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Synthesis Of Novel Amino Acids And 310 And Alpha Helical Alpha Alpha Disubstituted Amino Acid Rich Antimicrobial Peptides
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Book Synopsis Synthesis of Novel Amino Acids and 310- and Alpha-helical Alpha, Alpha-disubstituted Amino Acid Rich Antimicrobial Peptides by : Thomas Scott Yokum
Download or read book Synthesis of Novel Amino Acids and 310- and Alpha-helical Alpha, Alpha-disubstituted Amino Acid Rich Antimicrobial Peptides written by Thomas Scott Yokum and published by . This book was released on 1998 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Methods of Non-α-Amino Acid Synthesis, Second Edition by : Michael Bryant Smith
Download or read book Methods of Non-α-Amino Acid Synthesis, Second Edition written by Michael Bryant Smith and published by CRC Press. This book was released on 2013-10-23 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although less common than α-amino acids, non-α-amino acids—where the amino group is not on the carbon immediately adjacent to the carboxyl group but is attached to another carbon in the chain (for example, the β, γ, δ carbon)—are components of biologically important molecules, are significant in the pharmaceutical industry, and are useful starting materials for many areas of organic chemistry. Since the publication of the first edition of this book nearly 20 years ago, synthetic work devoted to the preparation of non- α-amino acids has expanded greatly. Methods of Non-α-Amino Acid Synthesis, Second Edition has been extensively rewritten and reorganized, providing an up-to-date review of strategies and methods for non-α-amino acid synthesis, particularly those amino acids that are key synthetic intermediates or important compounds in their own right. It focuses on acyclic amino acids of C3–C10, but also aminoalkanoic carboxylic acids, aminoalkenoic acids, and aminoalkynoic acids. The new edition contains many updated references and has a greater emphasis on the biological importance of non-α-amino acids. In addition to an array of synthetic methods, the book offers discussions on why non-α-amino acids are important. The book covers synthetic methods that rely on substituent refunctionalization, the conversion of cyclic precursors to acyclic amino acids, conjugate addition reactions, and enolate anion reactions and condensation reactions that lead to non-α-amino acids. It also examines reactions and strategies that lead to good diastereoselectivity and enantioselectivity during synthesis. A chapter devoted to biologically important amino acids includes separate sections on GABA, GABOB, carnitine, DAVA, statine, and other significant amino acids as well as a new section on peptides and proteins that contain non-α-amino acids. The final chapter addresses aminocyclic and heterocyclic amino acids.
Book Synopsis Synthesis and Conformational Studies of Peptides Containing Novel Alpha,alpha-disubstituted Amino Acids by : Clive E. Spiegler
Download or read book Synthesis and Conformational Studies of Peptides Containing Novel Alpha,alpha-disubstituted Amino Acids written by Clive E. Spiegler and published by . This book was released on 1993 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Methods of Non-a-Amino Acid Synthesis by : Michael Smith
Download or read book Methods of Non-a-Amino Acid Synthesis written by Michael Smith and published by CRC Press. This book was released on 1995-05-17 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work provides a comprehensive overview of, and the most common and useful methods for, the synthesis of non-alpha-amino acids, particularly amino acids that are key synthetic intermediates or important compounds in their own right. Attention is paid to acyclic amino acids C3-C10 including amino alkanoic carboxylic acids, aminoalkenoic acids and aminoalkynoic acids.
Book Synopsis Synthesis of Optically Active Alpha-Amino Acids by : R. M. Williams
Download or read book Synthesis of Optically Active Alpha-Amino Acids written by R. M. Williams and published by Elsevier. This book was released on 2013-10-22 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to review and critically evaluate the best new methods to synthesize alpha-amino acids in optically active form. There is so much new literature on amino acid synthesis that the experimentalist will undoubtedly have difficulty in selecting the most appropriate methodology for constructing the amino acid of immediate interest. This book is a guide for steering the scientist through the maze of existing reports on the subject and contains the most up-to-date critical reviews of methods of asymmetric synthesis of amino acids. In areas that are relatively new conceptually and less studied experimentally, an effort has been made to review the most salient works with an eye towards future development. Over 330 schemes and figures are presented with references for rapid visual retrieval of information. The book will be of great value to academic and industrial organic research chemists, especially those concerned with medicinal and agricultural chemistry, as well as to graduate and post graduate students, biochemists and biologists.
Book Synopsis The Synthesis of Labeled Alpha Amino Acids by : James C. Reid
Download or read book The Synthesis of Labeled Alpha Amino Acids written by James C. Reid and published by . This book was released on 1949 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis of Branched Α-[alpha-] and Β-amino[beta-amino] Acids Using C-nucleophile Additions to Imines and Nitrones by : Alevtina Baskakova
Download or read book Synthesis of Branched Α-[alpha-] and Β-amino[beta-amino] Acids Using C-nucleophile Additions to Imines and Nitrones written by Alevtina Baskakova and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Artificial peptides, containing alpha- and/or beta-amino acids with bulky substituents, can potentially possess some unusual properties, for example, decreased conformational ability or formation of stable secondary structures. Therefore, the preparation of such unnatural amino acids is of high interest. In this thesis, a route to enantiomerically pure 1-adamantylglycine was developed. The crucial step was the highly stereoselective addition of adamantylmagnesium bromide to the C=N bond of 2,3-O-cyclohexylidene-D-glyceraldehyde N-benzylnitrone effected in the presence of Lewis acid. Finally, 1-adamantylglycine was synthesized in 28 % yield over 6 steps. The routes to 9-aminofluorenylacetic and beta-aminobeta, beta-diphenylpropionic acids were proposed and they consist in the addition of allyl Grignard reagents to imines with various protecting groups, followed by oxidative transformation of the allyl group. Also some procedures for the preparation of 3,3-disubstituted 4-azetidinones, direct precursors of the corresponding beta-branched beta-amino acids, have been investigated.
Book Synopsis Amino Acid and Peptide Synthesis by : John Jones
Download or read book Amino Acid and Peptide Synthesis written by John Jones and published by Oxford University Press, USA. This book was released on 1992 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: The principal methods for the synthesis of amino acids and peptides are outlined in this concise introduction. With its emphasis on chemical principles and strategies, the book should be of value to all undergraduate chemistry students.
Book Synopsis Synthesis and Conformational Studies of Peptides Containing Novel Α,α-disubstituted Amino Acids by : Clive Edward Spiegler
Download or read book Synthesis and Conformational Studies of Peptides Containing Novel Α,α-disubstituted Amino Acids written by Clive Edward Spiegler and published by . This book was released on 1993 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies on Chemical Synthesis of Peptides: Efficient Synthetic Methods for β-Amino Acids, Azides, Amino Acid Hydroxamates and Esters by : Vasanthakumar Ganga Ramu
Download or read book Studies on Chemical Synthesis of Peptides: Efficient Synthetic Methods for β-Amino Acids, Azides, Amino Acid Hydroxamates and Esters written by Vasanthakumar Ganga Ramu and published by GRIN Verlag. This book was released on 2011-10-17 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Doctoral Thesis / Dissertation from the year 2004 in the subject Chemistry - Organic Chemistry, Bangalore University / Central College (Department of Studies in Chemistry), language: English, abstract: The importance of ß-amino acids has been focused, particularly in the past few decades. They are found as components of many biologically active peptidic and nonpeptidic natural products with antibiotic, antifungal, cytotoxic, and other pharmacological properties. ß-Amino acids are produced in humans, animals, microorganisms, marine organisms, and plants either in free state or as part of a peptide or depsipeptide. The importance of nonpeptidic ß-amino acids has been nfocused particularly on the ß-lactam antibiotics, since naturally occurring penicillin derivatives have been discovered as broad antibiotic active agents. Over the years, a large number of these compounds have been prepared and tested, and a variety of new ß-lactam ring systems have been introduced such as cephems, cephalosporins, oxacephems, penems, carbapenems, oxapenams as well as monocyclic and polycyclic ring systems. ß-Amino acids have been known to play an important role in primary and secondary metabolism also. [...]
Book Synopsis Dissertation Abstracts International by :
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2001 with total page 820 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies on Chemical Synthesis of Peptides by : Vasanthakumar Ganga Ramu
Download or read book Studies on Chemical Synthesis of Peptides written by Vasanthakumar Ganga Ramu and published by GRIN Verlag. This book was released on 2011-10-28 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Doctoral Thesis / Dissertation from the year 2004 in the subject Chemistry - Organic Chemistry, Bangalore University / Central College (Department of Studies in Chemistry), language: English, abstract: The importance of ß-amino acids has been focused, particularly in the past few decades. They are found as components of many biologically active peptidic and nonpeptidic natural products with antibiotic, antifungal, cytotoxic, and other pharmacological properties. ß-Amino acids are produced in humans, animals, microorganisms, marine organisms, and plants either in free state or as part of a peptide or depsipeptide. The importance of nonpeptidic ß-amino acids has been nfocused particularly on the ß-lactam antibiotics, since naturally occurring penicillin derivatives have been discovered as broad antibiotic active agents. Over the years, a large number of these compounds have been prepared and tested, and a variety of new ß-lactam ring systems have been introduced such as cephems, cephalosporins, oxacephems, penems, carbapenems, oxapenams as well as monocyclic and polycyclic ring systems. ß-Amino acids have been known to play an important role in primary and secondary metabolism also. [...]
Book Synopsis Synthesis of Optically Active [alpha]-amino Acids by : Robert Michael Williams
Download or read book Synthesis of Optically Active [alpha]-amino Acids written by Robert Michael Williams and published by Pergamon. This book was released on 1989 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to review and critically evaluate the best new methods to synthesize alpha-amino acids in optically active form. There is so much new literature on amino acid synthesis that the experimentalist will undoubtedly have difficulty in selecting the most appropriate methodology for constructing the amino acid of immediate interest. This book is a guide for steering the scientist through the maze of existing reports on the subject and contains the most up-to-date critical reviews of methods of asymmetric synthesis of amino acids. In areas that are relatively new conceptually and less studied experimentally, an effort has been made to review the most salient works with an eye towards future development. Over 330 schemes and figures are presented with references for rapid visual retrieval of information. The book will be of great value to academic and industrial organic research chemists, especially those concerned with medicinal and agricultural chemistry, as well as to graduate and post graduate students, biochemists and biologists.
Book Synopsis Design, Synthesis, and Conformational Studies of Peptides Containing Alpha, Alpha-disubstituted Amino Acids by : Jia Wang
Download or read book Design, Synthesis, and Conformational Studies of Peptides Containing Alpha, Alpha-disubstituted Amino Acids written by Jia Wang and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis of Unusual Alpha-amino Acids and Study of the Effect of Their Incorporation Into Antimicrobial Peptides by : Abdellatif El Marrouni El Ghazaoui
Download or read book Synthesis of Unusual Alpha-amino Acids and Study of the Effect of Their Incorporation Into Antimicrobial Peptides written by Abdellatif El Marrouni El Ghazaoui and published by . This book was released on 2012 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Alpha , Alpha -disubstituted- Alpha -amino Acids as Building Blocks for Peptide Synthesis by : Sarah Elizabeth Skerratt
Download or read book Alpha , Alpha -disubstituted- Alpha -amino Acids as Building Blocks for Peptide Synthesis written by Sarah Elizabeth Skerratt and published by . This book was released on 2002 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis of Novel Trifluoroethylated [alpha]-amino Acids and Peptides by : Changqing Lu
Download or read book Synthesis of Novel Trifluoroethylated [alpha]-amino Acids and Peptides written by Changqing Lu and published by . This book was released on 2005 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt:
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