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Sorting And Prohormone Processing Within The Regulated Secretory Pathway Of The Pituitary Derived Att 20 Cell Line
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Book Synopsis Sorting and Prohormone Processing Within the Regulated Secretory Pathway of the Pituitary-derived AtT-20 Cell Line by : Walter Kenneth Schmidt
Download or read book Sorting and Prohormone Processing Within the Regulated Secretory Pathway of the Pituitary-derived AtT-20 Cell Line written by Walter Kenneth Schmidt and published by . This book was released on 1995 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Targeting of Hormones to the Regulated Secretory Pathway in an Anterior Pituitary Cell Line by : Sharon Kay Powell
Download or read book Targeting of Hormones to the Regulated Secretory Pathway in an Anterior Pituitary Cell Line written by Sharon Kay Powell and published by . This book was released on 1988 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Proteolytic and Cellular Mechanisms in Prohormone and Proprotein Processing by : Vivian Yuan-Hen Ho Hook
Download or read book Proteolytic and Cellular Mechanisms in Prohormone and Proprotein Processing written by Vivian Yuan-Hen Ho Hook and published by Landes Bioscience. This book was released on 1998 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Secretory Granule by : Alan M. Poisner
Download or read book The Secretory Granule written by Alan M. Poisner and published by . This book was released on 1982 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cellular Peptide Hormone Synthesis and Secretory Pathways by : Jens F. Rehfeld
Download or read book Cellular Peptide Hormone Synthesis and Secretory Pathways written by Jens F. Rehfeld and published by Springer Science & Business Media. This book was released on 2010-03-10 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of hormonal regulation using intercellular peptide messengers dates back to the discovery of secretin in 1902. The concept was simple: A peptide is released from specific hormone producing cells, endocrine cells, into circulation upon stimulation of the cells. The peptide hormone travels via blood to its target, the cells of which are equipped with specific receptors for high-affinity binding of the particular peptide hormone. Receptor binding subsequently elicits action of the target cells. This concept has been seriously challenged by modern biochemistry and cell biology. Thus, it is now well established that the gene of a specific peptide hormone may be expressed in different types of endocrine cells, in neurons, and in some instances also in adipocytes, myocytes, osteoblasts, and immune cells. Today, only a few hormones – including the old master hormone insulin – represent the original endocrine paradigm. Instead, the widespread cellular synthesis now raises the qu- tion of how the body maintains the regulation of its functions by peptide hormones when a hormone may originate from a variety of cells.
Book Synopsis Physiology of the Gastrointestinal Tract by : Kim E. Barrett
Download or read book Physiology of the Gastrointestinal Tract written by Kim E. Barrett and published by Elsevier. This book was released on 2006-05-10 with total page 2098 pages. Available in PDF, EPUB and Kindle. Book excerpt: FROM THE PREFACE: The original purpose of the First Edition of Physiology of the Gastrointestinal Tract to collect in one set of volumes the most current and comprehensive knowledge in our field was also the driving force for the Fourth Edition. The explosion of information at the cellular level, made possible in part by the continued emergence of powerful molecular and cellular techniques, has resulted in a greater degree of revision than that of any other edition. The first section, now titled "Basic Cell Physiology and Growth of the Gl Tract" contains numerous new chapters on topics such as transcriptional regulation, signaling networks in development, apoptosis, and mechanisms in malignancies. Most of the chapters in this section were edited by Juanita L. Merchant. Section II has been renamed "Neural Gastroenterology and Motility" and has been expanded from seven chapters with rather classic titles to more than twenty chapters encompassing not only the movement of the various parts of the digestive tract but also cell physiology, neural regulation, stress, and the regulation of food intake. Almost all of the chapters were recruited and edited by Jackie D. Wood. The third section is entirely new and contains chapters on "Immunology and Inflammation" which were edited by Kim E. Barrett. The fourth section on the "Physiology of Secretion" consists of chapters with familiar titles, but with completely updated information to reflect the advances in our understanding of the cellular processes involved in secretion. The last section on "Digestion and Absorption" contains new chapters on the intestinal barrier, protein sorting and ion channels along with those focusing on the uptake of specific nutrients. These chapters were recruited and edited by Hamid M. Said and Fayez K. Ghishan. · Collected in one set - the most current and comprehensive coverage of gastrointestinal physiology · Information presented in a style that is both readable and understandable · Valuable to the specialized researcher, the clinical gastroenterologist, the teacher, and the student · Features an entirely new section on Immunology and Inflammation · Each section edited by the preeminent scientist in the field
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2003 with total page 968 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Textbook of Energy Balance, Neuropeptide Hormones, and Neuroendocrine Function by : Eduardo A. Nillni
Download or read book Textbook of Energy Balance, Neuropeptide Hormones, and Neuroendocrine Function written by Eduardo A. Nillni and published by Springer. This book was released on 2018-07-20 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook presents for the first time a comprehensive body of the latest knowledge in the field of neuropeptides and their action on energy balance. It contains a detailed and comprehensive account of the specific hypothalamic peptides in regards to their roles in energy balance, food intake control and co-morbidities, to better understand the patho-physiology of obesity. The textbook includes an examination the history of the evolution of human society from a thin to the obese phenotype and, within that context, how modern society habits and industrial food production did not respect the evolutionary trait resulting in changes in the energy balance set point. It provides a novel conceptualization of the problem of obesity when considering the biochemistry of peptide hormones and entertaining novel ideas on multiple approaches to the problems of energy balance, as well as demonstrates and explains why alterations in pro-hormone processing are paramount to understand metabolic disease. This text is excellent material for teaching graduate and medical school courses, as well as a valuable resource for researchers in biochemistry, cell, and molecular biology, neuroscientists, physician endocrinologists, and nutritionists.
Download or read book Acromegaly written by Richard J. Robbins and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: The manuscripts in this volume were contributed by the speakers invited to the Acromegaly Centennial Symposium held in San Francisco, California in July 1986. The meeting was organized to commemorate the description of acromegaly by the French physician Pierre Marie, in 1886. The members of the Scientific Committee spent many hours assisting us in ensuring an outstanding meeting. The support of Serono Symposia, USA in all phases of the planning and execution of the meeting was sincerely appreciated and was highly professional. Special recognition roust be extended to Professor Roger Guillemin of the Salk Institute, whosp interest in medical history led him to devote a great deal of time and personal expense in obtaining information about the life of Pierre Marie. Dr. GuilIemin's presentation on the life and times of Marie was an extraordinary overview of the cultural, social, and scientific backgrounds in which Marie came to describe the disease, acromegaly. Dr. Guillemin' s findings, which were presented at the main banquet in a splendid audiovisual presentation, were clearly the highlight of the meeting and will long be remembered by the attendees. We were also honored by the presence of Dr. Martine Pierre Marie Granier, the great-granddaughter of Pierre Harie. In her address at the banquet, Dr. Granier provided several delightful and intimate vignettes concerning Pierre Marie, using old family records and photographs. The Scientific Committee wishes to extend its gratitude to Dr. Granier for adding immeasurably to the historical atmosphere of the meeting.
Book Synopsis Handbook of Stress and the Brain Part 1: The Neurobiology of Stress by : Thomas Steckler
Download or read book Handbook of Stress and the Brain Part 1: The Neurobiology of Stress written by Thomas Steckler and published by Elsevier. This book was released on 2005-03-24 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Stress and the Brain focuses on the impact of stressful events on the functioning of the central nervous system; how stress affects molecular and cellular processes in the brain, and in turn, how these brain processes determine our perception of and reactivity to, stressful challenges - acutely and in the long-run. Written for a broad scientific audience, the Handbook comprehensively reviews key principles and facts to provide a clear overview of the interdisciplinary field of stress. The work aims to bring together the disciplines of neurobiology, physiology, immunology, psychology and psychiatry, to provide a reference source for both the non-clinical and clinical expert, as well as serving as an introductory text for novices in this field of scientific inquiry. Part 1 addresses basic aspects of the neurobiology of the stress response including the involvement of neuropeptide, neuroendocrine and neurotransmitter systems and its corollaries regarding gene expression and behavioural processes such as cognition, motivation and emotionality. * Provides an overview of recent advances made in stress research * Includes timely discussion of stress and its effect on the immune system * Presents novel treatment strategies targeting brain processes involved in stress processing and coping mechanisms
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1999 with total page 1846 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Peptidergic Neuron by : B. Krisch
Download or read book The Peptidergic Neuron written by B. Krisch and published by Birkhäuser. This book was released on 2012-12-06 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuropeptides rank among the phylogenetically oldest interneuronal signal substances. In the concept of neuro-secretion they were identified as neurohormones by which - via the blood - the brain regulates peripheral functions. It is now evident that the neuropeptides act as neurotransmitters/-modulators, as (neuro-)hormones, and paracrine or autocrine signal substances in diverse parts of the body. This book reviews, in several comprehensive articles written by distinguished specialists, the state of the art in the field of neuropeptides and peptidergic neurons. Special topics concern molecular aspects of processing, release and degradation of neuropeptides, receptors and signal transduction, comparative and behavioural aspects, and immunoregulatory effects of neuropeptides and their involvement on pathology of the central nervous system.
Book Synopsis Dissertation Abstracts International by :
Download or read book Dissertation Abstracts International written by and published by . This book was released on 1996 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Williams Textbook of Endocrinology E-Book by : Shlomo Melmed
Download or read book Williams Textbook of Endocrinology E-Book written by Shlomo Melmed and published by Elsevier Health Sciences. This book was released on 2011-05-12 with total page 1920 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest edition of Williams Textbook of Endocrinology edited by Drs. Shlomo Melmed, Kenneth S. Polonsky, P. Reed Larsen, and Henry M. Kronenberg, helps you diagnose and treat your patients effectively with up-to-the minute, practical know-how on all endocrine system disorders. Comprehensive yet accessible, this extensively revised 12th Edition updates you on diabetes, metabolic syndrome, obesity, thyroid disease, testicular disorders, and much more so you can provide your patients with the most successful treatments. Find scientific insight and clinical data interwoven in every chapter, reflecting advances in both areas of this constantly changing discipline, and presented in a truly accessible format. You’ll also access valuable contributions from a dynamic list of expert authors and nearly 2.000 full-color images to help you with every diagnosis. This title has everything you need to manage any and all the clinical endocrinopathies you may encounter. Rely on the one reference that integrates rapidly evolving basic and clinical science in a cohesive, user-friendly format, definitively addresses every topic in the field, and has remained a standard for more than half a century. Update your know-how and skills to diagnose and treat your patients most effectively with exhaustively revised content on diabetes, metabolic disease, thyroid cancer, fertility problems, testicular problems, weight issues, and much more. Apply reliable guidance on endocrine conditions of growing interest like hypothyroidism and testicular disorders, with dedicated new chapters that expound on the latest research findings. Overcome any clinical challenge with comprehensive and easy-to-use coverage of everything from hormone activity, diagnostic techniques, imaging modalities, and molecular genetics, to total care of the patient. Apply the latest practices with guidance from expert authors who contribute fresh perspectives on every topic.
Book Synopsis Handbook of Proteolytic Enzymes by : Alan J. Barrett
Download or read book Handbook of Proteolytic Enzymes written by Alan J. Barrett and published by Academic Press. This book was released on 2012-10-30 with total page 4097 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensively revised and updated, the new edition of the highly regarded Handbook of Proteolytic Enzymes is an essential reference for biochemists, biotechnologists and molecular biologists. Edited by world-renowned experts in the field, this comprehensive work provides detailed information on all known proteolytic enzymes to date. This two-volume set unveils new developments on proteolytic enzymes which are being investigatedin pharmaceutical research for such diseases as HIV, Hepatitis C, and the common cold. Volume I covers aspartic and metallo petidases while Volume II examines peptidases of cysteine, serine, threonine and unknown catalytic type. A CD-ROM accompanies the book containing fully searchable text, specialised scissile bond searches, 3-D color structures and much more. The only comprehensive book on proteolytic enzymes Includes 671 chapters, each written by experts in their field, on proteolytic enzymes from all groups of living organisms and the viruses, including those that are currently major targets of pharmaceutical research Accompanying CD-ROM provides fully searchable text, 2D structures of peptidases in color and links directly to PubMed and MEROPS databases Each chapter describes in detail the enzyme name, its history, activity and specificity, structural chemistry, preparation, biological aspects and distinguishing features Over 1000 peptidases included
Book Synopsis Reviews on Biomarker Studies of Metabolic and Metabolism-Related Disorders by : Paul C. Guest
Download or read book Reviews on Biomarker Studies of Metabolic and Metabolism-Related Disorders written by Paul C. Guest and published by Springer. This book was released on 2019-03-27 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book recognizes that throughout the scientific, medical, and economic communities, new tests incorporating biomarkers are needed to improve the diagnosis of patients suffering from metabolic disorders. The early identification of those at risk of developing obesity will help to place these individuals on the best treatment course as early as possible for improved treatment outcomes. This will also help to cut costs incurred by the healthcare services. For all of this to occur, new research efforts are needed to identify novel biomarkers that can be used to predict the disease in the presymptomatic stage, for disease monitoring and for prediction of treatment response. It is also possible that new drug targets can be identified using these approaches which, in turn, can lead to the development of new treatment approaches. This volume also includes a series of reviews on biomarker discovery and usage in the study of diseases marked by perturbations in metabolism. It will describe the pros and cons of the various approaches and cover the successes and failures in this important research field.
Book Synopsis Peptide Biosynthesis and Processing by : Lloyd D. Fricker
Download or read book Peptide Biosynthesis and Processing written by Lloyd D. Fricker and published by CRC Press. This book was released on 1991-07-24 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive review of the field of peptide biosynthesis. Individual chapters range from historical perspectives of the field to current knowledge regarding specific enzymes. Every step from gene to final bioactive peptide is covered in detail. Approximately two thirds of the book reviews the enzymes responsible for intracellular and extracellular peptide processing. Other chapters cover issues such as tissue-specific processing and the subcellular sorting of the peptides. New areas covered include the discovery, purification, characterization, and cDNA cloning of peptide processing enzymes involved with endopeptidase processing, carboxypeptidase processing, and C-terminal amidation; identification of the mammalian KEX-2 (subtilisin-like) family of proteases; identification of a second enzyme involved in C-terminal amidation; and the characterization of regulatory elements in neuropeptide genes and the associated DNA-binding proteins, such as CREB and related proteins, in addition to the Pit-1/GHF-1 family of proteins. The book's extensive coverage and 1000 references make it important reading material for new and established researchers in this rapidly expanding field.
