released on 2016-06-06 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of the myriad of heterocycles known to man, the indole ring stands foremost for its remarkably versatile chemistry, its enormous range of biological activities, and its ubiquity in the terrestrial and marine environments. The indole ring continues to be discovered in natural products and to be employed in man-made pharmaceuticals and other materials. Given the enormous resurgence in indole ring synthesis over the past decade — highlighted by the power of transition metal catalysis — this authoritative guide addresses the need for a comprehensive presentation of the myriad of methods for constructing the indole ring, from the ancient to the modern, and from the obscure to the well-known. Following presentation of the classic indole ring syntheses and many newer methods, coverage continues with indole ring syntheses via pyrroles, indolines, oxindoles, isatins, radical and photochemical reactions, aryne cycloadditions. This extensive volume concludes with the modern transition metal–catalyzed indole ring syntheses that utilize copper, palladium, rhodium, gold, ruthenium, platinum, and other metals to fashion the indole ring Indole Ring Synthesis is a comprehensive, authoritative and up-to-date guide to the synthesis of this important heterocycle for organic chemists, pharmaceutical researchers and those interested in the chemistry of natural products.
Author : Corrado Tringali
Publisher : CRC Press
ISBN 13 : 1439870667
Total Pages : 648 pages
Book Rating : 4.4/5 (398 download)
Download or read book Bioactive Compounds from Natural Sources written by Corrado Tringali and published by CRC Press. This book was released on 2011-09-27 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of Bioactive Compounds from Natural Sources was published in a period of renewed attention to biologically active compounds of natural origin. This trend has continued and intensified-natural products are again under the spotlight, in particular for their possible pharmacological applications. Largely focusing on natural products
Author : Eugene V. Babaev
Publisher : Springer
ISBN 13 : 3319500155
Total Pages : 123 pages
Book Rating : 4.3/5 (195 download)
Download or read book Incorporation of Heterocycles into Combinatorial Chemistry written by Eugene V. Babaev and published by Springer. This book was released on 2016-12-01 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: The author has summarized a decade of teaching combinatorial chemistry into this timely brief. The solid phase synthesis of unnatural heterocyclic alpha-amino acids is illustrated by practical examples starting from the ABCs of peptide synthesis explored in chapter one. Chapter two is concerned with the solid phase synthesis which is shown on various techniques – BillBoard, tea-bag, and Lantern devices, and demonstrated on heterocyclic examples and protocols. In the third chapter the tools for accelerating chemical synthesis – solid phase and liquid phase – are reviewed. Here the techniques of parallel refluxing (including microwave and flow technique) and parallel separation (filtration, centrifugation, evaporation, and chromatography) are described. In the chapters 4 and 5 the author goes on to describe how the liquid phase synthesis of heterocycles (reductive amination and Ugi reaction of heterocycles) is illustrated with the use of semi-automated protocols. Finally, the design of combinatorial libraries of heterocycles is reviewed including the original author’s findings.
Author : Matthias D’hooghe
Publisher : Springer
ISBN 13 : 3319249606
Total Pages : 376 pages
Book Rating : 4.3/5 (192 download)
Download or read book Synthesis of 4- to 7-membered Heterocycles by Ring Expansion written by Matthias D’hooghe and published by Springer. This book was released on 2015-12-14 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal.
