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Author : David Johnston Steward
Publisher :
ISBN 13 : 9781621823957
Total Pages : 310 pages
Book Rating : 4.8/5 (239 download)
Download or read book RNA Control and Regulation written by David Johnston Steward and published by . This book was released on 2019 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dorcas Cummings Lecture:Dorcas Cummings Lecture.
Author :
Publisher :
ISBN 13 :
Total Pages : 594 pages
Book Rating : 4.3/5 (91 download)
Download or read book Symposium on RNA Biology II, RNA, Tool and Target written by and published by . This book was released on 1997 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Gisela Storz
Publisher : John Wiley & Sons
ISBN 13 : 1683672941
Total Pages : 1102 pages
Book Rating : 4.6/5 (836 download)
Download or read book Regulating with RNA in Bacteria and Archaea written by Gisela Storz and published by John Wiley & Sons. This book was released on 2018-11-01 with total page 1102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Revealing the many roles of RNA in regulating gene expression For decades after the discoveries of messenger RNA, transfer RNA, and ribosomal RNA, it was largely assumed that the role of RNA in the cell was limited to shuttling the genomic message, chaperoning amino acids, and toiling in the ribosomes. Eventually, hints that RNA molecules might have regulatory roles began to appear. With the advent of genomics and bioinformatics, it became evident that numerous other RNA forms exist and have specific functions, including small RNAs (sRNA), RNA thermometers, and riboswitches to regulate core metabolic pathways, bacterial pathogenesis, iron homeostasis, quorum sensing, and biofilm formation. All of these functions, and more, are presented in Regulating with RNA in Bacteria and Archaea, written by RNA biologists from around the globe. Divided into eight sections-RNases and Helicases, Cis-Acting RNAs, Cis Encoded Base Pairing RNAs, Trans-Encoded Base Pairing RNAs, Protein Titration and Scaffolding, General Considerations, Emerging Topics, and Resources-this book serves as an excellent resource for established RNA biologists and for the many scientists who are studying regulated cellular systems. It is no longer a fair assumption that gene expression regulation is the provenance of proteins only or that control is exerted primarily at the level of transcription. This book makes clear that regulatory RNAs are key partners along with proteins in controlling the complex interactions and pathways found within prokaryotes.
Author : A. Krishna Prasad
Publisher : Royal Society of Chemistry
ISBN 13 : 178801877X
Total Pages : 323 pages
Book Rating : 4.7/5 (88 download)
Download or read book Vaccine Development: From Concept to Clinic written by A. Krishna Prasad and published by Royal Society of Chemistry. This book was released on 2022-11-09 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Utilising successful case studies Vaccine Development will provide insight to the issues scientists face when producing a vaccine, the steps involved and will serve as an ideal reference tool regarding state-of-the-art vaccine development.
Author : Dóra Szakonyi
Publisher : Frontiers Media SA
ISBN 13 : 2889630250
Total Pages : 167 pages
Book Rating : 4.8/5 (896 download)
Download or read book Plant RNA Biology written by Dóra Szakonyi and published by Frontiers Media SA. This book was released on 2019-11-18 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discoveries from the past decades revealed that RNA molecules are much more than inert intermediates between the coding DNA sequences and their functional products, proteins. Today, RNAs are recognized as active regulatory molecules influencing gene expression, chromatin organization and genome stability, thus impacting all aspects of plant life including development, growth, reproduction and stress tolerance. Innovations in methodologies, the expanding application of next-generation sequencing technologies, and the creation of public datasets and databases have exposed a new universe of RNA-based mechanisms and led to the discovery of new families of non-coding RNAs, uncovered the large extent of alternative splicing events, and highlighted the potential roles of RNA modifications and RNA secondary structures. Furthermore, considerable advances have been made in identifying RNA-binding and processing factors involved in the synthesis and maturation of different forms of RNA molecules as well as in RNA processing, biochemical modifications or degradation. This Research Topic showcases the broad biological significance of RNAs in plant systems and contains eight original research articles, one review and four mini-reviews, covering various RNA-based mechanisms in higher plants. Emerging new technologies and novel multidisciplinary approaches are empowering the scientific community and will expectedly bring novel insights into our understanding of the mechanisms through which RNA is regulated and regulates biological processes in plant cells.
Author : Masayori Inouye
Publisher :
ISBN 13 :
Total Pages : 472 pages
Book Rating : 4.3/5 (91 download)
Download or read book Molecular Biology of RNA written by Masayori Inouye and published by . This book was released on 1987 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology of RNA: New Perspectives provides an overview of the developments in RNA research as well as the approaches, strategies, and methodologies used. Most of the contributing authors in the present volume participated in the Fifth Stony Brook Symposium entitled ""New Perspectives on the Molecular Biology of RNA"" in May 1986. The text is organized into six parts. Part I contains papers dealing with RNA as an enzyme. Part II presents studies on RNA splicing. Part III examines RNA viruses while Part IV focuses on the role of RNA in DNA replication. Part V is devoted to the structure ...
Author : Cherilyn Jose
Publisher :
ISBN 13 : 9781682863510
Total Pages : 0 pages
Book Rating : 4.8/5 (635 download)
Download or read book Parasitology and Vector Biology written by Cherilyn Jose and published by . This book was released on 2016-05-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parasitic and vector borne diseases are a major threat to health of humans and other organisms in present day scenario. It is necessary to study these diseases to understand the cause and to ensure better control measures. This book on parasitology and vector biology provides readers with in-depth knowledge of various parasites, their hosts, and the relationship between them. Different approaches, evaluations, methodologies and advanced studies on helminthology, parasitism, DNA sequence markers, and host-pathogen interactions have been included in this book. It will help students and researchers in gaining a comprehensive insight into the field.
Author : Howard J. Teas
Publisher : University Press of Kentucky
ISBN 13 : 0813183545
Total Pages : 185 pages
Book Rating : 4.8/5 (131 download)
Download or read book Genetics and Developmental Biology written by Howard J. Teas and published by University Press of Kentucky. This book was released on 2021-05-11 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: These essays—the outgrowth of a symposium sponsored by the University of Kentucky to honor one of its most distinguished graduates, Nobel Prize laureate Thomas Hunt Morgan—provide a representative view of research interests in specific areas of molecular biology. The fifteen contributors to this volume are among the most distinguished scientists in America.
Author : Irwin Rubenstein
Publisher : Elsevier
ISBN 13 : 1483272427
Total Pages : 362 pages
Book Rating : 4.4/5 (832 download)
Download or read book Molecular Biology of Plants written by Irwin Rubenstein and published by Elsevier. This book was released on 2013-10-22 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology of Plants presents the formal scientific presentations delivered on the symposium on plant molecular biology, held at the University of Minnesota in 1976. The topics in this book are organized around the central dogma of molecular biology. Section I describes the organization and replication of DNA in plant chromosomes, including chloroplast genomes; Section II discusses molecular aspects of transcription and translation, ribosomal RNA gene systems and hormonal control of protein synthesis. Section III examines plant viruses and bacterial agents, in particular the crown gall system, viroids, and the replication of plant RNA viruses. Each of these specific topics contributes to an integrated knowledge of plant molecular biology. The book will be of interest to geneticists, cell biologists, plant breeders, plant physiologists, plant pathologists, and biochemists.
Author : Robert J Marks II
Publisher : World Scientific Publishing Company
ISBN 13 : 9814508721
Total Pages : 584 pages
Book Rating : 4.8/5 (145 download)
Download or read book Biological Information written by Robert J Marks II and published by World Scientific Publishing Company. This book was released on 2013-06-03 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the spring of 2011, a diverse group of scientists gathered at Cornell University to discuss their research into the nature and origin of biological information. This symposium brought together experts in information theory, computer science, numerical simulation, thermodynamics, evolutionary theory, whole organism biology, developmental biology, molecular biology, genetics, physics, biophysics, mathematics, and linguistics. This volume presents new research by those invited to speak at the conference. The contributors to this volume use their wide-ranging expertise in the area of biological information to bring fresh insights into the many explanatory difficulties associated with biological information. These authors raise major challenges to the conventional scientific wisdom, which attempts to explain all biological information exclusively in terms of the standard mutation/selection paradigm. Several clear themes emerged from these research papers: 1) Information is indispensable to our understanding of what life is; 2) Biological information is more than the material structures that embody it; 3) Conventional chemical and evolutionary mechanisms seem insufficient to fully explain the labyrinth of information that is life. By exploring new perspectives on biological information, this volume seeks to expand, encourage, and enrich research into the nature and origin of biological information.
Author : Stefan Jurga
Publisher : Springer Nature
ISBN 13 : 3030716120
Total Pages : 632 pages
Book Rating : 4.0/5 (37 download)
Download or read book Epitranscriptomics written by Stefan Jurga and published by Springer Nature. This book was released on 2021-07-28 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews a novel and exciting field of cellular and molecular biology called epitranscriptomics, which focuses on changes in an organism’s cells resulting from the posttranscriptional modification of cellular RNA. RNA-binding proteins (RBPs) play a crucial role in these posttranscriptional modifications and also support several cellular processes necessary for maintaining RNA homeostasis. Exploring the mechanisms underlying RNA modifications and RBP function is an emerging area of biomedical research, taking the study of gene regulation a step beyond epigenetics. This book reveals that the RNA molecule is not just an information-carrying molecule with some secondary structures. Accordingly, how RNA is modified, regulated, packaged, and controlled is an important aspect. Leading experts address questions such as where the over 170 distinct posttranscriptional RNA modifications are located on the genome, what percentage of mRNAs and noncoding RNAs these modifications include, and how an RNA modification impacts a person’s biology. In closing, the book reviews the role of RNA modifications and RBPs in a variety of diseases and their pathogenesis. Addressing some of the most exciting challenges in epitranscriptomics, this book provides a valuable and engaging resource for researchers in academia and industry studying the phenomena of RNA modification.
Author : Michael B. Mathews
Publisher :
ISBN 13 : 9781621821861
Total Pages : 499 pages
Book Rating : 4.8/5 (218 download)
Download or read book Translation Mechanisms and Control written by Michael B. Mathews and published by . This book was released on 2018-09-30 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: A subject collection from Cold Spring Harbor Perspectives in Biology.
Author : Wei-Shu Hu
Publisher : Springer
ISBN 13 : 3540340076
Total Pages : 179 pages
Book Rating : 4.5/5 (43 download)
Download or read book Cell Culture Engineering written by Wei-Shu Hu and published by Springer. This book was released on 2006-08-16 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the introduction of recombinant human growth hormone and insulin a quarter century ago, protein therapeutics has greatly broadened the ho- zon of health care. Many patients suffering with life-threatening diseases or chronic dysfunctions, which were medically untreatable not long ago, can attest to the wonder these drugs have achieved. Although the ?rst generation of p- tein therapeutics was produced in recombinant Escherichia coli, most recent products use mammalian cells as production hosts. Not long after the ?rst p- duction of recombinant proteins in E. coli, it was realized that the complex tasks of most post-translational modi?cations on proteins could only be ef?ciently carried out in mammalian cells. In the 1990s, we witnessed a rapid expansion of mammalian-cell-derived protein therapeutics, chie?y antibodies. In fact, it has been nearly a decade since the market value of mammalian-cell-derived protein therapeutics surpassed that of those produced from E. coli. A common characteristic of recent antibody products is the relatively large dose required for effective therapy, demanding larger quantities for the treatment of a given disease. This, coupled with the broadening repertoire of protein drugs, has rapidly expanded the quantity needed for clinical applications. The increasing demand for protein therapeutics has not been met exclusively by construction of new manufacturing plants and increasing total volume capacity. More - portantly the productivity of cell culture processes has been driven upward by an order of magnitude in the past decade.
Author : John Colter
Publisher : Elsevier
ISBN 13 : 0323142737
Total Pages : 747 pages
Book Rating : 4.3/5 (231 download)
Download or read book The Molecular Biology of Viruses written by John Colter and published by Elsevier. This book was released on 2012-12-02 with total page 747 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Molecular Biology of Viruses is a collection of manuscripts presented at the Third Annual International Symposium of the Molecular Biology of Viruses, held in the University of Alberta, Canada on June 27-30, 1966, sponsored by the Faculty of Medicine of the University of Alberta. This book is organized into eight parts encompassing 36 chapters that emphasize the biosynthetic steps involved in polymer duplication. The first two parts explore the specialized processes of the cycle of virulent and temperate bacteriophage multiplication. These parts also deal with the production, regulation of development, and selectivity of these bacteriophages. The subsequent two parts look into the heterozygosity, mutation, structure, function, and mode of infection of single-stranded DNA and RNA bacteriophages. The discussions then shift to the biological and physicochemical aspects, biosynthesis, translation, genetics, and replication of mammalian DNA and RNA viruses. The concluding parts describe the homology, interaction, functions, mechanism of transformation, metabolism, and carcinogenic activity of oncogenic viruses. This book is of great benefit to biochemists, biophysicists, geneticists, microbiologists, and virologists.
Author : Terri Grodzicker
Publisher : Symposium Proceedings
ISBN 13 : 9781621822868
Total Pages : 426 pages
Book Rating : 4.8/5 (228 download)
Download or read book Chromosome Segregation and Structure written by Terri Grodzicker and published by Symposium Proceedings. This book was released on 2018-07-31 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 82nd Cold Spring Harbor Symposium focused on Chromosome Segregation & Structure and addressed the enormous progress in our understanding of the nature and behavior of chromosomes during the life cycle of the cell. It is rare to find such a wide-ranging perspective on this topic in one volume and this collection of papers will be valuable to investigators interested in many aspects of cell biology, genetics, and cancer. The topics covered at the meeting included: Meiosis; Mitosis; Chromosome Segregation; Centrosomes and Centrioles; Ploidy, Chromosome Segregation Errors & Disease; Asymmetric Cell Division; Nuclear Architecture; Chromosome Structure and Condensation; Sister Chromatid Cohesion; Genome Stability; and Germ Cells. Numerous speakers participated in interviews during the course of the Symposium week and transcripts of those discussions and the Dorcas Cummings lecture by David Page are included.
Author : Terri Grodzicker
Publisher : John Donald
ISBN 13 : 9781621820253
Total Pages : 0 pages
Book Rating : 4.8/5 (22 download)
Download or read book The Biology of Plants written by Terri Grodzicker and published by John Donald. This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants are integral to human wellbeing, and many species have been domesticated for over ten thousand years. Evidence of plant scientific investigation and classification can be found in ancient texts from cultures around the world (Chinese, Indian, Greco-Roman, Muslim etc.), while early modern botany can be traced to the late 15th and early 16th centuries in Europe. During the past several decades plant biology has been revolutionized first by molecular biology and then by the genomic era. The model organism Arabidopsis thaliana has proved an invaluable tool for investigation into fundamental processes in plant biology, many of which share commonalities with animal biology. Plant-specific processes from reproduction to immunity and second messengers have also yielded to extensive investigation. With the genomes of more than thirty plant species now available and many more planned in the near future, the impact on our understanding of plant evolution and biology continues to grow. Our increased ability to engineer plant species to a variety of ends may provide novel solutions to ensure adequate and reliable food production and renewable energy even as climate change impacts our environment. The decision to focus the 2012 Symposium on plant science reflects the enormous research progress achieved in recent years, and is intended to provide a broad synthesis of the current state of the field, setting the stage for future discoveries and application. This is the first Symposium in this historic series focused exclusively on the botanical sciences. Plants are integral to human wellbeing, and many species have been domesticated for over ten thousand years. Evidence of plant scientific investigation and classification can be found in ancient texts from cultures around the world (Chinese, Indian, Greco-Roman, Muslim etc.), while early modern botany can be traced to the late 15th and early 16th centuries in Europe. During the past several decades plant biology has been revolutionized first by molecular biology and then by the genomic era. The model organism Arabidopsis thaliana has proved an invaluable tool for investigation into fundamental processes in plant biology, many of which share commonalities with animal biology. Plant-specific processes from reproduction to immunity and second messengers have also yielded to extensive investigation. With the genomes of more than thirty plant species now available and many more planned in the near future, the impact on our understanding of plant evolution and biology continues to grow. Our increased ability to engineer plant species to a variety of ends may provide novel solutions to ensure adequate and reliable food production and renewable energy even as climate change impacts our environment. The decision to focus the 2012 Symposium on plant science reflects the enormous research progress achieved in recent years, and is intended to provide a broad synthesis of the current state of the field, setting the stage for future discoveries and application. This is the first Symposium in this historic series focused exclusively on the botanical sciences.
Author : Laura L. Mays Hoopes
Publisher :
ISBN 13 : 9780359413966
Total Pages : 161 pages
Book Rating : 4.4/5 (139 download)
Download or read book Opening Doors written by Laura L. Mays Hoopes and published by . This book was released on 2019 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: A dual biography of Joan Steitz and Jennifer Doudna, two women who combined successful home lives with successful careers in science.
