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Stochastic Modeling In Physical And Biological Sciences
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Book Synopsis Stochastic Modeling in Physical and Biological Sciences by : V. Thangaraj
Download or read book Stochastic Modeling in Physical and Biological Sciences written by V. Thangaraj and published by . This book was released on 2016-06-28 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses basic definitions, important properties and results on Markov Chains giving examples to understand the intricacies of the theory of Markov Chains. This book elaborates continuous time stochastic processes for modeling purpose explaining in detail with examples and includes an application oriented chapter on how stochastic modeling throws light on physical sciences. Basics on branching processes and their applications are explained pedagogically with a view to develop modeling capacity in biological sciences. Queues are a ubiquitous part of everyday life. This volume throws light on the foundation for stochastic modeling on queues. Interestingly, it presents bulk service queues an offshoot of professor Medhi's foundation on queues. A monumental and seminal contribution of Professor Neuts on matrix geometric methods is presented in a neat form. Finally, it meticulously designs some stochastic biological models and shows how stochastic modeling can project the prosperity of biological sciences.
Book Synopsis Stochastic Models in Biology by : Narendra S. Goel
Download or read book Stochastic Models in Biology written by Narendra S. Goel and published by Elsevier. This book was released on 2013-10-22 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stochastic Models in Biology describes the usefulness of the theory of stochastic process in studying biological phenomena. The book describes analysis of biological systems and experiments though probabilistic models rather than deterministic methods. The text reviews the mathematical analyses for modeling different biological systems such as the random processes continuous in time and discrete in state space. The book also discusses population growth and extinction through Malthus' law and the work of MacArthur and Wilson. The text then explains the dynamics of a population of interacting species. The book also addresses population genetics under systematic evolutionary pressures known as deterministic equations and genetic changes in a finite population known as stochastic equations. The text then turns to stochastic modeling of biological systems at the molecular level, particularly the kinetics of biochemical reactions. The book also presents various useful equations such as the differential equation for generating functions for birth and death processes. The text can prove valuable for biochemists, cellular biologists, and researchers in the medical and chemical field who are tasked to perform data analysis.
Book Synopsis Stochastic Modelling for Systems Biology by : Darren J. Wilkinson
Download or read book Stochastic Modelling for Systems Biology written by Darren J. Wilkinson and published by CRC Press. This book was released on 2006-04-18 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although stochastic kinetic models are increasingly accepted as the best way to represent and simulate genetic and biochemical networks, most researchers in the field have limited knowledge of stochastic process theory. The stochastic processes formalism provides a beautiful, elegant, and coherent foundation for chemical kinetics and there is a wealth of associated theory every bit as powerful and elegant as that for conventional continuous deterministic models. The time is right for an introductory text written from this perspective. Stochastic Modelling for Systems Biology presents an accessible introduction to stochastic modelling using examples that are familiar to systems biology researchers. Focusing on computer simulation, the author examines the use of stochastic processes for modelling biological systems. He provides a comprehensive understanding of stochastic kinetic modelling of biological networks in the systems biology context. The text covers the latest simulation techniques and research material, such as parameter inference, and includes many examples and figures as well as software code in R for various applications. While emphasizing the necessary probabilistic and stochastic methods, the author takes a practical approach, rooting his theoretical development in discussions of the intended application. Written with self-study in mind, the book includes technical chapters that deal with the difficult problems of inference for stochastic kinetic models from experimental data. Providing enough background information to make the subject accessible to the non-specialist, the book integrates a fairly diverse literature into a single convenient and notationally consistent source.
Book Synopsis Stochastic Chemical Reaction Systems in Biology by : Hong Qian
Download or read book Stochastic Chemical Reaction Systems in Biology written by Hong Qian and published by Springer Nature. This book was released on 2021-10-18 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an introduction to the analysis of stochastic dynamic models in biology and medicine. The main aim is to offer a coherent set of probabilistic techniques and mathematical tools which can be used for the simulation and analysis of various biological phenomena. These tools are illustrated on a number of examples. For each example, the biological background is described, and mathematical models are developed following a unified set of principles. These models are then analyzed and, finally, the biological implications of the mathematical results are interpreted. The biological topics covered include gene expression, biochemistry, cellular regulation, and cancer biology. The book will be accessible to graduate students who have a strong background in differential equations, the theory of nonlinear dynamical systems, Markovian stochastic processes, and both discrete and continuous state spaces, and who are familiar with the basic concepts of probability theory.
Book Synopsis Stochastic Modelling for Systems Biology, Third Edition by : Darren J. Wilkinson
Download or read book Stochastic Modelling for Systems Biology, Third Edition written by Darren J. Wilkinson and published by CRC Press. This book was released on 2018-12-07 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first edition of Stochastic Modelling for Systems Biology, there have been many interesting developments in the use of "likelihood-free" methods of Bayesian inference for complex stochastic models. Having been thoroughly updated to reflect this, this third edition covers everything necessary for a good appreciation of stochastic kinetic modelling of biological networks in the systems biology context. New methods and applications are included in the book, and the use of R for practical illustration of the algorithms has been greatly extended. There is a brand new chapter on spatially extended systems, and the statistical inference chapter has also been extended with new methods, including approximate Bayesian computation (ABC). Stochastic Modelling for Systems Biology, Third Edition is now supplemented by an additional software library, written in Scala, described in a new appendix to the book. New in the Third Edition New chapter on spatially extended systems, covering the spatial Gillespie algorithm for reaction diffusion master equation models in 1- and 2-d, along with fast approximations based on the spatial chemical Langevin equation Significantly expanded chapter on inference for stochastic kinetic models from data, covering ABC, including ABC-SMC Updated R package, including code relating to all of the new material New R package for parsing SBML models into simulatable stochastic Petri net models New open-source software library, written in Scala, replicating most of the functionality of the R packages in a fast, compiled, strongly typed, functional language Keeping with the spirit of earlier editions, all of the new theory is presented in a very informal and intuitive manner, keeping the text as accessible as possible to the widest possible readership. An effective introduction to the area of stochastic modelling in computational systems biology, this new edition adds additional detail and computational methods that will provide a stronger foundation for the development of more advanced courses in stochastic biological modelling.
Book Synopsis Stochastic Processes and Applications in Biology and Medicine by : Marius Iosifescu
Download or read book Stochastic Processes and Applications in Biology and Medicine written by Marius Iosifescu and published by . This book was released on 1973 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vol. 2.
Book Synopsis Stochastic Models In The Life Sciences And Their Methods Of Analysis by : Wan Frederic Y M
Download or read book Stochastic Models In The Life Sciences And Their Methods Of Analysis written by Wan Frederic Y M and published by World Scientific. This book was released on 2019-08-29 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological processes are evolutionary in nature and often evolve in a noisy environment or in the presence of uncertainty. Such evolving phenomena are necessarily modeled mathematically by stochastic differential/difference equations (SDE), which have been recognized as essential for a true understanding of many biological phenomena. Yet, there is a dearth of teaching material in this area for interested students and researchers, notwithstanding the addition of some recent texts on stochastic modelling in the life sciences. The reason may well be the demanding mathematical pre-requisites needed to 'solve' SDE.A principal goal of this volume is to provide a working knowledge of SDE based on the premise that familiarity with the basic elements of a stochastic calculus for random processes is unavoidable. Through some SDE models of familiar biological phenomena, we show how stochastic methods developed for other areas of science and engineering are also useful in the life sciences. In the process, the volume introduces to biologists a collection of analytical and computational methods for research and applications in this emerging area of life science. The additions broaden the available tools for SDE models for biologists that have been limited by and large to stochastic simulations.
Book Synopsis Stochastic Modeling by : Nicolas Lanchier
Download or read book Stochastic Modeling written by Nicolas Lanchier and published by Springer. This book was released on 2017-01-27 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Three coherent parts form the material covered in this text, portions of which have not been widely covered in traditional textbooks. In this coverage the reader is quickly introduced to several different topics enriched with 175 exercises which focus on real-world problems. Exercises range from the classics of probability theory to more exotic research-oriented problems based on numerical simulations. Intended for graduate students in mathematics and applied sciences, the text provides the tools and training needed to write and use programs for research purposes. The first part of the text begins with a brief review of measure theory and revisits the main concepts of probability theory, from random variables to the standard limit theorems. The second part covers traditional material on stochastic processes, including martingales, discrete-time Markov chains, Poisson processes, and continuous-time Markov chains. The theory developed is illustrated by a variety of examples surrounding applications such as the gambler’s ruin chain, branching processes, symmetric random walks, and queueing systems. The third, more research-oriented part of the text, discusses special stochastic processes of interest in physics, biology, and sociology. Additional emphasis is placed on minimal models that have been used historically to develop new mathematical techniques in the field of stochastic processes: the logistic growth process, the Wright –Fisher model, Kingman’s coalescent, percolation models, the contact process, and the voter model. Further treatment of the material explains how these special processes are connected to each other from a modeling perspective as well as their simulation capabilities in C and MatlabTM.
Book Synopsis Stochastic Modeling of Scientific Data by : Peter Guttorp
Download or read book Stochastic Modeling of Scientific Data written by Peter Guttorp and published by CRC Press. This book was released on 2018-03-29 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stochastic Modeling of Scientific Data combines stochastic modeling and statistical inference in a variety of standard and less common models, such as point processes, Markov random fields and hidden Markov models in a clear, thoughtful and succinct manner. The distinguishing feature of this work is that, in addition to probability theory, it contains statistical aspects of model fitting and a variety of data sets that are either analyzed in the text or used as exercises. Markov chain Monte Carlo methods are introduced for evaluating likelihoods in complicated models and the forward backward algorithm for analyzing hidden Markov models is presented. The strength of this text lies in the use of informal language that makes the topic more accessible to non-mathematicians. The combinations of hard science topics with stochastic processes and their statistical inference puts it in a new category of probability textbooks. The numerous examples and exercises are drawn from astronomy, geology, genetics, hydrology, neurophysiology and physics.
Book Synopsis Stochastic Modelling for Systems Biology, Second Edition by : Darren J. Wilkinson
Download or read book Stochastic Modelling for Systems Biology, Second Edition written by Darren J. Wilkinson and published by CRC Press. This book was released on 2011-11-09 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first edition of Stochastic Modelling for Systems Biology, there have been many interesting developments in the use of "likelihood-free" methods of Bayesian inference for complex stochastic models. Re-written to reflect this modern perspective, this second edition covers everything necessary for a good appreciation of stochastic kinetic modelling of biological networks in the systems biology context. Keeping with the spirit of the first edition, all of the new theory is presented in a very informal and intuitive manner, keeping the text as accessible as possible to the widest possible readership. New in the Second Edition All examples have been updated to Systems Biology Markup Language Level 3 All code relating to simulation, analysis, and inference for stochastic kinetic models has been re-written and re-structured in a more modular way An ancillary website provides links, resources, errata, and up-to-date information on installation and use of the associated R package More background material on the theory of Markov processes and stochastic differential equations, providing more substance for mathematically inclined readers Discussion of some of the more advanced concepts relating to stochastic kinetic models, such as random time change representations, Kolmogorov equations, Fokker-Planck equations and the linear noise approximation Simple modelling of "extrinsic" and "intrinsic" noise An effective introduction to the area of stochastic modelling in computational systems biology, this new edition adds additional mathematical detail and computational methods that will provide a stronger foundation for the development of more advanced courses in stochastic biological modelling.
Book Synopsis Stochastic Processes and Applications in Biology and Medicine: Theory by : Marius Iosifescu
Download or read book Stochastic Processes and Applications in Biology and Medicine: Theory written by Marius Iosifescu and published by . This book was released on 1973 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: A stray dog is constantly frustrated in her quest for a bone. Turning the narrower pages reveals hidden portions of the illustrations.
Book Synopsis Stochastic Approaches for Systems Biology by : Mukhtar Ullah
Download or read book Stochastic Approaches for Systems Biology written by Mukhtar Ullah and published by Springer Science & Business Media. This book was released on 2011-07-12 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook focuses on stochastic analysis in systems biology containing both the theory and application. While the authors provide a review of probability and random variables, subsequent notions of biochemical reaction systems and the relevant concepts of probability theory are introduced side by side. This leads to an intuitive and easy-to-follow presentation of stochastic framework for modeling subcellular biochemical systems. In particular, the authors make an effort to show how the notion of propensity, the chemical master equation and the stochastic simulation algorithm arise as consequences of the Markov property. The text contains many illustrations, examples and exercises to illustrate the ideas and methods that are introduced. Matlab code is also provided where appropriate. Additionally, the cell cycle is introduced as a more complex case study. Senior undergraduate and graduate students in mathematics and physics as well as researchers working in the area of systems biology, bioinformatics and related areas will find this text useful.
Book Synopsis An Introduction to Stochastic Modeling by : Howard M. Taylor
Download or read book An Introduction to Stochastic Modeling written by Howard M. Taylor and published by Academic Press. This book was released on 2014-05-10 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Stochastic Modeling provides information pertinent to the standard concepts and methods of stochastic modeling. This book presents the rich diversity of applications of stochastic processes in the sciences. Organized into nine chapters, this book begins with an overview of diverse types of stochastic models, which predicts a set of possible outcomes weighed by their likelihoods or probabilities. This text then provides exercises in the applications of simple stochastic analysis to appropriate problems. Other chapters consider the study of general functions of independent, identically distributed, nonnegative random variables representing the successive intervals between renewals. This book discusses as well the numerous examples of Markov branching processes that arise naturally in various scientific disciplines. The final chapter deals with queueing models, which aid the design process by predicting system performance. This book is a valuable resource for students of engineering and management science. Engineers will also find this book useful.
Book Synopsis Stochastic processes and applications in biology and medicine II by : Marius Iosifescu
Download or read book Stochastic processes and applications in biology and medicine II written by Marius Iosifescu and published by Springer. This book was released on 2011-12-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a revised and enlarged version of Chapter 3 of. a book with the same title, published in Romanian in 1968. The revision resulted in a new book which has been divided into two of the large amount of new material. The whole book parts because is intended to introduce mathematicians and biologists with a strong mathematical background to the study of stochastic processes and their applications in biological sciences. It is meant to serve both as a textbook and a survey of recent developments. Biology studies complex situations and therefore needs skilful methods of abstraction. Stochastic models, being both vigorous in their specification and flexible in their manipulation, are the most suitable tools for studying such situations. This circumstance deter mined the writing of this volume which represents a comprehensive cross section of modern biological problems on the theory of stochastic processes. Because of the way some specific problems have been treat ed, this volume may also be useful to research scientists in any other field of science, interested in the possibilities and results of stochastic modelling. To understand the material presented, the reader needs to be acquainted with probability theory, as given in a sound introductory course, and be capable of abstraction.
Book Synopsis Deterministic Versus Stochastic Modelling in Biochemistry and Systems Biology by : Paola Lecca
Download or read book Deterministic Versus Stochastic Modelling in Biochemistry and Systems Biology written by Paola Lecca and published by Elsevier. This book was released on 2013-04-09 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stochastic kinetic methods are currently considered to be the most realistic and elegant means of representing and simulating the dynamics of biochemical and biological networks. Deterministic versus stochastic modelling in biochemistry and systems biology introduces and critically reviews the deterministic and stochastic foundations of biochemical kinetics, covering applied stochastic process theory for application in the field of modelling and simulation of biological processes at the molecular scale. Following an overview of deterministic chemical kinetics and the stochastic approach to biochemical kinetics, the book goes onto discuss the specifics of stochastic simulation algorithms, modelling in systems biology and the structure of biochemical models. Later chapters cover reaction-diffusion systems, and provide an analysis of the Kinfer and BlenX software systems. The final chapter looks at simulation of ecodynamics and food web dynamics. Introduces mathematical concepts and formalisms of deterministic and stochastic modelling through clear and simple examples Presents recently developed discrete stochastic formalisms for modelling biological systems and processes Describes and applies stochastic simulation algorithms to implement a stochastic formulation of biochemical and biological kinetics
Book Synopsis Introduction to Stochastic Models by : Roe Goodman
Download or read book Introduction to Stochastic Models written by Roe Goodman and published by Courier Corporation. This book was released on 2006-01-01 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Newly revised by the author, this undergraduate-level text introduces the mathematical theory of probability and stochastic processes. Using both computer simulations and mathematical models of random events, it comprises numerous applications to the physical and biological sciences, engineering, and computer science. Subjects include sample spaces, probabilities distributions and expectations of random variables, conditional expectations, Markov chains, and the Poisson process. Additional topics encompass continuous-time stochastic processes, birth and death processes, steady-state probabilities, general queuing systems, and renewal processes. Each section features worked examples, and exercises appear at the end of each chapter, with numerical solutions at the back of the book. Suggestions for further reading in stochastic processes, simulation, and various applications also appear at the end.
Book Synopsis Stochastic Modeling of Scientific Data by : Peter Guttorp
Download or read book Stochastic Modeling of Scientific Data written by Peter Guttorp and published by CRC Press. This book was released on 2018-03-29 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stochastic Modeling of Scientific Data combines stochastic modeling and statistical inference in a variety of standard and less common models, such as point processes, Markov random fields and hidden Markov models in a clear, thoughtful and succinct manner. The distinguishing feature of this work is that, in addition to probability theory, it contains statistical aspects of model fitting and a variety of data sets that are either analyzed in the text or used as exercises. Markov chain Monte Carlo methods are introduced for evaluating likelihoods in complicated models and the forward backward algorithm for analyzing hidden Markov models is presented. The strength of this text lies in the use of informal language that makes the topic more accessible to non-mathematicians. The combinations of hard science topics with stochastic processes and their statistical inference puts it in a new category of probability textbooks. The numerous examples and exercises are drawn from astronomy, geology, genetics, hydrology, neurophysiology and physics.
