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Author : James Benton Gloer
Publisher :
ISBN 13 :
Total Pages : 266 pages
Book Rating : 4.:/5 (318 download)
Download or read book Structures of the Didemnins written by James Benton Gloer and published by . This book was released on 1983 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Atta-ur Rahman
Publisher : Elsevier
ISBN 13 : 0444634703
Total Pages : 547 pages
Book Rating : 4.4/5 (446 download)
Download or read book Studies in Natural Products Chemistry written by Atta-ur Rahman and published by Elsevier. This book was released on 2015-01-20 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. The series also covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. - Focuses on the chemistry of bioactive natural products - Contains contributions by leading authorities in the field - Presents sources of new pharmacophores
Author : Bill J. Baker
Publisher : CRC Press
ISBN 13 : 1466582138
Total Pages : 613 pages
Book Rating : 4.4/5 (665 download)
Download or read book Marine Biomedicine written by Bill J. Baker and published by CRC Press. This book was released on 2015-11-05 with total page 613 pages. Available in PDF, EPUB and Kindle. Book excerpt: Marine Biomedicine: From Beach to Bedside assesses current efforts in marine biomedicine and evaluates the implications of recent advances on the future of the field.Richly illustrated in full color to enhance reader comprehension, the book covers four sections. The first one addresses the technology that has recently been brought to bear on the st
Author : Timothy Block
Publisher : Springer Science & Business Media
ISBN 13 : 1461534623
Total Pages : 228 pages
Book Rating : 4.4/5 (615 download)
Download or read book Innovations in Antiviral Development and the Detection of Virus Infections written by Timothy Block and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE ERA OF ANTIVIRALS Introduction Although there are more than one hundred medically useful antibiotics and fungicides, there are only seven compounds licensed for use as antiviral agents, in the USA. Some of these (acyclovir and ganciclovir) are actually derivatives of each other, making the number of new discoveries even smaller. Moreover, most of these agents are of only limited therapeutic value and have substantial toxicity. It has been more than 100 years ago since Pasteur studied rabies virus (2) and Rous (4) showed that a small filterable agent (not bacteria) caused disease (sarcoma) in chickens. It was nearly 100 years ago that yellow fever virus, the first recognized human pathogenic virus, was unambiguously associated with disease (3). Enteroviruses were cultured for the first time nearly 50 years ago (1). Why then has effective chemotherapy against viruses lagged behind that of other microorganisms? Viruses are often difficult to grow and image. However, with the dynamic advances in molecular biology and increased sophistication in tissue culture, the field of virology has blossomed and resulted in improved methods for detection of virus infection. The use of viruses as models of gene regulation and replication has also resulted in a massive accumulation of information.
Author : Roy E. Martin
Publisher : CRC Press
ISBN 13 : 9781566768894
Total Pages : 986 pages
Book Rating : 4.7/5 (688 download)
Download or read book Marine and Freshwater Products Handbook written by Roy E. Martin and published by CRC Press. This book was released on 2000-04-04 with total page 986 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive handbook of seafood information! This definitive reference is the most comprehensive handbook of information ever assembled on foods and other products from fresh and marine waters. Marine and Freshwater Products Handbook covers the acquisition, handling, biology, and the science and technology of the preservation and processing of fishery and marine products. The array of topics covered includes: aquaculture fisheries management, and harvesting o fish meal and fish oil o fish protein concentrates o seaweed products o products from shell o other industrial products o bioactive compounds o cookery o specialty products o surimi and mince o HACCP o modern processing methods o religious and cultural aspects of water products o marine toxins and seafood intolerances o contamination in shellfish growing areas o pathogens in fish and shellfish. Marketing, transportation and distribution, retailing, import and export, and a look to the future of the seafood industry are also addressed. Extensive coverage of species All major marine and freshwater finfish species are covered, as well as processing technologies: fresh fish, preserved fish, finfish processing, and other processed products. Crustaceans and other useful marine and freshwater species and their processing are also covered. These include: mollusk o clams o oysters o scallops o abalone o squid o shrimp o lobster o crawfish o crabs o eels o turtles o sea urchin o octopus o snails o alligator. The definitive seafood industry sourcebook Marine and Freshwater Products Handbook incorporates the advances in biotechnology and molecular biology, including potential drugs and medicinal products; the manufacture of chemicals from the sea; seafood safety, including toxin detection techniques and HACCP, and processing technologies. With contributions from more than 50 experts, helpful, data-filled tables and charts, numerous references and photos, this is the sourcebook for everyone involved in products from our waters. It will serve as the standard reference for the seafood industry for years to come.
Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642745601
Total Pages : 180 pages
Book Rating : 4.6/5 (427 download)
Download or read book Bioorganic Marine Chemistry written by and published by Springer Science & Business Media. This book was released on 2013-03-07 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first three chapters of Vol. 3 of Bio-organic Marine Chemistry deal with the chemistry and function of peptides. Chapter 1 by Ireland and coworkers serves as an introduction to marine-derived peptides. It is arranged phyletically and encompasses the entire range from dipeptides to a compound with 95 amino acid residues. Peptides involved in primary metabolism and hence belonging to the realm of macromolecular biochemistry are excluded. However, it might be mentioned in passing that the dividing line between large and small molecule chemistry is continually becoming less distinct. Not only are more compounds of intermediate size, from 1,000 to 10,000 dalton, being discovered, but instruments and techniques, particularly in mass spectrometry and nuclear magnetic resonance have been developed for their structural elucidation by what is considered small molecule methodology. Two groups of peptides are discussed in separate chapters. Biologists who have observed and described the mating behavior of diverse species of marine invertebrates have long surmised that a chemical mechanism might be operating in many cases of individual as well as mass fertilization. The chemical activators of sea urchin sperm prove to be a series of peptides, whose structures and activity are discussed by Suzuki.
Author : G.H. Wagman
Publisher : Elsevier
ISBN 13 : 0080858481
Total Pages : 635 pages
Book Rating : 4.0/5 (88 download)
Download or read book Natural Products Isolation written by G.H. Wagman and published by Elsevier. This book was released on 1988-12-01 with total page 635 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new book encompasses, in great detail, the most recent progress made in the isolation and separation of natural products. It covers antibiotics, marine and plant-derived substances, enzyme inhibitors and interferons. The most recent separation methodology is described. Although there is a bias toward antibiotics, it was done because this is still the largest natural products area of research.The fourteen chapters are written by experts in their respective fields. The first two chapters are largely devoted to new methodology applied to purification of a variety of compounds. They include an extensive review and new applications of counter-current chromatography and the newly emerging HPLC-photodiode array technology. Chapter 3 provides a review of affinity chromatography applied to the separation of antibiotics for the first time. Next are chapters on antimicrobials with an update on all the most recent &bgr;-lactam (after 1976) discoveries. A comprehensive review of a very important class of antiparasitic agents - the avermectins - follows. An update of isolation and purification of a variety of marine-derived compounds is next. The succeeding chapter is a comprehensive review of the most recent developments in isolation and purification of interferons. This is followed by a discussion of enzyme inhibitors and their isolation and purification and ties in with a chapter on plant-derived natural products, some of which are also in this same category. The final chapter is a futuristic essay indicating the isolation of minute amounts of natural products and the fascinating biological properties which they possess.The book has extensive isolation schemes, tables, figures and chemical structures. In many instances a short summary of the producing organism, brief chemical description and structure and biological activity of the compounds is presented. Detailed information of extraction, separation and purification techniques follow. Each chapter has an extensive bibliography and, where applicable, an appendix showing sources of materials and equipment. A detailed index to the subject matter is included at the end of the book.The book thus offers the reader: up-to-date reviews (including 1988) of specific topics in the natural products field not to be found elsewhere; information on new chromatographic methods and techniques described in sufficient detail to be utilized by investigators in this area of research; and extensive references to enable the serious researcher to pursue particular information. It will appeal to pharmaceutical and natural products researchers and is a valuable acquisition for university chemistry and biochemistry departments.
Author : Lesley-Ann Giddings
Publisher : Springer
ISBN 13 : 3319143611
Total Pages : 156 pages
Book Rating : 4.3/5 (191 download)
Download or read book Bioactive Compounds from Marine Extremophiles written by Lesley-Ann Giddings and published by Springer. This book was released on 2015-01-06 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This SpringerBrief sheds new light on bioactive materials from marine extremophiles. It deals with all aspects of the chemical compounds produced by organisms living under extreme conditions that may have potential as drugs or lead to novel drugs for human use.
Author : Prabhakar, Pranav Kumar
Publisher : IGI Global
ISBN 13 :
Total Pages : 768 pages
Book Rating : 4.3/5 (693 download)
Download or read book Marine Metabolites in Disease Management written by Prabhakar, Pranav Kumar and published by IGI Global. This book was released on 2024-09-25 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the exploration of marine ecosystems has unveiled a plethora of bioactive compounds with remarkable therapeutic potential. The oceans, covering over 70% of the Earth’s surface, are a rich source of biodiversity, harbouring organisms that have evolved unique biochemical pathways to survive in extreme conditions. These marine metabolites, produced by marine microorganisms, invertebrates, and algae, have demonstrated significant pharmacological activities, ranging from antimicrobial and anti-inflammatory to anticancer and neuroprotective properties. Marine Metabolites in Disease Management compiles and synthesizes current research on the role of marine-derived compounds in the prevention and treatment of various diseases. This work is a collaborative effort, bringing together insights from leading researchers and clinicians who have dedicated their careers to the study of marine natural products. Through their contributions, the gap between marine biotechnology and clinical applications is bridged, providing a comprehensive resource for researchers, healthcare professionals, and policymakers.
Author : Vincent P. Gullo
Publisher : Newnes
ISBN 13 : 1483292134
Total Pages : 480 pages
Book Rating : 4.4/5 (832 download)
Download or read book Discovery of Novel Natural Products with Therapeutic Potential written by Vincent P. Gullo and published by Newnes. This book was released on 2013-10-22 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although science has discovered effective drugs for many of the diseases that afflict mankind, many human health problems remain untreatable. The search for novel therapeutic agents is always ongoing. This book will describe some of the diverse sourcesof natural products, such as terrestrial and marine environments; and will review how research has increased knowledge of biological systems and human disease, leading to the design of targeted asssays, amenable to high volume screening.
Author :
Publisher :
ISBN 13 :
Total Pages : 936 pages
Book Rating : 4.E/5 ( download)
Download or read book Biochemistry Abstracts written by and published by . This book was released on 1981-07 with total page 936 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : J. H. Jones
Publisher : Royal Society of Chemistry
ISBN 13 : 0851862144
Total Pages : 341 pages
Book Rating : 4.8/5 (518 download)
Download or read book Amino Acids and Peptides written by J. H. Jones and published by Royal Society of Chemistry. This book was released on 1992 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.
Author : David H. Attaway
Publisher : Springer Science & Business Media
ISBN 13 : 9780306441745
Total Pages : 532 pages
Book Rating : 4.4/5 (417 download)
Download or read book Pharmaceutical and Bioactive Natural Products written by David H. Attaway and published by Springer Science & Business Media. This book was released on 1993-03-31 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biotechnology may be defined as the application of scientific and engineering principles to the processing of materials by biological agents to provide goods and services (Bullet al. , 1982, p. 21) or as any technique that uses living organisms (or parts of organisms) to make or modify products, to improve plants or animals, or to develop microorganisms for specific use (OTC, 1988). In line with these broad definitions we can consider marine biotechnology as the use of marine organisms or their constituents for useful purposes in a controlled fashion. This series will explore a range of scientific advances in support of marine biotechnology. It will provide information on advances in three categories: (1) basic knowledge, (2) ap plied research and development, and (3) commercial and institutional issues. We hope the presentation of the topics will generate interest and interaction among readers in the academic world, government, and industry. This first volume examines chemical and biological properties of some natural products that are useful or potentially useful in research and in the chemical and pharmaceutical industries. One chapter describes a system for producing such substances on a large scale. Biotechnology incorporates molecular biology in order to go beyond tradi tional biochemical technology such as the production of antibiotic drugs from bacterial cultures in bioreactors. Development of the technology for production of antibiotics in this way resulted from fundamental advances in chemistry, phar macology, microbiology, and biochemical engineering.
Author : Lixin Zhang
Publisher : Springer Science & Business Media
ISBN 13 : 1592599761
Total Pages : 380 pages
Book Rating : 4.5/5 (925 download)
Download or read book Natural Products written by Lixin Zhang and published by Springer Science & Business Media. This book was released on 2007-11-17 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fresh examination of the past successes of natural products as medicines and their new future from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discoveries, to microbial diversity, to specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious.
Author : Michael B. Smith
Publisher : CRC Press
ISBN 13 : 1000601331
Total Pages : 916 pages
Book Rating : 4.0/5 (6 download)
Download or read book Organic Chemistry written by Michael B. Smith and published by CRC Press. This book was released on 2022-09-23 with total page 916 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the premise that many, if not most, reactions in organic chemistry can be explained by variations of fundamental acid–base concepts, Organic Chemistry: An Acid–Base Approach provides a framework for understanding the subject that goes beyond mere memorization. Using several techniques to develop a relational understanding, it helps students fully grasp the essential concepts at the root of organic chemistry. This new edition was rewritten largely with the feedback of students in mind and is also based on the author’s classroom experiences using the previous editions. Highlights of the Third Edition Include: Extensively revised chapters that improve the presentation of material. Features the contributions of more than 65 scientists, highlighting the diversity in organic chemistry. Features the current work of over 30 organic chemists, highlighting the diversity in organic chemistry. Many new reactions are featured that are important in modern organic chemistry. Video lectures are provided in a .mov format, accessible online as a ‘built-in’ ancillary for the book. The homework is available online, gratis to all users. The third edition of Organic Chemistry: An Acid–Base Approach constitutes a significant improvement upon a unique introductory technique to organic chemistry. The reactions and mechanisms it covers are the most fundamental concepts in organic chemistry that are applied to industry, biological chemistry, biochemistry, molecular biology, and pharmacy. Using an illustrated conceptual approach rather than presenting sets of principles and theories to memorize, it gives students a more concrete understanding of the material.
Author : Alan L. Harvey
Publisher : CRC Press
ISBN 13 : 9780471975090
Total Pages : 232 pages
Book Rating : 4.9/5 (75 download)
Download or read book Advances in Drug Discovery Techniques written by Alan L. Harvey and published by CRC Press. This book was released on 1998-08-15 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to techniques for the discovery and evaluation of pharamcologically active compounds for therapeutic development, this book covers rational drug design, high-throughput screening, and genetic approaches to drug discovery. The authors focus on advances in the use of combinatorial chemistry and natural products, both of which support the chemical diversity for many drug screening programmes. They examine typical screening studies and their link to robotics and informatics in detail and present an overview of current progress within anitsense therapeutics. The book explores the rapid changes in drug discovery resulting from developments in molecular biology, robotics, and informatics.
Author : Georg F. Weber
Publisher : Springer
ISBN 13 : 3319132784
Total Pages : 486 pages
Book Rating : 4.3/5 (191 download)
Download or read book Molecular Therapies of Cancer written by Georg F. Weber and published by Springer. This book was released on 2015-07-22 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Therapies of Cancer comprehensively covers the molecular mechanisms of anti-cancer drug actions in a comparably systematic fashion. While there is currently available a great deal of literature on anti-cancer drugs, books on the subject are often concoctions of invited review articles superficially connected to one another. There is a lack of comprehensive and systematic text on the topic of molecular therapies in cancer. A further deficit in the relevant literature is a progressive sub-specialization that typically limits textbooks on cancer drugs to cover either pharmacology or medicinal chemistry or signal transduction, rather than explaining molecular drug actions across all those areas; Molecular Therapies of Cancer fills this void. The book is divided into five sections: 1. Molecular Targeting of Cancer Cells; 2. Emerging and Alternative Treatment Modalities; 3. Molecular Targeting of Tumor-Host Interactions; 4. Anti-Cancer Drug Pharmacokinetics; and 5. Supportive Therapies.
