"System and Methodology for Receptor-level Fluorescence Imaging During Surgery"

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ISBN 13 :
Total Pages : 400 pages
Book Rating : 4.:/5 (881 download)

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Book Synopsis "System and Methodology for Receptor-level Fluorescence Imaging During Surgery" by : Kristian J. Sexton

Download or read book "System and Methodology for Receptor-level Fluorescence Imaging During Surgery" written by Kristian J. Sexton and published by . This book was released on 2014 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: e"Fluorescence molecular imaging will have an important clinical impact in the area of guided oncology surgery, where emerging technologies are poised to provide the surgeon with real-time molecular information to guide resection, using targeted molecular probes. The development of advanced surgical systems has gone hand in hand with probe development, and both aspects are analyzed in this work. A pulsed-light fluorescence guided surgical (FGS) system has been introduced to enable video rate visible light molecular imaging under normal room light conditions. The concepts behind this system design are presented and performance is compared with a commercial system in both phantom and in vivo animal studies using PpIX fluorescence. The second critical advance in the emergence of these technologies has been the development of targeted near infrared (NIR) probes. A small, engineered three-helix protein was analyzed for imaging of glioma tumors. The blood brain barrier affects delivery of probes and the superior delivery of a smaller targeted protein (anti-EGFR Affibody) as compared to a full sized antibody is shown using a murine model, ex vivo tissue slices and a commercial imaging system. This small targeted probe is examined further for its possible application in FGS using the pulsed light imaging system. A concentration sensitivity analysis to determine the lower bounds on concentration needed for effective imaging is performed with this culminating analysis carried out in a murine orthotopic glioma tumor model."

Fluorescence Imaging for Surgeons

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Publisher : Springer
ISBN 13 : 3319156780
Total Pages : 357 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Fluorescence Imaging for Surgeons by : Fernando D. Dip

Download or read book Fluorescence Imaging for Surgeons written by Fernando D. Dip and published by Springer. This book was released on 2015-07-21 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text presents the experiences of leading researchers and surgeons with different fluorescence methods. Chapters range from basic science of fluorescence to current clinical applications and new horizons. The first few chapters describe the historical evolution and physical principles of fluorescence and provide the foundation for the reader to understand the current scope and limits of its use in surgery. The second section focuses on the clinical applications of intraoperative fluorescence imaging including subsections on fluorescence cholangiography, applications to hepatectomy, lymph node navigation, applications to GI tract and pelvic surgery and identification of cancer tissues. The third section focuses on new frontiers including fluorescence probes, imaging systems and applications to photodynamic therapy. Authored by leaders in the development of fluorescent methods worldwide, Fluorescence Imaging for Surgeons: Concepts and Applications will have an impact on numerous medical specialists including general surgeons, colorectal and minimally-invasive surgeons and surgical oncologists. Researchers will find the book to be an invaluable resource on the latest advances in the utilization of nanoparticles and fluorescent probes.​

WHO Classification of Breast Tumours

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Publisher : International Agency for Research on Cancer
ISBN 13 : 9789283245001
Total Pages : 0 pages
Book Rating : 4.2/5 (45 download)

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Book Synopsis WHO Classification of Breast Tumours by : WHO Classification of Tumours Editorial Board

Download or read book WHO Classification of Breast Tumours written by WHO Classification of Tumours Editorial Board and published by International Agency for Research on Cancer. This book was released on 2019-11-21 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Table of contents : - TNM staging of carcinomas of the breast - 1. Introduction to tumours of the breast - 2. Epithelial tumours of the breast - 3. Fibroepithelial tumours and hamartomas of the breast - 4. Tumours of the nipple - 5. Mesenchymal tumours of the breast - 6. Haematolymphoid tumours of the breast - 7. Tumours of the male breast - 8. Metastases to the breast - 9. Genetic tumours syndromes of the breast.

Fluorescent Imaging

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318022934
Total Pages : 134 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fluorescent Imaging by : N. Kokudo

Download or read book Fluorescent Imaging written by N. Kokudo and published by Karger Medical and Scientific Publishers. This book was released on 2013-09-10 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: Indocyanine green (ICG) fluorescence has been used for imaging purposes for more than half a century; First employed by ophthalmologists for visualizing the retinal artery in the late 1960s, the application of ICG fluorescence imaging has since been continuously expanded. Recently, advances in imaging technologies have led to renewed attention regarding the use of ICG in the field of hepatobiliary surgery, as a new tool for visualizing the biliary tree and liver tumors.

Strategies for Curative Fluorescence-Guided Surgery of Cancer

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Publisher : Academic Press
ISBN 13 : 0128126779
Total Pages : 296 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Strategies for Curative Fluorescence-Guided Surgery of Cancer by : Robert Hoffman

Download or read book Strategies for Curative Fluorescence-Guided Surgery of Cancer written by Robert Hoffman and published by Academic Press. This book was released on 2020-05-27 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Strategies for Curative Fluorescence-Guided Surgery of Cancer is the first book to discuss how fluorescence-guided surgery can be successfully used during surgeries with several tumor types. FGS is one of the most exciting emerging modalities of surgery, especially cancer surgery, as it potentially allows the surgeon to visualize the actual margin of the tumor, thus greatly increasing the possibility of curative resection. The book discusses the applicability of FGS for several types of cancer, such as pancreatic cancer, liver metastasis, soft-tissue sarcoma, glioma, melanoma, and breast and lung cancer. This book is a valuable resource for cancer surgeons, cancer researchers and members of several other areas in the biomedical field who are interested in understanding this powerful technique. Presents an overview of fluorescence-guided surgery Explains general strategies for curative fluorescence-guided surgery and their applicability for each major tumor type Discusses the current and future achievements of FGS as a precise technique for cancer surgeries

Visualizing Chemistry

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Publisher : National Academies Press
ISBN 13 : 030916463X
Total Pages : 222 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Visualizing Chemistry by : National Research Council

Download or read book Visualizing Chemistry written by National Research Council and published by National Academies Press. This book was released on 2006-06-01 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists and engineers have long relied on the power of imaging techniques to help see objects invisible to the naked eye, and thus, to advance scientific knowledge. These experts are constantly pushing the limits of technology in pursuit of chemical imagingâ€"the ability to visualize molecular structures and chemical composition in time and space as actual events unfoldâ€"from the smallest dimension of a biological system to the widest expanse of a distant galaxy. Chemical imaging has a variety of applications for almost every facet of our daily lives, ranging from medical diagnosis and treatment to the study and design of material properties in new products. In addition to highlighting advances in chemical imaging that could have the greatest impact on critical problems in science and technology, Visualizing Chemistry reviews the current state of chemical imaging technology, identifies promising future developments and their applications, and suggests a research and educational agenda to enable breakthrough improvements.

Comprehensive Biomedical Physics

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Publisher : Newnes
ISBN 13 : 0444536337
Total Pages : 4052 pages
Book Rating : 4.4/5 (445 download)

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Book Synopsis Comprehensive Biomedical Physics by :

Download or read book Comprehensive Biomedical Physics written by and published by Newnes. This book was released on 2014-07-25 with total page 4052 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Biomedical Physics, Ten Volume Set is a new reference work that provides the first point of entry to the literature for all scientists interested in biomedical physics. It is of particularly use for graduate and postgraduate students in the areas of medical biophysics. This Work is indispensable to all serious readers in this interdisciplinary area where physics is applied in medicine and biology. Written by leading scientists who have evaluated and summarized the most important methods, principles, technologies and data within the field, Comprehensive Biomedical Physics is a vital addition to the reference libraries of those working within the areas of medical imaging, radiation sources, detectors, biology, safety and therapy, physiology, and pharmacology as well as in the treatment of different clinical conditions and bioinformatics. This Work will be valuable to students working in all aspect of medical biophysics, including medical imaging and biomedical radiation science and therapy, physiology, pharmacology and treatment of clinical conditions and bioinformatics. The most comprehensive work on biomedical physics ever published Covers one of the fastest growing areas in the physical sciences, including interdisciplinary areas ranging from advanced nuclear physics and quantum mechanics through mathematics to molecular biology and medicine Contains 1800 illustrations, all in full color

Radioguided Surgery

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Publisher : Springer Science & Business Media
ISBN 13 : 0387383271
Total Pages : 319 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Radioguided Surgery by : Giuliano Mariani

Download or read book Radioguided Surgery written by Giuliano Mariani and published by Springer Science & Business Media. This book was released on 2010-05-10 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: This multidisciplinary textbook is designed to be the standard on the subject and is geared for use by physicians who are involved in the care and/or diagnosis of cancer patients. Comprehensive coverage is provided on all aspects of radioguided surgery. Practical information is readily accessible and throughout there is an emphasis on improved decision making. Tables present the indications, performance, and interpretation of procedures at a glance. A wealth of illustrations, including a full-color insert, enhances the application of new concepts.

Handbook of Photonics for Biomedical Engineering

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Publisher : Springer
ISBN 13 : 9789400750517
Total Pages : 0 pages
Book Rating : 4.7/5 (55 download)

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Book Synopsis Handbook of Photonics for Biomedical Engineering by : Aaron H.-P. Ho

Download or read book Handbook of Photonics for Biomedical Engineering written by Aaron H.-P. Ho and published by Springer. This book was released on 2016-09-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanophotonics has emerged rapidly into technological mainstream with the advent and maturity of nanotechnology available in photonics and enabled many new exciting applications in the area of biomedical science and engineering that were unimagined even a few years ago with conventional photonic engineering techniques. Handbook of Nanophotonics in Biomedical Engineering is intended to be a reliable resource to a wealth of information on nanophotonics that can inspire readers by detailing emerging and established possibilities of nanophotonics in biomedical science and engineering applications. This comprehensive reference presents not only the basics of nanophotonics but also explores recent experimental and clinical methods used in biomedical and bioengineering research. Each peer-reviewed chapter of this book discusses fundamental aspects and materials/fabrication issues of nanophotonics, as well as applications in interfaces, cell, tissue, animal studies, and clinical engineering. The organization provides quick access to current issues and trends of nanophotonic applications in biomedical engineering. All students and professionals in applied sciences, materials, biomedical engineering, and medical and healthcare industry will find this essential reference book highly useful.

Fluorescence Lifetime Imaging Ophthalmoscopy

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Publisher : Springer
ISBN 13 : 3030228789
Total Pages : 121 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Fluorescence Lifetime Imaging Ophthalmoscopy by : Martin Zinkernagel

Download or read book Fluorescence Lifetime Imaging Ophthalmoscopy written by Martin Zinkernagel and published by Springer. This book was released on 2019-07-29 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the emerging non-invasive imaging technique of Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO). FLIO reveals unique information on retinal diseases, ranging from age-related macular degeneration and vascular diseases to hereditary retinal dystrophies. Fluorescence lifetimes enable the evaluation of disease progression before irreversible structural changes occur. The image acquisition is suitable for diagnostic purposes and follow-up examinations to investigate the natural course of disease, and to monitor the effects of possible therapies. This book fills the gap between available literature and gives state-of-the-art guidance on the principles of the FLIO technique, image acquisition, and data analysis. Written by a team of expert leaders within this field, this book will be relevant for scientists and clinicians with an interest in ophthalmoscopy.

Oral Precancer

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Publisher : John Wiley & Sons
ISBN 13 : 1118346432
Total Pages : 237 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis Oral Precancer by : Peter Thomson

Download or read book Oral Precancer written by Peter Thomson and published by John Wiley & Sons. This book was released on 2012-01-30 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Without early detection, oral cancer is deadly. Protect your patients by applying the latest clinical interventions. Rates of new oral cancer cases continue to increase and mortality rates remain alarmingly high. Oral cancer may be preceded by clinically identifiable precancerous changes in the oral mucosa, which offer a therapeutic window of opportunity to intervene and halt disease progression to carcinoma development. Written and edited by prominent researchers in the field, Oral Precancer: Reviews current scientific research on precancer conditions of the oral cavity providing evidence-based analysis of the nature and behavior of potentially malignant and deforming oral diseases Explains the principles of prevention, diagnosis and management of potentially malignant disorders of the oral cavity Details a practical and reliable interventional treatment strategy to facilitate early diagnosis and effective treatment of both precancer and early invasive carcinoma Contains a chapter devoted to illustrative case histories, high-quality, color, clinical photos, reference sections in each chapter listing relevant review articles, and more From start to finish, Oral Precancer offers undergraduate students, clinicians, and professors an invaluable resource to minimise the morbidity and mortality of this most significant and life threatening of oral conditions.

Imaging and Visualization in The Modern Operating Room

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Publisher : Springer
ISBN 13 : 1493923269
Total Pages : 286 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Imaging and Visualization in The Modern Operating Room by : Yuman Fong

Download or read book Imaging and Visualization in The Modern Operating Room written by Yuman Fong and published by Springer. This book was released on 2015-05-19 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a state of the art overview of tools for guiding surgeons in the modern operating room. The text explains how many modalities in the current armamentarium of radiologic imaging have been brought to the operating room for real time use. It also explains the current use of near infrared, fluorescent, and chemo-luminescent imaging to guide minimally invasive and open surgery to improve outcome. The book is separated into two sections. The first, discusses the biologic principles that underlie novel visualization of normal organs and pathology. The currently available equipment and equipment anticipated in the near future is covered. The second section summarizes current clinical applications of advanced imaging and visualization in the OR. Novel means of visualizing normal anatomic structures such as nerves, bile duct, and vessels that enhance safety of many operations are covered. Novel biologic imaging using radio-labeled and fluorescent-labeled molecular probes that allow identification of inflammation, vascular abnormalities, and cancer are also discussed. Authored by scientists who pioneer research in optics and radiology, tool makers who use this knowledge to make surgical equipment, and surgeons who innovate the field of surgery using these new operative tools, Imaging and Visualization in the Modern Operating Room is a valuable guide for surgeons, residents and fellows entering the field.

Thyroid and Parathyroid Surgery

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Publisher :
ISBN 13 : 9783805589819
Total Pages : 0 pages
Book Rating : 4.5/5 (898 download)

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Book Synopsis Thyroid and Parathyroid Surgery by : D. J. Terris

Download or read book Thyroid and Parathyroid Surgery written by D. J. Terris and published by . This book was released on 2008-11-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thyroid surgery has undergone tremendous transformation in recent years, much of which has been technologically driven. Also the approach to the patient with hyperparathyroidism has similarly evolved to an operation that has little in common with the conventional neck exploration of just a decade ago. Highlights of this issue are contributions by leading experts in the field of thyroid surgery. State-of-the-art reviews on minimally invasive thyroid and parathyroid surgery as well as articles on novel approaches to the management of thyroid cancer are included. Further, new technology in thyroid surgery, the management of the central compartment in thyroid cancer, and intraoperative parathyroid hormone monitoring are discussed. Otolaryngologists and surgeons as well as endocrinologists, pediatric endocrinologists, and oncologists managing thyroid diseases will appreciate this comprehensive and timely update.

Drug Safety Evaluation

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Publisher : John Wiley & Sons
ISBN 13 : 1119755859
Total Pages : 996 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Drug Safety Evaluation by : Shayne Cox Gad

Download or read book Drug Safety Evaluation written by Shayne Cox Gad and published by John Wiley & Sons. This book was released on 2023-01-12 with total page 996 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Safety Evluation Comprehensive and practical guide presenting a roadmap for safety assessment as an integral part of the development of drugs and therapeutics This fourth edition of Drug Safety Evaluation maintains the central objective of presenting an all-inclusive practical guide for those who are responsible for ensuring the safety of drugs and biologics to patients, healthcare providers, those involved in the manufacture of medicinal products, and all those who need to understand how the safety of these products is evaluated and shepherding valuable candidates to market. Individual chapters address specific approaches to evaluation hazards, including problems that are encountered and their solutions. Also covered are the scientific and philosophical bases for evaluation of specific concerns (e.g., carcinogenicity, development toxicity, etc.) to provide both understanding and guidance for approaching the new problems that have come to face both our society and the new challenges they brought. The many changes in regulatory requirements, pharmaceutical development, technology, and the effects of Covid on our society and science have required both extensive revision to every chapter and the addition of four new chapters. Specific sample topics covered in Drug Safety Evaluation include: The drug development process and the global pharmaceutical marketplace and regulation of human pharmaceutical safety Sources of information for consideration in study and program design and in safety evaluation Electronic records, reporting and submission, screens in safety and hazard assessment, and formulations, routes, and dosage regimens Mechanisms and endpoints of drug toxicity, pilot toxicity testing in drug safety evaluation, and repeat dose toxicity Genotoxicity, QSAR tools for drug safety, toxicogenomics, nonrodent animal studies, and developmental and reproductive toxicity testing An appendix which provides an up to date guide to CROs for conducting studies Drug Safety Evaluation was written specifically for the pharmaceutical and biotechnology industries, including scientists, consultants, and academics, to show a utilitarian yet scientifically valid path to the everyday challenges of safety evaluation and the problem solving that is required in drug discovery and development.

Small animal imaging: Technological and methodological advances to improve the translational power

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Publisher : Frontiers Media SA
ISBN 13 : 2832511384
Total Pages : 152 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Small animal imaging: Technological and methodological advances to improve the translational power by : Monique R. Bernsen

Download or read book Small animal imaging: Technological and methodological advances to improve the translational power written by Monique R. Bernsen and published by Frontiers Media SA. This book was released on 2023-01-13 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Small Animal Laparoscopy and Thoracoscopy

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Publisher : John Wiley & Sons
ISBN 13 : 1119666856
Total Pages : 474 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Small Animal Laparoscopy and Thoracoscopy by : Boel A. Fransson

Download or read book Small Animal Laparoscopy and Thoracoscopy written by Boel A. Fransson and published by John Wiley & Sons. This book was released on 2022-03-29 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: The newly revised Second Edition of Small Animal Laparoscopy and Thoracoscopy is a rigorous update of the first book to provide comprehensive and current information about minimally invasive surgery in dogs and cats. With a focus on techniques in rigid endoscopy, the book also includes guidance on additional surgeries outside the abdomen and chest. New chapters describe newly developed surgical techniques, while existing chapters have been thoroughly updated. The authors include detailed stepwise instructions for each procedure, including clinical photographs. Pre-operative considerations, patient positioning, portal placement, and postoperative care are also discussed, with key points of consideration outlined for each surgery. Purchasers of the book will also receive access to a companion website featuring video clips of the fundamental skills and surgical techniques described in the resource. The book also offers: An introduction to laparoscopic suturing and knot tying with accompanying video tutorials A thorough introduction to the equipment used in laparoscopic and thoracoscopic veterinary surgeries, including imaging equipment, surgical instrumentation, energy devices, and stapling equipment Clear explanations of foundational techniques in laparoscopy, including laparoscopic anesthesia, access techniques, contraindications, complications, and conversion Robust descriptions of fundamental techniques in thoracoscopy, including patient positioning, port placement, contraindications, complications, and conversion Discussions of a wide variety of laparoscopic and thoracoscopic surgical procedures Small Animal Laparoscopy and Thoracoscopy is an essential reference for veterinary surgeons, veterinary internal medicine specialists and residents, and small animal general practitioners seeking a one-stop reference for minimally invasive surgery in dogs and cats.

Imaging Dopamine

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Publisher : Cambridge University Press
ISBN 13 : 0521790026
Total Pages : 377 pages
Book Rating : 4.5/5 (217 download)

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Book Synopsis Imaging Dopamine by : Paul Cumming

Download or read book Imaging Dopamine written by Paul Cumming and published by Cambridge University Press. This book was released on 2009-04-02 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: An illustrated biography of the dopamine molecule, with each chapter presenting a specific stage in the biochemical pathway for dopamine.