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Author : Marion D. Kendall
Publisher : Harwood Academic Pub
ISBN 13 : 9783718649327
Total Pages : 324 pages
Book Rating : 4.6/5 (493 download)
Download or read book T Lymphocyte Differentiation in the Human Thymus written by Marion D. Kendall and published by Harwood Academic Pub. This book was released on 1989 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)
Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author : Jonathan Soboloff
Publisher : CRC Press
ISBN 13 : 149870509X
Total Pages : 258 pages
Book Rating : 4.4/5 (987 download)
Download or read book Signaling Mechanisms Regulating T Cell Diversity and Function written by Jonathan Soboloff and published by CRC Press. This book was released on 2017-03-27 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.
Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Rémy Bosselut
Publisher : Humana
ISBN 13 : 9781493928088
Total Pages : 0 pages
Book Rating : 4.9/5 (28 download)
Download or read book T-Cell Development written by Rémy Bosselut and published by Humana. This book was released on 2015-08-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides simple and accessible experiment protocols to explore thymus biology. T-Cell Development: Methods and Protocols is divided into three parts presenting short reviews on T cell development, analysis strategies, protocols for cell preparation, flow cytometry analyses, and multiple aspects of thymocyte biology. As a volume in the highly successful Methods in Molecular Biology series, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Concise and easy-to-use, T-Cell Development: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Author : Bianca Blom
Publisher :
ISBN 13 : 9789090111001
Total Pages : 184 pages
Book Rating : 4.1/5 (11 download)
Download or read book Control of Early T Cell Differentiation in the Human Thymus written by Bianca Blom and published by . This book was released on 1997 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Amit Awasthi
Publisher : Frontiers Media SA
ISBN 13 : 2889636143
Total Pages : 231 pages
Book Rating : 4.8/5 (896 download)
Download or read book T Cell Differentiation and Function in Tissue Inflammation written by Amit Awasthi and published by Frontiers Media SA. This book was released on 2020-03-11 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Marion D. Kendall
Publisher : CRC Press
ISBN 13 : 9783718651139
Total Pages : 398 pages
Book Rating : 4.6/5 (511 download)
Download or read book The Thymus in Immunotoxicology written by Marion D. Kendall and published by CRC Press. This book was released on 1991 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Thymus Update 4" details the sensitivity of the thymus to xenobiotics and their effects on thymocyte development and maturation. It highlights the importance of immunological testing of all envoronmental toxins, such as dioxin, tin compounds and caramel additives, and drugs, such as immunosuppressives, antiviral agents and antihypertensive agents. The effects of trauma are also considered. Part two covers a subject of topical importance: an update on procedures for vascular transplantation of the thymus.
Author : B. Kyewski
Publisher : Springer Science & Business Media
ISBN 13 : 3540277021
Total Pages : 331 pages
Book Rating : 4.5/5 (42 download)
Download or read book CD4+CD25+ Regulatory T Cells: Origin, Function and Therapeutic Potential written by B. Kyewski and published by Springer Science & Business Media. This book was released on 2006-01-09 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: The vertebrate immune system defends the organism against invading pathogens while at the same time being self-tolerant to the body’s own constituents thus preserving its integrity. Multiple mechanisms work in concert to ensure self-tolerance. Apart from purging the T cell repertoire from auto-reactive T cells via negative selection in the thymus dominant tolerance exerted by regulatory T cells plays a major role in tolerance imposition and maintenance. Among the various regulatory/suppressive cells hitherto described, CD4+CD25+ regulatory T cells (Treg) and interleukin-10 producing T regulatory 1 (Tr1) cells have been studied in most detail and are the subject of most articles in this issue. Treg, also called "natural" regulatory T cells, will be traced from their intra-thymic origin to the site of their action in peripheral lymphoid organs and tissues. The repertoire of Treg is clearly biased towards recognition of self-antigens, thereby potentially preventing autoimmune diseases such as gastritis and oophoritis. Regulatory T cells, however also control infections, allergies and tolerance to transplanted tissues and this requires their induction in the periphery under conditions which are not yet fully understood. The concept of dominant tolerance, by far not novel, will offer new insights and hopefully tools for the successful treatment of autoimmune diseases, improved cancer immunotherapy and transplant survival. The fulfillment of these high expectations will, however, require their unambiguous identification and a better understanding of their mode of action.
Author : Gheorghita Isvoranu
Publisher : BoD – Books on Demand
ISBN 13 : 9535133438
Total Pages : 194 pages
Book Rating : 4.5/5 (351 download)
Download or read book Lymphocyte Updates written by Gheorghita Isvoranu and published by BoD – Books on Demand. This book was released on 2017-07-12 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents a synergic effort of an international team of specialists in immunology to expand the scientific achievements in the field of lymphocytes. It offers important and specific updated information to researchers, students, teachers, and medical professionals. Moreover, considering the remarkable dynamics of immunology and immunotherapy, this book "Lymphocyte Updates - Cancer, Autoimmunity, and Infection" aims to represent a significant source of concise scientific data and advancement of knowledge in this field. The chapters offer new insights into the latest scientific progress on lymphocyte roles in protective immunity, as well as their involvement in pathogenesis of various disorders.
Author : Kitty Verhoeckx
Publisher : Springer
ISBN 13 : 3319161040
Total Pages : 341 pages
Book Rating : 4.3/5 (191 download)
Download or read book The Impact of Food Bioactives on Health written by Kitty Verhoeckx and published by Springer. This book was released on 2015-04-29 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Infogest” (Improving Health Properties of Food by Sharing our Knowledge on the Digestive Process) is an EU COST action/network in the domain of Food and Agriculture that will last for 4 years from April 4, 2011. Infogest aims at building an open international network of institutes undertaking multidisciplinary basic research on food digestion gathering scientists from different origins (food scientists, gut physiologists, nutritionists...). The network gathers 70 partners from academia, corresponding to a total of 29 countries. The three main scientific goals are: Identify the beneficial food components released in the gut during digestion; Support the effect of beneficial food components on human health; Promote harmonization of currently used digestion models Infogest meetings highlighted the need for a publication that would provide researchers with an insight into the advantages and disadvantages associated with the use of respective in vitro and ex vivo assays to evaluate the effects of foods and food bioactives on health. Such assays are particularly important in situations where a large number of foods/bioactives need to be screened rapidly and in a cost effective manner in order to ultimately identify lead foods/bioactives that can be the subject of in vivo assays. The book is an asset to researchers wishing to study the health benefits of their foods and food bioactives of interest and highlights which in vitro/ex vivo assays are of greatest relevance to their goals, what sort of outputs/data can be generated and, as noted above, highlight the strengths and weaknesses of the various assays. It is also an important resource for undergraduate students in the ‘food and health’ arena.
Author : Larisa Y. Poluektova
Publisher : Springer
ISBN 13 : 1493916556
Total Pages : 536 pages
Book Rating : 4.4/5 (939 download)
Download or read book Humanized Mice for HIV Research written by Larisa Y. Poluektova and published by Springer. This book was released on 2015-02-18 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last several years the field of humanized mice has matured and developed into an essential component of translational research for HIV/AIDS. Humanized mice serve both as vehicles for discovery and as highly sophisticated platforms for biomedical research. In addition, humanized mice have demonstrated outstanding potential for the investigation of critical aspects of the infection and pathogenesis of the hepatitis and herpes viruses, as well as highly relevant microbial infections such as tuberculosis and malaria. Humanized Mice for HIV Research provides a comprehensive presentation of the history, evolution, applications, and current state of the art of this unique animal model. An expansion of twelve review articles that were published in Humanized Mice by Springer in 2008 (Eds: Nomura T, Watanabe T, Habu S), this book expertly captures the outstanding progress that has been made in the development, improvement, implementation, and validation of humanized mouse models. The first two parts of this book cover the basics of human-to-mouse xenotransplantation biology, and provide critical information about human immune cell development and function based on individual models created from different immunodeficient strains of mice. The third and fourth parts investigate HIV-1 biology, including different routes of transmission, prevention, treatment, pathogenesis, and the development of adaptive immunity in humanized mice. The fifth part shows the broad applicability of humanized mice for therapeutic development, from long-acting antiretroviral combinations to genetic manipulations with human cells and cell-based approaches. The sixth part includes liver tissue engineering and the expansion of humanized mice for many other human cell-tropic pathogens.
Author : Jonathan Soboloff
Publisher : CRC Press
ISBN 13 : 131535442X
Total Pages : 509 pages
Book Rating : 4.3/5 (153 download)
Download or read book Signaling Mechanisms Regulating T Cell Diversity and Function written by Jonathan Soboloff and published by CRC Press. This book was released on 2017-03-27 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.
Author : Tomohiro Kurosaki
Publisher : Springer
ISBN 13 : 3319261339
Total Pages : 233 pages
Book Rating : 4.3/5 (192 download)
Download or read book B Cell Receptor Signaling written by Tomohiro Kurosaki and published by Springer. This book was released on 2015-12-26 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton’s Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.
Author : Robert Oosterom
Publisher :
ISBN 13 :
Total Pages : 190 pages
Book Rating : 4.:/5 (33 download)
Download or read book Humoral Function of the Human Thymus written by Robert Oosterom and published by . This book was released on 1980 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Nima Rezaei
Publisher : BoD – Books on Demand
ISBN 13 : 1789851335
Total Pages : 145 pages
Book Rating : 4.7/5 (898 download)
Download or read book Thymus written by Nima Rezaei and published by BoD – Books on Demand. This book was released on 2020-01-29 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: The thymus gland is highly valuable, due to its functions as a part of the neuroendocrine system as well as its actions to provide a primary lymphoid microenvironment that efficiently carries T-cell differentiation and selection. This book begins with an introduction and explanation of the development of the thymus. Subsequent chapters examine a range of conditions - including environmental pollution, congenital anomalies, autoimmune diseases, and malignancies - that threaten the function and development of the thymus. The information presented herein is useful for a wide range of readers across a variety of specialties.
Author : Marita Bosticardo
Publisher : Frontiers Media SA
ISBN 13 : 2889714497
Total Pages : 177 pages
Book Rating : 4.8/5 (897 download)
Download or read book Thymic Epithelial Cells: New Insights into the Essential Driving Force of T-Cell Differentiation written by Marita Bosticardo and published by Frontiers Media SA. This book was released on 2021-09-30 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt:
