Studies on Biomarkers and New Targets in Aging Research in Iran

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Publisher :
ISBN 13 : 9783030561543
Total Pages : 0 pages
Book Rating : 4.5/5 (615 download)

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Book Synopsis Studies on Biomarkers and New Targets in Aging Research in Iran by : Paul C. Guest

Download or read book Studies on Biomarkers and New Targets in Aging Research in Iran written by Paul C. Guest and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Middle East is known as the cradle of civilization. It was the crossroads of ancient empires and the birthplace of major world religions. Today it is the center of many world issues due to its economic, religious and political importance. Although it has lagged behind many other regions of the world in medicinal research, this has increased dramatically in recent years with increasing numbers of relevant publications and the country of Iran has spearheaded this progress. Much of the research has focused on increasing our understanding of the aging process and attempting to identify biomarkers and natural products to improve the human healthspan. This book provides a comprehensive overview of the research conducted in the Middle East on the health benefits of curcumin, a phytochemical derived from the famous spice turmeric. Hundreds of studies have now been published describing the health benefits of this spice. The importance of this research is exemplified by poor data regarding health and longevity as only 0.08% of the population in Iran consists of individuals over 90 years of age. This is approximately 10 times lower than the percentage of this same age group in the United Kingdom and the United States of America and almost 20 times lower than that in Japan. This book presents a series of reviews and meta-studies describing research which has resulted in identification potential new biomarkers and drug targets for age-related disorders. All of the studies have focussed on the testing of curcumin and related products, which have already shown some promising leads in age-related conditions such as heart-disease, diabetes, cognitive impairment and cancer. The authors in this series come from different centers and cities of Iran, including Mashhad, Tehran, Isfahan, Ahvaz, Birjand, Quchan and Yazd, and many of the chapters feature collaborations with other countries of the Middle East and throughout the world, including Brazil, Italy, Mexico, Oman, Poland, Switzerland, the United Kingdom and the United States of America. This underscores the emergence of the Middle East into this arena of research. The book will be of high interest to scientific and clinical researchers in the subject of aging and age-related disease, and to physicians and pharmaceutical company scientists since it gives insights into the latest strategies, biomarkers and targets involved in the mechanism of action of curcumin to promote healthy aging. It will also provide important information on disease mechanisms related to age-related disorders, as each chapter will be presented in the context of specific chronic diseases. .

Studies on Biomarkers and New Targets in Aging Research in Iran

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Author :
Publisher : Springer Nature
ISBN 13 : 3030561534
Total Pages : 376 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Studies on Biomarkers and New Targets in Aging Research in Iran by : Paul C. Guest

Download or read book Studies on Biomarkers and New Targets in Aging Research in Iran written by Paul C. Guest and published by Springer Nature. This book was released on 2021-07-31 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Middle East is known as the cradle of civilization. It was the crossroads of ancient empires and the birthplace of major world religions. Today it is the center of many world issues due to its economic, religious and political importance. Although it has lagged behind many other regions of the world in medicinal research, this has increased dramatically in recent years with increasing numbers of relevant publications and the country of Iran has spearheaded this progress. Much of the research has focused on increasing our understanding of the aging process and attempting to identify biomarkers and natural products to improve the human healthspan. This book provides a comprehensive overview of the research conducted in the Middle East on the health benefits of curcumin, a phytochemical derived from the famous spice turmeric. Hundreds of studies have now been published describing the health benefits of this spice. The importance of this research is exemplified by poor data regarding health and longevity as only 0.08% of the population in Iran consists of individuals over 90 years of age. This is approximately 10 times lower than the percentage of this same age group in the United Kingdom and the United States of America and almost 20 times lower than that in Japan. This book presents a series of reviews and meta-studies describing research which has resulted in identification potential new biomarkers and drug targets for age-related disorders. All of the studies have focussed on the testing of curcumin and related products, which have already shown some promising leads in age-related conditions such as heart-disease, diabetes, cognitive impairment and cancer. The authors in this series come from different centers and cities of Iran, including Mashhad, Tehran, Isfahan, Ahvaz, Birjand, Quchan and Yazd, and many of the chapters feature collaborations with other countries of the Middle East and throughout the world, including Brazil, Italy, Mexico, Oman, Poland, Switzerland, the United Kingdom and the United States of America. This underscores the emergence of the Middle East into this arena of research. The book will be of high interest to scientific and clinical researchers in the subject of aging and age-related disease, and to physicians and pharmaceutical company scientists since it gives insights into the latest strategies, biomarkers and targets involved in the mechanism of action of curcumin to promote healthy aging. It will also provide important information on disease mechanisms related to age-related disorders, as each chapter will be presented in the context of specific chronic diseases.

Studies on Biomarkers and New Targets in Aging Research in Iran

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Author :
Publisher : Springer
ISBN 13 : 9783030561529
Total Pages : 381 pages
Book Rating : 4.5/5 (615 download)

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Book Synopsis Studies on Biomarkers and New Targets in Aging Research in Iran by : Paul C. Guest

Download or read book Studies on Biomarkers and New Targets in Aging Research in Iran written by Paul C. Guest and published by Springer. This book was released on 2021-06-20 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Middle East is known as the cradle of civilization. It was the crossroads of ancient empires and the birthplace of major world religions. Today it is the center of many world issues due to its economic, religious and political importance. Although it has lagged behind many other regions of the world in medicinal research, this has increased dramatically in recent years with increasing numbers of relevant publications and the country of Iran has spearheaded this progress. Much of the research has focused on increasing our understanding of the aging process and attempting to identify biomarkers and natural products to improve the human healthspan. This book provides a comprehensive overview of the research conducted in the Middle East on the health benefits of curcumin, a phytochemical derived from the famous spice turmeric. Hundreds of studies have now been published describing the health benefits of this spice. The importance of this research is exemplified by poor data regarding health and longevity as only 0.08% of the population in Iran consists of individuals over 90 years of age. This is approximately 10 times lower than the percentage of this same age group in the United Kingdom and the United States of America and almost 20 times lower than that in Japan. This book presents a series of reviews and meta-studies describing research which has resulted in identification potential new biomarkers and drug targets for age-related disorders. All of the studies have focussed on the testing of curcumin and related products, which have already shown some promising leads in age-related conditions such as heart-disease, diabetes, cognitive impairment and cancer. The authors in this series come from different centers and cities of Iran, including Mashhad, Tehran, Isfahan, Ahvaz, Birjand, Quchan and Yazd, and many of the chapters feature collaborations with other countries of the Middle East and throughout the world, including Brazil, Italy, Mexico, Oman, Poland, Switzerland, the United Kingdom and the United States of America. This underscores the emergence of the Middle East into this arena of research. The book will be of high interest to scientific and clinical researchers in the subject of aging and age-related disease, and to physicians and pharmaceutical company scientists since it gives insights into the latest strategies, biomarkers and targets involved in the mechanism of action of curcumin to promote healthy aging. It will also provide important information on disease mechanisms related to age-related disorders, as each chapter will be presented in the context of specific chronic diseases.

Anticancer Spices

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Publisher : CRC Press
ISBN 13 : 1040155049
Total Pages : 236 pages
Book Rating : 4.0/5 (41 download)

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Book Synopsis Anticancer Spices by : Hardeep Singh Tuli

Download or read book Anticancer Spices written by Hardeep Singh Tuli and published by CRC Press. This book was released on 2024-10-03 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Humankind has used a variety of spices to flavor food for centuries. However, the chemistry and potential health benefits of these herbs have become clearer only rather recently. Numerous studies performed during the past decades have revealed several advantageous properties of bioactive constituents of various spices, including their anticancer effects. This edited collection summarizes diverse types of anticancer activities of compounds derived from some well-known spices, describing the anticancer mechanisms behind their action and highlighting molecular targets and cellular signaling pathways. It acquaints the reader with the potential anticancer activities of agents contained in laurel, oregano, thyme, rosemary, basil, dill, parsley, and several other common spices. These molecular entities could probably be considered as lead structures for further design of more efficient anticancer drugs in the future.

Exploring the Effects of Diet on the Development and Prognosis of Multiple Sclerosis (MS)

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Author :
Publisher : Springer Nature
ISBN 13 : 9819746736
Total Pages : 235 pages
Book Rating : 4.8/5 (197 download)

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Book Synopsis Exploring the Effects of Diet on the Development and Prognosis of Multiple Sclerosis (MS) by : Hamdan Hamdan

Download or read book Exploring the Effects of Diet on the Development and Prognosis of Multiple Sclerosis (MS) written by Hamdan Hamdan and published by Springer Nature. This book was released on with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Curcumin-Based Nanomedicines as Cancer Therapeutics

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Publisher : Elsevier
ISBN 13 : 0443154139
Total Pages : 492 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Curcumin-Based Nanomedicines as Cancer Therapeutics by : Amirhossein Sahebkar

Download or read book Curcumin-Based Nanomedicines as Cancer Therapeutics written by Amirhossein Sahebkar and published by Elsevier. This book was released on 2024-02-21 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Curcumin-Based Nanomedicines as Cancer Therapeutics presents a consistent and thorough overview of nanocurcumin applications in cancer treatments. It brings together the novel applications of nanocurcumin in biological milieu as well as helps readers to define the major gaps in knowledge that can lead to significant scientific discoveries.Nanocurcumin have been widely explored for treatment of various cancers, however the scientific literature is inconsistent in style and structure and scattered across many sources. By providing an explicit account on vital aspects on nanocurcumin-based anticancer delivery approaches and discussing the perspectives of the technologies explored so far based upon the findings outlined, the book offers updated and in-depth knowledge on the topic in one single source written by global leading experts.In addition, the book aims to stimulate the interest of the academic researchers, industrial scientists, businessmen and young scholars to address key multidisciplinary challenges faced by nanotechnologists to foster the desired collaboration among biologists, chemists, physicists, engineers, and clinicians to find proper and efficient new cancer treatments. Discusses the complete journey of curcumin delivery from fundamental to most recent anticancer applications using nanotechnology Provides in-depth knowledge on novel anticancer application of nanocurcumin in biological milieu Presents reliable and updated information for researchers on nanocurcumin-based anticancer targeted drug delivery

Aptamers Engineered Nanocarriers for Cancer Therapy

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Publisher : Woodhead Publishing
ISBN 13 : 0323855768
Total Pages : 558 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Aptamers Engineered Nanocarriers for Cancer Therapy by : Prashant Kesharwani

Download or read book Aptamers Engineered Nanocarriers for Cancer Therapy written by Prashant Kesharwani and published by Woodhead Publishing. This book was released on 2022-09-25 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aptamers Engineered Nanocarriers for Cancer Therapy details the selection technologies, biological characteristics, and clinical uses of aptamer-based nano agents for cancer therapeutics. The book helps facilitate speedy solutions for some of the problems pertaining to the manufacture of nano-aptamers – such as toxicity, thermal stability, cost efficiency, tumor penetration and blood stability. Key chapters cover cell-SELEX technology for aptamer selection, mechanisms of multi-drug resistance of cancer, the relevance of aptamers as anticancer therapies, as well as the broad range of aptamer-functionalized nanostructures available. This book provides exciting insights into this relatively new approach to cancer therapeutics, and will be of interest to materials scientists, biomedical engineers, molecular biologists, biochemists and clinical scientists, with a focus on cancer therapy. Reviews the mechanisms behind multi-drug resistance (MDR) in cancer and how aptamer-mediated novel therapeutic agents and strategies can facilitate MDR reversal Covers a range of aptamers engineered nanostructures, including PLGA nanoparticles, silica nanoparticles, quantum dots, nucleic acid aptamers, and more Discusses the challenges associated with using aptamers as cancer therapeutics and how this translates into clinical use

Reviews on New Drug Targets in Age-Related Disorders

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Publisher : Springer Nature
ISBN 13 : 3030550354
Total Pages : 274 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Reviews on New Drug Targets in Age-Related Disorders by : Paul C. Guest

Download or read book Reviews on New Drug Targets in Age-Related Disorders written by Paul C. Guest and published by Springer Nature. This book was released on 2021-03-16 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging is an inevitable part of life, and is becoming a worldwide social, economic and health problem due to the fact that an increasing proportion of individuals in the advanced age category have a higher probability of developing age-related disorders. New therapeutic approaches are still in need to decrease or slow the effects of such diseases in this aging society. Advances in ‘omic technologies such as genomics, transcriptomics, proteomics and metabolomics have significantly advanced our understanding of diseases in multiple medical areas. It is hoped that emerging hits from these analyses might be prioritized for further screening as potential novel drug targets for increasing the human healthspan in line with the lifespan, which will in turn lead to new therapeutic strategies and drug development projects by the pharmaceutical industry. This new book presents a series of reviews describing studies which have resulted in the identification of potential new drug targets for age-related disorders. Much of this information has come from ‘omic comparisons of healthy and disease states or from testing the effects of potential new therapeutic approaches. Each chapter will be presented in the context of specific chronic diseases or different therapeutic strategies, providing important information on disease mechanisms related to the aging process. This book will be of interest to researchers in the areas of aging and chronic disease, as well as clinical scientists, physicians, and major drug companies. With contributors from Australia, Brazil, Canada, France, Germany, India, Iran, Iraq, South Africa, South Korea, Thailand, Ukraine, United Kingdom, United States of America, Uruguay and Vietnam, this is a timely follow up to Guest’s previous book Reviews on New Drug Targets in Age-Related Disorders.

Blood Biomarkers of Neurodegenerative Diseases

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 288976284X
Total Pages : 273 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Blood Biomarkers of Neurodegenerative Diseases by : Thomas K. Karikari

Download or read book Blood Biomarkers of Neurodegenerative Diseases written by Thomas K. Karikari and published by Frontiers Media SA. This book was released on 2022-05-31 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Reviews on New Drug Targets in Age-Related Disorders

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Author :
Publisher : Springer Nature
ISBN 13 : 303042667X
Total Pages : 340 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Reviews on New Drug Targets in Age-Related Disorders by : Paul C. Guest

Download or read book Reviews on New Drug Targets in Age-Related Disorders written by Paul C. Guest and published by Springer Nature. This book was released on 2020-04-17 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging is an inevitable part of life and is becoming a worldwide social, economic and health problem. This is mainly due to the fact that the increasing proportion of individuals in the advanced age category have a higher probability of developing age-related disorders, such as type II diabetes mellitus, cardiovascular disorders, sarcopenia, and neurodegenerative conditions. New therapeutic approaches are still needed to decrease or slow the effects of such diseases. Advances in -omic technologies, such as genomics, transcriptomics, proteomics and metabolomics, have significantly advanced our understanding of disease in multiple medical areas, as the analysis of multiple molecular networks has simultaneously provided a more integrated view of disease pathways. It is hoped that emerging hits from these analyses might be prioritized for further screening as potential novel drug targets for increasing the human healthspan in line with the lifespan. In turn, this will lead to new therapeutic strategies as well as drug development projects by the pharmaceutical industry. This book presents a series of reviews describing studies that have resulted in identification of new potential drug targets for age-related disorders. Much of this information has come from -omic comparisons of healthy and disease states or from testing the effects of new therapeutic approaches. Authored by experts from around the globe, each chapter is presented in the context of specific chronic diseases or therapeutic strategies. This book is designed for researchers in the areas of aging and chronic disease, as well as clinical scientists, physicians and stakeholders in major drug companies.

Families Caring for an Aging America

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Publisher : National Academies Press
ISBN 13 : 0309448093
Total Pages : 367 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Families Caring for an Aging America by : National Academies of Sciences, Engineering, and Medicine

Download or read book Families Caring for an Aging America written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-11-08 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Family caregiving affects millions of Americans every day, in all walks of life. At least 17.7 million individuals in the United States are caregivers of an older adult with a health or functional limitation. The nation's family caregivers provide the lion's share of long-term care for our older adult population. They are also central to older adults' access to and receipt of health care and community-based social services. Yet the need to recognize and support caregivers is among the least appreciated challenges facing the aging U.S. population. Families Caring for an Aging America examines the prevalence and nature of family caregiving of older adults and the available evidence on the effectiveness of programs, supports, and other interventions designed to support family caregivers. This report also assesses and recommends policies to address the needs of family caregivers and to minimize the barriers that they encounter in trying to meet the needs of older adults.

Environmental Epigenetics

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Author :
Publisher : Springer
ISBN 13 : 1447166787
Total Pages : 327 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Environmental Epigenetics by : L. Joseph Su

Download or read book Environmental Epigenetics written by L. Joseph Su and published by Springer. This book was released on 2015-05-18 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.

Plant-derived Bioactives

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Publisher : Springer Nature
ISBN 13 : 9811517614
Total Pages : 619 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Plant-derived Bioactives by : Mallappa Kumara Swamy

Download or read book Plant-derived Bioactives written by Mallappa Kumara Swamy and published by Springer Nature. This book was released on 2020-05-11 with total page 619 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants produce a vast number of bioactive compounds with different chemical scaffolds, which modulate a diverse range of molecular targets and are used as drugs for treating numerous diseases. Most present-day medicines are derived either from plant compounds or their derivatives, and plant compounds continue to offer limitless reserves for the discovery of new medicines. While different classes of plant compounds, like phenolics, flavonoids, saponins and alkaloids, and their potential pharmacological applications are currently being explored, their curative mechanisms are yet to be understood in detail. This book is divided into 2 volumes and offers detailed information on plant-derived bioactive compounds, including recent research findings. Volume 1, Plant-derived Bioactives: Chemistry and Mode of Action, discusses the chemistry of highly valued plant bioactive compounds and their mode of actions at the molecular level. Volume 2, Plant-derived Bioactives: Production, Properties and Therapeutic Applications, explores the sources, biosynthesis, production, biological properties and therapeutic applications of plant bioactives. Given their scope, these books are valuable resources for members of the scientific community wishing to further explore various medicinal plants and the therapeutic applications of their bioactive compounds. They appeal to scholars, teachers and scientists involved in plant product research, and facilitate the development of innovative new drugs.

Cutaneous Aging

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Author :
Publisher : Columbia University Press
ISBN 13 :
Total Pages : 678 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis Cutaneous Aging by : Albert M. Kligman

Download or read book Cutaneous Aging written by Albert M. Kligman and published by Columbia University Press. This book was released on 1988 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Trends in biomarkers for neurodegenerative diseases: Current research and future perspectives

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832518001
Total Pages : 273 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Trends in biomarkers for neurodegenerative diseases: Current research and future perspectives by : Suman Dutta

Download or read book Trends in biomarkers for neurodegenerative diseases: Current research and future perspectives written by Suman Dutta and published by Frontiers Media SA. This book was released on 2023-03-23 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nutrition and Healthy Aging in the Community

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Publisher : National Academies Press
ISBN 13 : 0309253101
Total Pages : 152 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Nutrition and Healthy Aging in the Community by : Institute of Medicine

Download or read book Nutrition and Healthy Aging in the Community written by Institute of Medicine and published by National Academies Press. This book was released on 2012-06-15 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: The U.S. population of older adults is predicted to grow rapidly as "baby boomers" (those born between 1946 and 1964) begin to reach 65 years of age. Simultaneously, advancements in medical care and improved awareness of healthy lifestyles have led to longer life expectancies. The Census Bureau projects that the population of Americans 65 years of age and older will rise from approximately 40 million in 2010 to 55 million in 2020, a 36 percent increase. Furthermore, older adults are choosing to live independently in the community setting rather than residing in an institutional environment. Furthermore, the types of services needed by this population are shifting due to changes in their health issues. Older adults have historically been viewed as underweight and frail; however, over the past decade there has been an increase in the number of obese older persons. Obesity in older adults is not only associated with medical comorbidities such as diabetes; it is also a major risk factor for functional decline and homebound status. The baby boomers have a greater prevalence of obesity than any of their historic counterparts, and projections forecast an aging population with even greater chronic disease burden and disability. In light of the increasing numbers of older adults choosing to live independently rather than in nursing homes, and the important role nutrition can play in healthy aging, the Institute of Medicine (IOM) convened a public workshop to illuminate issues related to community-based delivery of nutrition services for older adults and to identify nutrition interventions and model programs. Nutrition and Healthy Aging in the Community summarizes the presentations and discussions prepared from the workshop transcript and slides. This report examines nutrition-related issues of concern experienced by older adults in the community including nutrition screening, food insecurity, sarcopenic obesity, dietary patterns for older adults, and economic issues. This report explores transitional care as individuals move from acute, subacute, or chronic care settings to the community, and provides models of transitional care in the community. This report also provides examples of successful intervention models in the community setting, and covers the discussion of research gaps in knowledge about nutrition interventions and services for older adults in the community.

Non-coding RNA as Prognostic and Diagnostic Biomarkers in Thoracic Oncology

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889746313
Total Pages : 191 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Non-coding RNA as Prognostic and Diagnostic Biomarkers in Thoracic Oncology by : Desi Shang

Download or read book Non-coding RNA as Prognostic and Diagnostic Biomarkers in Thoracic Oncology written by Desi Shang and published by Frontiers Media SA. This book was released on 2022-03-09 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: