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Targeting Stem Journal
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Book Synopsis Targeting STEM Journal by : Tim Tuck
Download or read book Targeting STEM Journal written by Tim Tuck and published by . This book was released on 2021 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The Year 3 Targeting STEM Journal is an exciting combination of Science, Technology, Engineering and Mathematics. It provides 42 projects for students to work on independently or in groups using a range of commonly available resources. Each project contains four steps with a picture list of requirements and just enough explanation for launching students on their journeys of discovery." -- Publisher's website.
Book Synopsis Targeting STEM Journal by : Tim Tuck
Download or read book Targeting STEM Journal written by Tim Tuck and published by . This book was released on 2021 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The Year 4 Targeting STEM Journal is an exciting combination of Science, Technology, Engineering and Mathematics. It provides 42 projects for students to work on independently or in groups using a range of commonly available resources. Each project contains four steps with a picture list of requirements and just enough explanation for launching students on their journeys of discovery." -- Publisher's website.
Book Synopsis Targeting STEM Journal by : Tim Tuck
Download or read book Targeting STEM Journal written by Tim Tuck and published by . This book was released on 2021 with total page 87 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The Year 6 Targeting STEM Journal is an exciting combination of Science, Technology, Engineering and Mathematics. It provides 42 projects for students to work on independently or in groups using a range of commonly available resources. Each project contains four steps with a picture list of requirements and just enough explanation for launching students on their journeys of discovery." -- Publisher's website.
Book Synopsis Targeting Signaling Pathways in Solid Tumors Part A by :
Download or read book Targeting Signaling Pathways in Solid Tumors Part A written by and published by Elsevier. This book was released on 2024-04-23 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeting Signaling Pathways in Solid Tumors, Part A, Volume 385 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Drugging the Undruggable: Advances in Targeting KRAS Signaling in Solid Tumors, Emerging Trends in Gastrointestinal Cancers: Targeting Developmental Pathways in their Carcinogenesis and Tumor Progression, Importance of targeting various cell signaling pathways in solid cancers, Targeting signaling pathways in cancer stem cells: a potential approach for developing novel anticancer therapeutics, Factors affecting heterogeneity in breast cancer microenvironment: A narrative review, and much more. Additional sections cover Exploring TLR Signaling Pathways as Promising Targets in Cervical Cancer: The Road Less Travelled Provides the latest information on cancer research Offers outstanding and original reviews on a range of cancer research topics Serves as an indispensable reference for researchers and students alike
Book Synopsis Targeted Radionuclide Tumor Therapy by : Torgny Stigbrand
Download or read book Targeted Radionuclide Tumor Therapy written by Torgny Stigbrand and published by Springer Science & Business Media. This book was released on 2008-09-01 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last three decades have provided opportunities to explore the potential of treating malignant diseases with antibodies or other targeting molecules labelled with nuclides. While considerable advances have been reported, there is still a signi- cant amount of work left to accomplish before our ambitions can be achieved. It now seems timely to review the accomplishments achieved to date and to clarify the challenges that remain. The choice of radionuclide, the conjugation p- cedure employed, and the selection of suitable targets were early issues that were faced by our field that still persist, however we can now tackle these obstacles with significantly better insight. The expanding array of new targeting molecules (recombinant antibodies, peptides and agents based upon alternate scaffolds) may increase the therapeutic efficacy or even modify the radiation sensitivity of the targeted tumor cell. The title of this book “Targeted Radionuclide Tumour Therapy – Biological Aspects” was selected to reinforce the concept that a major focus of this volume was devoted to understanding the biological effects of targeting and radiation. These important issues have not previously been the primary focus in this context. Furthermore, our rapidly expanding knowledge of different types of cell death and the increasingly likely existence of cancer stem cells suggests to us that even more efficient approaches in targeting might be possible in the future.
Book Synopsis Targeting Notch in Cancer by : Lucio Miele
Download or read book Targeting Notch in Cancer written by Lucio Miele and published by Springer. This book was released on 2018-11-23 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: The serendipitously discovered link between developmental biology and cancer, touched of an explosion of discoveries on the role of Notch in human malignancies, including every aspect of cancer biology, from control of differentiation, proliferation and apoptosis in transformed cells to angiogenesis, tumor-stroma interaction and anti-cancer immune responses. A number of observations have revealed that Notch even plays a role in the renewal of cancer stem cells and tumor initiating cells, which are thought to be a major cause of resistance to treatment. Targeting Notch in Cancer will provide researchers, oncologists, pharmacologists and students with a detailed understanding of the intricate cross-talk between Notch and other pathways of therapeutic interest so to better design rational drug combinations for specific diseases and disease subsets. Divided into two parts, Part I describes in detail what we know about the genetics, molecular biology, biochemistry and structural biology of Notch, as well as the role of Notch in such processes as angiogenesis and immune surveillance. Without insights gained from these basic studies, rational targeting of Notch in human disease would be impossible. Part II describes the role of Notch and ongoing experimental therapeutic efforts in the most important subtypes of human cancers, organized in a clinically oriented fashion by organs and systems affected
Book Synopsis Prodrugs and Targeted Delivery by : Jarkko Rautio
Download or read book Prodrugs and Targeted Delivery written by Jarkko Rautio and published by John Wiley & Sons. This book was released on 2011-01-11 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational design of prodrugs, beginning at the early stages of the development process, as well as discussing organ- and site-selective prodrugs. Every company employing medicinal chemists will be interested in this practice-oriented overview of a key strategy in modern drug discovery and development.
Book Synopsis Organelle and Molecular Targeting by : Lara Scheherazade Milane
Download or read book Organelle and Molecular Targeting written by Lara Scheherazade Milane and published by CRC Press. This book was released on 2021-12-29 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: We have surpassed the omics era and are truly in the Age of Molecular Therapeutics. The fast-paced development of SARS-CoV-2 vaccines, such as the mRNA vaccines encoding the viral spike protein, demonstrated the need for and capability of molecular therapy and nanotechnology-based solutions for drug delivery. In record speed, the SARS-CoV-2 viral RNA genome was sequenced and shared with the scientific community, allowing the rapid design of molecular therapeutics. The mRNA vaccines exploit the host cell endoplasmic reticulum to produce viral spike proteins for antigen presentation and recognition by the innate and adaptive immune system. Lipid nanoparticles enable the delivery of the fragile, degradation-sensitive nucleic acid payloads. Molecular-based therapeutics and nanotechnology solutions continue to drive the scientific and medical response to the COVID-19 pandemic as new mRNA, DNA, and protein-based vaccines are developed and approved and the emergency use approved vaccines are rapidly manufactured and distributed throughout the globe. The need for molecular therapies and drug delivery solutions is clear, and as these therapies progress and become more specialized there will be important advancements in organelle targeting. For example, using organelle targeting to direct lipid nanoparticles with mRNA payloads to the endoplasmic reticulum would increase the efficacy of mRNA vaccines, reducing the required dose and therefore the biomanufacturing demand. Likewise, improving the delivery of DNA therapeutics to the nucleus would improve efficacy. Organelles and molecules have always been drug targets, but until recently we have not had the tools or capability to design and develop such highly specific therapeutics. Organelle targeting has far-reaching implications. For example, mitochondria are central to both energy production and intrinsic apoptosis. Effectively targeting and manipulating mitochondria has therapeutic applications for diseases such as myopathies, cancer, neurodegeneration, progerias, diabetes, and the natural aging process. The SARS-CoV-2 vaccines that exploit the endoplasmic reticulum (for mRNA vaccines) and the nucleic translational process (DNA vaccines) attest to the need for organelle and molecular therapeutics. This book covers the status, demand, and future of organelle- and molecularly targeted therapeutics that are critical to the advancement of modern medicine. Organelle and molecular targeting is the drug design and drug delivery approach of today and the future; understanding this approach is essential for students, scientists, and clinicians contributing to modern medicine.
Book Synopsis Using New Metabolic Approaches to Target and Eradicate Cancer Stem Cells by : Michael P. Lisanti
Download or read book Using New Metabolic Approaches to Target and Eradicate Cancer Stem Cells written by Michael P. Lisanti and published by Frontiers Media SA. This book was released on 2022-07-14 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topic Editors MPL and FS hold a minority interest in Lunella Biotech, Inc.
Book Synopsis Targeting Maths Dictionary by : Garda Turner
Download or read book Targeting Maths Dictionary written by Garda Turner and published by Pascal Press. This book was released on 2003 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: This dictionary is an essential guide to the mathematical language an d concepts used in Australian Primary Schools. Written with the young re ader in mind, this dictionary provides clear and simple definitions. Fil led with photos and diagrams, this colourful reference book will bring t he language of mathematics to life for primary school students. Also inc luded are many charts, including symbols, abbreviations, shapes, prime n umbers, Roman numerals and fraction and measurement conversion tables.
Book Synopsis Journal of the National Cancer Institute by :
Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 2014 with total page 676 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cancer: New Insights for the Healthcare Professional: 2012 Edition by :
Download or read book Cancer: New Insights for the Healthcare Professional: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-10 with total page 3786 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Cancer. The editors have built Cancer: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cancer in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cancer: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis Targeted Molecular Imaging by : Michael J. Welch
Download or read book Targeted Molecular Imaging written by Michael J. Welch and published by CRC Press. This book was released on 2012-02-24 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeted Molecular Imaging covers the development of novel diagnostic approaches that use an imaging probe and agent to noninvasively visualize cellular processes in normal and disease states. It discusses the concept, development, preclinical studies, and, in many cases, translation to the clinic of targeted imaging agents. The many case studies that form the core of this book deal with the development and translation of non-nuclear probes and radiotracers; other sections address critical topics such as In vitro studies, small animal research, and the application of targeted probes for nuclear, optical and MRI imaging. The chapters use a common format to demonstrate how various investigators approach the comprehensive task of validating a new targeted probe. Targeted Molecular Imaging is a timely resource for a rapidly advancing field, and addresses: Various methods of validating a new targeted probe through examples from human studies with imaging of breast cancer, cardiovascular disease, and neurodegenerative diseases Basic principles, disease models, imaging studies in animals, imaging in initial human studies, and the application of molecular imaging in pharmacy and drug discovery In vitro studies, small animal studies, and targeted radiopharmaceuticals Using these case studies, investigators can generalize and apply the information to their own specific targeted probe. The insights provided by the contributors, experts who have developed these approaches in their own groups, help guide scientists planning to translate imaging agents from the concept stage to clinical application.
Book Synopsis Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors by : Prashant Kesharwani
Download or read book Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors written by Prashant Kesharwani and published by Academic Press. This book was released on 2018-04-20 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors addresses brain anatomy and tumors and the progress and challenges in delivering drugs across the blood brain barrier. Several chapters are devoted to the latest technologies and advances in nanotechnology, along with practical solutions on how to design more effective nanocarriers for drug and gene delivery. This valuable resource prepares readers to develop novel drug delivery systems for the treatment of brain tumors that further promote the latest nanomedical technologies. Addresses the progress and challenges inherent in delivering drugs across the blood brain barrier and offers strategies to maximize effectiveness Draws upon the experience and expertise of international scientists working in the fields of drug delivery and nanomedicine Considers the future possibilities of nanotechnology for delivering nanocarriers that better diagnose and treat brain tumors
Book Synopsis Targeting Signaling Pathways in Solid Tumors Part B by :
Download or read book Targeting Signaling Pathways in Solid Tumors Part B written by and published by Elsevier. This book was released on 2024-07-01 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targetting Signaling Pathways in Solid tumour Part B, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Provides the latest information on cancer research Offers outstanding and original reviews on a range of cancer research topics Serves as an indispensable reference for researchers and students alike
Book Synopsis Targeted Therapies in Oncology by : Giuseppe Giaccone
Download or read book Targeted Therapies in Oncology written by Giuseppe Giaccone and published by CRC Press. This book was released on 2013-10-21 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the last edition of this book, major advances have been made in our understanding of key pathways that control tumor progression. This has led to the development of new anticancer agents that have the ability to block the activity of proteins involved in neoplastic cell development and proliferation. Targeted Therapies in Oncology, Second Edi
Book Synopsis Cells: Advances in Research and Application: 2011 Edition by :
Download or read book Cells: Advances in Research and Application: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 2793 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cells: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Cells. The editors have built Cells: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cells in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cells: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
