Stem Cells In Endocrinology

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Stem Cells in Endocrinology

Author : Linda B. Lester
Publisher : Springer Science & Business Media
ISBN 13 : 1592599001
Total Pages : 277 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Stem Cells in Endocrinology by : Linda B. Lester

Download or read book Stem Cells in Endocrinology written by Linda B. Lester and published by Springer Science & Business Media. This book was released on 2007-11-06 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: A critical review by prominent experts of both the cutting-edge of stem cell biology and the application of stem cells to endocrine diseases, including diabetes, infertility, and liver-associated metabolic disorders. The authors discuss current research to modify stem cells, develop an endocrine-like cell, and use adult bone marrow stem cells to treat autoimmune diseases, including endocrine-based autoimmune diseases. Topics of interest include a review of all stem cell subtypes and their characteristics, approaches to promoting endocrine development from stem cells, and evidence for endocrine cell function from stem cells. The authors also outline how best to develop preclinical studies that will determine the safety and efficacy of stem cell therapies for endocrine disorders.

Stem Cells in Neuroendocrinology

Author : Donald Pfaff
Publisher : Springer
ISBN 13 : 3319416030
Total Pages : 163 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Stem Cells in Neuroendocrinology by : Donald Pfaff

Download or read book Stem Cells in Neuroendocrinology written by Donald Pfaff and published by Springer. This book was released on 2016-07-26 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume starts with an elementary introduction covering stem cell methodologies used to produce specific types of neurons, possibilities for their therapeutic use, and warnings of technical problems. In addition the authors report successes in achieving the derivation of a specific type of neuron. The dopamine neuron offers an important example and is discussed in more detail. Additional chapters cover problems obviously approachable with cells derived from stem cells, including their need in surgeries for pituitary cancers. The last chapter provides an overview of this particular field of research and presents a vision for its future directions.

Hormones and Stem Cells

Author : Gerald Litwack
Publisher : Academic Press
ISBN 13 : 0323855512
Total Pages : 456 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Hormones and Stem Cells by : Gerald Litwack

Download or read book Hormones and Stem Cells written by Gerald Litwack and published by Academic Press. This book was released on 2021-03-20 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vitamins and Hormones serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Vitamins and Hormones series Includes the latest information on Hormones and Synapse

Cellular Endocrinology in Health and Disease

Author : Alfredo Ulloa-Aguirre
Publisher : Academic Press
ISBN 13 : 012819801X
Total Pages : 486 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Cellular Endocrinology in Health and Disease by : Alfredo Ulloa-Aguirre

Download or read book Cellular Endocrinology in Health and Disease written by Alfredo Ulloa-Aguirre and published by Academic Press. This book was released on 2021-02-19 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular Endocrinology in Health and Disease, Second Edition, describes the underlying basis of endocrine function, providing an important tool to understand the fundamentals of endocrine diseases. Delivering a comprehensive review of the basic science of endocrinology, from cell biology to human disease, this work explores and dissects the function of a number of cellular systems. The new edition provides an understanding of how endocrine glands function by integrating information resulting in biological effects on both local and systemic levels, also providing new information on the molecular physiopathogenesis of endocrine neoplasic cells. The new edition expands the most used chapters from the first edition and proposes a series of substitutions and additions to the table of contents. New chapters cover signaling, brown adipose tissue, hypothalamic cell models, cellular basis of insulin resistance, genetics and epigenetics of neuroendocrine tumors, and a series of chapters on endocrine-related cancer. Providing content that crosses disciplines, Cellular Endocrinology in Health and Disease, Second Edition, details how cellular endocrine function contributes to system physiology and mediates endocrine disorders. A methods section proves novel and useful approaches across research focus that will be attractive to medical students, residents, and specialists in the field of endocrinology, as well as to those interested in cellular regulation. Editors Alfredo Ulloa-Aguirre and Ya-Xiong Tao, experts in molecular and cellular aspects of endocrinology, deliver contributions carefully selected for relevance, impact, and clarity of expression from leading field experts Explores endocrine cells biology in normal and pathologic conditions Covers new aspects of endocrine cell function in distinct tissues Provides a view into the biological effect in local and systemic levels 15 new chapters covering the recent developments in the field

Cancer Stem Cells in Endocrine Tumors

Author : Giorgio Stassi
Publisher : Frontiers Media SA
ISBN 13 : 2889712567
Total Pages : 122 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Cancer Stem Cells in Endocrine Tumors by : Giorgio Stassi

Download or read book Cancer Stem Cells in Endocrine Tumors written by Giorgio Stassi and published by Frontiers Media SA. This book was released on 2021-09-01 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pancreatic Stem Cells

Author : Juan Domínguez-Bendala
Publisher : Springer Science & Business Media
ISBN 13 : 1607611325
Total Pages : 157 pages
Book Rating : 4.6/5 (76 download)

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Book Synopsis Pancreatic Stem Cells by : Juan Domínguez-Bendala

Download or read book Pancreatic Stem Cells written by Juan Domínguez-Bendala and published by Springer Science & Business Media. This book was released on 2012-02-10 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the discovery of Pdx1, the first “master gene” of pancreatic development, to the most recent findings on the role of microRNAs in beta cell homeostasis, the last fifteen years have seen an unprecedented advance in our understanding of the precise development and organization of the many different cell types that make up the pancreas. It is now widely acknowledged that the therapeutic differentiation of stem cells into pancreatic cells is an ambitious endeavor that will not succeed without a thorough understanding of the molecular processes underlying the native development of the organ. This book, aimed at experts and students alike, offers a comprehensive review of the state of the art in both pancreatic development and regeneration. The many strategies to differentiate adult and embryonic stem cells into pancreatic beta cells are also discussed in the context of potential therapeutic interventions for type I diabetes.

Stem Cells in Neuroendocrinology

Author : Yves Christen
Publisher :
ISBN 13 : 9781013267376
Total Pages : 162 pages
Book Rating : 4.2/5 (673 download)

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Book Synopsis Stem Cells in Neuroendocrinology by : Yves Christen

Download or read book Stem Cells in Neuroendocrinology written by Yves Christen and published by . This book was released on 2020-10-08 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume starts with an elementary introduction covering stem cell methodologies used to produce specific types of neurons, possibilities for their therapeutic use, and warnings of technical problems. In addition the authors report successes in achieving the derivation of a specific type of neuron. The dopamine neuron offers an important example and is discussed in more detail. Additional chapters cover problems obviously approachable with cells derived from stem cells, including their need in surgeries for pituitary cancers. The last chapter provides an overview of this particular field of research and presents a vision for its future directions. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

Stem Cells and Prostate Cancer

Author : Scott D. Cramer
Publisher : Springer
ISBN 13 : 9781493900947
Total Pages : 0 pages
Book Rating : 4.9/5 (9 download)

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Book Synopsis Stem Cells and Prostate Cancer by : Scott D. Cramer

Download or read book Stem Cells and Prostate Cancer written by Scott D. Cramer and published by Springer. This book was released on 2015-02-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent evidence demonstrates that normal prostate tissue contains stem cells. There is also accumulating evidence that prostate cancer contains a population of cells with stem cell-like characteristics referred to as cancer stem cells, or tumor initiating cells. Both the normal prostate stem cell and cancer stem cell populations have important implications for the generation, therapeutic targeting, and prevention of prostate cancer. The purpose of this book is to explore the role of stem cells in prostate cancer, which is becoming an increasingly hot trend in cancer research.

Stem Cell Therapy for Diabetes

Author : Shimon Efrat
Publisher : Springer Science & Business Media
ISBN 13 : 1607613662
Total Pages : 294 pages
Book Rating : 4.6/5 (76 download)

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Book Synopsis Stem Cell Therapy for Diabetes by : Shimon Efrat

Download or read book Stem Cell Therapy for Diabetes written by Shimon Efrat and published by Springer Science & Business Media. This book was released on 2009-12-01 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cell Therapy for Diabetes, one of the latest installments of the Stem Cell Biology and Regenerative Medicine series, reviews the three main approaches for generation of sufficient numbers of insulin-producing cells for restoration of an adequate beta-cell mass: beta-cell expansion, stem-cell differentiation, and nuclear reprogramming. Adeptly collecting the research of the leading scientists in the field, Stem Cell Therapy for Diabetes compares the merits of employing autologous versus banked allogeneic cell sources for generation of surrogate beta cells, and addresses tissue engineering and ways for cell protection from recurring autoimmunity and graft rejection. Stem Cell Therapy for Diabetes provides essential reading for those especially interested in tracking the progress in applying of one of the most exciting new developments in bio-medicine towards a cure for diabetes.

The Neuroendocrine Leydig Cells and their Stem Cell Progenitors, the Pericytes

Author : Michail S. Davidoff
Publisher : Springer Science & Business Media
ISBN 13 : 3642005136
Total Pages : 157 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis The Neuroendocrine Leydig Cells and their Stem Cell Progenitors, the Pericytes by : Michail S. Davidoff

Download or read book The Neuroendocrine Leydig Cells and their Stem Cell Progenitors, the Pericytes written by Michail S. Davidoff and published by Springer Science & Business Media. This book was released on 2009-07-15 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: cells, and the testicular localization of the intermediate filament protein nestin, known to be expressed in neural stem cells, by our group was the first step to define mural cells (pericytes and vascular smooth muscle cells) of the testis microvascu- ture as the stem/progenitor cells of the adult Leydig cells. In summary, we were able to demonstrate specific proliferation of vascular progenitors and their subsequent transdifferentiation into steroidogenic Leydig cells, which – in addition – rapidly acquire neuronal and glial properties. Since both newly developed fetal and adult Leydig cell populations show the same features, a common origin of both popu- tions seems likely. Pericytes are distributed throughout the body, and there is convincing evidence for their stem/progenitor cell properties in diverse organs. Under appropriate (locally defined) conditions these pericytes, which reside in the vascular stem cell niche as dormant stem cells, become activated, proliferate, migrate and differentiate towards different somatic cell types of the body. Since most mesenchymal stem/ progenitor cell types exhibit essential similarity to pericytes and certain mesenchymal stem cells represent pericyte descendants, we propose that mesenchymal stem cells in the perivascular niche are daughter cells of pericytes. Thus, pericytes are promising candidates for ancestor cells of all adult stem cells in the organism. There is strong evidence that early stem cells (cells arising during embryogenesis), such as the pericytes, exhibit both mesodermal and neural progeny, which might explain the neuroendocrine properties of the Leydig cells.

Pancreatic Stem Cells

Author : Juan Domínguez-Bendala
Publisher : Humana Press
ISBN 13 : 9781607611363
Total Pages : 154 pages
Book Rating : 4.6/5 (113 download)

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Book Synopsis Pancreatic Stem Cells by : Juan Domínguez-Bendala

Download or read book Pancreatic Stem Cells written by Juan Domínguez-Bendala and published by Humana Press. This book was released on 2010-11-16 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the discovery of Pdx1, the first “master gene” of pancreatic development, to the most recent findings on the role of microRNAs in beta cell homeostasis, the last fifteen years have seen an unprecedented advance in our understanding of the precise development and organization of the many different cell types that make up the pancreas. It is now widely acknowledged that the therapeutic differentiation of stem cells into pancreatic cells is an ambitious endeavor that will not succeed without a thorough understanding of the molecular processes underlying the native development of the organ. This book, aimed at experts and students alike, offers a comprehensive review of the state of the art in both pancreatic development and regeneration. The many strategies to differentiate adult and embryonic stem cells into pancreatic beta cells are also discussed in the context of potential therapeutic interventions for type I diabetes.

Textbook of Diabetes

Author : Richard I. G. Holt
Publisher : John Wiley & Sons
ISBN 13 : 1118912020
Total Pages : 1104 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Textbook of Diabetes by : Richard I. G. Holt

Download or read book Textbook of Diabetes written by Richard I. G. Holt and published by John Wiley & Sons. This book was released on 2017-03-06 with total page 1104 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its fifth edition, the Textbook of Diabetes has established itself as the modern, well-illustrated, international guide to diabetes. Sensibly organized and easy to navigate, with exceptional illustrations, the Textbook hosts an unrivalled blend of clinical and scientific content. Highly-experienced editors from across the globe assemble an outstanding set of international contributors who provide insight on new developments in diabetes care and information on the latest treatment modalities used around the world. The fifth edition features an array of brand new chapters, on topics including: Ischaemic Heart Disease Glucagon in Islet Regulation Microbiome and Diabetes Diabetes and Non-Alcoholic Fatty Liver Disease Diabetes and Cancer End of Life Care in Diabetes as well as a new section on Psychosocial aspects of diabetes. In addition, all existing chapters are fully revised with the very latest developments, including the most recent guidelines from the ADA, EASD, DUK and NICE. Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates Via the companion website, readers can access a host of additional online materials such as: 200 interactive MCQ's to allow readers to self-assess their clinical knowledge every figure from the book, available to download into presentations fully searchable chapter pdfs Once again, Textbook of Diabetes provides endocrinologists and diabetologists with a fresh, comprehensive and multi-media clinical resource to consult time and time again.

Genomics, Proteomics, and Metabolomics

Author : Babak Arjmand
Publisher : Springer Nature
ISBN 13 : 3030277275
Total Pages : 199 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Genomics, Proteomics, and Metabolomics by : Babak Arjmand

Download or read book Genomics, Proteomics, and Metabolomics written by Babak Arjmand and published by Springer Nature. This book was released on 2019-11-14 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides thorough coverage of high-throughput OMICs technologies for the monitoring of stem cells and regenerative medicine. Specific topics covered include the genomics, proteomics, and metabolomics aspects of regenerative medicine, metabolic profiling of mesenchymal stem cells, genome profiling of mesenchymal stem cells, OMICs monitoring of stem cell-derived exosomes, stem cell proteomics, lipidomics, OMICs profiling of cancer (stem) cells, and finally ethical considerations of OMICs-based investigations. Chapters are authored by world-renowned scientists who have valuable expertise in the field of OMICs and regenerative medicine. Genomics, Proteomics, and Metabolomics: Stem Cells Monitoring in Regenerative Medicine, part of Springer’s Stem Cell Biology and Regenerative Medicine series, is essential reading for researchers, clinicians, biologists, biochemists, and pharmaceutical experts conducting research in the fields of stem cell biology, molecular aspects of stem cell research, tissue engineering, regenerative medicine, cellular therapy, OMICs, bioinformatics, and ethics.

Induction of Stem Cells to Adopt an Endocrine

Author : Joseph LeDoux
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (696 download)

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Book Synopsis Induction of Stem Cells to Adopt an Endocrine by : Joseph LeDoux

Download or read book Induction of Stem Cells to Adopt an Endocrine written by Joseph LeDoux and published by . This book was released on 2006 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Stem Cell Surgery Trials in Heart Failure and Diabetes

Author : Jeffrey N. Weiss
Publisher :
ISBN 13 : 9783030780111
Total Pages : 0 pages
Book Rating : 4.7/5 (81 download)

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Book Synopsis Stem Cell Surgery Trials in Heart Failure and Diabetes by : Jeffrey N. Weiss

Download or read book Stem Cell Surgery Trials in Heart Failure and Diabetes written by Jeffrey N. Weiss and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the application of stem cell surgery for diabetes and heart failure. Organized into two sections, the first identifies and summarizes the current worldwide stem cell trials for heart failure. Subsequent chapters in part two analyze the current worldwide stem cell trials in patients with Diabetes Mellitus. Both sections utilize studies that include non-expanded stem cells; each study is grouped by stem cell type and geographic location. Stem Cell Surgery Trials in Diabetes and Heart Failure is a comprehensive, convenient reference for cardiologists, endocrinologists, internists, and family physicians. .

Transgenic Models in Endocrinology

Author : Maria G. Castro
Publisher : Springer Science & Business Media
ISBN 13 : 1461516331
Total Pages : 294 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Transgenic Models in Endocrinology by : Maria G. Castro

Download or read book Transgenic Models in Endocrinology written by Maria G. Castro and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: The dramatic recent expansion in genomic information has motivated the development of new approaches to characterize gene expression and function. A critical issue for both basic and clinical endocrinologists is the physiological role of genes involved in regulating endocrine functions. Transgenic technologies allow the translation of genotypic information into specific phenotypes by using gene overexpression or loss of specific gene functions. Murine functional genomics is thus of central importance in modem biomedical endocrine research. Although mice are at present, the preferred mammalian species for genetic manipulations because of the availability of pluripotent embryonic. stem cells and inbred strains and the relatively low breeding and maintenance costs, transgenic rats have also been generated and used to study endocrine physiology. The two basic techniques used in the creation of transgenic animal models are integration of foreign DNA into a fertilized oocyte by random chromosomal insertion and homologous recombination in embryonic stem cells that are then introduced into zygotes. Transgenic mice and rats serve as sophisticted tools to probe protein function, as models of human disease, and as hosts for the testing of gene replacement and other therapies. Embryonic stem cell libraries for mouse gene deletion are being developed, which will make it possible to generate knockout mice rapidly and without the need to analyze gene structure, construct targeting vectors, and screen embryonic stem cell clones. A novel approach to transgenesis for the expression of DNA within adult differentiated neuroendocrine cells in vivo is using viral vectors.

Human Embryonic Stem Cells

Author : Jon Odorico
Publisher : Garland Science
ISBN 13 : 0203487346
Total Pages : 391 pages
Book Rating : 4.2/5 (34 download)

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Book Synopsis Human Embryonic Stem Cells by : Jon Odorico

Download or read book Human Embryonic Stem Cells written by Jon Odorico and published by Garland Science. This book was released on 2004-02-01 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first successful isolation and cultivation of human embryonic stem cells at the University of Wisconsin, Madison in 1998, there has been high levels of both interest and controversy in this area of research. This book provides a concise overview of an exciting field, covering the characteristics of both human embryonic stem cells and pluripotent stem cells from other human cell lineages. The following chapters describe state-of-the-art differentiation and characterization of specific ectoderm, mesoderm and endoderm-derived lineages from human embryonic stem cells, emphasizing how these can be used to study human developmental mechanisms. A further chapter discusses genetic manipulation of human ES cells. The concluding section covers therapeutic applications of human ES cells, as well as addressing the ethical and legal issues that this research have raised.