Stochastic Modeling of Multi-locus Recombination in Mendelian Populations

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (775 download)

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Book Synopsis Stochastic Modeling of Multi-locus Recombination in Mendelian Populations by : Amir R. Raji-Kermany

Download or read book Stochastic Modeling of Multi-locus Recombination in Mendelian Populations written by Amir R. Raji-Kermany and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Recombination Variability and Evolution

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Publisher : Springer Science & Business Media
ISBN 13 : 9780412494109
Total Pages : 384 pages
Book Rating : 4.4/5 (941 download)

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Book Synopsis Recombination Variability and Evolution by : A.B. Korol

Download or read book Recombination Variability and Evolution written by A.B. Korol and published by Springer Science & Business Media. This book was released on 1994-08-31 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using an interdisciplinary approach, the authors provide an adaptionist interpretation of the basic features of recombination, its evolutionary significance as a key process in reproduction and its importance in genetic mapping. The book synthesizes much recent information in the fields of evloutionary genetics of recombination, the analysis of genetic markers and breeding applications. The authors analyse recombination through a consideration of computer models, large Drosophila populations and an empirical approach to current theories. Practically-orientated readers will be interested in the discussion of a wide spectrum of mapping methods and the new algorithms proposed for genetic mapping of quantitative loci.

The Foundations of Population Genetics

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Publisher : MIT Press
ISBN 13 : 0262047578
Total Pages : 255 pages
Book Rating : 4.2/5 (62 download)

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Book Synopsis The Foundations of Population Genetics by : Daniel M. Weinreich

Download or read book The Foundations of Population Genetics written by Daniel M. Weinreich and published by MIT Press. This book was released on 2023-08-29 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: An accessible but rigorous treatment of the theoretical foundations of population genetics. Population genetics—the branch of evolutionary biology concerned with understanding how and why populations’ genetic compositions change over time—rests on a well-developed theoretical foundation that draws on genetics, mathematics, and computer science. This textbook provides an approachable but rigorous treatment for advanced undergraduate and graduate students interested in building a quantitative understanding of the genetics of evolution. Existing texts either assume very mathematically advanced readers, or avoid much of the underlying theory, instead focusing on current methods of data analysis. In contrast, The Foundations of Population Genetics develops the theory from first principles. Requiring only confidence in algebra, this self-contained, student-friendly book illustrates the conceptual framework, terminology, and methods of mathematical modeling. It progressively introduces concepts from genetics as needed, while emphasizing biological implications throughout. As a result, readers come away with a deep understanding of the structure of population genetics without needing to master its mathematics. Connects theory with the most recent genetic data better than existing texts Features engaging real-world examples and extensive original figures Provides dozens of carefully scaffolded questions that deepen the reader's understanding of key concepts Ideal as a succinct reference for established scientists in biology, medicine, and computer science Instructor resources available

Research Awards Index

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Publisher :
ISBN 13 :
Total Pages : 834 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Research Awards Index by :

Download or read book Research Awards Index written by and published by . This book was released on 1987 with total page 834 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Game Equilibrium Models I

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Publisher : Springer Science & Business Media
ISBN 13 : 3662026740
Total Pages : 338 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Game Equilibrium Models I by : Reinhard Selten

Download or read book Game Equilibrium Models I written by Reinhard Selten and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are two main approaches towards the phenotypic analysis of frequency dependent natural selection. First, there is the approach of evolutionary game theory, which was introduced in 1973 by John Maynard Smith and George R. Price. In this theory, the dynamical process of natural selection is not modeled explicitly. Instead, the selective forces acting within a population are represented by a fitness function, which is then analysed according to the concept of an evolutionarily stable strategy or ESS. Later on, the static approach of evolutionary game theory has been complemented by a dynamic stability analysis of the replicator equations. Introduced by Peter D. Taylor and Leo B. Jonker in 1978, these equations specify a class of dynamical systems, which provide a simple dynamic description of a selection process. Usually, the investigation of the replicator dynamics centers around a stability analysis of their stationary solutions. Although evolutionary stability and dynamic stability both intend to characterize the long-term outcome of frequency dependent selection, these concepts differ considerably in the 'philosophies' on which they are based. It is therefore not too surprising that they often lead to quite different evolutionary predictions (see, e. g. , Weissing 1983). The present paper intends to illustrate the incongruities between the two approaches towards a phenotypic theory of natural selection. A detailed game theoretical and dynamical analysis is given for a generic class of evolutionary normal form games.

Stochastic Models in Population Genetics

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Publisher : Hutchinson Ross Publishing Company
ISBN 13 :
Total Pages : 504 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Stochastic Models in Population Genetics by : Wen-Hsiung Li

Download or read book Stochastic Models in Population Genetics written by Wen-Hsiung Li and published by Hutchinson Ross Publishing Company. This book was released on 1977 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pioneering works; Clasical single-locus problems; Molecular population genetics; Multilocus problems; Structured populations; Methematical problems.

Population Genetics of Multiple Loci

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Publisher :
ISBN 13 :
Total Pages : 392 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Population Genetics of Multiple Loci by : Freddy B. Christiansen

Download or read book Population Genetics of Multiple Loci written by Freddy B. Christiansen and published by . This book was released on 2000-01-10 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Population Genetics of Multiple Loci F. B. Christiansen University of Aarhus, Denmark "This is a very beautiful and powerful study of an area that Christiansen has dominated for many years." - Marcus Feldman, Stanford University, USA Population genetics thrives on the constant interaction between theoretical and empirical knowledge. In the first instance, population genetics was developed using one-locus, two-allele models for genetic variation. The simplicity of these models opened up theoretical developments in population and evolutionary genetics to biologists without specialist training in mathematics. Population genetics of multi-allelic loci is more complex and requires more mathematical insight, and its study is predominantly undertaken by mathematical biologists. Traditional formulations of multi-locus theory do not simplify by assuming two alleles per locus. In this elegant presentation the author provides a formulation of multi-locus population genetics that retains the simplicity of two-allele models. * Provides an accessible and natural extension of classical population genetics to multiple loci * Exposes the population genetic aspects of sexual reproduction * Describes the complexity of evolutionary interactions among genes * Provides the background for insight into the functioning of genetic algorithms applied in computer science * Written by a world leader in the field The book is divided into two main sections. Part I - Recombination and Segregation - includes coverage of random mating, inbreeding, migration and mixing. Part II - Selection - covers numerous phenomena involving natural selection including viability, fertility, mutation and migration. The author has successfully presented the theory in a way that is intelligible to anyone with a reasonably good background in basic mathematics and is devoted to learning multiple loci population genetics. The text is primarily aimed at advanced undergraduate and postgraduate students and researchers interested in genetics and population biology. It is also essential reading for those working or researching in biomathematics and adaptive computing.

The Philosophy of Science

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Publisher : Psychology Press
ISBN 13 : 0415939275
Total Pages : 1012 pages
Book Rating : 4.4/5 (159 download)

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Book Synopsis The Philosophy of Science by : Sahotra Sarkar

Download or read book The Philosophy of Science written by Sahotra Sarkar and published by Psychology Press. This book was released on 2006 with total page 1012 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first in-depth reference to the field that combines scientific knowledge with philosophical inquiry, this encyclopedia brings together a team of leading scholars to provide nearly 150 entries on the essential concepts in the philosophy of science. The areas covered include biology, chemistry, epistemology and metaphysics, physics, psychology and mind, the social sciences, and key figures in the combined studies of science and philosophy. (Midwest).

Handbook of Statistical Genomics

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Publisher : John Wiley & Sons
ISBN 13 : 1119429250
Total Pages : 1828 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Handbook of Statistical Genomics by : David J. Balding

Download or read book Handbook of Statistical Genomics written by David J. Balding and published by John Wiley & Sons. This book was released on 2019-07-09 with total page 1828 pages. Available in PDF, EPUB and Kindle. Book excerpt: A timely update of a highly popular handbook on statistical genomics This new, two-volume edition of a classic text provides a thorough introduction to statistical genomics, a vital resource for advanced graduate students, early-career researchers and new entrants to the field. It introduces new and updated information on developments that have occurred since the 3rd edition. Widely regarded as the reference work in the field, it features new chapters focusing on statistical aspects of data generated by new sequencing technologies, including sequence-based functional assays. It expands on previous coverage of the many processes between genotype and phenotype, including gene expression and epigenetics, as well as metabolomics. It also examines population genetics and evolutionary models and inference, with new chapters on the multi-species coalescent, admixture and ancient DNA, as well as genetic association studies including causal analyses and variant interpretation. The Handbook of Statistical Genomics focuses on explaining the main ideas, analysis methods and algorithms, citing key recent and historic literature for further details and references. It also includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between chapters, tying the different areas together. With heavy use of up-to-date examples and references to web-based resources, this continues to be a must-have reference in a vital area of research. Provides much-needed, timely coverage of new developments in this expanding area of study Numerous, brand new chapters, for example covering bacterial genomics, microbiome and metagenomics Detailed coverage of application areas, with chapters on plant breeding, conservation and forensic genetics Extensive coverage of human genetic epidemiology, including ethical aspects Edited by one of the leading experts in the field along with rising stars as his co-editors Chapter authors are world-renowned experts in the field, and newly emerging leaders. The Handbook of Statistical Genomics is an excellent introductory text for advanced graduate students and early-career researchers involved in statistical genetics.

Journal of Mathematical Biology

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Publisher :
ISBN 13 :
Total Pages : 840 pages
Book Rating : 4.:/5 (49 download)

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Book Synopsis Journal of Mathematical Biology by :

Download or read book Journal of Mathematical Biology written by and published by . This book was released on 1990 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mathematical Evolutionary Theory

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Publisher :
ISBN 13 : 9780691609171
Total Pages : 0 pages
Book Rating : 4.6/5 (91 download)

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Book Synopsis Mathematical Evolutionary Theory by : Marcus W. Feldman

Download or read book Mathematical Evolutionary Theory written by Marcus W. Feldman and published by . This book was released on 2014-07-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The papers in this volume celebrate Samuel Karlin's contributions to mathematical evolutionary theory."--Page vii.

The Philosophy of Science: N-Z, Index

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Publisher : Taylor & Francis
ISBN 13 : 9780415977104
Total Pages : 530 pages
Book Rating : 4.9/5 (771 download)

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Book Synopsis The Philosophy of Science: N-Z, Index by : Sahotra Sarkar

Download or read book The Philosophy of Science: N-Z, Index written by Sahotra Sarkar and published by Taylor & Francis. This book was released on 2006 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first in-depth reference to the field that combines scientific knowledge with philosophical inquiry, this encyclopedia brings together a team of leading scholars to provide nearly 150 entries on the essential concepts in the philosophy of science. The areas covered include biology, chemistry, epistemology and metaphysics, physics, psychology and mind, the social sciences, and key figures in the combined studies of science and philosophy. (Midwest).

Handbook of Statistical Genomics

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119429226
Total Pages : 1224 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Handbook of Statistical Genomics by : David J. Balding

Download or read book Handbook of Statistical Genomics written by David J. Balding and published by John Wiley & Sons. This book was released on 2019-07-02 with total page 1224 pages. Available in PDF, EPUB and Kindle. Book excerpt: A timely update of a highly popular handbook on statistical genomics This new, two-volume edition of a classic text provides a thorough introduction to statistical genomics, a vital resource for advanced graduate students, early-career researchers and new entrants to the field. It introduces new and updated information on developments that have occurred since the 3rd edition. Widely regarded as the reference work in the field, it features new chapters focusing on statistical aspects of data generated by new sequencing technologies, including sequence-based functional assays. It expands on previous coverage of the many processes between genotype and phenotype, including gene expression and epigenetics, as well as metabolomics. It also examines population genetics and evolutionary models and inference, with new chapters on the multi-species coalescent, admixture and ancient DNA, as well as genetic association studies including causal analyses and variant interpretation. The Handbook of Statistical Genomics focuses on explaining the main ideas, analysis methods and algorithms, citing key recent and historic literature for further details and references. It also includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between chapters, tying the different areas together. With heavy use of up-to-date examples and references to web-based resources, this continues to be a must-have reference in a vital area of research. Provides much-needed, timely coverage of new developments in this expanding area of study Numerous, brand new chapters, for example covering bacterial genomics, microbiome and metagenomics Detailed coverage of application areas, with chapters on plant breeding, conservation and forensic genetics Extensive coverage of human genetic epidemiology, including ethical aspects Edited by one of the leading experts in the field along with rising stars as his co-editors Chapter authors are world-renowned experts in the field, and newly emerging leaders. The Handbook of Statistical Genomics is an excellent introductory text for advanced graduate students and early-career researchers involved in statistical genetics.

Human Population Genetics and Genomics

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Publisher : Academic Press
ISBN 13 : 0123860261
Total Pages : 498 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Human Population Genetics and Genomics by : Alan R. Templeton

Download or read book Human Population Genetics and Genomics written by Alan R. Templeton and published by Academic Press. This book was released on 2018-11-08 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Population Genetics and Genomics provides researchers/students with knowledge on population genetics and relevant statistical approaches to help them become more effective users of modern genetic, genomic and statistical tools. In-depth chapters offer thorough discussions of systems of mating, genetic drift, gene flow and subdivided populations, human population history, genotype and phenotype, detecting selection, units and targets of natural selection, adaptation to temporally and spatially variable environments, selection in age-structured populations, and genomics and society. As human genetics and genomics research often employs tools and approaches derived from population genetics, this book helps users understand the basic principles of these tools. In addition, studies often employ statistical approaches and analysis, so an understanding of basic statistical theory is also needed. Comprehensively explains the use of population genetics and genomics in medical applications and research Discusses the relevance of population genetics and genomics to major social issues, including race and the dangers of modern eugenics proposals Provides an overview of how population genetics and genomics helps us understand where we came from as a species and how we evolved into who we are now

Genetic Mapping and DNA Sequencing

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Publisher : Springer Science & Business Media
ISBN 13 : 1461207517
Total Pages : 229 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Genetic Mapping and DNA Sequencing by : Terry Speed

Download or read book Genetic Mapping and DNA Sequencing written by Terry Speed and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetics mapping, physical mapping and DNA sequencing are the three key components of the human and other genome projects. Statistics, mathematics and computing play important roles in all three, as well as in the uses to which the mapping and sequencing data are put. This volume edited by key researchers Mike Waterman and Terry Speed reviews recent progress in the area, with an emphasis on the theory and application of genetic mapping.

Game Equilibrium Models

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Publisher :
ISBN 13 :
Total Pages : 350 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Game Equilibrium Models by :

Download or read book Game Equilibrium Models written by and published by . This book was released on 1991 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Systems Genetics

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Publisher : Cambridge University Press
ISBN 13 : 131638098X
Total Pages : 287 pages
Book Rating : 4.3/5 (163 download)

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Book Synopsis Systems Genetics by : Florian Markowetz

Download or read book Systems Genetics written by Florian Markowetz and published by Cambridge University Press. This book was released on 2015-07-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Whereas genetic studies have traditionally focused on explaining heritance of single traits and their phenotypes, recent technological advances have made it possible to comprehensively dissect the genetic architecture of complex traits and quantify how genes interact to shape phenotypes. This exciting new area has been termed systems genetics and is born out of a synthesis of multiple fields, integrating a range of approaches and exploiting our increased ability to obtain quantitative and detailed measurements on a broad spectrum of phenotypes. Gathering the contributions of leading scientists, both computational and experimental, this book shows how experimental perturbations can help us to understand the link between genotype and phenotype. A snapshot of current research activity and state-of-the-art approaches to systems genetics are provided, including work from model organisms such as Saccharomyces cerevisiae and Drosophila melanogaster, as well as from human studies.