Studies From The Department Of Pathology Of The Shanghai Science Institute

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Handbook of the Biology of Aging

Author : Nicolas Musi
Publisher : Academic Press
ISBN 13 : 0124116205
Total Pages : 576 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Handbook of the Biology of Aging by : Nicolas Musi

Download or read book Handbook of the Biology of Aging written by Nicolas Musi and published by Academic Press. This book was released on 2015-08-20 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of the Biology of Aging, Eighth Edition, provides readers with an update on the rapid progress in the research of aging. It is a comprehensive synthesis and review of the latest and most important advances and themes in modern biogerontology, and focuses on the trend of 'big data' approaches in the biological sciences, presenting new strategies to analyze, interpret, and understand the enormous amounts of information being generated through DNA sequencing, transcriptomic, proteomic, and the metabolomics methodologies applied to aging related problems. The book includes discussions on longevity pathways and interventions that modulate aging, innovative new tools that facilitate systems-level approaches to aging research, the mTOR pathway and its importance in age-related phenotypes, new strategies to pharmacologically modulate the mTOR pathway to delay aging, the importance of sirtuins and the hypoxic response in aging, and how various pathways interact within the context of aging as a complex genetic trait, amongst others. - Covers the key areas in biological gerontology research in one volume, with an 80% update from the previous edition - Edited by Matt Kaeberlein and George Martin, highly respected voices and researchers within the biology of aging discipline - Assists basic researchers in keeping abreast of research and clinical findings outside their subdiscipline - Presents information that will help medical, behavioral, and social gerontologists in understanding what basic scientists and clinicians are discovering - New chapters on genetics, evolutionary biology, bone aging, and epigenetic control - Provides a close examination of the diverse research being conducted today in the study of the biology of aging, detailing recent breakthroughs and potential new directions

Scientific Bulletin

Author :
Publisher :
ISBN 13 :
Total Pages : 534 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Scientific Bulletin by :

Download or read book Scientific Bulletin written by and published by . This book was released on 1987 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Transpathology

Author : Mei Tian
Publisher : Elsevier
ISBN 13 : 0323952240
Total Pages : 408 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Transpathology by : Mei Tian

Download or read book Transpathology written by Mei Tian and published by Elsevier. This book was released on 2024-06-25 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transpathology: Molecular Imaging-Based Pathology is a multidisciplinary reference on molecular imaging and pathology. The book is intended for professionals in the fields of molecular imaging, nuclear medicine, radiology, and pathology as well as students and clinical residents. The book describes the importance of non-invasive diagnosis-based precision medicine and presents a detailed description of current transpathological approaches in different aspects essential for the future development of precision medicine. It's molecular imaging approach to experimental research and clinical practice will drive the field forward and improve research outcomes. - Introduces a new concept of molecular imaging-guided precise biopsy - Links in vivo and ex vivo information at various scales by using multi-modality imaging technologies - Integrates future technologies for the non-invasive cross-validation of underlying mechanisms

Insights Into Cancer of Unknown Primary (CUP) Research: Novel Diagnostic and Therapeutic Strategies

Author : Xichun Hu
Publisher : Frontiers Media SA
ISBN 13 : 283250275X
Total Pages : 92 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Insights Into Cancer of Unknown Primary (CUP) Research: Novel Diagnostic and Therapeutic Strategies by : Xichun Hu

Download or read book Insights Into Cancer of Unknown Primary (CUP) Research: Novel Diagnostic and Therapeutic Strategies written by Xichun Hu and published by Frontiers Media SA. This book was released on 2022-10-18 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pharmacology and Applications of Chinese Materia Medica

Author : Hson-Mou Chang
Publisher : World Scientific
ISBN 13 : 9789810236922
Total Pages : 742 pages
Book Rating : 4.2/5 (369 download)

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Book Synopsis Pharmacology and Applications of Chinese Materia Medica by : Hson-Mou Chang

Download or read book Pharmacology and Applications of Chinese Materia Medica written by Hson-Mou Chang and published by World Scientific. This book was released on 1986 with total page 742 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first volume of a comprehensive 2-volume book covering modern pharmacological and clinical studies of the most commonly used Chinese herbal drugs. It contains monographs of 250 kinds of the most commonly used Chinese Materia Medica. The information on each herb was compiled by a research specialist active in the scientific investigation of that particular type of herb. The description on each drug includes an introduction (source, character and taste, actions and indications according to traditional Chinese medicine etc.), chemical composition, pharmacology, clinical studies, adverse effects and references. The translation of the book into English was done by qualified professionals in the field and the terms used are consistent with those used in Index Medicus, Chemical Abstracts and Botanical journals.

Molecular Medicines for Cancer

Author : Deepak Chitkara
Publisher : CRC Press
ISBN 13 : 1351978373
Total Pages : 610 pages
Book Rating : 4.3/5 (519 download)

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Book Synopsis Molecular Medicines for Cancer by : Deepak Chitkara

Download or read book Molecular Medicines for Cancer written by Deepak Chitkara and published by CRC Press. This book was released on 2018-09-03 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of molecular medicine covers the medical interventions targeting molecular structures and mechanisms that are involved in disease progression. In cancer, several molecular mechanisms have been shown to impact its progression, aggressiveness and chemoresistance. Increasing evidence demonstrates the role of nanotechnology and outcome of molecular therapy. Several books have discussed molecular biology and mechanisms involved in cancer, but this text gives an account of molecular therapeutics in cancer relating to advancements of nanotechnology. It provides a description of the multidisciplinary field of molecular medicines and its targeted delivery to cancer using nanotechnology. Key Features: Provides current information in the multidisciplinary field of molecular medicines and its targeted delivery to cancer using nanotechnology Presents important aspects of nanotechnology in the site-specific delivery of anticancer agents Includes up to date information on oligonucleotide and gene based therapies in cancer Describes small targeted molecules, antibodies and oligonucleotides which have shown to selectively target the molecular structures thereby influencing signal transduction Facilitates discussion between researchers involved in cancer therapy and nanoscientists

Animal Coronaviruses

Author : Leyi Wang
Publisher : Springer Nature
ISBN 13 : 1071620916
Total Pages : 320 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Animal Coronaviruses by : Leyi Wang

Download or read book Animal Coronaviruses written by Leyi Wang and published by Springer Nature. This book was released on 2022-02-09 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed new edition compiles fully updated practical methodologies and approaches for diagnosticians and researchers working toward a better understanding of animal coronaviruses. The book explores vital techniques in virus isolation, diagnostic approaches via the detection of viral nucleic acids or proteins, serology, disease-targeted animal species models, and next-generation sequencing and bioinformatics. Written for the invaluable Springer Protocols Handbooks series, chapters contain readily reproducible laboratory protocols as well as expert tips on troubleshooting and avoiding known pitfalls. Thorough and hands-on, Animal Coronaviruses, Second Edition will help readers design and carry out their increasingly important projects in clinical research, diagnostics, disease surveillance, and epidemiological study involving this family of viruses.

Molecular Genetics of Liver Neoplasia

Author : Xin Wei Wang
Publisher : Springer Science & Business Media
ISBN 13 : 1441960821
Total Pages : 390 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Molecular Genetics of Liver Neoplasia by : Xin Wei Wang

Download or read book Molecular Genetics of Liver Neoplasia written by Xin Wei Wang and published by Springer Science & Business Media. This book was released on 2010-11-08 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Primary liver cancer is the third most deadly and fifth most common cancer worldwide (~500,000 deaths annually), with a sharp increase of incidence in the United States in recent years. Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) are the major types of primary liver cancer. Risk factors include gender, hepatitis B virus (HBV), hepatitis C virus (HCV), cirrhosis, metabolism diseases, diabetes, obesity, toxins, excess alcohol consumption and smoking. Liver cancer arises most frequently in inflammatory livers with extensive oxidative stress due to viral hepatitis which causes over 80% of HCC cases worldwide. Currently, survival remains dismal for most HCC and CC patients, largely due to the tumor’s aggressiveness at the time of diagnosis and the lack of effective therapy.

The Rose and Mackay Textbook of Autoimmune Diseases

Author : M. Eric Gershwin
Publisher : Elsevier
ISBN 13 : 0443239479
Total Pages : 1842 pages
Book Rating : 4.4/5 (432 download)

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Book Synopsis The Rose and Mackay Textbook of Autoimmune Diseases by : M. Eric Gershwin

Download or read book The Rose and Mackay Textbook of Autoimmune Diseases written by M. Eric Gershwin and published by Elsevier. This book was released on 2024-08-05 with total page 1842 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Rose-Mackay Textbook of Autoimmune Diseases, Seventh Edition is a comprehensive reference that emphasizes the "3 P's" of 21st Century medicine: precision, prediction, and prevention. Topics cover the modern systems approach to biology that involves large amounts of personalized, ongoing physiologic data ("omics") coupled with advanced methods of analysis, new tests of genetic engineering, such as CRISPR, auto inflammatory diseases, autoimmune responses to tumor immunotherapy, and information on normal immune response and disorders. Each of the major autoimmune disorders is discussed by researchers and clinical investigators experienced in dealing with patients. This new edition continues its success with 75% of the content revised, updated, or completely new. This edition is a valuable resource to clinicians involved in the diagnosis and treatment of autoimmune disease, as well as to scientists who want to follow developments in the field. - Provides new research on autoimmune diseases, their diagnosis, prevention, and therapy - Covers a complete range of all common, rare and new autoimmune diseases, including cancer and COVID - Extensively revised with 75% new material based on autoimmunity, developments in the different diagnosis and therapies for these autoimmune diseases, and a completely updated description of the different diseases - Supplemented with a website that hosts a Podcast per chapter

Sirtuin Biology in Cancer and Metabolic Disease

Author : Kenneth Maiese
Publisher : Elsevier
ISBN 13 : 0128224843
Total Pages : 301 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Sirtuin Biology in Cancer and Metabolic Disease by : Kenneth Maiese

Download or read book Sirtuin Biology in Cancer and Metabolic Disease written by Kenneth Maiese and published by Elsevier. This book was released on 2021-02-20 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sirtuin Biology in Cancer and Metabolic Disease: Cellular Pathways for Clinical Discovery offers a compelling and thought-provoking perspective for the examination of the intriguing biology of sirtuins that ties cancer and metabolic disease together and provides a critical platform for the development of sirtuin-based novel therapeutic strategies to effectively treat cancer and metabolic disorders with precision in order to minimize any potentially detrimental clinical outcomes. An exciting prospect for the development of innovative therapeutics for cancer and metabolic disorders involves sirtuins. Sirtuins are histone deacetylases that have an intricate role in the onset and development of cancer and metabolic disease. Implementing a translational medicine format, this innovative reference highlights the ability of sirtuins to oversee critical pathways that involve stem cell maintenance, cellular proliferation, metabolic homeostasis, apoptosis, and autophagy that can impact cellular dysfunction and unchecked cellular growth that can occur during cancer and metabolic disease. Each chapter offers an intuitive perspective of advances on the application of sirtuin pathways for cancer and metabolic disease that will be become a "go-to" resource for a broad audience of scientists, physicians, pharmaceutical industry experts, nutritionists, and students. - Chapters are authored by internationally recognized experts who elucidate the intimate relationship between cancer and metabolic disease that intersects with sirtuin pathways - Presents the basic and clinical role of sirtuins in regard to cancer and metabolic disease - Summarizes the multidiscipline views and publications for this exciting field of sirtuins for the development of new clinical treatments for cancer and metabolic disease - Provides a vital foundation for a broad audience of healthcare providers, scientists, drug developers, and students in both clinical and research settings

Tumor Microenvironment

Author : Alexander Birbrair
Publisher : Springer Nature
ISBN 13 : 3030366677
Total Pages : 108 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Tumor Microenvironment by : Alexander Birbrair

Download or read book Tumor Microenvironment written by Alexander Birbrair and published by Springer Nature. This book was released on 2020-02-14 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the role of chemokines in the tumor microenvironment. Each chapter focuses on the chemokines patterns of expression, their regulation, and their roles in immune cell recruitment, as well as how they affect cancer immunity and tumorigenesis. Taken alongside its companion volumes, Tumor Microenvironment: The Role of Chemokines – Part A updates us on what we know about various aspects of the tumor microenvironment as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking a comprehensive update on research in the tumor microenvironment.

The Use of CRISPR/cas9, ZFNs, TALENs in Generating Site-Specific Genome Alterations

Author :
Publisher : Academic Press
ISBN 13 : 0128013346
Total Pages : 594 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis The Use of CRISPR/cas9, ZFNs, TALENs in Generating Site-Specific Genome Alterations by :

Download or read book The Use of CRISPR/cas9, ZFNs, TALENs in Generating Site-Specific Genome Alterations written by and published by Academic Press. This book was released on 2014-11-04 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers recent research and methods development for changing the DNA sequence within the genomes of cells and organisms. Focusing on enzymes that generate double-strand breaks in DNA, the chapters describe use of molecular tools to introduce or delete genetic information at specific sites in the genomes of animal, plant and bacterial cells. - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Covers research methods in biomineralization science - Contains sections on such topics as genome editing, genome engineering, CRISPR, Cas9, TALEN and zinc finger nuclease

Vaccines for Biodefense and Emerging and Neglected Diseases

Author : Alan D.T. Barrett
Publisher : Academic Press
ISBN 13 : 0080919022
Total Pages : 1519 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Vaccines for Biodefense and Emerging and Neglected Diseases by : Alan D.T. Barrett

Download or read book Vaccines for Biodefense and Emerging and Neglected Diseases written by Alan D.T. Barrett and published by Academic Press. This book was released on 2009-03-05 with total page 1519 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last 20 years has seen a rapid increase in infectious diseases, particularly those that are termed "emerging diseases" such as SARS, "neglected diseases" such as malaria and those that are deemed biothreats such as anthrax. It is well-recognized that the most effective modality for preventing infectious diseases is vaccination. This book provides researchers with a better understanding of what is currently known about these diseases, including whether there is a vaccine available or under development. It also informs readers of the key issues in development of a vaccine for each disease. - Provides a comprehensive treatise of the agents that are responsible for emerging and neglected diseases and those that can be used as biothreats - Includes the processes such as the vaccine development pathway, vaccine manufacturing and regulatory issues that are critical to the generation of these vaccines to the marketplace - Each chapter will include a map of the world showing where that particular disease is naturally found

Metal Nanoparticles for Drug Delivery and Diagnostic Applications

Author : Muhammad Raza Shah
Publisher : Elsevier
ISBN 13 : 0128169605
Total Pages : 356 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Metal Nanoparticles for Drug Delivery and Diagnostic Applications by : Muhammad Raza Shah

Download or read book Metal Nanoparticles for Drug Delivery and Diagnostic Applications written by Muhammad Raza Shah and published by Elsevier. This book was released on 2019-10-22 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal Nanoparticles for Drug Delivery and Diagnostic Applications addresses the lifecycle of metal nanoparticles, from synthesis and characterization, to applications in drug delivery and targeting. It is an important resource for those in biomaterials, nanomedicine and pharmaceutical sciences, exploring gold, silver and iron-based drug delivery systems for controlled and targeted delivery of potential drugs and genes for enhanced clinical efficacy. Nanotechnology is widely used in drug delivery due to its ability to reduce plasma fluctuation of drugs, high solubility, and efficiency, the relatively low cost of nanoscale products, and enhancement of patient comfort, hence this resource is a welcome edition to the science.

Genetically Modified Organisms in Food

Author : Ronald Ross Watson
Publisher : Academic Press
ISBN 13 : 0128025301
Total Pages : 517 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Genetically Modified Organisms in Food by : Ronald Ross Watson

Download or read book Genetically Modified Organisms in Food written by Ronald Ross Watson and published by Academic Press. This book was released on 2015-08-20 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetically Modified Organisms in Food focuses on scientific evaluation of published research relating to GMO food products to assert their safety as well as potential health risks. This book is a solid reference for researchers and professionals needing information on the safety of GMO and non-GMO food production, the economic benefits of both GMO and non-GMO foods, and includes in-depth coverage of the surrounding issues of genetic engineering in foods. This is a timely publication written by a team of scientific experts in the field who present research results to help further more evidence based research to educate scientists, academics, government professionals about the safety of the global food supply. - Provides the latest on research and development in the field of GMOs and non-GMO safety issues and possible risk factors incorporating evidence based reviews for a better understanding of these issues - Covers various aspects of GMO production, analysis and identification to better understand GMO development and use - Includes definitions, a brief overview and history of GM foods from a global perspective and concise summaries with recommendations for actions for each chapter

Advances in PGPR Research

Author : Harikesh Bahadur Singh
Publisher : CABI
ISBN 13 : 1786390329
Total Pages : 468 pages
Book Rating : 4.7/5 (863 download)

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Book Synopsis Advances in PGPR Research by : Harikesh Bahadur Singh

Download or read book Advances in PGPR Research written by Harikesh Bahadur Singh and published by CABI. This book was released on 2017-11-24 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rhizosphere biology is approaching a century of investigations wherein growth-promoting rhizomicroorganisms (PGPR) have attracted special attention for their ability to enhance productivity, profitability and sustainability at a time when food security and rural livelihood are a key priority. Bio-inputs - either directly in the form of microbes or their by-products - are gaining tremendous momentum and harnessing the potential of agriculturally important microorganisms could help in providing low-cost and environmentally safe technologies to farmers. One approach to such biologically-based strategies is the use of naturally occurring products such as PGPR. Written by an international team of experts, this book considers new concepts and global issues in biopesticide research and evaluates the implications for sustainable productivity. It is an invaluable resource for researchers in applied agricultural biotechnology, microbiology and soil science, and also for industry personnel in these areas.

Clinical Proteomics

Author : Antonia Vlahou
Publisher : Springer Science & Business Media
ISBN 13 : 158829837X
Total Pages : 401 pages
Book Rating : 4.5/5 (882 download)

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Book Synopsis Clinical Proteomics by : Antonia Vlahou

Download or read book Clinical Proteomics written by Antonia Vlahou and published by Springer Science & Business Media. This book was released on 2008-01-18 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, a select group of researchers has contributed their state-of-the-art methodologies on protein profiling and identification of disease biomarkers in tissues, microdissected cells and body fluids. The book integrates biochemistry, pathology, analytical technology, bioinformatics, and proteome informatics. Experimental approaches are thoroughly detailed and explained through a step-by-step instructional format that ensures successful results.