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American Trypanosomiasis

Author : Jenny Telleria
Publisher : Elsevier
ISBN 13 : 0123848776
Total Pages : 871 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis American Trypanosomiasis by : Jenny Telleria

Download or read book American Trypanosomiasis written by Jenny Telleria and published by Elsevier. This book was released on 2010-09-03 with total page 871 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chagas disease causes severe socioeconomic impact and a high medical cost in Latin America. WHO and the World Bank consider Chagas disease as the fourth most transmittable disease to have a major impact on public health in Latin America: 120 million persons are potentially exposed, 16 to 18 million of whom are presently infected, causing 45,000 to 50,000 deaths per year. It has been calculated that approximately 2.4 million potential working years are lost because of incapacity and mortality due to the disease, for an annual cost estimated at 20 billion Euros. American Trypanosomiasis provides a comprehensive overview of Chagas disease and discusses the latest discoveries concerning the three elements that compose the transmission chain of the disease: The host: human and mammalian reservoirs The insect vectors: domestic and sylvatic vectors The causative parasite: Trypanosoma cruzi Informs and updates on all the latest developments in the field Contributions from leading authorities and industry experts

Chagas Disease

Author : Jaime Marcelo Altcheh
Publisher : Springer Nature
ISBN 13 : 3030000540
Total Pages : 356 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Chagas Disease by : Jaime Marcelo Altcheh

Download or read book Chagas Disease written by Jaime Marcelo Altcheh and published by Springer Nature. This book was released on 2019-09-09 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chagas disease is a potentially life threatening condition that was historically mainly endemic to Latin America. Over the last decade, however, the disease has spread to and is increasingly prevalent in other continents such as North America and Europe, with an estimated 7 million people infected worldwide. It is primarily transmitted by insect vectors that carry the parasite Trypanosoma cruzi, the disease agent. In areas where there is vector control and in non-endemic countries, it is mainly transmitted via congenital infection. Cardiac and gastrointestinal complications are common in untreated individuals. This book offers a comprehensive overview of Chagas disease, including its vectorial and congenital transmission, and molecular diagnosis, which is essential for screening, and developing and providing timely, effective anti-trypanosomal treatment. Written by experts working with infected patients on a daily basis, it discusses the pathogenesis of congenital, cardiac, gastrointestinal and oral Chagas disease, as well as its treatment and the pharmacological aspects of drug development in this area. Chapter "Chagas Disease Treatment Efficacy Biomarkers: Myths and Realities" is available open access under a via link.springer.com.

Control of Chagas Disease

Author : World Health Organization
Publisher : World Health Organization
ISBN 13 : 9241209054
Total Pages : 120 pages
Book Rating : 4.2/5 (412 download)

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Book Synopsis Control of Chagas Disease by : World Health Organization

Download or read book Control of Chagas Disease written by World Health Organization and published by World Health Organization. This book was released on 2002-05 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report of a WHO Expert Committee reviews current knowledge of Chagas disease and its pathogenesis discusses the causative parasite the triatomine vectors and the natural reservoirs of infection and considers the epidemiology and incidence trends of the disease. Prevention and control strategies are described as are the various formal initiatives for interruption of disease transmission. The report concludes by identifying priorities for research and offering guidance for the planning implementation and strengthening of national control programmes. ... this book makes an extremely valuable contribution toward understanding Chagas disease and promoting solid prevention and control efforts. It will no doubt be an important addition to the library of anyone student and expert alike with interests in Chagas disease. The authors are to be congratulated on the completion of a work of excellence - an extremely difficult endeavour at a time when our knowledge of vectors parasites and methodologies is expanding so rapidly. - Transactions of the Royal Society of Tropical Medicine and Hygiene

CURRENT Medical Diagnosis and Treatment 2021

Author : Maxine A. Papadakis
Publisher : McGraw Hill Professional
ISBN 13 : 1260469875
Total Pages : 1984 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis CURRENT Medical Diagnosis and Treatment 2021 by : Maxine A. Papadakis

Download or read book CURRENT Medical Diagnosis and Treatment 2021 written by Maxine A. Papadakis and published by McGraw Hill Professional. This book was released on 2020-09-09 with total page 1984 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now includes a “Year in Review” highlighting over 180 recent medical advances since the last edition! Doody's Core Titles for 2021! For 60 years, CURRENT Medical Diagnosis and Treatment—the flagship volume of the renowned Lange medical series—has been delivering the authoritative information students, residents, and clinicians need to build their medical knowledge, expertise, and confidence. Covering the latest clinical developments in all facets of medicine and fully focused on bedside clinical issues, this new edition provides completely the latest guidelines, reference, drug prices, approved drugs, and evidence-based coverage of more than 1,000 diseases and disorders—all formatted to enable you to find the answers you need quickly and effortlessly. This landmark guide covers inpatient and outpatient care, focusing on the diagnostic tools relevant to daily practice, and reviews all primary care topics, including gynecology/obstetrics, dermatology, ophthalmology, geriatrics, preventive medicine, psychiatry, and neurology. Now includes a “year in review” feature highlighting what’s new in CMDT! Includes essentials of diagnosis for most diseases/disorders Hundreds of quick-access drug treatment tables with indexed trade names Diagnostic and treatment algorithms present important information in an at-a-glance style Up-to-date references provide peer-reviewed, evidence-based information Seven bonus chapters available online to all book purchasers, featuring expanded content and annual review of advances in HIV treatment and critical information on emerging viral infections

Blood Donor Counselling

Author : World Health Organization
Publisher :
ISBN 13 : 9789241548557
Total Pages : 114 pages
Book Rating : 4.5/5 (485 download)

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Book Synopsis Blood Donor Counselling by : World Health Organization

Download or read book Blood Donor Counselling written by World Health Organization and published by . This book was released on 2016-06-24 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Individuals who donate their blood provide a unique and precious gift in an act of human solidarity. In order to donate blood, prospective donors should be in good health and free from any infections that can be transmitted through transfusion. Most blood donors perceive themselves to be healthy, but some are unsuitable to donate blood due to the potential risk of compromising or worsening their own health or the risk of transmission of infections to patients. Blood transfusion services (BTS) have a duty of care towards blood donors as well as to the recipients of transfusion. This duty of care extends to prospective donors who are deferred from donation--whether on a temporary or permanent basis--as well as those who donate blood and are subsequently found to have unusual or abnormal test results. BTS have a responsibility to confirm test results and provide information, counseling and support to enable these individuals to understand and respond to unexpected information about their health or risk status. Counseling is part of the spectrum of care that a BTS should be able to provide to blood donors--including referral to medical practitioners or specialist clinical services. Pre-donation counseling was recognized as one element of the strategy to reduce and, if possible, prevent the donation of blood by individuals who might be at risk for HIV and other TTI including hepatitis B and C viruses as well as to inform the donor of the donation process and testing of blood for HIV. Post-donation counseling was acknowledged to be a necessary element of donor management as an adjunct to informing donors of unusual or abnormal test results. Blood donor counseling by trained specialist staff is now considered to be a key component of the blood system in most countries with a well-developed blood transfusion service. It may be required at a number of stages in the blood donation process or following blood screening and should be available at any point at which the BTS has an interface with donors. In many countries, however, blood donor counseling is not yet available in a structured way. Blood Donor Counselling: Implementation Guidelines has therefore been developed to provide guidance to blood transfusion services that have not yet established donor counseling programs.

The Travel and Tropical Medicine Manual E-Book

Author : Christopher A. Sanford
Publisher : Elsevier Health Sciences
ISBN 13 : 0323417426
Total Pages : 682 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis The Travel and Tropical Medicine Manual E-Book by : Christopher A. Sanford

Download or read book The Travel and Tropical Medicine Manual E-Book written by Christopher A. Sanford and published by Elsevier Health Sciences. This book was released on 2016-08-07 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prevent, evaluate, and manage diseases that can be acquired in tropical environments and foreign countries with The Travel and Tropical Medicine Manual. This pragmatic resource equips medical providers with the knowledge they need to offer effective aid, covering key topics in pre- and post-travel medicine, caring for immigrants and refugees, and working in low-resource settings. It's also the perfect source for travelers seeking quick, easy access to the latest travel medicine information. Dynamic images illustrate key concepts for an enhanced visual understanding. Evidence-based treatment recommendations enable you to manage diseases confidently. This eBook allows you to search all of the text, figures, images, and references from the book on a variety of devices. Highlights new evidence and content surrounding mental health and traveling. Covers emerging hot topics such as Ebola virus disease, viral hemorrhagic fevers, the role of point-of-care testing in travel medicine, and antibiotic-resistant bacteria in returning travelers and students traveling abroad. Includes an enhanced drug appendix in the back of the book.

American Trypanosomiasis

Author : Kevin M. Tyler
Publisher : Springer Science & Business Media
ISBN 13 : 1441992065
Total Pages : 166 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis American Trypanosomiasis by : Kevin M. Tyler

Download or read book American Trypanosomiasis written by Kevin M. Tyler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: American trypanosomiasis, or Chagas disease, is caused by the protozoan parasite, Trypanosoma cruzi. Sixteen to eighteen million people are currently infected with this organism, and 45,000 deaths are attributed to the disease each year. Infection with T. cruzi is life-long, and 10-30% of persons who harbor the parasite chronically develop cardiac and gastrointestinal problems associated with the parasitosis. Although major progress has been made in recent years in reducing vector-borne and transfusion-associated transmission of T. cruzi, the burden of disability and death in persons chronically infected with the organism continues to be enormous. Eight to ten million persons born in countries in which Chagas disease is endemic currently reside in the United States, and epidemiologic and census data suggest that 50,000-100,000 are chronically infected with T. cruzi. The presence of these infected persons poses a risk of transmission of the parasite in the USA through blood transfusion and organ transplantation and several such cases have now been documented. American Trypanosomiasis, volume seven of World Class Parasites is written for students of tropical medicine, parasitology and public health, for researchers and practitioners alike who wish to bring themselves abreast of the status quo with respect to this disease. It is intended to supplement formal textbooks, in order to broaden and illuminate current areas of scientific and public health concern. Uniquely for T. cruzi, this book addresses parasite, vector and host biology, the pathogenesis of Chagas disease and current and prospective therapeutics and control strategies in a single volume.

The Biology of Trypanosomes

Author : Leslie Hudson
Publisher : Springer Science & Business Media
ISBN 13 : 3642705383
Total Pages : 189 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis The Biology of Trypanosomes by : Leslie Hudson

Download or read book The Biology of Trypanosomes written by Leslie Hudson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: African and South American trypanosomiases are notable features of clinical and veterinary practice in their respective endemic areas and, as such, are of considerable economic importance. Scientifically, however, their importance ex tends beyond their clinical significance, as the trypano somes are intriguing and easily manipulated models for the study of the control of gene expression, membrane chemistry, proliferation and differentiation. It is clear from the scientific press that the rate of advance has "hotted" up in these areas of trypanosome research over the past 5 years and so a single-topic volume within the scope of the present series seemed timely. As ever, the final admix ture of review topics was a compromise between what was appropriate and what was available - fortunately with the former in vast excess. I should like to highlight two omissions, made for en tirely different reasons. The first is a detailed treatment of the molecular biology of the variant surface glycopro teins of the African trypanosomes (in particular Trypano soma brucei and T. equiperdum). This topic has been the subject of several reviews, for example, BORST and CROSS (1982)1 and TURNER (1982)2, and so was excluded from the present volume. The second omission is a review of the first-class work on genetic recombination from the group of Dr. Leo Jenni at the Schweizerisches Tropeninsti tut, Basel. This group has used isoenzyme markers to show that T.

Natural Remedies in the Fight Against Parasites

Author : Hanem Khater
Publisher : BoD – Books on Demand
ISBN 13 : 953513289X
Total Pages : 250 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Natural Remedies in the Fight Against Parasites by : Hanem Khater

Download or read book Natural Remedies in the Fight Against Parasites written by Hanem Khater and published by BoD – Books on Demand. This book was released on 2017-07-12 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book emphasizes past and current research efforts about principles of natural control of major parasites affecting humans, animals, and crops. Each chapter is a complete and integrated subject that presents a problem and confers on the safe alternatives to chemicals. This book discusses and updates information about three major topics of natural remedies. The first topic is represented in a chapter outlining important information on biological control of parasites, the second topic is represented in three chapters dealing with botanicals as promising antiparasitic agents, and the last four chapters deal with miscellaneous control strategies against parasites. This easily readable book is designed precisely for students as well as professors linked with the field of parasitic control. We enhanced words with breathing areas in the form of graphical abstracts, figures, photographs, and tables.

Unravelling T. cruzi Biology

Author : Nobuko Yoshida
Publisher : Frontiers Media SA
ISBN 13 : 2889660133
Total Pages : 236 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Unravelling T. cruzi Biology by : Nobuko Yoshida

Download or read book Unravelling T. cruzi Biology written by Nobuko Yoshida and published by Frontiers Media SA. This book was released on 2020-09-23 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Human Emerging and Re-emerging Infections, 2 Volume Set

Author : Sunit Kumar Singh
Publisher : Wiley-Blackwell
ISBN 13 : 9781118644713
Total Pages : 0 pages
Book Rating : 4.6/5 (447 download)

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Book Synopsis Human Emerging and Re-emerging Infections, 2 Volume Set by : Sunit Kumar Singh

Download or read book Human Emerging and Re-emerging Infections, 2 Volume Set written by Sunit Kumar Singh and published by Wiley-Blackwell. This book was released on 2016-01-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emerging and re-emerging pathogens pose several challenges to diagnosis, treatment, and public health surveillance, primarily because pathogen identification is a difficult and time-consuming process due to the “novel” nature of the agent. Proper identification requires a wide array of techniques, but the significance of these diagnostics is anticipated to increase with advances in newer molecular and nanobiotechnological interventions and health information technology. Human Emerging and Re-emerging Infections covers the epidemiology, pathogenesis, diagnostics, clinical features, and public health risks posed by new viral and microbial infections. The book includes detailed coverage on the molecular mechanisms of pathogenesis, development of various diagnostic tools, diagnostic assays and their limitations, key research priorities, and new technologies in infection diagnostics. Volume 1 addresses viral and parasitic infections, while volume 2 delves into bacterial and mycotic infections. Human Emerging and Re-emerging Infections is an invaluable resource for researchers in parasitologists, microbiology, Immunology, neurology and virology, as well as clinicians and students interested in understanding the current knowledge and future directions of infectious diseases.

Trypanosoma cruzi as a Foodborne Pathogen

Author : Belkisyolé de Noya
Publisher : Springer
ISBN 13 : 3319234102
Total Pages : 101 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Trypanosoma cruzi as a Foodborne Pathogen by : Belkisyolé de Noya

Download or read book Trypanosoma cruzi as a Foodborne Pathogen written by Belkisyolé de Noya and published by Springer. This book was released on 2015-10-29 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Brief provides a comprehensive overview of Trypanosoma cruzi, a parasite that is traditionally considered as exclusively vectorborne, but can be foodborne, and may lead to outbreaks of Chagas disease in consumers. The characteristics of Trypanosoma cruzi and the clinical effects of the disease are covered, including documented outbreaks, regional patterns, and epidemiology. The various transmission routes are outlined, but with specific focus on foodborne transmission. A major emphasis of this text is contamination of fruit juices with Trypanosoma cruzi in, a transmission vehicle with increasing significance in the spread of this parasite. Also outlined is the difficulty of establishing a protocol for detection in food samples. Results on survival of Trypanosoma cruzi in food matrices is considered, as well as current risk assessment procedures and regulations. Different approaches to preventing transmission, including inactivation and decontamination are introduced, but also the importance of targeted educational initiatives, and also with a focus on future detection, prevention, and prevention of contamination of foods with this parasite.

T. cruzi Infection

Author : Karina Andrea Gómez
Publisher : Humana Press
ISBN 13 : 9781493991471
Total Pages : 398 pages
Book Rating : 4.9/5 (914 download)

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Book Synopsis T. cruzi Infection by : Karina Andrea Gómez

Download or read book T. cruzi Infection written by Karina Andrea Gómez and published by Humana Press. This book was released on 2019-05-05 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides detailed descriptions on cutting-edge experimental methods to assess the multiple and complex interactions between T. cruzi and its host. Chapters detail a series of methods and protocols, ranging from rather classical biochemical/genetic approaches to modern, powerful and high-throughput ‘-omics’ technologies, to tackle this issue, as well as novel techniques to improve treatment and clinical evaluation of Chagasic patients. Genome-wide mining strategies aimed at identifying potential parasite antigens and vaccine candidates and an overview on the challenges and milestones encountered during T. cruzi genome assembly are also included. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, T. cruzi Infection: Methods and Protocols aims to provide students, researchers, and clinicians who are interested in the study of Chagas disease an indispensable source of information.

Internal Medicine

Author : Jarrah Ali Al-Tubaikh
Publisher : Springer
ISBN 13 : 3319397478
Total Pages : 597 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Internal Medicine by : Jarrah Ali Al-Tubaikh

Download or read book Internal Medicine written by Jarrah Ali Al-Tubaikh and published by Springer. This book was released on 2016-11-14 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: This very well-received book, now in its second edition, equips the radiologist with the information needed in order to diagnose internal medicine disorders and their complications from the radiological perspective. It offers an easy-to-consult tool that documents the most common and most important radiological signs of a wide range of diseases, across diverse specialties, with the aid of an excellent gallery of images and illustrations. Compared with the first edition, numerous additions and updates have been made, with coverage of additional disorders and inclusion of many new images. Entirely new chapters focus on occupational medicine and toxicology imaging, chiropractic medicine, and energy and quantum medicine. Internal Medicine – An Illustrated Radiological Guide puts the radiologist in the internal medicine physician’s shoes. It teaches radiologists how to think in terms of disease progression and complications, explains where to look for and to image these complications, and identifies the best modalities for reaching a diagnosis. It will also benefit internal medicine physicians by clarifying the help that radiology can offer them and assisting in the choice of investigation for diagnostic confirmation.

Molecular Mechanisms of Parasite Invasion

Author : Barbara A. Burleigh
Publisher : Springer Science & Business Media
ISBN 13 : 0387782672
Total Pages : 255 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Molecular Mechanisms of Parasite Invasion by : Barbara A. Burleigh

Download or read book Molecular Mechanisms of Parasite Invasion written by Barbara A. Burleigh and published by Springer Science & Business Media. This book was released on 2008-12-05 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: All of the parasitic organisms highlighted in this new book represent medically important human pathogens that contribute significantly to the global burden of disease. As such there is intense interest in understanding the molecular basis of infection by these pathogens—not only with regard to their clinical relevance but also the fascinating biology they reveal. For most of the parasites discussed here the ability to penetrate biological barriers and/or to establish intracellular residence is critical to survival of the pathogen in the mammalian hosts. For other parasites, a tissue invasive phenotype is a key virulence determinant. In the ensuing 18 chapters, select members of this diverse set of protozoan parasites, as well as some examples of the extremely reduced fungal parasites classified as Microsporidia, are discussed within the context of the fascinating molecular strategies employed by these organisms to migrate across biological barriers and to establish residence within target host cells.

Netter's Infectious Diseases

Author : Elaine C. Jong
Publisher : Elsevier Health Sciences
ISBN 13 : 0323775969
Total Pages : 643 pages
Book Rating : 4.3/5 (237 download)

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Book Synopsis Netter's Infectious Diseases by : Elaine C. Jong

Download or read book Netter's Infectious Diseases written by Elaine C. Jong and published by Elsevier Health Sciences. This book was released on 2021-03-19 with total page 643 pages. Available in PDF, EPUB and Kindle. Book excerpt: Widely used by students, residents, generalists, and specialists, Netter’s Infectious Diseases, 2nd Edition delivers must-know information on infectious diseases in a highly illustrated, easily accessible format. Concise visual overviews of essential topics provide a convenient, trustworthy way to review the basics of a given infectious disease or issue or to share with patients or staff. Drs. Elaine Jong and Dennis Stevens cover the wide spectrum of illness and disease in this complex field using memorable illustrations by world-renowned artist Frank H. Netter and others, offering a time-saving, authoritative look at infectious disease risk factors, clinical presentations, pathophysiology, and more. Covers major conditions and problems such as vaccine-preventable diseases, drug-resistant staph, community acquired pneumonia, surgical infections, pyelonephritis, viral hepatitis, and sexually transmitted infections—and provides updated approaches to diagnosis, treatment, prevention, and standards of care. Includes new clinical vignettes added to most chapters Provides updated and expanded coverage of emerging infectious diseases such as multidrug resistant tuberculosis (MDR-TB), neuroangiostrongyliasis (rat lungworm disease), Ebola virus, Severe Acute Respiratory Disease (SARS), Middle East Respiratory Syndrome (MERS), Coronavirus Infectious Disease-2019 (COVID-19), and novel influenza viruses including public health concerns. Covers vector-borne diseases including malaria, yellow fever, Zika infections and congenital Zika syndrome, West Nile fever, Lyme disease, tick-borne encephalitis, and Chagas disease plus others. New chapters on travelers’ diarrhea, cholera, and primary amebic meningoencephalitis debut in the section on international travel and outdoor activities. Contains memorable parasite life cycles and unforgettable parasite infection clinical vignettes. Features unparalleled illustrations by Drs. Frank H. Netter, Carlos Machado, and others, as well as radiologic images. Provides 24 printable patient education brochures in the digital ebook.

Biology of Trypanosoma cruzi

Author : Wanderley De Souza
Publisher : BoD – Books on Demand
ISBN 13 : 1839682035
Total Pages : 236 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Biology of Trypanosoma cruzi by : Wanderley De Souza

Download or read book Biology of Trypanosoma cruzi written by Wanderley De Souza and published by BoD – Books on Demand. This book was released on 2019-12-18 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Trypanosoma cruzi, an important zoonotic protozoan that causes Chagas disease, affects at least 8 million people in Latin America. Chagas disease is an important life-long infection in humans that can be divided into distinct clinical stages: the acute phase, where patient symptoms can vary from asymptomatic to severe; the indeterminate form, which is usually asymptomatic; and the chronic phase, where cardiomyopathy and/or digestive megasyndromes appear. In addition to its medical importance, T. cruzi is an interesting biological model for studying processes such as: (1) cell differentiation, where a non-infective stage transforms into an infective one; (2) cell invasion, where the infective stages are able to penetrate into a mammalian host cell, where they multiply several times and thus amplify the infection; and (3) evasion from the immune system, using several mechanisms. This book, with 13 chapters, has been organized in four major sections: 1. "Basic Biology," 2. "Biochemistry and Molecular Biology," 3. "Parasite"Host Cell Interaction," and 4 "Chemotherapy." The chapters include basic biological information on the protozoan lifecycle, including new information on parasite genomics and proteomics. In addition, they analyze the interaction with host cells as well the immune response and evasion, ending with information on experimental chemotherapy against Chagas disease.