Supercritical Fluids In Chromatography And Extraction

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Analysis with Supercritical Fluids: Extraction and Chromatography

Author : Bernd Wenclawiak
Publisher : Springer Science & Business Media
ISBN 13 : 3642774741
Total Pages : 225 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Analysis with Supercritical Fluids: Extraction and Chromatography by : Bernd Wenclawiak

Download or read book Analysis with Supercritical Fluids: Extraction and Chromatography written by Bernd Wenclawiak and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of supercritical fluids in analytical chemistry is still grow ing. More and more analysts are discovering the favorable advan tages for a number of applications. Especially supercritical fluid extraction (SFE) has attracted a lot of interest in recent years due to its simplicity. Supercritical fluid chromatography (SFC) has become better established and the development of this technique has been accelerated by the many applications with capillary col umns which have been published in the literature. At first SFC equipment was based on instruments commonly used for liquid chromatography, and the first commercial in struments were derived from this technology. However, capillary columns can be much more easily interfaced to gas chromatogra phy equipment especially to the detectors commonly used for Oc. Many stationary phases both for packed micro columns and capillary columns have been designed for SFC purposes extending this technology to LC and OC. The most common fluid applied in SFC and SFE is carbon dioxide. The advantages of supercritical CO , such as having dif 2 fusivity like a gas and solvating power depending on temperature and pressure, are also valid for other fluids and modified fluids. Both properties are valuable for sample extraction and extraction selectivity.

Supercritical Fluid Extraction and its Use in Chromatographic Sample Preparation

Author : S.A. Westwood
Publisher : Springer Science & Business Media
ISBN 13 : 9401121648
Total Pages : 180 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Supercritical Fluid Extraction and its Use in Chromatographic Sample Preparation by : S.A. Westwood

Download or read book Supercritical Fluid Extraction and its Use in Chromatographic Sample Preparation written by S.A. Westwood and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: by Professor D. E. Games, Mass Spectrometry Research Unit, University College of Swansea Sample preparation can be viewed as occupying a Cinderella role in analytical science. However, the quality of sample preparation plays a key role in high In the past decade, there has been quality analysis and deserves higher stature. considerable interest in the use of supercritical fluid extraction (SFE) as an alternative to conventional procedures for the preparation of samples for ana lysis. The driving force for this development is the need for automated, sim pler, faster, non-destructive and selective methods for extraction, preferably using non-toxic extraction media which are easily disposed of. Utilization of supercritical fluids for extraction fulfils these requirements because of their unique physical chemical properties and usually low toxicity. Selectivity can be achieved by suitable selection of pressure (density), temperature and modi fier conditions which enable solvating power to be varied. The high diffusivity of supercritical fluids provides rapid sample penetration and extraction. Use of fluids with low critical temperatures enables extraction to be conducted under mild thermal conditions ensuring that thermally labile compounds do not decompose. The technique can be used off-line, and the extracts analysed by appropriate techniques, or it can be used on-line, by coupling with a variety of chromatographic techniques. These can then, if necessary, be coupled fur ther with spectroscopic techniques, such as Fourier transform infrared, ultra violet or mass spectrometry, to provide specific identification or structural information.

Supercritical Fluid Extraction

Author : Mark McHugh
Publisher : Elsevier
ISBN 13 : 0080518176
Total Pages : 523 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Supercritical Fluid Extraction by : Mark McHugh

Download or read book Supercritical Fluid Extraction written by Mark McHugh and published by Elsevier. This book was released on 2013-10-22 with total page 523 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supercritical Fluid Extraction is a technique in which CO2 is used under extremely high pressure to separate solution (e.g., removing caffeine from coffee). Separations is basic to all process industries and supercritical fluid extraction is a specific type which is receiving a high level of attention. The book will combine basic fundamentals with industrial applications. The second edition has been expanded and updated and includes new chapters on chromatography and food processing. "...this is an excellent book which is both instructive and amusing to read. Its true value is neatly summarised in one of the closing sentences: 'We have supplied you with the guidelines and criteria which you can now apply when considering supercritical fluids for your own needs.'' - Chemistry in Britain, February 1995

Applications of Supercritical Fluids in Industrial Analysis

Author : J.R. Dean
Publisher : Springer Science & Business Media
ISBN 13 : 940112146X
Total Pages : 238 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Applications of Supercritical Fluids in Industrial Analysis by : J.R. Dean

Download or read book Applications of Supercritical Fluids in Industrial Analysis written by J.R. Dean and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: The continued search for rapid, efficient and cost-effective means of analytical measurement has introduced supercritical fluids into the field of analytical chemistry. Two areas are common: supercritical fluid chroma tography and supercritical fluid extraction. Both seek to exploit the unique properties of a gas at temperatures and pressures above the critical point. The most common supercritical fluid is carbon dioxide, employed because of its low critical temperature (31 °C), inertness, purity, non-toxicity and cheapness. Alternative supercritical fluids are also used and often in conjunction with modifiers. The combined gas-like mass transfer and liquid-like solvating characteristics have been used for improved chroma tographic separation and faster sample preparation. Supercritical fluid chromatography (SFC) is complementary to gas chro matography ( GC) and high performance liquid chromatography (HPLC), providing higher efficiency than HPLC, together with the ability to analyse thermally labile and high molecular weight analytes. Both packed and open tubular columns can be employed, providing the capability to analyse a wide range of sample types. In addition, flame ionization detection can be used, thus providing 'universal' detection.

Supercritical Fluid Chromatography

Author : Colin F. Poole
Publisher : Elsevier
ISBN 13 : 0128093676
Total Pages : 574 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Supercritical Fluid Chromatography by : Colin F. Poole

Download or read book Supercritical Fluid Chromatography written by Colin F. Poole and published by Elsevier. This book was released on 2017-02-16 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supercritical fluid chromatography (SFC) is a rapidly developing laboratory technique for the separation and identification of compounds in mixtures. Significant improvements in instrumentation have rekindled interest in SFC in recent years and enhanced its standing in the scientific community. Many scientists are familiar with column liquid chromatography and its strengths and weaknesses, but the possibilities brought to the table by SFC are less well-known and are underappreciated. Supercritical Fluid Chromatography is a thorough and encompassing reference that defines the concept of contemporary practice in SFC and how it should be implemented in laboratory science. Given the changes that have taken place in SFC, this book presents contemporary aspects and applications of the technique and introduces SFC as a natural solution in the larger field of separation science. The focus on state-of-the-art instrumental SFC distinguishes this work as the go-to reference work for those interested in implementing the technique at an advanced level. - Edited and authored by world-leading chromatography experts - Provides comprehensive coverage of SFC in a single source - Extensive referencing facilitates identification of key research developments - More than 200 figures and tables aid in the retention of key concepts

Green Sustainable Process for Chemical and Environmental Engineering and Science

Author : Rajender Boddula
Publisher : Elsevier
ISBN 13 : 0128198516
Total Pages : 242 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Green Sustainable Process for Chemical and Environmental Engineering and Science by : Rajender Boddula

Download or read book Green Sustainable Process for Chemical and Environmental Engineering and Science written by Rajender Boddula and published by Elsevier. This book was released on 2021-11-17 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Green Sustainable Process for Chemical and Environmental Engineering and Science: Switchable Solvents explores the preparation, properties, chemical processes and applications of this class of green solvents. The book provides an in-depth overview on the area of switchable solvents in various industrial applications, focusing on the purification and extraction of chemical compounds utilizing green chemistry protocols that include liquid-liquid, solid-liquid, liquid-gas and lipids separation technologies. In addition, it includes recent advances in greener extraction and separation processes. This book will be an invaluable guide to students, professors, scientists and R&D industrial specialists working in the field of sustainable chemistry, organic, analytical, chemical engineering, environmental and pharmaceutical sciences. - Provides a broad overview of switchable solvents in sustainable chemical processes - Compares the use of switchable solvents as greener solvents over conventional solvents - Outlines eco-friendly organic synthesis and chemical processes using switchable solvents - Lists various industrial separations/extraction processes using switchable solvents

Analytical Supercritical Fluid Extraction

Author : Maria D. Luque de Castro
Publisher : Springer Science & Business Media
ISBN 13 : 3642786731
Total Pages : 332 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Analytical Supercritical Fluid Extraction by : Maria D. Luque de Castro

Download or read book Analytical Supercritical Fluid Extraction written by Maria D. Luque de Castro and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in analytical chemistry have turned it into a virtually unrecognizable science compared to a few decades ago, when it lagged behind other sciences and techniques. However, advances in analytical science have been far from universal: while innovations in instrumentation and data acquisition and processing systems have reached unprecedented levels thanks to parallel breakthroughs in computer science and chemo metrics, progress in preliminary operations has been much slower despite their importance to analytical results. Thus, such clear trends in analytical process development as automation and miniaturization have not reached preliminary operations to the same extent, even though this area is pro bably in the greatest need. Improvement in preliminary operations is thus an urgent goal of analytical chemistry on the verge of the twenty first century. Increased R&D endeavours and manufacture of commercially available automatic equipment for implementation of the wide variety of operations that separate the uncollected, unmeasured, untreated sample from the signal measuring step are thus crucial on account of the wide variability of such operations, which precludes development of all-purpose equipment, and the complexity of some, particularly relating to solid samples. Supercritical fluid extraction opens up interesting prospects in this context and is no doubt an effective approach to automatioI1 and mini aturization in the preliminary steps of the analytical process. The dramatic developments achieved in its short life are atypical in many respects.

Packed Column SFC

Author : T A Berger
Publisher : Royal Society of Chemistry
ISBN 13 : 1847551602
Total Pages : 268 pages
Book Rating : 4.8/5 (475 download)

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Book Synopsis Packed Column SFC by : T A Berger

Download or read book Packed Column SFC written by T A Berger and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Packed Column SFC is the third title to be published in this series and has been produced as a result of the dramatic re-emergence, in the last three years, of packed column instrumentation. This has led to a redefinition of the technique and an urgent need for a practical guide that deals with its subtleties. This book fulfils that need and deals exclusively with packed column SFC. It places the emphasis on understanding the underlying chemistry in order to perform rapid, systematic optimizations and provides many practical tips to help the new user avoid problems unique to SFC. It also proposes a detailed scheme for method development and provides lists of prioritized guidelines. The book clears up some of the confusion that surrounds the analytical use of supercritical fluids and assists the user in understanding the power and utility of this technique. Detailed chapters cover the most promising new application areas for packed column SFC, which are often overlooked in the mainstream chromatography literature. Like the other books in this popular series, Packed Column SFC will prove an invaluable guide and is essential reading for graduates, postgraduates and researchers with interests in pharmaceuticals, agricultural chemistry, small polar drug molecules, chiral analysis, environmental chemistry, and chromatography/instrumentation.

Biophysical Characterization of Proteins in Developing Biopharmaceuticals

Author : Damian J. Houde
Publisher : Elsevier
ISBN 13 : 0444641742
Total Pages : 588 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Biophysical Characterization of Proteins in Developing Biopharmaceuticals by : Damian J. Houde

Download or read book Biophysical Characterization of Proteins in Developing Biopharmaceuticals written by Damian J. Houde and published by Elsevier. This book was released on 2019-11-13 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biophysical Characterization of Proteins in Developing Biopharmaceuticals, Second Edition, presents the latest on the analysis and characterization of the higher-order structure (HOS) or conformation of protein based drugs. Starting from the very basics of protein structure, this book explains the best way to achieve this goal using key methods commonly employed in the biopharmaceutical industry. This book will help today's industrial scientists plan a career in this industry and successfully implement these biophysical methodologies. This updated edition has been fully revised, with new chapters focusing on the use of chromatography and electrophoresis and the biophysical characterization of very large biopharmaceuticals. In addition, best practices of applying statistical analysis to biophysical characterization data is included, along with practical issues associated with the concept of a biopharmaceutical's developability and the technical decision-making process needed when dealing with biophysical characterization data. - Presents basic protein characterization methods and tools applicable to (bio)pharmaceutical research and development - Highlights the capabilities and limitations of each technique - Discusses the underlining science of each tool - Empowers industrial biophysical chemists by providing a roadmap for applying biophysical tools - Outlines the needs for new characterization and analytical tools in the biopharmaceutical industry

Analytical Supercritical Fluid Extraction Techniques

Author : E.D. Ramsey
Publisher : Springer Science & Business Media
ISBN 13 : 9401149488
Total Pages : 449 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Analytical Supercritical Fluid Extraction Techniques by : E.D. Ramsey

Download or read book Analytical Supercritical Fluid Extraction Techniques written by E.D. Ramsey and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past decade supercritical fluid extration (SFE) has attracted considerable attention as a sample preparation procedure in analytical chemistry. The successful implementation of this technique can lead to improved sample throughput, more efficient recovery of analytes, cleaner extracts, economic replacement of halogenated solvents and a high level of automation, compared to conventional sample preparation procedures. This book provides an overview of basic principles of SFE as well as in-depth reviews of both on- and off-line SFE methods. The on-line coupling of SFE with both chromatographic and spectroscopics techniques has been the subject of a great deal of research effort and is dealt with in detail. Newer developments, such as off-line SFE of solid and liquid matrices, are starting to attract a great deal of interest, and the coverage of these areas will prove of particular value to the analytical chemist. The international team of authors has illustrated these topics with many `state-of-the-art' applications, and each chapter provides a comprehensive list of references. For the convenience of the reader, an appendix which contains pressure conversion scales and supercritical fluid carbon dioxide density tables appears at the end of the book. The volume's extensive coverage of both on-line and off-line extraction will be particularly useful to analytical chemists, in a wide range of environments, seeking to develop high quality, simple and robust SFE methods.

Supercritical Fluids

Author : E. Kiran
Publisher : Springer Science & Business Media
ISBN 13 : 9401139296
Total Pages : 602 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Supercritical Fluids by : E. Kiran

Download or read book Supercritical Fluids written by E. Kiran and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supercritical fluids are neither gas nor liquid, but can be compressed gradually from low to high density and they are therefore interesting and important as tunable solvents and reaction media in the chemical process industry. By adjusting the density the properties of these fluids can be customised and manipulated for a given process - physical or chemical transformation. Separation and processing using supercritical solvents such as CO2 are currently on-line commercially in the food, essential oils and polymer industries. Many agencies and industries are considering the use of supercritical water for waste remediation. Supercritical fluid chromatography represents another, major analytical application. Significant advances have recently been made in materials processing, ranging from particle formation to the creation of porous materials. The chapters in this book provide tutorial accounts of topical areas centred around: (1) phase equilibria, thermodynamics and equations of state; (2) critical behaviour, crossover effects; (3) transport and interfacial properties; (4) molecular modelling, computer simulation; (5) reactions, spectroscopy; (6) phase separation kinetics; (7) extractions; (8) applications to polymers, pharmaceuticals, natural materials and chromatography; (9) process scale-up.

Gas Extraction

Author : Gerd Brunner
Publisher : Springer Science & Business Media
ISBN 13 : 3662073803
Total Pages : 396 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Gas Extraction by : Gerd Brunner

Download or read book Gas Extraction written by Gerd Brunner and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Application of compressed gases as solvents has found widespread interest within the scientific community. Its processes have industrial applications. Gas Extraction deals with the possibilities of supercritical gases as solvents for separation processes. The volume combines physico-chemical aspects with chemical engineering methods. The text generalizes as far as possible, and treats examples in detail. Gas Extraction covers, for the first time, the subject in textbook form. Most of the examples provide new results that will be helpful for practicing scientists, engineers, and students who want to make use of the techniques.

Unified Chromatography

Author : J. F. Parcher
Publisher :
ISBN 13 :
Total Pages : 272 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Unified Chromatography by : J. F. Parcher

Download or read book Unified Chromatography written by J. F. Parcher and published by . This book was released on 2000 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here, authors specializing in different branches of chromatography--including gas chromatography, supercritical fluid chromatography, and high-pressure liquid chromatography--describe their fields while drawing out connections with other branches.

Analytical Techniques in the Oil and Gas Industry for Environmental Monitoring

Author : Melissa N. Dunkle
Publisher : John Wiley & Sons
ISBN 13 : 1119523303
Total Pages : 464 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Analytical Techniques in the Oil and Gas Industry for Environmental Monitoring by : Melissa N. Dunkle

Download or read book Analytical Techniques in the Oil and Gas Industry for Environmental Monitoring written by Melissa N. Dunkle and published by John Wiley & Sons. This book was released on 2020-09-01 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thorough introduction to environmental monitoring in the oil and gas industry Analytical Techniques in the Oil and Gas Industry for Environmental Monitoring examines the analytical side of the oil and gas industry as it also provides an overall introduction to the industry. You’ll discover how oil and natural gas are sourced, refined, and processed. You can learn about what’s produced from oil and natural gas, and why evaluating these sourced resources is important. The book discusses the conventional analyses for oil and natural gas feeds, along with their limitations. It offers detailed descriptions of advanced analytical techniques that are commercially available, plus explanations of gas and oil industry equipment and instrumentation. You’ll find technique descriptions supplemented with a list of references as well as with real-life application examples. With this book as a reference, you can prepare to apply specific analytical methods in your organization’s lab environment. Analytical Techniques can also serve as your comprehensive resource on key techniques in the characterization of oil and gas samples, within both refinery and environmental contexts. Understand of the scope of oil and gas industry techniques available Consider the benefits and limitations of each available process Prepare for applying analytical techniques in your lab See real examples and a list of references for each technique Read descriptions of off-line analytics, as well as on-line and process applications As a chemist, engineer, instructor, or student, this book will also expand your awareness of the role these techniques have in environmental monitoring and environmental impact assessments.

Supercritical Fluid Extraction of Nutraceuticals and Bioactive Compounds

Author : Jose L. Martinez
Publisher : CRC Press
ISBN 13 : 1420006517
Total Pages : 424 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Supercritical Fluid Extraction of Nutraceuticals and Bioactive Compounds by : Jose L. Martinez

Download or read book Supercritical Fluid Extraction of Nutraceuticals and Bioactive Compounds written by Jose L. Martinez and published by CRC Press. This book was released on 2007-11-28 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Enhanced concern for the quality and safety of food products, increased preference for natural products, and stricter regulations on the residual level of solvents, all contribute to the growing use of supercritical fluid technology as a primary alternative for the extraction, fractionation, and isolation of active ingredients. As a solvent-free p

Modern Supercritical Fluid Chromatography

Author : Larry M. Miller
Publisher : John Wiley & Sons
ISBN 13 : 1118948394
Total Pages : 416 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Modern Supercritical Fluid Chromatography by : Larry M. Miller

Download or read book Modern Supercritical Fluid Chromatography written by Larry M. Miller and published by John Wiley & Sons. This book was released on 2019-12-12 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explains why modern supercritical fluid chromatography (SFC) is the leading "green" analytical and purification separations technology. Modern supercritical fluid chromatography (SFC) is the leading method used to analyze and purify chiral and achiral chemical compounds, many of which are pharmaceuticals, pharmaceutical candidates, and natural products including cannabis-related compounds. This book covers current SFC instrumentation as it relates to greater robustness, better reproducibility, and increased analytical sensitivity. Modern Supercritical Fluid Chromatography: Carbon Dioxide Containing Mobile Phases covers the history, instrumentation, method development and applications of SFC. The authors provided readers with an overview of analytical and preparative SFC equipment, stationary phases, and mobile phase choices. Topics covered include: Milestones of Supercritical Fluid Chromatography; Physical Properties of Supercritical Fluids; Instrumentation for SFC; Detection in SFC; Achiral SFC Method Development; Chiral SFC Method Development; and Preparative Scale SFC. The book also includes highlights of modern applications of SFC in the final chapters—namely pharmaceuticals, consumer products, foods, polymers, petroleum-related mixtures, and cannabis—and discusses the future of SFC. Provides a clear explanation of the physical and chemical properties of supercritical fluids, which gives the reader a better understanding of the basis for improved performance in SFC compared to HPLC and GC Describes the advantages of SFC as a green alternative to HPLC and GC for the analysis of both polar, water-soluble, and non-polar analytes Details both achiral and chiral SFC method development, including modifiers, additives, the impact of temperature and pressure, and stationary phase choices Details why SFC is the premier modern preparative chromatographic technique used to purify components of mixtures for subsequent uses, both from performance and economic perspectives Covers numerous detectors, with an emphasis on SFC-MS, SFC-UV, and SFC-ELSD (evaporative light scattering detection) Describes the application of SFC to numerous high-value application areas Modern Supercritical Fluid Chromatography: Carbon Dioxide Containing Mobile Phases will be of great interest to professionals, students, and professors involved in analytical, bioanalytical, separations science, medicinal, petroleum, and environmental chemistries. It will also appeal to pharmaceutical scientists, natural-product scientists, food and consumer-products scientists, chemical engineers, and managers in these areas.

Handbook of Advanced Chromatography /Mass Spectrometry Techniques

Author : Michal Holcapek
Publisher : Elsevier
ISBN 13 : 0128117338
Total Pages : 522 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Handbook of Advanced Chromatography /Mass Spectrometry Techniques by : Michal Holcapek

Download or read book Handbook of Advanced Chromatography /Mass Spectrometry Techniques written by Michal Holcapek and published by Elsevier. This book was released on 2017-09-07 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Advanced Chromatography /Mass Spectrometry Techniques is a compendium of new and advanced analytical techniques that have been developed in recent years for analysis of all types of molecules in a variety of complex matrices, from foods to fuel to pharmaceuticals and more. Focusing on areas that are becoming widely used or growing rapidly, this is a comprehensive volume that describes both theoretical and practical aspects of advanced methods for analysis. Written by authors who have published the foundational works in the field, the chapters have an emphasis on lipids, but reach a broader audience by including advanced analytical techniques applied to a variety of fields. Handbook of Advanced Chromatography / Mass Spectrometry Techniques is the ideal reference for those just entering the analytical fields covered, but also for those experienced analysts who want a combination of an overview of the techniques plus specific and pragmatic details not often covered in journal reports. The authors provide, in one source, a synthesis of knowledge that is scattered across a multitude of literature articles. The combination of pragmatic hints and tips with theoretical concepts and demonstrated applications provides both breadth and depth to produce a valuable and enduring reference manual. It is well suited for advanced analytical instrumentation students as well as for analysts seeking additional knowledge or a deeper understanding of familiar techniques. - Includes UHPLC, HILIC, nano-liquid chromatographic separations, two-dimensional LC-MS (LCxLC), multiple parallel MS, 2D-GC (GCxGC) methodologies for lipids analysis, and more - Contains both practical and theoretical knowledge, providing core understanding for implementing modern chromatographic and mass spectrometric techniques - Presents chapters on the most popular and fastest-growing new techniques being implemented in diverse areas of research