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Author : Anna Claire Giddens
Publisher :
ISBN 13 :
Total Pages : 188 pages
Book Rating : 4.:/5 (155 download)
Download or read book Synthesis of Substituted Hexahydroazepines Using N-acyliminium Ions written by Anna Claire Giddens and published by . This book was released on 2003 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt:
![Download Synthesis of Substituted 6,6a-dihydroisoindolo [2,1-a]quinolin-11(5H)-ones PDF Online Free](https://books.google.com/books/content/images/frontcover/nmCgzgEACAAJ?fife=w200-h370)
Author : Zainab Admad Al-Jaroudi
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (122 download)
Download or read book Synthesis of Substituted 6,6a-dihydroisoindolo [2,1-a]quinolin-11(5H)-ones written by Zainab Admad Al-Jaroudi and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Fused heterocycles have received significant attention because of their diverse biological and pharmaceutical properties. For example, ()-nuevamine, which is the first known isoindoloisoquinoline alkaloid. Isoindolo[2,1-a]quinoline derivatives have attracted much interest because of their structural similarities with ()-nuevamine. In this study, diverse substituted 6,6a-dihydroisoindolo[2,1-a]quinolin-11(5H)-ones were successfully synthesized from N-aryl-3-hydroxyisoindolinones and substituted acetophenones including alkyl aryl cyclic ketones such as indanone and tetralone in three steps involving Lewis-acid-catalyzed C-C bond formation, NaBH4 reduction, and Lewis-acid-catalyzed intramolecular cyclization. First, 3-substituted-(2-oxo)-2-arylisoindolin-1-ones were obtained from fair to very good yields using Cu(OTf)2. The reaction involved N-acyliminium ion as the electrophile. To the best of our knowledge, acetophenones were used for the first time as nucleophiles for the reactions with N-acyliminium ions. Subsequent NaBH4 reduction afforded the corresponding 3-substituted-(2-hydroxy)-2-arylisoindolin-1-ones in excellent yields. Finally, BF3.OEt2-catalyzed intramolecular cyclization afforded substituted 6,6a-dihydroisoindolo[2,1-a]quinolin-11(5H)-ones from poor to excellent yields. All the products were well characterized by NMR and HRMS techniques. Some of the final products were unambiguously characterized by X-ray diffraction analysis. Pure diastereomers of the final products were obtained by recrystallization. Novel interesting tetracyclic and hexacyclic isoindoloquinolines were achieved by this method. The products have been submitted for biological activity as they have shown close structural resemblance with biologically active natural products.
Author : Maria Antonia Wijdeven
Publisher :
ISBN 13 : 9789090249247
Total Pages : 200 pages
Book Rating : 4.2/5 (492 download)
Download or read book Chemoenzymatic Formation of Hydroxypiperidines written by Maria Antonia Wijdeven and published by . This book was released on 2010 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Laszlo Kurti
Publisher : Elsevier
ISBN 13 : 0080575412
Total Pages : 808 pages
Book Rating : 4.0/5 (85 download)
Download or read book Strategic Applications of Named Reactions in Organic Synthesis written by Laszlo Kurti and published by Elsevier. This book was released on 2005-04-29 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kurti and Czako have produced an indispensable tool for specialists and non-specialists in organic chemistry. This innovative reference work includes 250 organic reactions and their strategic use in the synthesis of complex natural and unnatural products. Reactions are thoroughly discussed in a convenient, two-page layout--using full color. Its comprehensive coverage, superb organization, quality of presentation, and wealth of references, make this a necessity for every organic chemist. * The first reference work on named reactions to present colored schemes for easier understanding* 250 frequently used named reactions are presented in a convenient two-page layout with numerous examples* An opening list of abbreviations includes both structures and chemical names * Contains more than 10,000 references grouped by seminal papers, reviews, modifications, and theoretical works * Appendices list reactions in order of discovery, group by contemporary usage, and provide additional study tools* Extensive index quickly locates information using words found in text and drawings
Author : Yuri Dyakov
Publisher : Elsevier
ISBN 13 : 0080469337
Total Pages : 497 pages
Book Rating : 4.0/5 (84 download)
Download or read book Comprehensive and Molecular Phytopathology written by Yuri Dyakov and published by Elsevier. This book was released on 2007-01-09 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a collection of information on successive steps of molecular ‘dialogue’ between plants and pathogens. It additionally presents data that reflects intrinsic logic of plant-parasite interactions. New findings discussed include: host and non-host resistance, specific and nonspecific elicitors, elicitors and suppressors, and plant and animal immunity. This book enables the reader to understand how to promote or prevent disease development, and allows them to systematize their own ideas of plant-pathogen interactions. * Offers a more extensive scope of the problem as compared to other books in the market* Presents data to allow consideration of host-parasite relationships in dynamics and reveals interrelations between pathogenicity and resistance factors* Discusses beneficial plant-microbe interactions and practical aspects of molecular investigations of plant-parasite relationships* Compares historical study of common and specific features of plant immunity with animal immunity
Author : Shu Kobayashi
Publisher : Springer
ISBN 13 : 3540698019
Total Pages : 311 pages
Book Rating : 4.5/5 (46 download)
Download or read book Lanthanides: Chemistry and Use in Organic Synthesis written by Shu Kobayashi and published by Springer. This book was released on 2003-07-01 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts
Author :
Publisher :
ISBN 13 :
Total Pages : 240 pages
Book Rating : 4.3/5 (91 download)
Download or read book Trends in Organometallic Chemistry written by and published by . This book was released on 1999 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Axel G. Griesbeck
Publisher : CRC Press
ISBN 13 : 1439811814
Total Pages : 943 pages
Book Rating : 4.4/5 (398 download)
Download or read book CRC Handbook of Organic Photochemistry and Photobiology written by Axel G. Griesbeck and published by CRC Press. This book was released on 2012 with total page 943 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title includes research from experts in organic chemistry & many other disciplines. There are sections on new terminology, the usefulness of particular reactions & experimental details.
Author : Roberto Ballini
Publisher : Royal Society of Chemistry
ISBN 13 : 1847559085
Total Pages : 313 pages
Book Rating : 4.8/5 (475 download)
Download or read book Eco-friendly Synthesis of Fine Chemicals written by Roberto Ballini and published by Royal Society of Chemistry. This book was released on 2009 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: During these early years, the chronic toxicological properties of chemicals were often completely unknown and many unwittingly became indispensable tools of the trade. Early pioneers in green chemistry included Trost (who developed the atom economy principle) and Sheldon (who developed the E-Factor). These measures were introduced to encourage the use of more sustainable chemistry and provide some benchmarking data to encourage scientists to aspire to more benign synthesis. Green chemistry is essentially the design of chemical processes and procedures that reduce or eliminate the use, or the generation, of hazardous substances. Green chemistry is a growing area of research and an increasing number of researchers are now involved in this field. The number of publications has dramatically increased and new recognition of advances made is necessary with respect to other research areas.
Author : Christopher S. Foote
Publisher : Springer Science & Business Media
ISBN 13 : 9400708742
Total Pages : 355 pages
Book Rating : 4.4/5 (7 download)
Download or read book Active Oxygen in Chemistry written by Christopher S. Foote and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taking an interdisciplinary approach, this book and its counterpart, Active Oxygen in Biochemistry, explore the active research area of the chemistry and biochemistry of oxygen. Complementary but independent, the two volumes integrate subject areas including medicine, biology, chemistry, engineering, and environmental studies.
Author : Gyula Palyi
Publisher : Elsevier
ISBN 13 : 0080474039
Total Pages : 445 pages
Book Rating : 4.0/5 (84 download)
Download or read book Progress in Biological Chirality written by Gyula Palyi and published by Elsevier. This book was released on 2004-12-13 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following on from Advances in BioChirality, Progress in Biological Chirality provides a unique summary and review of the most recent developments in the field of biochirality. Living organisms use only one enantiomer of chiral molecules in the majority of biologically important processes. The exact origin and mechanisms for this surprising selectivity are not yet known. This book discusses current research aimed at identifying the scientific reasons that may contribute to this phenomenon. Progress in Biological Chirality takes an interdisciplinary approach to this exciting field, covering a wide range of topics, such as, theory, palaeontology and food technology, to name but a few. This book presents findings via a broad spectrum of scientific approaches making it an excellent overview of Biological Chirality, suitable for postgraduate students, practitioners and researchers in the field of chemistry, biochemistry, biology, palaeontology, and food science with an interest in Chirality. This book contains 32 chapters written by Authors, who are leading authorities in the field Presents the most recent research taking place in this highly challenging field Contains both reference material for the specialist and provides an overview for those who are interested in the fundamental problems of biology and chemistry
Author : Nicholas J. Turro
Publisher : University Science Books
ISBN 13 : 9780935702712
Total Pages : 644 pages
Book Rating : 4.7/5 (27 download)
Download or read book Modern Molecular Photochemistry written by Nicholas J. Turro and published by University Science Books. This book was released on 1991 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last two decades the photochemistry of organic molecules has grown into an important and pervasive branch of organic chemistry. In Modern Molecular Photochemistry, the author brings students up to date with the advances in this field - the development of the theory of photoreactions, the utilization of photoreactions in synthetic sequences, and the advancement of powerful laser techniques to study the mechanisms of photoreactions.
Author : George Agrios
Publisher : Elsevier
ISBN 13 : 0323144039
Total Pages : 646 pages
Book Rating : 4.3/5 (231 download)
Download or read book Plant Pathology written by George Agrios and published by Elsevier. This book was released on 2012-12-02 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant Pathology presents information and advances in plant pathology including disease induction and development and disease resistance and control. This book is organized into two major parts encompassing 14 chapters that focus on diseases, pathogenicity, and pathogen variability. The first part of the book deals with general considerations of disease, the disease cycle, parasitism and pathogenicity, and the variability in pathogens. This is followed by a presentation of the mechanisms by which pathogens cause disease and plants resist disease. Core chapters focus on the effects of pathogen-produced enzymes, toxins, growth regulators, and polysaccharides on the structural organization and on the basic physiological processes of photosynthesis, translocation, and respiration. The chapters also discuss the defense mechanisms of the plant. Moreover, this book explains the genetics of host-parasite interaction, effects of environment on disease development, and control. The second part of the book deals with the infectious diseases caused by fungi, bacteria, parasitic higher plants, viruses, and nematodes. This part also looks into the noninfectious diseases caused by environmental factors. The diseases caused by each type of pathogen are discussed comprehensively as a group and are subsequently discussed individually in detail. This book includes diagrams of cycles for each disease to create visual images for better understanding of the disease and message retention. This book is ideal for students with introductory course in plant pathology.
Author : Stephen Hanessian
Publisher :
ISBN 13 :
Total Pages : 291 pages
Book Rating : 4.:/5 (778 download)
Download or read book Total Synthesis of Natural Products written by Stephen Hanessian and published by . This book was released on 1986 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Graham Barrett
Publisher : Springer Science & Business Media
ISBN 13 : 9400948328
Total Pages : 694 pages
Book Rating : 4.4/5 (9 download)
Download or read book Chemistry and Biochemistry of the Amino Acids written by Graham Barrett and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amino acids are featured in course syllabuses and in project and research work over a wide spectrum of subject areas in chemistry and biology. Chemists and biochemists using amino acids have many common needs when they turn to the literature for comprehensive information. Among these common interests, analytical studies, in particular, have undergone rapid development in recent years. All other chemical and biochemical aspects of amino acids - synthesis, properties and reactions, preparation of derivatives for use in peptide synthesis, racemization and other fundamental mechanistic knowledge - have been the subject of vigorous progress. This book offers a thorough treatment of all these developing areas, and is structured in the belief that biochemists, physiologists and others will profit from access to information on topics such as the physical chemistry of amino acid solutions, as well as from thorough coverage of amino acid metabolism, biosynthesis and enzyme inhibition; and that chemists will find relevant material in biological areas as well as in the analysis, synthesis and reactions of amino acids.
Author : Goutam Brahmachari
Publisher : Elsevier
ISBN 13 : 0128097698
Total Pages : 492 pages
Book Rating : 4.1/5 (28 download)
Download or read book Discovery and Development of Neuroprotective Agents from Natural Products written by Goutam Brahmachari and published by Elsevier. This book was released on 2017-05-18 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discovery and Development of Neuroprotective Agents from Natural Products draws together global research on medicinal agents from natural sources as starting points for the design of neuroprotective drugs. From the prediction of promising leads and identification of active agents to the extraction of complex molecules, the book explores a range of important topics to support the development of safer, more economical therapeutics for these increasingly prevalent diseases. Beginning with an overview of current developments in the field, the book goes on to explore the identification, extraction and phytochemistry of such neuroprotective agents as antioxidants, biophenols and naturally occurring anti-inflammatory steroid analogues. Specific natural sources of bioactive agents are reviewed, and the development of these agents into therapeutics for a number of specific neurological disorders, including Alzheimer’s disease, Parkinson’s disease and ischemic brain stroke, are discussed. Combining the expertise of specialists from around the world, this in the Natural Products Drug Discovery series aims to support and encourage researchers in the investigation of natural sources as starting points for the development of standardized, safe and effective neuroprotective drugs. Features chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery Includes comprehensive coverage of cutting-edge research advances in the design of drugs from natural products targeted at different kinds of neurodegenerative diseases Offers a practical review of identification, isolation and extraction techniques to support medicinal chemists in the lab
Author : R. H. Manske
Publisher :
ISBN 13 : 9780124695085
Total Pages : 861 pages
Book Rating : 4.6/5 (95 download)
Download or read book The Alkaloids written by R. H. Manske and published by . This book was released on 1965-08-01 with total page 861 pages. Available in PDF, EPUB and Kindle. Book excerpt:
