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Synthesis Of New Beta Amino Acids And Novel Beta Peptides And Structural Investigations
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Book Synopsis Synthesis of New [beta]-amino Acids and Novel [beta]-peptides, and Structural Investigations by : Gérald Patrick Joseph Jean Louis Lelais
Download or read book Synthesis of New [beta]-amino Acids and Novel [beta]-peptides, and Structural Investigations written by Gérald Patrick Joseph Jean Louis Lelais and published by . This book was released on 2004 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis of New [beta]-amino Acids and Novel [beta]-peptides, and Structural Investigations by : Gérald Patrick Joseph Jean Louis Lelais
Download or read book Synthesis of New [beta]-amino Acids and Novel [beta]-peptides, and Structural Investigations written by Gérald Patrick Joseph Jean Louis Lelais and published by . This book was released on 2004 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Preparation of [beta]-amino Acids and Synthesis of [beta]-peptides with Novel Secondary Structures by : Stefan Abele
Download or read book Preparation of [beta]-amino Acids and Synthesis of [beta]-peptides with Novel Secondary Structures written by Stefan Abele and published by . This book was released on 1999 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Design, Synthesis, and Structural Investigation of Nucleobase Functionalized Β-peptides [beta-peptides] by : Pradip Chakraborty
Download or read book Design, Synthesis, and Structural Investigation of Nucleobase Functionalized Β-peptides [beta-peptides] written by Pradip Chakraborty and published by Cuvillier Verlag. This book was released on 2005 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis, Structure and Biological Investigations of [beta]-peptides by : Jürg Vital Schreiber
Download or read book Synthesis, Structure and Biological Investigations of [beta]-peptides written by Jürg Vital Schreiber and published by . This book was released on 2001 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis and Structural Investigations of [alpha]-peptides [alpha-peptides] Containing [beta]-aminocyclopropane [beta-aminocyclopropane] Dicarboxylic Acids by : Chiara Zorn
Download or read book Synthesis and Structural Investigations of [alpha]-peptides [alpha-peptides] Containing [beta]-aminocyclopropane [beta-aminocyclopropane] Dicarboxylic Acids written by Chiara Zorn and published by . This book was released on 2001 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Enantioselective Synthesis of Beta-Amino Acids by : Eusebio Juaristi
Download or read book Enantioselective Synthesis of Beta-Amino Acids written by Eusebio Juaristi and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Design, Synthesis, and Structural Investigation of Nucleobase Functionalized [beta]-peptides by : Pradip Chakraborty
Download or read book Design, Synthesis, and Structural Investigation of Nucleobase Functionalized [beta]-peptides written by Pradip Chakraborty and published by . This book was released on 2005 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis of Novel Beta - Amino Acids by : Irene Warden
Download or read book Synthesis of Novel Beta - Amino Acids written by Irene Warden and published by . This book was released on 1990 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis and Structural Investigations of Alpha-peptides Containing Beta-aminocyclopropane Dicarboxylic Acids by : Chiara Zorn
Download or read book Synthesis and Structural Investigations of Alpha-peptides Containing Beta-aminocyclopropane Dicarboxylic Acids written by Chiara Zorn and published by . This book was released on 2001 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis of Branched Α-[alpha-] and Β-amino[beta-amino] Acids Using C-nucleophile Additions to Imines and Nitrones by : Alevtina Baskakova
Download or read book Synthesis of Branched Α-[alpha-] and Β-amino[beta-amino] Acids Using C-nucleophile Additions to Imines and Nitrones written by Alevtina Baskakova and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Artificial peptides, containing alpha- and/or beta-amino acids with bulky substituents, can potentially possess some unusual properties, for example, decreased conformational ability or formation of stable secondary structures. Therefore, the preparation of such unnatural amino acids is of high interest. In this thesis, a route to enantiomerically pure 1-adamantylglycine was developed. The crucial step was the highly stereoselective addition of adamantylmagnesium bromide to the C=N bond of 2,3-O-cyclohexylidene-D-glyceraldehyde N-benzylnitrone effected in the presence of Lewis acid. Finally, 1-adamantylglycine was synthesized in 28 % yield over 6 steps. The routes to 9-aminofluorenylacetic and beta-aminobeta, beta-diphenylpropionic acids were proposed and they consist in the addition of allyl Grignard reagents to imines with various protecting groups, followed by oxidative transformation of the allyl group. Also some procedures for the preparation of 3,3-disubstituted 4-azetidinones, direct precursors of the corresponding beta-branched beta-amino acids, have been investigated.
Book Synopsis The Synthesis and Applications of Sulfoxide Ligands and Methodology Development Towards Beta-Amino Acid Incorporation in Peptides by : Priscilla Leung
Download or read book The Synthesis and Applications of Sulfoxide Ligands and Methodology Development Towards Beta-Amino Acid Incorporation in Peptides written by Priscilla Leung and published by . This book was released on 2011 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: The incorporation of beta-amino acid residues into polypeptides has resulted in new foldamers whose structures and enhanced stability provide interesting opportunities for new biological applications. A novel strategy for an iterative peptide synthesis involving beta-amino acids will be proposed. Lastly, a hydroamidation-type strategy for the construction of beta 3-amino acids, or more specifically of beta-(N-acylamino)acrylates, will be presented as preliminary work towards the goal of dipeptide synthesis.The use of sulfoxide ligands for transition metal catalyzed transformations has recently been brought to the forefront in organic chemistry. The synthesis of a series of tri- and disulfoxides will be presented, and their applications investigated. Their use in rhodium catalyzed 1,4-additions of phenylboronic acid to 2-cyclohexen-1-one result in enantioselectivities up to 80%.
Book Synopsis New Methods Towards the Synthesis of [beta]-amino Acids by : Barbara Weiner
Download or read book New Methods Towards the Synthesis of [beta]-amino Acids written by Barbara Weiner and published by . This book was released on 2009 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis of novel β - amino acids by : Irene Warden
Download or read book Synthesis of novel β - amino acids written by Irene Warden and published by . This book was released on 1990 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Peptide Therapeutics by : Ved Srivastava
Download or read book Peptide Therapeutics written by Ved Srivastava and published by Royal Society of Chemistry. This book was released on 2019-08-28 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptide therapy has become a key strategy in innovative drug development, however, one of the potential barriers for the development of novel peptide drugs in the clinic is their deficiencies in clearly defined chemistry, manufacturing and controls (CMC) strategy from clinical development to commercialization. CMC can often become a rate-limiting step due to lack of knowledge and lack of a formal policy or guidelines on CMC for peptide-based drugs. Regulators use a risk-based approach, reviewing applications on a case-by-case basis. Peptide Therapeutics: Strategy and Tactics for Chemistry, Manufacturing, and Controls covers efficient manufacturing of peptide drug substances, a review of the process for submitting applications to the regulatory authority for drug approval, a holistic approach for quality attributes and quality control from a regulatory perspective, emerging analytical tools for the characterisation of impurities, and the assessment of stability. This book is an essential reference work for students and researchers, in both academia and industry, with an interest in learning about CMC, and facilitating development and manufacture of peptide-based drugs.
Book Synopsis Fluorine-containing Amino Acids by : Valery P. Kukhar
Download or read book Fluorine-containing Amino Acids written by Valery P. Kukhar and published by John Wiley & Sons. This book was released on 1995-04-06 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, organo-fluorine chemistry has made a marked impact on the design and synthesis of a large variety of biologically active molecules, such as steroids, carbohydrates, amines, amino acids, peptides and other natural products. Naturally occurring amino acids play a pivotal role in living systems, and therefore synthetic fluorine-containing amino acids have been of significant interest to researchers working towards the understanding and modification of physiological processes. Fluorine-containing Amino Acids: is the first volume devoted to the synthesis and properties of fluorine-containing amino acids pays special attention to the preparation of enantiomerically pure acids (which are essential to the modern pharmaceutical industry) deals with a rapidly expanding field of research has been written by experienced researchers who are responsible for many developments in the field highlights the interdisciplinary nature of this topic Fluorine-containing Amino Acids is the only dedicated reference in this subject and will be essential for researchers in synthetic organic, peptide, natural product, and medicinal chemistry and biochemistry.
Book Synopsis Fmoc Solid Phase Peptide Synthesis by : W. Chan
Download or read book Fmoc Solid Phase Peptide Synthesis written by W. Chan and published by OUP Oxford. This book was released on 1999-12-16 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of Atherton and Sheppard's volume, the technique of Fmoc solid-phase peptide synthesis has matured considerably and is now the standard approach for the routine production of peptides. The focus of this new volume is much broader, and covers the essential procedures.
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