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Download or read book Symposium on Regulated Intramembrane Proteolysis written by and published by . This book was released on 2007 with total page 5 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Willem G. Annaert
Publisher :
ISBN 13 :
Total Pages : 124 pages
Book Rating : 4.:/5 (613 download)
Download or read book Regulated Intramembrane Proteolysis written by Willem G. Annaert and published by . This book was released on 2009 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Qiuyue Chen
Publisher :
ISBN 13 :
Total Pages : 88 pages
Book Rating : 4.:/5 (919 download)
Download or read book Regulation of Expression and Regulated Intramembrane Proteolysis of CREB3L1 written by Qiuyue Chen and published by . This book was released on 2013 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Sajal Chakraborti
Publisher : Springer
ISBN 13 : 9811061416
Total Pages : 668 pages
Book Rating : 4.8/5 (11 download)
Download or read book Pathophysiological Aspects of Proteases written by Sajal Chakraborti and published by Springer. This book was released on 2017-11-15 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the multifaceted field of protease in the cellular environment and focuses on the recently elucidated functions of complex proteolytic systems in physiology and pathophysiology. Given the breadth and depth of information covered in the respective contributions, the book will be immensely useful for researchers working to identify targets for drug development. Multidisciplinary in scope, the book bridges the gap between fundamental and translational research, with applications in the biomedical and pharmaceutical industry, making it a thought-provoking read for basic and applied scientists engaged in biomedical research. Proteases represent one of the largest and most diverse families of enzymes known, and we now know that they are involved in every aspect of a given organism’s life functions. Under physiological conditions, proteases are regulated by their endogenous inhibitors. However, when the activity of proteases is not correctly regulated, disease processes such as tumour progression, vascular remodelling, atherosclerotic plaque progression, ulcer, rheumatoid arthritis, Alzheimer’s disease and inflammation can result. Many infective microorganisms require proteases for replication or use them as virulence factors, which has facilitated the development of protease-targeted therapies for a variety of parasitic diseases.
Author : Debomoy K. Lahiri
Publisher : Bentham Science Publishers
ISBN 13 : 1608054950
Total Pages : 342 pages
Book Rating : 4.6/5 (8 download)
Download or read book Advances in Alzheimer's Research written by Debomoy K. Lahiri and published by Bentham Science Publishers. This book was released on 2013-11-05 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer’s disease (AD) is currently recognized as an untreatable, progressive, degenerative and terminal disease that is globally afflicting an estimated 36 million people and this number is growing in an unabated and frightening manner. Advances in Alzheimer Research, provides researchers with an integrated approach to AD academic literature ranging from basic to advanced clinical research. The series highlights the latest information in order to unravel the origin, pathogenesis and prevention of AD. The purpose of this book series is, therefore, to capture and discuss both, improvements towards the diagnosis and potential treatment of AD by established and novel strategies. This first volume of the series provides an important mechanism to bring individuals having a variety of scientific interests and expertise under one roof to specifically focus on AD and related dementias. This volume presents articles on beta amyloid protein targets as well as research on secretase enzyme systems among other topics that deal with AD therapy.
Author : Sajal Chakraborti
Publisher : Springer
ISBN 13 : 9811031622
Total Pages : 516 pages
Book Rating : 4.8/5 (11 download)
Download or read book Proteases in Human Diseases written by Sajal Chakraborti and published by Springer. This book was released on 2017-07-13 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book bridges the gap between fundamental research and biomedical and pharmacological applications on proteases. It represents a comprehensive overview of the multifaceted field of proteases in cellular environment and highlights the recently elucidated functions of complex proteolytic systems in different diseases. Several established investigators have elucidated the crucial role of proteases in biological processes, including how proteolytic function and regulation can be combined to develop new strategies of therapeutic interventions. Proteases form one of the largest and most diverse families of enzymes known. It is now clear that proteases are involved in every aspect of life functions of an organism. Under physiological conditions, proteases are regulated by their endogenous inhibitors; however, when the activity of proteases is not regulated appropriately, disease processes can result in. So, there is absolute need for a stringent control of proteolytic activities in cells and tissues. Dysregulation of proteases may cause derangement of cellular signalling network resulting in different pathophysiological conditions such as vascular remodelling, atherosclerotic plaque progression, ulcer and rheumatoid arthritis, Alzheimer disease, cancer metastasis, tumor progression and inflammation. Additionally, many infective microorganisms require proteases for replication or use proteases as virulence factors, which have facilitated the development of protease-targeted therapies for a variety of parasitic diseases.
Author :
Publisher : Academic Press
ISBN 13 : 0128122641
Total Pages : 552 pages
Book Rating : 4.1/5 (281 download)
Download or read book Neurotrophins written by and published by Academic Press. This book was released on 2017-02-15 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurotrophins, the latest volume in the Vitamins and Hormones series first published in 1943, and the longest-running serial published by Academic Press, provides up-to-date information on crystal structures and basic structural studies on neurotrophins and their receptors, neurotrophin functions, and the biological actions of neurotrophins related to clinical conditions and disease. Each volume is thoroughly reviewed and focuses on a single molecule or disease that is related to vitamins or hormones, with the topic broadly interpreted to include related substances such as transmitters, cytokines, growth factors, and others. - Provides cutting-edge reviews concerning the molecular and cellular biology of vitamins and hormones - Contains expertise from world-renowned contributors - Focuses on a single molecule or disease that is related to vitamins or hormones, with the topic broadly interpreted to include related substances such as transmitters, cytokines, growth factors, and others - Presents in-depth, current information from the molecular to clinical level
Author : I. S. Kulaev
Publisher : Academic Press
ISBN 13 : 1483272494
Total Pages : 538 pages
Book Rating : 4.4/5 (832 download)
Download or read book Environmental Regulation of Microbial Metabolism written by I. S. Kulaev and published by Academic Press. This book was released on 2014-05-12 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental Regulation of Microbial Metabolism contains the proceedings of the Federation of European Microbiological Societies Symposium held in Pushchino, USSR, on June 1-7, 1983. The symposium provided a forum for reviewing the environmental regulation of the metabolism of autotrophic and heterotrophic microorganisms; regulation of the biogenesis of cell walls and other structures in prokaryotic and eukaryotic microorganisms; and regulation of the secretion of macromolecules and transport of ions and solutes across microbial membranes. Comprised of 52 chapters, this book begins with an overview of some aspects of environmental regulation of microbial phosphorus metabolism, followed by a discussion on the role of covalent interconversion of enzymes in the regulation of microbial metabolism. Subsequent chapters explore the role and regulation of inorganic pyrophosphatase in bacteria; the central metabolism of pseudomonads degrading xenobiotics; the role of nickel enzymes in anaerobic metabolism; and the oxidation of aromatic compounds by microalgae. The book also considers carbon metabolism in phototrophic bacteria under different conditions of growth, along with the transport of solutes and metabolites in prokaryotes and eukaryotes. This monograph will be helpful to a wide range of specialists in the fields of biochemistry, physiology, molecular biology, and biotechnology.
Author : Abraham Fisher
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 380558282X
Total Pages : 366 pages
Book Rating : 4.8/5 (55 download)
Download or read book Alzheimer's and Parkinson's Diseases written by Abraham Fisher and published by Karger Medical and Scientific Publishers. This book was released on 2007 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue is a dedicated supplement published in addition to the regular issues of 'Neurodegenerative Diseases' containing congress abstracts. 'Neurodegenerative Diseases' is a well-respected, international peer-reviewed journal in Neurology. Supplement issues are included in the subscription.
Author :
Publisher :
ISBN 13 :
Total Pages : 2454 pages
Book Rating : 4.:/5 (319 download)
Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Author :
Publisher :
ISBN 13 :
Total Pages : 968 pages
Book Rating : 4.6/5 (251 download)
Download or read book Seikagaku written by and published by . This book was released on 2003 with total page 968 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ralph A. Nixon
Publisher : Springer Science & Business Media
ISBN 13 : 1441967877
Total Pages : 775 pages
Book Rating : 4.4/5 (419 download)
Download or read book Cytoskeleton of the Nervous System written by Ralph A. Nixon and published by Springer Science & Business Media. This book was released on 2011-02-04 with total page 775 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph begins with a general description of the cytoskeleton in axonal development and pathology and then moves to more detailed descriptions of particular components, including microtubules and associated proteins, neurofilaments and interacting proteins, actin and its binding proteins, and glial fibrillary acidic protein. The later chapters focus on the functional significance of the neuronal cytoskeleton in axonal transport and its regulation in health and disease states. The Cytoskeleton of the Nervous System will encourage further development of unifying principles and stimulate new conceptual and technical approaches toward a better understanding of cytoskeleton functions in health and disease.
Author : Shihori Tanabe
Publisher : Springer Nature
ISBN 13 : 3031129741
Total Pages : 163 pages
Book Rating : 4.0/5 (311 download)
Download or read book Cancer Stem Cell Markers and Related Network Pathways written by Shihori Tanabe and published by Springer Nature. This book was released on 2023-02-02 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book entitled “Cancer Stem Cell Markers and Related Network Path-ways” is about cancer stem cell (CSC) markers and the molecular network pathways. CSCs play an important role in the cancer drug resistance, metastasis and recurrence. Epithelial-mesenchymal transition (EMT) is closely related to CSC phenotype. This book covers various aspects of the molecular networks related to CSCs including the important phenotypic change such as EMT. Readers will discover the importance of the identification of CSC markers and EMT-related molecules in CSC network pathways. The CSC signaling pathways and EMT molecular network pathways attract researchers in the field to define the cancer therapeutic targets. Cancer environment is important in the acquisition of CSC phenotype in cells. The revealing of this CSC mystery is across 7 chapters. The topic of this book is particularly relevant to research in the field of cancer and stem cells, as well as the network pathways. We hope that this book helps the readers to be interested in understanding why the CSC concept is important and attractive.
Author :
Publisher :
ISBN 13 :
Total Pages : 570 pages
Book Rating : 4.F/5 ( download)
Download or read book Microbiology Abstracts written by and published by . This book was released on 1986 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Roberto Pérez Torrado
Publisher :
ISBN 13 : 9781071617328
Total Pages : 332 pages
Book Rating : 4.6/5 (173 download)
Download or read book The Unfolded Protein Response written by Roberto Pérez Torrado and published by . This book was released on 2022 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is divided in six section covering the most experimental approaches involved in the study of the unfolded protein response (UPR) pathway. Chapters detail determination of unfolded protein levels, methods to study UPR signal transmission, analysing the outcomes of the UPR pathway activation, UPR studies in mammalian models, UPR in alternative models, and UPR and disease. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, The Unfolded Protein Response: Methods and Protocols aims to describe key methods and approaches used in the study of the UPR pathway and its complex cellular implications. Chapter 6 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Author : Barbara E. Ehrlich
Publisher :
ISBN 13 :
Total Pages : 275 pages
Book Rating : 4.:/5 (64 download)
Download or read book Organellar Ion Channels and Transporters written by Barbara E. Ehrlich and published by . This book was released on 1996 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 414 pages
Book Rating : 4.3/5 (91 download)
Download or read book Book of Abstracts written by and published by . This book was released on 2003 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt:
