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Syndromes Of Hormone Resistance On The Hypothalamic Pituitary Thyroid Axis
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Book Synopsis Syndromes of Hormone Resistance on the Hypothalamic-Pituitary-Thyroid Axis by : Paolo Beck-Peccoz
Download or read book Syndromes of Hormone Resistance on the Hypothalamic-Pituitary-Thyroid Axis written by Paolo Beck-Peccoz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Truly unique cutting edge state of the art information on basic and clinical research. A great help for the clinician to diagnose and treat this uncommon hormone resistance. Basic scientists learn how much has been discovered on the mechanism of hormone action from the mutations of the various genes involved to thyroid hormones and TSH.
Book Synopsis Genetics of Endocrine Diseases and Syndromes by : Peter Igaz
Download or read book Genetics of Endocrine Diseases and Syndromes written by Peter Igaz and published by Springer Nature. This book was released on 2019-10-06 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the genetic basis underlying endocrine diseases. It covers both the molecular and clinical consequences of these genetic defects, as well as the relevance for clinical care, highlighting issues of genetic counseling. Several endocrine diseases have a genetic background, and contemporary research in the field plays a crucial role in the clinical care of endocrine diseases. In recent years, there have been major developments in our understanding of the genetic basis of endocrine diseases. Several novel genes and mutations predisposing individuals to monogenic endocrine diseases have been discovered, and with the advent of next generation sequencing, a huge amount of new data has become available. Further, novel molecular mechanisms, such as genomic imprinting, have been implicated in the pathogenesis of endocrine diseases. A better understanding of the genetic background of these diseases is relevant not only from the research perspective, but also in terms of clinical care. As such, this book is an essential read for both researchers and clinicians working in the field.
Book Synopsis The Thyroid and Its Diseases by : Markus Luster
Download or read book The Thyroid and Its Diseases written by Markus Luster and published by Springer. This book was released on 2019-01-08 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an up-to-date and comprehensive guide to all the common thyroid disorders that may be seen by internists, endocrinologists, nuclear medicine physicians, and endocrine surgeons. While the fundamentals of thyroid hormone function and regulation in health and disease are well covered, the primary focus is on the clinical approach to thyroid disease, with detailed coverage of both initial diagnosis and management and the role of imaging. Because most endocrine diseases are chronic and lifelong, special emphasis is placed on long-term management and the common pitfalls that may be encountered by the clinician. The editors are internationally acknowledged leaders in the field of thyroid disease and have gathered an outstanding team of authors, all of whom are also highly expert in their respective areas, but who, equally importantly, write in a clear and lucid style. The numerous isotope scan and ultrasonographic images ensure that the book will serve as a valuable reference atlas to which the physician will return again and again.
Book Synopsis Clinical Neuroendocrinology by : Michael Wilkinson
Download or read book Clinical Neuroendocrinology written by Michael Wilkinson and published by Cambridge University Press. This book was released on 2019-01-03 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise and innovative account of clinical neuroendocrine disorders and the key principles underlying their diagnosis and management.
Book Synopsis Handbook of Famine, Starvation, and Nutrient Deprivation by : Victor R. Preedy
Download or read book Handbook of Famine, Starvation, and Nutrient Deprivation written by Victor R. Preedy and published by Springer. This book was released on 2019-03-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the causes and effects of nutrient deficiencies along the cell-to-communities continuum. The book is primarily concerned with a lack or deficiency of one or more micro- or macronutrients in connection with malnutrition, under nutrition, and starvation. Embedded within the deficiency states is acute restriction whereby food is withdrawn completely for short periods, as when individuals are adhering to religious requirements or undergoing surgical procedures. Further downstream is the consumption of a fraction of the normal diet, as when individuals are dieting or when there is restriction in the amount or variety of food available. The causes of such reductions in dietary intake are varied and also include the social context of poverty, financial limitations, and famine. Refugees and displaced persons may also be vulnerable to under nutrition or total starvation. Diseases may also impact on the total food consumed, such as when there are physical impediments (intestinal obstruction or dysphagia) or anorexia (induced by organic disease or as a disease process per se, ie, anorexia nervosa). This book, organized as approximately 125 chapters in 17 major sections, covers the variable manifestations of dietary restrictions on cells, whole organs, the individual, and societies.
Book Synopsis Endemic Cretinism by : John Dennison
Download or read book Endemic Cretinism written by John Dennison and published by Springer Science & Business Media. This book was released on 2011-09-25 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Responding to a renewed interest in the growing problem of iodine deficiency worldwide, Drs. Charles Oxnard and Peter Obendorf, along with experienced translator and anatomist John Dennison, take a fresh look at the classic text, Der endemische Kretinismus, published in 1936 by Springer. Translated here for the first time into English, this landmark text will be a welcome resource for researchers confronting the problem of iodine deficiency. Oxnard and Obendorf point out that there is very little detailed knowledge or numerical data on cretinism available in the English-speaking world. In addition, highly-renowned Professor Basil S. Hetzel, recently-retired World Health Organization Chairman of the International Council for Control of Iodine Deficiency Disorders, published in 2009 with Dr Chen Zu-pei on the resurgence of iodine deficiency in China. Indeed, throughout the entire developing world there may be as many as two billion people at risk to iodine deficiency; perhaps three quarters of a billion have goiter, and ten million may be cretins. Even in developed countries, iodine deficiency is re-emerging (as in New South Wales in 19% of children) with the result of significantly reduced numbers of gifted children (though this is not cretinism per se). Certain to be of significant interest to a wide range of researchers, health providers and professionals, including government health administrators, this English translation of Endemic Cretinism is a major contribution to the literature.
Book Synopsis Paediatric Thyroidology by : G. Szinnai
Download or read book Paediatric Thyroidology written by G. Szinnai and published by Karger Medical and Scientific Publishers. This book was released on 2014-09-15 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a comprehensive overview of pediatric thyroid diseases and thus provides a useful tool for clinical problem solving. Opinion leaders in the field present reviews on all relevant diseases of the hypothalamic-pituitary-thyroid axis. Sixteen chapters cover topics ranging from fetal thyroidology, congenital hypothyroidism, central hypothyroidism, inherited defects of thyroid hormone action, cell transport and metabolism to iodine deficiency, autoimmune thyroid disease and thyroid tumors. Written by clinicians, the chapters provide in-depth information and current guidelines for clinical problems encountered in pediatric thyroidology. As a unique feature, a case seminar collection for each chapter presents typical patient histories providing key learning points and key references for clinical problem solving in family medicine, pediatric endocrinology and medical genetics. Providing a succinct update on clinical pediatric thyroidology, this book is an essential tool for pediatric and adult endocrinologists, as well as for general practitioners, pediatricians and medical geneticists.
Download or read book Endocrinology written by S.S. Nussey and published by CRC Press. This book was released on 2001-06-15 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditionally, endocrinology textbooks have been either short notes or multi-author, multi-volume monster, all of which present clinical material last and often only briefly. Endocrinology is different and used real cases to lead readers into the text and then describes the biochemistry, physiology, and anatomy they need to understand the case. The
Book Synopsis Hypothalamic-Pituitary Diseases by : Felipe F. Casanueva
Download or read book Hypothalamic-Pituitary Diseases written by Felipe F. Casanueva and published by Springer. This book was released on 2018-04-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the state of the art in the pathophysiology, diagnosis, and therapy of hypothalamic and pituitary disorders. After an introduction devoted to the physiology of the neuroendocrine control of the hypothalamic-pituitary unit, the diverse disorders involving hormonal excess or deficiency are systematically addressed axis by axis. For each disorder, pathophysiology, clinical presentation, and management are discussed in detail. In addition, individual chapters focus on the neuroendocrinology of energy homeostasis and of bone metabolism, metabolic derangement secondary to pituitary dysfunction, and pituitary control of the endocrine pancreas. While the focus of the book is predominantly on pathophysiological and clinical aspects, due attention is also devoted to potential diagnostic and therapeutic innovations. The book is intended as a major reference for endocrinologists and basic and clinical scientists.
Book Synopsis 70 Years of Levothyroxine by : George J. Kahaly
Download or read book 70 Years of Levothyroxine written by George J. Kahaly and published by Springer Nature. This book was released on 2021-03-11 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book presents the history, pharmacokinetics and pharmacodynamics of levothyroxine, discussing its role in the thyroid pathophysiology of patients of various ages and during pregnancy. It also describes the influence of levothyroxine on heart, bone and in cancer. When it was first synthesized in 1949, levothyroxine represented a significant advance in the treatment of hypothyroidism, providing a safe and effective treatment option for millions of hypothyroid patients around the globe. This synthetic form of thyroxine is now one of the most prescribed drugs in the world. Levothyroxine was first introduced by Merck KGaA,Darmstadt, Germany, in 1972, and since then the company has remained actively engaged in research on this mainstay of hypothyroidism treatment. This book is intended for healthcare professionals.
Book Synopsis Hormone Resistance Syndromes by : J. Larry Jameson
Download or read book Hormone Resistance Syndromes written by J. Larry Jameson and published by Springer Science & Business Media. This book was released on 1999-01-26 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading clinicians review in depth the clinical and molecular aspects of the hormone resistance syndromes caused by receptor mutations. These mutations are involved in a large number of disorders, including dwarfism, Laron syndrome, pseudohypoparathyroidism, insulin resistance, resistance to thyroid hormone, glucocorticoid resistance, hereditary resistance to vitamin D, and estrogen resistance. Throughout, the book's distinguished contributors not only summarize the clinical features of these and related disorders, but also illuminate their molecular bases. Hormone Resistance Syndromes provides an authoritative summary and standard reference for all those clinicians and researchers actively studying these mutations today and affords a unique opportunity to understand hormone action in normal physiology.
Book Synopsis The Human Hypothalamus by : Gabriel I. Uwaifo
Download or read book The Human Hypothalamus written by Gabriel I. Uwaifo and published by Springer Nature. This book was released on 2020-12-24 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hypothalamus is an anatomically small but functionally important part of the brain. In functional and pathophysiological terms, the hypothalamus represents the intersection of several areas of clinical and medical expertise. The human hypothalamus can be astutely referred to as the crossroad of endocrinology, psychiatry, neurology and neurosurgery. Because of its involvement in myriad physiologic functions and the varied ways disorders involving it can manifest, hypothalamic disease can initially come to medical attention in widely disparate settings and with widely different clinicians. Therefore, the detection and proper care of hypothalamic dysfunction and disease often requires carefully coordinated multidisciplinary care. This volume fills a significant void in the medical professional community, comprehensively presenting the scope of hypothalamic structure, function, dysfunction and disease to cater to the various clinical, teaching and research professionals that have a stake in this part of the human brain. This text captures in one place all the information that practicing clinicians, clinician scientists, and researchers need to be adequately informed about various aspects of the hypothalamus in all its complexity. It is comprehensive and broad in scope so that it provides relevant reference information for the wide range of professionals involved in the pre- and post-mortem detection, diagnosis, characterization, care and management of various hypothalamic disorders and diseases in addition to providing a sound anatomic and physiologic foundation of the normal human hypothalamus. The Human Hypothalamus can be used to differing degrees by medical professionals and students alike, finding utility for interested general clinicians, medical school and allied health professional teaching faculty as well as subspecialists in domains as wide as neurosurgery, neuroendocrinology, clinical psychiatry and neuro-oncology.
Book Synopsis Hormone Resistance and Hypersensitivity by : M. Maghnie
Download or read book Hormone Resistance and Hypersensitivity written by M. Maghnie and published by Karger Medical and Scientific Publishers. This book was released on 2013-02-04 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over recent years, impressive advances in genetic/epigenetic technology have greatly improved the understanding of the pathogenesis of pediatric endocrine diseases due to hormone resistance and hypersensitivity.This book presents reviews of thyroid hormone and thyroid hormone receptor resistance, and genetics and epigenetics of parathyroid hormone resistance. Abnormalities of the pituitary-gonadal axis affecting puberty as well as androgen receptor are covered. Novel insights into the diseases affecting ACTH, glucocorticoid and aldosterone receptors are discussed. Further chapters address new aspects of the physiology of the GH and IGF-1 axis as well as the diseases related to GH-IGF-1 receptor and post-receptor signaling defects. A key chapter on metabolic insights into insulin resistance is also included. Covering clinical and genetic aspects of hormone resistance and hypersensitivity, this book will be a useful tool in the hands of scientists, physicians and other healthcare professionals who wish to be up to date with novel research findings in this area.
Book Synopsis Polycystic Ovary Syndrome by : Andrea Dunaif
Download or read book Polycystic Ovary Syndrome written by Andrea Dunaif and published by Springer Science & Business Media. This book was released on 2008-01-12 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume includes the latest diagnostic criteria for PCOS and comprises the most up-to-date information about the genetic features and pathogenesis of PCOS. It critically reviews the methodological approaches and the evidence for various PCOS susceptibility genes. The book also discusses additional familial phenotypes of PCOS and their potential genetic basis. All four editors of this title are extremely prominent in the field of PCOS.
Book Synopsis Oxford Textbook of Endocrinology and Diabetes by : John A.H. Wass
Download or read book Oxford Textbook of Endocrinology and Diabetes written by John A.H. Wass and published by Oxford University Press, USA. This book was released on 2011-07-28 with total page 2158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, the Oxford Textbook of Endocrinology and Diabetes is a fully comprehensive, evidence-based, and highly-valued reference work combining basic science with clinical guidance, and providing first rate advice on diagnosis and treatment.
Download or read book The Pituitary written by Shlomo Melmed and published by Academic Press. This book was released on 2010-12-09 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pituitary, albeit a small gland, is known as the "master gland" of the endocrine system and contributes to a wide spectrum of disorders, diseases, and syndromes. Since the publication of the second edition of The Pituitary, in 2002, there have been major advances in the molecular biology research of pituitary hormone production and action and there is now a better understanding of the pathogenesis of pituitary tumors and clinical syndromes resulting in perturbation of pituitary function. There have also been major advances in the clinical management of pituitary disorders. Medical researchers and practitioners now better understand the morbidity and mortality associated with pituitary hormone hyposecretion and hypersecretion. Newly developed drugs, and improved methods of delivering established drugs, are allowing better medical management of acromegaly and prolactinoma. These developments have improved the worldwide consensus around the definition of a "cure" for pituitary disease, especially hormone hypersecretion, and hence will improve the success or lack of success of various forms of therapy. It is therefore time for a new edition of The Pituitary. The third edition will continue to be divided into sections that summarize normal hypothalamic-pituitary development and function, hypothalamic-pituitary failure, and pituitary tumors; additional sections will describe pituitary disease in systemic disorders and diagnostic procedures, including imaging, assessment of the eyes, and biochemical testing. The first chapter will be completely new – placing a much greater emphasis on physiology and pathogenesis. Two new chapters will be added on the Radiation and Non-surgical Management of the Pituitary and Other Pituitary Lesions. Other chapters will be completely updated and many new author teams will be invited. The second edition published in 2002 and there have been incredible changes in both the research and clinical aspects of the pituitary over the past 8 years – from new advances in growth hormones to pituitary tumor therapy. Presents a comprehensive, translational source of information about the pituitary in one reference work Pituitary experts (from all areas of research and practice) take readers from the bench research (cellular and molecular mechanism), through genomic and proteomic analysis, all the way to clinical analysis (histopathology and imaging) and new therapeutic approaches Clear presentation by endocrine researchers of the cellular and molecular mechanisms underlying pituitary hormones and growth factors as well as new techniques used in detecting lesions (within the organ) and other systemic disorders Clear presentation by endocrinologists and neuroendocrine surgeons of how imaging, assessment of the eyes, and biochemical testing can lead to new therapeutic approaches
Download or read book Thyroid Diseases written by Paolo Vitti and published by Springer. This book was released on 2018-09-09 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest advances in knowledge of the pathogenesis of thyroid diseases and describes the state of the art in their diagnosis and treatment, including newly emerging management approaches. After an opening section that addresses thyroid physiology and laboratory evaluation, each of the major thyroid diseases and their subtypes is discussed, covering goiter and thyroid nodule, thyroiditis, hypothyroidism, hyperthyroidism and thyrotoxicosis, and thyroid carcinoma. Other conditions that affect thyroid function or induce thyroid dysfunction are also considered, e.g., pregnancy, non-thyroidal disorders, and medication use. The book is designed to assist practitioners to achieve optimal outcomes in clinical routine by providing clear guidance on clinical examination, the use of diagnostic tests, first- and second-line therapies, and follow-up. Chapter have been written by recognized experts in the field.
