Applying an Implementation Science Approach to Genomic Medicine

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Author :
Publisher : National Academies Press
ISBN 13 : 0309437792
Total Pages : 137 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Applying an Implementation Science Approach to Genomic Medicine by : National Academies of Sciences, Engineering, and Medicine

Download or read book Applying an Implementation Science Approach to Genomic Medicine written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-07-06 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although it is becoming increasingly more common for clinicians to use genomic data in their practices for disease prevention, diagnosis, and treatment, the process of integrating genomic data into the practice of medicine has been a slow and challenging one. Some of the major barriers impeding the incorporation of new genomic technology into clinical practice are: the difficulty of changing routine medical practices to account for the use of genetic testing, the limited knowledge of patients and providers about genomic medicine, assessing sufficient evidence to support the use of genetic tests, privacy and data security issues, and uncertainty about reimbursement. The field of implementation science may be able to provide insights concerning efficient ways to incorporate genomic applications into routine clinical practice. The focus of implementation science studies is to identify integration bottlenecks and optimal approaches for a given setting and ultimately to promote the up-take of research findings. To explore the potential of implementation science to improve the integration of genomics into medicine, the National Academies of Sciences, Engineering, and Medicine held a workshop in Washington, DC, in November 2015. Participants explored the challenges and opportunities of integrating genomic advances into the clinic through the lens of implementation science. This report summarizes the presentations and discussions from the workshop.

Implementation Research in Health

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Publisher : World Health Organization
ISBN 13 : 9241506210
Total Pages : 69 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Implementation Research in Health by : David H. Peters

Download or read book Implementation Research in Health written by David H. Peters and published by World Health Organization. This book was released on 2013 with total page 69 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in implementation research is growing, largely in recognition of the contribution it can make to maximizing the beneficial impact of health interventions. As a relatively new and, until recently, rather neglected field within the health sector, implementation research is something of an unknown quantity for many. There is therefore a need for greater clarity about what exactly implementation research is, and what it can offer. This Guide is designed to provide that clarity. Intended to support those conducting implementation research, those with responsibility for implementing programs, and those who have an interest in both, the Guide provides an introduction to basic implementation research concepts and language, briefly outlines what it involves, and describes the many opportunities that it presents. The main aim of the Guide is to boost implementation research capacity as well as demand for implementation research that is aligned with need, and that is of particular relevance to health systems in low- and middle-income countries (LMICs). Research on implementation requires the engagement of diverse stakeholders and multiple disciplines in order to address the complex implementation challenges they face. For this reason, the Guide is intended for a variety of actors who contribute to and/or are impacted by implementation research. This includes the decision-makers responsible for designing policies and managing programs whose decisions shape implementation and scale-up processes, as well as the practitioners and front-line workers who ultimately implement these decisions along with researchers from different disciplines who bring expertise in systematically collecting and analyzing information to inform implementation questions. The opening chapters (1-4) make the case for why implementation research is important to decision-making. They offer a workable definition of implementation research and illustrate the relevance of research to problems that are often considered to be simply administrative and provide examples of how such problems can be framed as implementation research questions. The early chapters also deal with the conduct of implementation research, emphasizing the importance of collaboration and discussing the role of implementers in the planning and designing of studies, the collection and analysis of data, as well as in the dissemination and use of results. The second half of the Guide (5-7) detail the various methods and study designs that can be used to carry out implementation research, and, using examples, illustrates the application of quantitative, qualitative, and mixed-method designs to answer complex questions related to implementation and scale-up. It offers guidance on conceptualizing an implementation research study from the identification of the problem, development of research questions, identification of implementation outcomes and variables, as well as the selection of the study design and methods while also addressing important questions of rigor.

Implementation Science at a Glance

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Author :
Publisher : Government Printing Office
ISBN 13 : 0160950694
Total Pages : 47 pages
Book Rating : 4.1/5 (69 download)

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Book Synopsis Implementation Science at a Glance by : National Cancer Institute (U.S.)

Download or read book Implementation Science at a Glance written by National Cancer Institute (U.S.) and published by Government Printing Office. This book was released on 2019-04-01 with total page 47 pages. Available in PDF, EPUB and Kindle. Book excerpt: While many effective interventions can reduce cancer risk, incidence, and death, as well as enhance quality of life, they are of no benefit if they cannot be delivered to those in need. In the face of increasingly dynamic and resource-constrained conditions, implementation science plays a critical role in delivering cancer control practices. This 30-page workbook was written by members of the NCI (National Cancer Institute) implementation Science team and reviewed by nearly 100 public health practitioners and implementation science researchers. Through summaries of key theories, methods, and models, the guide shows how greater use of implementation science can support the effective adoption of evidence-based interventions. Case studies illustrate how practitioners are successfully applying implementation science in their cancer control programs

The State of Quality Improvement and Implementation Research

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Publisher : National Academies Press
ISBN 13 : 0309179653
Total Pages : 108 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The State of Quality Improvement and Implementation Research by : Institute of Medicine

Download or read book The State of Quality Improvement and Implementation Research written by Institute of Medicine and published by National Academies Press. This book was released on 2007-10-01 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Institute of Medicine (IOM) workshop "The Conduct of Health Care Quality Improvement and Implementation Research" was held on May 24-25, 2007, in Irvine, CA. The purpose of this workshop was to gain a better understanding of what is known and not known about quality improvement and implementation research. Experts were asked to identify current methods and best practices as well as areas where future efforts should be concentrated to propel the field. As with its previous workshop, the Forum on the Science of Health Care Quality Improvement and Implementation invited speakers from other disciplines to share their experiences in their respective fields. Although many disciplines are relevant to this topic, not all views could be incorporated because of workshop time constraints, but will be incorporated in the forum's future activities. The State of Quality Improvement and Implementation Research: Expert Views, Workshop Summary describes and summarizes workshop presentations and discussions.

Summary of Research Results Implementation

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Author :
Publisher :
ISBN 13 :
Total Pages : 148 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Summary of Research Results Implementation by : Joint Highway Research Project (Ind.)

Download or read book Summary of Research Results Implementation written by Joint Highway Research Project (Ind.) and published by . This book was released on 1995 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Patient Safety

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Publisher :
ISBN 13 :
Total Pages : 526 pages
Book Rating : 4.7/5 (54 download)

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Book Synopsis Advances in Patient Safety by : Kerm Henriksen

Download or read book Advances in Patient Safety written by Kerm Henriksen and published by . This book was released on 2005 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: v. 1. Research findings -- v. 2. Concepts and methodology -- v. 3. Implementation issues -- v. 4. Programs, tools and products.

Finding What Works in Health Care

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Publisher : National Academies Press
ISBN 13 : 0309164257
Total Pages : 267 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Finding What Works in Health Care by : Institute of Medicine

Download or read book Finding What Works in Health Care written by Institute of Medicine and published by National Academies Press. This book was released on 2011-07-20 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.

Facilitating the Implementation of Research Findings

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Publisher : Transportation Research Board
ISBN 13 : 9780309057219
Total Pages : 28 pages
Book Rating : 4.0/5 (572 download)

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Book Synopsis Facilitating the Implementation of Research Findings by : Tora K. Bikson

Download or read book Facilitating the Implementation of Research Findings written by Tora K. Bikson and published by Transportation Research Board. This book was released on 1996 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Intervention Research

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Publisher : Springer Publishing Company
ISBN 13 : 0826109586
Total Pages : 496 pages
Book Rating : 4.8/5 (261 download)

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Book Synopsis Intervention Research by : Bernadette Mazurek Melnyk, PhD, RN, CPNP/ PMHNP, FNAP, FAAN

Download or read book Intervention Research written by Bernadette Mazurek Melnyk, PhD, RN, CPNP/ PMHNP, FNAP, FAAN and published by Springer Publishing Company. This book was released on 2012-04-23 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: 2012 First Place AJN Book of the Year Award Winner in Nursing Research! "This is a resource for success and should be a part of any researcher's library."--Doody's Medical Reviews This book is a practical, user-friendly guide for health care researchers across multiple disciplines who are involved in intervention research. It provides all of the essential elements needed for understanding how to design, conduct, analyze, and fund intervention studies that are replicable and can withstand the scrutiny of the Institutional Review Board and peer review. Developed from an annual continuing education workshop on intervention studies conducted by Dr. Melnyk, this text is the most comprehensive body of information available on this topic. Contributors address the design of interventions that are ethically considerate and sensitive to culture, race/ethnicity, and gender, minimizing threats to external and internal validity, measurement, and budgeting. The guide explores such implementation issues as subject recruitment and retention, data management, and specialized settings, cost analysis, and explaining intervention effects. The text also guides readers in writing grant applications that fund , and addresses how to move intervention study findings into the real world. A unique addition to the book is the availability of digital examples of progress reports, final reports, and research grant applications that have received funding from the National Institutes of Health and other relevant organizations. This text is a valuable resource for all health care professionals conducting research and for doctoral students in health care studies. Key Features: Presents the essential tools for designing, conducting, analyzing, and funding intervention studies Designed for use by health care professionals conducting intervention research Provides comprehensive, accessible guidelines for doctoral students across all health care disciplines Instructs readers on writing grant applications that fund Includes digital examples of funded research grants, progress reports, and final reports

Social Isolation and Loneliness in Older Adults

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Author :
Publisher : National Academies Press
ISBN 13 : 0309671035
Total Pages : 317 pages
Book Rating : 4.3/5 (96 download)

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Book Synopsis Social Isolation and Loneliness in Older Adults by : National Academies of Sciences, Engineering, and Medicine

Download or read book Social Isolation and Loneliness in Older Adults written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-05-14 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Social isolation and loneliness are serious yet underappreciated public health risks that affect a significant portion of the older adult population. Approximately one-quarter of community-dwelling Americans aged 65 and older are considered to be socially isolated, and a significant proportion of adults in the United States report feeling lonely. People who are 50 years of age or older are more likely to experience many of the risk factors that can cause or exacerbate social isolation or loneliness, such as living alone, the loss of family or friends, chronic illness, and sensory impairments. Over a life course, social isolation and loneliness may be episodic or chronic, depending upon an individual's circumstances and perceptions. A substantial body of evidence demonstrates that social isolation presents a major risk for premature mortality, comparable to other risk factors such as high blood pressure, smoking, or obesity. As older adults are particularly high-volume and high-frequency users of the health care system, there is an opportunity for health care professionals to identify, prevent, and mitigate the adverse health impacts of social isolation and loneliness in older adults. Social Isolation and Loneliness in Older Adults summarizes the evidence base and explores how social isolation and loneliness affect health and quality of life in adults aged 50 and older, particularly among low income, underserved, and vulnerable populations. This report makes recommendations specifically for clinical settings of health care to identify those who suffer the resultant negative health impacts of social isolation and loneliness and target interventions to improve their social conditions. Social Isolation and Loneliness in Older Adults considers clinical tools and methodologies, better education and training for the health care workforce, and dissemination and implementation that will be important for translating research into practice, especially as the evidence base for effective interventions continues to flourish.

Implementation Research Toolkit

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Publisher :
ISBN 13 : 9789241506960
Total Pages : 175 pages
Book Rating : 4.5/5 (69 download)

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Book Synopsis Implementation Research Toolkit by : World Health Organization

Download or read book Implementation Research Toolkit written by World Health Organization and published by . This book was released on 2014 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: Implementation research is conducted within routine systems and real life settings, removed from the controlled settings associated with other types of scientific research. This toolkit was designed to help people learn a standard process that would lead to results that could be compared across regions and countries. It is designed to help identify system bottlenecks and the stakeholders to be involved, formulate appropriate research questions, conduct the research and develop a plan for implementing the study results. Who can use this toolkit? Health care service providers Program staff Researchers Decision-makers Finance and administration officers Media Learn how to: Identify barriers to implementation and formulate the research question Make your case for funding Set up a study design and appropriate methodologies Plan the project (budget, personnel, timelines, monitoring and evaluation) Collect, analyze and present research information Develop a dissemination plan Monitor and evaluate your research projectOver 200 researchers, academics, disease control program managers, policy-makers, health administrators, communication scientists and journalists contributed to test and evaluate the toolkit. Major funding was provided by USAID, with additional support from the Implementation Research Platform at the World Health Organization.

Dissemination and Implementation Research in Health

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Publisher : Oxford University Press
ISBN 13 : 019068321X
Total Pages : 545 pages
Book Rating : 4.1/5 (96 download)

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Book Synopsis Dissemination and Implementation Research in Health by : Ross C. Brownson

Download or read book Dissemination and Implementation Research in Health written by Ross C. Brownson and published by Oxford University Press. This book was released on 2017-12-05 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fifteen to twenty years is how long it takes for the billions of dollars of health-related research to translate into evidence-based policies and programs suitable for public use. Over the past 15 years, an exciting science has emerged that seeks to narrow the gap between the discovery of new knowledge and its application in public health, mental health, and health care settings. Dissemination and implementation (D & I) research seeks to understand how to best apply scientific advances in the real world, by focusing on pushing the evidence-based knowledge base out into routine use. To help propel this crucial field forward, leading D & I scholars and researchers have collaborated to put together this volume to address a number of key issues, including : how to evaluate the evidence base on effective interventions; which strategies will produce the greatest impact; how to design an appropriate study; and how to track a set of essential outcomes. D & I studies must also take into account the barriers to uptake of evidence-based interventions in the communities where people live their lives and the social service agencies, hospitals, and clinics where they receive care. The challenges of moving research to practice and policy are universal, and future progress calls for collaborative partnerships and cross-country research. The fundamental tenet of D & I research--taking what we know about improving health and putting it into practice--must be the highest priority. This book is nothing less than a roadmap that will have broad appeal to researchers and practitioners across many disciplines. [Ed.].

Principles and Practice of Clinical Research

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Publisher : Elsevier
ISBN 13 : 0080489567
Total Pages : 447 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Principles and Practice of Clinical Research by : John I. Gallin

Download or read book Principles and Practice of Clinical Research written by John I. Gallin and published by Elsevier. This book was released on 2011-04-28 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers. *Incorporates new chapters on Managing Conflicts of Interest in Human Subjects Research, Clinical Research from the Patient's Perspective, The Clinical Researcher and the Media, Data Management in Clinical Research, Evaluation of a Protocol Budget, Clinical Research from the Industry Perspective, and Genetics in Clinical Research *Addresses the vast opportunities for translation of basic science observations to the bedside through clinical research*Delves into data management and addresses how to collect data and use it for discovery*Contains valuable, up-to-date information on how to obtain funding from the federal government

Evaluating AIDS Prevention Programs

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Publisher : National Academies Press
ISBN 13 : 030904281X
Total Pages : 391 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Evaluating AIDS Prevention Programs by : National Research Council

Download or read book Evaluating AIDS Prevention Programs written by National Research Council and published by National Academies Press. This book was released on 1991-02-01 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: With insightful discussion of program evaluation and the efforts of the Centers for Disease Control, this book presents a set of clear-cut recommendations to help ensure that the substantial resources devoted to the fight against AIDS will be used most effectively. This expanded edition of Evaluating AIDS Prevention Programs covers evaluation strategies and outcome measurements, including a realistic review of the factors that make evaluation of AIDS programs particularly difficult. Randomized field experiments are examined, focusing on the use of alternative treatments rather than placebo controls. The book also reviews nonexperimental techniques, including a critical examination of evaluation methods that are observational rather than experimentalâ€"a necessity when randomized experiments are infeasible.

Improving Patient Care

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Publisher : John Wiley & Sons
ISBN 13 : 111852599X
Total Pages : 525 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Improving Patient Care by : Richard Grol

Download or read book Improving Patient Care written by Richard Grol and published by John Wiley & Sons. This book was released on 2013-03-18 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: As innovations are constantly being developed within health care, it can be difficult both to select appropriate new practices and technologies and to successfully adopt them within complex organizations. It is necessary to understand the consequences of introducing change, how to best implement new procedures and techniques, how to evaluate success and to improve the quality of patient care. This comprehensive guide allows you to do just that. Improving Patient Care, 2nd edition provides a structure for professionals and change agents to implement better practices in health care. It helps health professionals, managers, policy makers and researchers to assess new techniques and select and implement change in their organizations. This new edition includes recent evidence and further coverage on patient safety and patient centred strategies for change. Written by an international expert author team, Improving Patient Care is an established standard text for postgraduate students of health policy, health services and health management. The strong author team are global professors involved in managing research and development in the field of quality improvement, evidence-based practice and guidelines, quality assessment and indicators to improve patient outcomes through receiving appropriate healthcare.

Cochrane Handbook for Systematic Reviews of Interventions

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Publisher : Wiley
ISBN 13 : 9780470699515
Total Pages : 672 pages
Book Rating : 4.6/5 (995 download)

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Book Synopsis Cochrane Handbook for Systematic Reviews of Interventions by : Julian P. T. Higgins

Download or read book Cochrane Handbook for Systematic Reviews of Interventions written by Julian P. T. Higgins and published by Wiley. This book was released on 2008-11-24 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Healthcare providers, consumers, researchers and policy makers are inundated with unmanageable amounts of information, including evidence from healthcare research. It has become impossible for all to have the time and resources to find, appraise and interpret this evidence and incorporate it into healthcare decisions. Cochrane Reviews respond to this challenge by identifying, appraising and synthesizing research-based evidence and presenting it in a standardized format, published in The Cochrane Library (www.thecochranelibrary.com). The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane intervention reviews. Written in a clear and accessible format, it is the essential manual for all those preparing, maintaining and reading Cochrane reviews. Many of the principles and methods described here are appropriate for systematic reviews applied to other types of research and to systematic reviews of interventions undertaken by others. It is hoped therefore that this book will be invaluable to all those who want to understand the role of systematic reviews, critically appraise published reviews or perform reviews themselves.

The Application of Content Analysis in Nursing Science Research

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Author :
Publisher : Springer Nature
ISBN 13 : 3030301990
Total Pages : 115 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis The Application of Content Analysis in Nursing Science Research by : Helvi Kyngäs

Download or read book The Application of Content Analysis in Nursing Science Research written by Helvi Kyngäs and published by Springer Nature. This book was released on 2019-10-31 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides principles on content analysis and its application into development of nursing theory. It offers clear guidance to students, lecturers and researchers to gain a deeper understanding of the method of content analysis, its implementation into their own research and criteria of trustworthiness evaluation. The book is written in user-friendly language with provided research examples and cases, and the content is illustrated by figures and tables. The authors offer their expertise in providing a well thought through explanation of content analysis in didactical style, which will enhance university education. The book includes highly experienced researchers who have published articles on content analysis and the trustworthiness of the method with more than 10 000 citations. Divided into two parts, this book explores the application of content analysis into nursing science. The first part presents the philosophical position of content analysis, inductive and deductive methods of using content analysis, trustworthiness of the method, and ethical consideration of using content analysis. The second part informs on the theory development based on content analysis, conceptualization of the concepts of content analysis into generation of items and instrument development, and statistical testing of a hypothetical model. The last chapter shows a new approach to using content analysis in systematic reviews and quality evaluation of methodology within systematic review process. The book is an essential tool for nursing science, providing instruction on key methodological elements in order to provide rigorously conducted empirical research for clinical practice and nursing education.