Statistical Analysis of Clinical Data on a Pocket Calculator, Part 2

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Publisher : Springer Science & Business Media
ISBN 13 : 9400747047
Total Pages : 79 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Statistical Analysis of Clinical Data on a Pocket Calculator, Part 2 by : Ton J. Cleophas

Download or read book Statistical Analysis of Clinical Data on a Pocket Calculator, Part 2 written by Ton J. Cleophas and published by Springer Science & Business Media. This book was released on 2012-06-28 with total page 79 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first part of this title contained all statistical tests relevant to starting clinical investigations, and included tests for continuous and binary data, power, sample size, multiple testing, variability, confounding, interaction, and reliability. The current part 2 of this title reviews methods for handling missing data, manipulated data, multiple confounders, predictions beyond observation, uncertainty of diagnostic tests, and the problems of outliers. Also robust tests, non-linear modeling , goodness of fit testing, Bhatacharya models, item response modeling, superiority testing, variability testing, binary partitioning for CART (classification and regression tree) methods, meta-analysis, and simple tests for incident analysis and unexpected observations at the workplace and reviewed. Each test method is reported together with (1) a data example from practice, (2) all steps to be taken using a scientific pocket calculator, and (3) the main results and their interpretation. Although several of the described methods can also be carried out with the help of statistical software, the latter procedure will be considerably slower. Both part 1 and 2 of this title consist of a minimum of text and this will enhance the process of mastering the methods. Yet the authors recommend that for a better understanding of the test procedures the books be used together with the same authors' textbook "Statistics Applied to Clinical Studies" 5th edition edited 2012, by Springer Dordrecht Netherlands. More complex data files like data files with multiple treatment modalities or multiple predictor variables can not be analyzed with a pocket calculator. We recommend that the small books "SPSS for starters", Part 1 and 2 (Springer, Dordrecht, 2010, and 2012) from the same authors be used as a complementary help for the readers' benefit.

SPSS for Starters, Part 2

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Publisher : Springer Science & Business Media
ISBN 13 : 9400748043
Total Pages : 105 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis SPSS for Starters, Part 2 by : Ton J. Cleophas

Download or read book SPSS for Starters, Part 2 written by Ton J. Cleophas and published by Springer Science & Business Media. This book was released on 2012-07-09 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first part of this title contained all statistical tests that are relevant for starters on SPSS, and included standard parametric and non-parametric tests for continuous and binary variables, regression methods, trend tests, and reliability and validity assessments of diagnostic tests. The current part 2 of this title reviews multistep methods, multivariate models, assessments of missing data, performance of diagnostic tests, meta-regression, Poisson regression, confounding and interaction, and survival analyses using log tests and segmented time-dependent Cox regression. Methods for assessing non linear models, data seasonality, distribution free methods, including Monte Carlo methods and artificial intelligence, and robust tests are also covered. Each method of testing is explained using a data example from clinical practice,including every step in SPSS, and a text with interpretations of the results and hints convenient for data reporting. In order to facilitate the use of this cookbook the data files of the examples is made available by the editor through extras.springer.com. Both part 1 and 2 of this title contain a minima amount of text and maximal technical details, but we believe that this property will not refrain students from mastering the SPSS software systematics, and that, instead, it will be a help to that aim. Yet, we recommend that it will used together with the textbook "Statistics Applied to Clinical Trials" (5th edition, Springer, Dordrecht 2012) and the e-books "Statistics on a Pocket Calculator Part 1 and 2 (Springer, Dordrecht, 2011 and 2012) from the same authors.

Clinical Data Analysis on a Pocket Calculator

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Publisher : Springer
ISBN 13 : 3319271040
Total Pages : 328 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Clinical Data Analysis on a Pocket Calculator by : Ton J. Cleophas

Download or read book Clinical Data Analysis on a Pocket Calculator written by Ton J. Cleophas and published by Springer. This book was released on 2016-01-22 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: In medical and health care the scientific method is little used, and statistical software programs are experienced as black box programs producing lots of p-values, but little answers to scientific questions. The pocket calculator analyses appears to be, particularly, appreciated, because they enable medical and health professionals and students for the first time to understand the scientific methods of statistical reasoning and hypothesis testing. So much so, that it can start something like a new dimension in their professional world. In addition, a number of statistical methods like power calculations and required sample size calculations can be performed more easily on a pocket calculator, than using a software program. Also, there are some specific advantages of the pocket calculator method. You better understand what you are doing. The pocket calculator works faster, because far less steps have to be taken, averages can be used. The current nonmathematical book is complementary to the nonmathematical "SPSS for Starters and 2nd Levelers" (Springer Heidelberg Germany 2015, from the same authors), and can very well be used as its daily companion.

Intelligent Tools for Building a Scientific Information Platform: From Research to Implementation

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Publisher : Springer
ISBN 13 : 3319047140
Total Pages : 297 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Intelligent Tools for Building a Scientific Information Platform: From Research to Implementation by : Robert Bembenik

Download or read book Intelligent Tools for Building a Scientific Information Platform: From Research to Implementation written by Robert Bembenik and published by Springer. This book was released on 2014-07-08 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a selection of results obtained within three years of research performed under SYNAT—a nation-wide scientific project aiming at creating an infrastructure for scientific content storage and sharing for academia, education and open knowledge society in Poland. The book is intended to be the last of the series related to the SYNAT project. The previous books, titled “Intelligent Tools for Building a Scientific Information Platform” and “Intelligent Tools for Building a Scientific Information Platform: Advanced Architectures and Solutions”, were published as volumes 390 and 467 in Springer's Studies in Computational Intelligence. Its contents is based on the SYNAT 2013 Workshop held in Warsaw. The papers included in this volume present an overview and insight into information retrieval, repository systems, text processing, ontology-based systems, text mining, multimedia data processing and advanced software engineering, addressing the problems of implementing intelligent tools for building a scientific information platform.

Bayesian Networks In Fault Diagnosis: Practice And Application

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Publisher : World Scientific
ISBN 13 : 9813271507
Total Pages : 418 pages
Book Rating : 4.8/5 (132 download)

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Book Synopsis Bayesian Networks In Fault Diagnosis: Practice And Application by : Baoping Cai

Download or read book Bayesian Networks In Fault Diagnosis: Practice And Application written by Baoping Cai and published by World Scientific. This book was released on 2018-08-24 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fault diagnosis is useful for technicians to detect, isolate, identify faults, and troubleshoot. Bayesian network (BN) is a probabilistic graphical model that effectively deals with various uncertainty problems. This model is increasingly utilized in fault diagnosis.This unique compendium presents bibliographical review on the use of BNs in fault diagnosis in the last decades with focus on engineering systems. Subsequently, eleven important issues in BN-based fault diagnosis methodology, such as BN structure modeling, BN parameter modeling, BN inference, fault identification, validation, and verification are discussed in various cases.Researchers, professionals, academics and graduate students will better understand the theory and application, and benefit those who are keen to develop real BN-based fault diagnosis system.

SPSS for Starters and 2nd Levelers

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Publisher : Springer
ISBN 13 : 3319206001
Total Pages : 361 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis SPSS for Starters and 2nd Levelers by : Ton J. Cleophas

Download or read book SPSS for Starters and 2nd Levelers written by Ton J. Cleophas and published by Springer. This book was released on 2015-10-14 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unique point of this book is its low threshold, textually simple and at the same time full of self-assessment opportunities. Other unique points are the succinctness of the chapters with 3 to 6 pages, the presence of entire-commands-texts of the statistical methodologies reviewed and the fact that dull scientific texts imposing an unnecessary burden on busy and jaded professionals have been left out. For readers requesting more background, theoretical and mathematical information a note section with references is in each chapter. The first edition in 2010 was the first publication of a complete overview of SPSS methodologies for medical and health statistics. Well over 100,000 copies of various chapters were sold within the first year of publication. Reasons for a rewrite were four. First, many important comments from readers urged for a rewrite. Second, SPSS has produced many updates and upgrades, with relevant novel and improved methodologies. Third, the authors felt that the chapter texts needed some improvements for better readability: chapters have now been classified according the outcome data helpful for choosing your analysis rapidly, a schematic overview of data, and explanatory graphs have been added. Fourth, current data are increasingly complex and many important methods for analysis were missing in the first edition. For that latter purpose some more advanced methods seemed unavoidable, like hierarchical loglinear methods, gamma and Tweedie regressions and random intercept analyses. In order for the contents of the book to remain covered by the title, the authors renamed the book: SPSS for Starters and 2nd Levelers. Special care was, nonetheless, taken to keep things as simple as possible, simple menu commands are given. The arithmetic is still of a no-more-than high-school level. Step-by-step analyses of different statistical methodologies are given with the help of 60 SPSS data files available through the internet. Because of the lack of time of this busy group of people, the authors have given every effort to produce a text as succinct as possible.

Cumulated Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 1448 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1975 with total page 1448 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Statistical Analysis of Clinical Data on a Pocket Calculator, Part 2

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Author :
Publisher : Springer
ISBN 13 : 9789400747036
Total Pages : 0 pages
Book Rating : 4.7/5 (47 download)

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Book Synopsis Statistical Analysis of Clinical Data on a Pocket Calculator, Part 2 by : Ton J. Cleophas

Download or read book Statistical Analysis of Clinical Data on a Pocket Calculator, Part 2 written by Ton J. Cleophas and published by Springer. This book was released on 2012-06-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first part of this title contained all statistical tests relevant to starting clinical investigations, and included tests for continuous and binary data, power, sample size, multiple testing, variability, confounding, interaction, and reliability. The current part 2 of this title reviews methods for handling missing data, manipulated data, multiple confounders, predictions beyond observation, uncertainty of diagnostic tests, and the problems of outliers. Also robust tests, non-linear modeling , goodness of fit testing, Bhatacharya models, item response modeling, superiority testing, variability testing, binary partitioning for CART (classification and regression tree) methods, meta-analysis, and simple tests for incident analysis and unexpected observations at the workplace and reviewed. Each test method is reported together with (1) a data example from practice, (2) all steps to be taken using a scientific pocket calculator, and (3) the main results and their interpretation. Although several of the described methods can also be carried out with the help of statistical software, the latter procedure will be considerably slower. Both part 1 and 2 of this title consist of a minimum of text and this will enhance the process of mastering the methods. Yet the authors recommend that for a better understanding of the test procedures the books be used together with the same authors' textbook "Statistics Applied to Clinical Studies" 5th edition edited 2012, by Springer Dordrecht Netherlands. More complex data files like data files with multiple treatment modalities or multiple predictor variables can not be analyzed with a pocket calculator. We recommend that the small books "SPSS for starters", Part 1 and 2 (Springer, Dordrecht, 2010, and 2012) from the same authors be used as a complementary help for the readers' benefit.

Modern Bayesian Statistics in Clinical Research

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Publisher : Springer
ISBN 13 : 3319927477
Total Pages : 193 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Modern Bayesian Statistics in Clinical Research by : Ton J. Cleophas

Download or read book Modern Bayesian Statistics in Clinical Research written by Ton J. Cleophas and published by Springer. This book was released on 2018-07-31 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current textbook has been written as a help to medical / health professionals and students for the study of modern Bayesian statistics, where posterior and prior odds have been replaced with posterior and prior likelihood distributions. Why may likelihood distributions better than normal distributions estimate uncertainties of statistical test results? Nobody knows for sure, and the use of likelihood distributions instead of normal distributions for the purpose has only just begun, but already everybody is trying and using them. SPSS statistical software version 25 (2017) has started to provide a combined module entitled Bayesian Statistics including almost all of the modern Bayesian tests (Bayesian t-tests, analysis of variance (anova), linear regression, crosstabs etc.). Modern Bayesian statistics is based on biological likelihoods, and may better fit clinical data than traditional tests based normal distributions do. This is the first edition to systematically imply modern Bayesian statistics in traditional clinical data analysis. This edition also demonstrates that Markov Chain Monte Carlo procedures laid out as Bayesian tests provide more robust correlation coefficients than traditional tests do. It also shows that traditional path statistics are both textually and conceptionally like Bayes theorems, and that structural equations models computed from them are the basis of multistep regressions, as used with causal Bayesian networks.

Understanding Clinical Data Analysis

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Publisher : Springer
ISBN 13 : 3319395866
Total Pages : 241 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Understanding Clinical Data Analysis by : Ton J. Cleophas

Download or read book Understanding Clinical Data Analysis written by Ton J. Cleophas and published by Springer. This book was released on 2016-08-23 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook consists of ten chapters, and is a must-read to all medical and health professionals, who already have basic knowledge of how to analyze their clinical data, but still, wonder, after having done so, why procedures were performed the way they were. The book is also a must-read to those who tend to submerge in the flood of novel statistical methodologies, as communicated in current clinical reports, and scientific meetings. In the past few years, the HOW-SO of current statistical tests has been made much more simple than it was in the past, thanks to the abundance of statistical software programs of an excellent quality. However, the WHY-SO may have been somewhat under-emphasized. For example, why do statistical tests constantly use unfamiliar terms, like probability distributions, hypothesis testing, randomness, normality, scientific rigor, and why are Gaussian curves so hard, and do they make non-mathematicians getting lost all the time? The book will cover the WHY-SOs.

Statistical Analysis of Clinical Data on a Pocket Calculator

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Publisher : Springer Science & Business Media
ISBN 13 : 9400712111
Total Pages : 62 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Statistical Analysis of Clinical Data on a Pocket Calculator by : Ton J. Cleophas

Download or read book Statistical Analysis of Clinical Data on a Pocket Calculator written by Ton J. Cleophas and published by Springer Science & Business Media. This book was released on 2011-04-26 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt: The core principles of statistical analysis are too easily forgotten in today’s world of powerful computers and time-saving algorithms. This step-by-step primer takes researchers who lack the confidence to conduct their own analyses right back to basics, allowing them to scrutinize their own data through a series of rapidly executed reckonings on a simple pocket calculator. A range of easily navigable tutorials facilitate the reader’s assimilation of the techniques, while a separate chapter on next generation Flash prepares them for future developments in the field. This practical volume also contains tips on how to deny hackers access to Flash internet sites. An ideal companion to the author’s co-authored works on statistical analysis for Springer such as Statistics Applied to Clinical Trials, this monograph will help researchers understand the processes involved in interpreting clinical data, as well as being a necessary prerequisite to mastering more advanced statistical techniques. The principles of statistical analysis are easily forgotten in today’s world of time-saving algorithms. This step-by-step primer takes researchers back to basics, enabling them to examine their own data through a series of sums on a simple pocket calculator.

Regression Analysis in Medical Research

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Publisher : Springer Nature
ISBN 13 : 3030613941
Total Pages : 471 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Regression Analysis in Medical Research by : Ton J. Cleophas

Download or read book Regression Analysis in Medical Research written by Ton J. Cleophas and published by Springer Nature. This book was released on 2021-03-01 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regression analysis of cause effect relationships is increasingly the core of medical and health research. This work is a 2nd edition of a 2017 pretty complete textbook and tutorial for students as well as recollection / update bench and help desk for professionals. It came to the authors' attention, that information of history, background, and purposes, of the regression methods addressed were scanty. Lacking information about all of that has now been entirely covered. The editorial art work of the first edition, however pretty, was less appreciated by some readerships, than were the original output sheets from the statistical programs as used. Therefore, the editorial art work has now been systematically replaced with original statistical software tables and graphs for the benefit of an improved usage and understanding of the methods. In the past few years, professionals have been flooded with big data. The Covid-19 pandemic gave cause for statistical software companies to foster novel analytic programs better accounting outliers and skewness. Novel fields of regression analysis adequate for such data, like sparse canonical regressions and quantile regressions, have been included.

Machine Learning in Medicine - a Complete Overview

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Publisher : Springer
ISBN 13 : 3319151959
Total Pages : 498 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Machine Learning in Medicine - a Complete Overview by : Ton J. Cleophas

Download or read book Machine Learning in Medicine - a Complete Overview written by Ton J. Cleophas and published by Springer. This book was released on 2015-03-27 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current book is the first publication of a complete overview of machine learning methodologies for the medical and health sector. It was written as a training companion and as a must-read, not only for physicians and students, but also for any one involved in the process and progress of health and health care. In eighty chapters eighty different machine learning methodologies are reviewed, in combination with data examples for self-assessment. Each chapter can be studied without the need to consult other chapters. The amount of data stored in the world's databases doubles every 20 months, and clinicians, familiar with traditional statistical methods, are at a loss to analyze them. Traditional methods have, indeed, difficulty to identify outliers in large datasets, and to find patterns in big data and data with multiple exposure / outcome variables. In addition, analysis-rules for surveys and questionnaires, which are currently common methods of data collection, are, essentially, missing. Fortunately, the new discipline, machine learning, is able to cover all of these limitations. So far medical professionals have been rather reluctant to use machine learning. Also, in the field of diagnosis making, few doctors may want a computer checking them, are interested in collaboration with a computer or with computer engineers. Adequate health and health care will, however, soon be impossible without proper data supervision from modern machine learning methodologies like cluster models, neural networks and other data mining methodologies. Each chapter starts with purposes and scientific questions. Then, step-by-step analyses, using data examples, are given. Finally, a paragraph with conclusion, and references to the corresponding sites of three introductory textbooks, previously written by the same authors, is given.

Essential Statistics for Medical Practice

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Publisher : CRC Press
ISBN 13 : 1351088807
Total Pages : 184 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Essential Statistics for Medical Practice by : D.G. Rees

Download or read book Essential Statistics for Medical Practice written by D.G. Rees and published by CRC Press. This book was released on 2018-01-18 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: A firm understanding of the basic statistical methods used in current medical literature is now essential for medical practice, as research papers have become increasingly statistical in nature. This book has a unique, case-study approach, starting with six actual research papers showing which statistical methods were used and how the results were obtained. It will enable the medical professional to understand the methods in an easy and accessible way.

Machine Learning in Medicine

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Publisher : Springer Science & Business Media
ISBN 13 : 9400778694
Total Pages : 234 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Machine Learning in Medicine by : Ton J. Cleophas

Download or read book Machine Learning in Medicine written by Ton J. Cleophas and published by Springer Science & Business Media. This book was released on 2013-11-26 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Machine learning is concerned with the analysis of large data and multiple variables. It is also often more sensitive than traditional statistical methods to analyze small data. The first and second volumes reviewed subjects like optimal scaling, neural networks, factor analysis, partial least squares, discriminant analysis, canonical analysis, fuzzy modeling, various clustering models, support vector machines, Bayesian networks, discrete wavelet analysis, association rule learning, anomaly detection, and correspondence analysis. This third volume addresses more advanced methods and includes subjects like evolutionary programming, stochastic methods, complex sampling, optional binning, Newton's methods, decision trees, and other subjects. Both the theoretical bases and the step by step analyses are described for the benefit of non-mathematical readers. Each chapter can be studied without the need to consult other chapters. Traditional statistical tests are, sometimes, priors to machine learning methods, and they are also, sometimes, used as contrast tests. To those wishing to obtain more knowledge of them, we recommend to additionally study (1) Statistics Applied to Clinical Studies 5th Edition 2012, (2) SPSS for Starters Part One and Two 2012, and (3) Statistical Analysis of Clinical Data on a Pocket Calculator Part One and Two 2012, written by the same authors, and edited by Springer, New York.

Sample Size Calculations in Clinical Research

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Publisher : CRC Press
ISBN 13 : 1351727117
Total Pages : 825 pages
Book Rating : 4.3/5 (517 download)

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Book Synopsis Sample Size Calculations in Clinical Research by : Shein-Chung Chow

Download or read book Sample Size Calculations in Clinical Research written by Shein-Chung Chow and published by CRC Press. This book was released on 2017-08-15 with total page 825 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the Second Edition: "... this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study." -Biometrics "This impressive book contains formulae for computing sample size in a wide range of settings. One-sample studies and two-sample comparisons for quantitative, binary, and time-to-event outcomes are covered comprehensively, with separate sample size formulae for testing equality, non-inferiority, and equivalence. Many less familiar topics are also covered ..." – Journal of the Royal Statistical Society Sample Size Calculations in Clinical Research, Third Edition presents statistical procedures for performing sample size calculations during various phases of clinical research and development. A comprehensive and unified presentation of statistical concepts and practical applications, this book includes a well-balanced summary of current and emerging clinical issues, regulatory requirements, and recently developed statistical methodologies for sample size calculation. Features: Compares the relative merits and disadvantages of statistical methods for sample size calculations Explains how the formulae and procedures for sample size calculations can be used in a variety of clinical research and development stages Presents real-world examples from several therapeutic areas, including cardiovascular medicine, the central nervous system, anti-infective medicine, oncology, and women’s health Provides sample size calculations for dose response studies, microarray studies, and Bayesian approaches This new edition is updated throughout, includes many new sections, and five new chapters on emerging topics: two stage seamless adaptive designs, cluster randomized trial design, zero-inflated Poisson distribution, clinical trials with extremely low incidence rates, and clinical trial simulation.

Scientific and Technical Aerospace Reports

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Publisher :
ISBN 13 :
Total Pages : 666 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Scientific and Technical Aerospace Reports by :

Download or read book Scientific and Technical Aerospace Reports written by and published by . This book was released on 1982 with total page 666 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lists citations with abstracts for aerospace related reports obtained from world wide sources and announces documents that have recently been entered into the NASA Scientific and Technical Information Database.