Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Synthesis Of Lanthanide Chelates For Biomedical Imaging
Download Synthesis Of Lanthanide Chelates For Biomedical Imaging full books in PDF, epub, and Kindle. Read online Synthesis Of Lanthanide Chelates For Biomedical Imaging ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Synthesis and Characterization of Lanthanide Chelates for Biomedical Imaging by : John Michael Mansfield Griffin
Download or read book Synthesis and Characterization of Lanthanide Chelates for Biomedical Imaging written by John Michael Mansfield Griffin and published by . This book was released on 2000 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis of Lanthanide Chelates for Biomedical Imaging by : Timothy Stephen O'Gara Goebel
Download or read book Synthesis of Lanthanide Chelates for Biomedical Imaging written by Timothy Stephen O'Gara Goebel and published by . This book was released on 2003 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Design and Synthesis of Novel Lanthanide Chelates for Use in Magnetic Resonance Imaging (MRI). by : Graeme James Stasiuk
Download or read book Design and Synthesis of Novel Lanthanide Chelates for Use in Magnetic Resonance Imaging (MRI). written by Graeme James Stasiuk and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis reports a series of novel Ln-DO3A based complexes, modulation of emission intensity (Eu and Tb) has been achieved and relaxivity, r1, (Gd) has been shown. Propargyl-appended lanthanide complexes derived from DO3A, has a hydration state, q = 2. They undergo Cu(I) catalysed cycloaddition reactions with azides to form 1,2,3-triazole appended complexes: coordination of one of the triazole nitrogen atoms to the metal centre changes the local coordination environment and luminescence studies indicate a hydration state of q = 1. Propargyl-appended Ln(III) complexes show unanticipated reactivity towards NaN3 in the Cu(I) catalysed 'click' reaction yielding an unsubstituted 1,2,3-triazole. The resulting Eu(III) complex exhibits pH-responsive 1H NMR and Ln(III) luminescence behaviour in the physiological pH range, consistent with deprotonation of the NH-acidic bound triazole. The coordination mode of the NH-triazole switches from NH-triazole bound in a pyridinic manner to bound in an anionic manner as a triazolide, while retaining a q = 1. This was demonstrated in luminescent studies of Eu(III) and Tb(III) complexes with a pKa ~ 7.5. Relaxation measurements on the Gd(III) analogue show a q =1 throughout the pH range, i.e. no change in hydration state. To overcome the unanticipated reactivity of NaN3 with propargyl-appended Ln(III) complexes, p-ethynylbenzyl-appended Ln(III) complexes were synthesised. These show promise as precursors for multimeric, self-associating and d-f hybrid complexes, via the Cu(I) catalysed cycloaddition or 'click' reaction. Luminescent studies show evidence of the formation of 1,2,3-triazoles that do not bind to the Ln(III) metal centre, with a hydration state q =1. These complexes have been applied in the synthesis of multimeric, self-associating and d-f hybrid compounds. Uridine was attached to a EuDO3A chelate via four different linkers. These complexes are precursors for an accumulation and activation strategy, developed as enzyme activated contrast agents. Neutral q = 1 Eu(III) uridine-DO3A based complexes were successfully synthesised and linked via a propyl, amide or 1,2,3-triazole unit.
Book Synopsis Synthesis and Characterization of a Lanthanide Chelate Imaging Agent for CEST Effect and Miltumodality by : Jordan Michael Fritz
Download or read book Synthesis and Characterization of a Lanthanide Chelate Imaging Agent for CEST Effect and Miltumodality written by Jordan Michael Fritz and published by . This book was released on 2008 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Lanthanides: Chemistry and Use in Organic Synthesis by : Shu Kobayashi
Download or read book Lanthanides: Chemistry and Use in Organic Synthesis written by Shu Kobayashi and published by Springer. This book was released on 2003-07-01 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts
Book Synopsis Synthesis of Macrocyclic Lanthanide Chelates for Anion Sensing and Magnetic Resonance Imaging Applications by : Christopher G. Gulgas
Download or read book Synthesis of Macrocyclic Lanthanide Chelates for Anion Sensing and Magnetic Resonance Imaging Applications written by Christopher G. Gulgas and published by . This book was released on 2007 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: Novel Eu3-containing macrocyclic complexes were synthesized and studied as anion sensing probe molecules. Several of these macrocycles exhibited unique luminescence responses to hydrogen-bond accepting anions (fluoride, acetate, and dihydrogen phosphate) in DMSO, even in the presence of a chloride ion background. The first series of compounds highlighted a high-yielding synthetic route for highly functional macrocycles that incorporate a Eu3 chelate, aromatic antennae, thiourea groups as anion-binding units, and a variable linker that tunes the size and rigidity of the pocket. These macrocycles exhibited Eu3 luminescence where emission intensity ([lambda]exc = 272 nm, [lambda]em = 614 nm) was correlated to the linker length. Anion-induced changes in emission intensity were dependent on the basicity of the anion, and emission enhancements were observed up to 77% upon titration with fluoride in one case. Through luminescence lifetime studies of the Eu3+ macrocycles and the study of a newly synthesized series of organic model compounds, it was determined that the luminescence response to anions was the result of interaction with the thiourea moieties and no evidence was observed for anion coordination to Eu3+. Additionally, two second-generation macrocycles were synthesized, incorporating an amine unit for stronger binding affinity. One of these macrocycles, featuring a pendant naphthalene antenna, responded to several anions in aqueous solution by means of a luminescence decrease of up to 30%. This general macrocyclic design shows promise for the development of Eu3+-based anion sensors that function in competitive solvents. In continuing work with lanthanide complexes, a new targeted Gd3+-based magnetic resonance imaging contrast agent was designed and synthesized for specific binding to the dopamine receptor protein. A relaxivity of 7.1 mM−1s−1 was measured for this complex at 400 mHz and 310 K.A Eu3+ analogue was also synthesized and structurally characterized. Luminescence lifetime measurements revealed the presence of 2 coordinated water molecules in aqueous solution, consistent with the observed relaxivity of the Gd3+ complex. The synthetic scheme described herein can be extended to the synthesis of a series of targeted complexes for enhanced dopamine receptor binding and imaging studies.
Book Synopsis Lanthanide Complexes of Bifunctional Chelates as PH and Ca2+ Sensitive Contrast Agents for MR Imaging by : Ilgar Mammadov
Download or read book Lanthanide Complexes of Bifunctional Chelates as PH and Ca2+ Sensitive Contrast Agents for MR Imaging written by Ilgar Mammadov and published by . This book was released on 2006 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Hydroxyl-bridged Lanthanide Amino Acid Clusters and Hexatantalum and Hexatungsten Chloride Clusters by : David Alan Rotsch
Download or read book Hydroxyl-bridged Lanthanide Amino Acid Clusters and Hexatantalum and Hexatungsten Chloride Clusters written by David Alan Rotsch and published by . This book was released on 2011 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electrospray ionization mass spectroscopy (ESI-MS) on the Eu(III)-based clusters showed mass-to-charge peaks representative of the intact cluster core minus several counter ions and ligands. Yttrium analogues were prepared for 13 C and 89 Y NMR spectroscopy studies. The 13 C NMR spectra exhibited two sets of resonances for histidine. One set matches that of free-histidine in aqueous solution, and the other most likely represents yttrium-coordinated histidine. 89 Y NMR spectra exhibited two resonances and correlate with the solid-state structure. Solution-state studies of the Ln 15 -his X complexes suggest that the Ln 15 -his X clusters maintain the observed solid-state structure in solution. Inner-ligand-substituted hexanuclear tantalum and tungsten chloride clusters were also investigated. Substitution of inner chlorines by metathesis of the robust cluster cores in solution proved to be challenging. Solid-state synthesis to obtain mixed oxygen-chlorine hexatantalum clusters resulted in ampoule explosions because of side reactions between the reactants and the quartz ampoule. Solid-state routes towards tungsten clusters with mixed inner ligands yielded the (H 3 O) 2 [[alpha/beta]-W 6 ([micro] 2 -O) 6 ([micro] 2 -Cl) 6 Cl 6]*X(H 2 O) (X [alpha] = 4; X [beta] = 6) complexes.
Book Synopsis Synthesis and Study of Lanthanide Complexes as MRI Contrast Agents by :
Download or read book Synthesis and Study of Lanthanide Complexes as MRI Contrast Agents written by and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Multi-disciplinary Study of Lanthanide Chelates as Multi-modal Molecular Imaging Agents by : Henry Charles Manning
Download or read book Multi-disciplinary Study of Lanthanide Chelates as Multi-modal Molecular Imaging Agents written by Henry Charles Manning and published by . This book was released on 2004 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Lanthanides written by Shu Kobayashi and published by Springer. This book was released on 2014-01-15 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of lanthanides in organic chemistry and in organic synthesis has attracted broad interest recently because of the unique reactivities and selectivities exhibited by compounds of these rare earth elements. In particular, several major advances have been made in the last five years. This volume of "Topics in Organometallic Chemistry" is designed to provide the specialist and non-specialist alike with a much needed overview of recent developments. Contributions by leaders in the field focus on stereoselective organic synthesis using lanthanides, the principles of lanthanide chemistry, lanthanide-based chiral catalysts, low-valent lanthanide compounds, polymer synthesis using lanthanide catalysts, and polymer-supported lanthanide catalysts used in organic synthesis.
Book Synopsis Biomedical Photonics Handbook by : Tuan Vo-Dinh
Download or read book Biomedical Photonics Handbook written by Tuan Vo-Dinh and published by CRC Press. This book was released on 2014-07-29 with total page 767 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shaped by Quantum Theory, Technology, and the Genomics RevolutionThe integration of photonics, electronics, biomaterials, and nanotechnology holds great promise for the future of medicine. This topic has recently experienced an explosive growth due to the noninvasive or minimally invasive nature and the cost-effectiveness of photonic modalities in
Book Synopsis Lanthanide-Doped Luminescent Nanomaterials by : Xueyuan Chen
Download or read book Lanthanide-Doped Luminescent Nanomaterials written by Xueyuan Chen and published by Springer Science & Business Media. This book was released on 2013-11-04 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lanthanide-Doped Luminescent Nanomaterials reviews the latest advances in the development of lanthanide-doped luminescent inorganic nanoparticles for potential bioapplications. This book covers the chemical and physical fundamentals of these nanoparticles, such as the controlled synthesis methodology, surface modification chemistry, optical physics, and their promising applications in diverse bioassays, with an emphasis on heterogeneous and homogeneous in-vitro biodetection of tumor biomarkers. This book is intended for those readers who are interested in systematically understanding the materials design strategy, optical behavior of lanthanide ions, and practical bioapplications of lanthanide nanoparticles. It primarily focuses on the interdisciplinary frontiers in chemistry, physics and biological aspects of luminescent nanomaterials. All chapters were written by scientists active in this field and for a broad audience, providing both beginners and advanced researchers with comprehensive information on the subject. Xueyuan Chen is a Professor at Fujian Institute of Research on the Structure of Matter (FJIRSM), Chinese Academy of Sciences. Yongsheng Liu is a Research Associate Professor at FJIRSM, Chinese Academy of Sciences. Datao Tu is a Research Assistant Professor at FJIRSM, Chinese Academy of Sciences.
Book Synopsis Biomedical Photonics Handbook, 3 Volume Set by : Tuan Vo-Dinh
Download or read book Biomedical Photonics Handbook, 3 Volume Set written by Tuan Vo-Dinh and published by CRC Press. This book was released on 2014-07-29 with total page 2465 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook presents the most recent technological advances and applications in the areas of biomedical photonics. This second edition contains introductory material and covers the state-of-the-art methods and instrumentation for biomedical photonic technologies. It integrates interdisciplinary research and development critically needed for scientists, engineers, manufacturers, teachers, students, and clinical providers to learn about the most recent advances and predicted trends in instrumentation and methods as well as clinical applications in important areas of biomedical photonics. Extensive references are provided to enhance further study.
Book Synopsis Handbook on the Physics and Chemistry of Rare Earths by : Pecharsky Vitalij
Download or read book Handbook on the Physics and Chemistry of Rare Earths written by Pecharsky Vitalij and published by Elsevier. This book was released on 2020-08-27 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook on the Physics and Chemistry of Rare Earths: Including Actinides, Volume 57, is a continuous series of books covering all aspects of rare earth science, including chemistry, life sciences, materials science and physics. The book's main emphasis is on rare earth elements [Sc, Y, and the lanthanides (La through Lu], but whenever relevant, information is also included on the closely related actinide elements. Presents up-to-date overviews and new developments in the field of rare earths, covering both their physics and chemistry Contains Individual chapters that are comprehensive and broad, along with critical reviews Provides contributions from highly experienced, invited experts
Book Synopsis Lanthanide Luminescence by : Pekka Hänninen
Download or read book Lanthanide Luminescence written by Pekka Hänninen and published by Springer Science & Business Media. This book was released on 2011-06-21 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lanthanides have fascinated scientists for more than two centuries now, and since efficient separation techniques were established roughly 50 years ago, they have increasingly found their way into industrial exploitation and our everyday lives. Numerous applications are based on their unique luminescent properties, which are highlighted in this volume. It presents established knowledge about the photophysical basics, relevant lanthanide probes or materials, and describes instrumentation-related aspects including chemical and physical sensors. The uses of lanthanides in bioanalysis and medicine are outlined, such as assays for in vitro diagnostics and research. All chapters were compiled by renowned scientists with a broad audience in mind, providing both beginners in the field and advanced researchers with comprehensive information on on the given subject.
Download or read book Master's Theses Directories written by and published by . This book was released on 2004 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Education, arts and social sciences, natural and technical sciences in the United States and Canada".
