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Some Aspects Of The Chemistry And Biosynthesis Of Isoquinoline Alkaloids
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Book Synopsis The Chemistry and Biology of Isoquinoline Alkaloids by : J.D. Phillipson
Download or read book The Chemistry and Biology of Isoquinoline Alkaloids written by J.D. Phillipson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Isoquinolines form one of the largest groups of plant alkaloids and they in clude a number of valuable clinical agents such as codeine, morphine, eme tine and tubocurarine. Research into different aspects of isoquinolines con tinues in profusion, attracting the talents of botanists, chemists, bioche mists, analysts, pharmacists and pharmacologists. Many of these aspects are of an interdisciplinary nature, and in April 1984, The Phytochemical Society of Europe arranged a 3-day symposium on The Chemistry and Bi ology of Isoquinoline Alkaloids in order to provide a forum for scientists of differing disciplines who are united by a common interest in this one class of natural product. Each chapter in this volume is based on a lecture given at this symposium. Attempts have been made to make the aims and objectives, experimental findings and conclusions reached, intelligible to scientists of differing backgrounds. The introductory chapter, which is mainly based on a historical discus sion, stresses that plants containing isoquinolines have proved to be both a boon and a curse to mankind. The Opium Poppy, Papaver somniferum, produces the medicinally used alkaloids morphine, codeine, noscapine and papaverine whilst it also continues to provide drugs of abuse, particularly morphine and its readily prepared O,O-diacetyl derivative, heroin. Numer ous other alkaloids have been isolated from other members of the Papaver acea, and a knowledge of their presence and distribution within the various species has proved a useful adjunct to systematic botanical studies.
Book Synopsis The Isoquinoline Alkaloids by : K. W. Bentley
Download or read book The Isoquinoline Alkaloids written by K. W. Bentley and published by Elsevier. This book was released on 2014-04-24 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Isoquinoline Alkaloids: A Course in Organic Chemistry is a description of the chemical structures of alkaloids. The book discusses the processes for degradation of isoquinoline alkaloids to recognizable compounds such as oxidation and exhaustive methylation. The associated processes in removing the nitrogen atom are also explained. The commonly used Hofmann process and the interpretation of its result are evaluated in the degradation of alkaloids. The cactus ""pellote"" used by Mexican Indians to induce hallucinatory experiences is examined. The active ingredient is identified as mescaline; its composition is analyzed to contain one primary amino and three methoxyl groups. The different syntheses made to duplicate mescaline are described. The structures of morphine, codeine, and thebain, which are all alkaloids of opium, are also analyzed. Another example of a principal alkaloid found in a plant is emetine found in the root of the ipecac. The pharmacological bases of emetine are isolated and noted as emetamine, cephaeline, psychotrine, and O-methylpsychotrine. The text also traces many other structural relationships within the subgroups of the isoquinoline alkaloids. Chemists, students and professors in organic chemistry, and laboratory technicians whose work is related to pharmacology will find this book informative.
Book Synopsis The Isoquinoline Alkaloids Chemistry and Pharmacology by : Maurice Shamma
Download or read book The Isoquinoline Alkaloids Chemistry and Pharmacology written by Maurice Shamma and published by Elsevier. This book was released on 2012-12-02 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Isoquinoline Alkaloids: Chemistry and Pharmacology presents an overview of the chemistry, biogenesis, spectroscopy, and pharmacology of the isoquinoline alkaloids. This book examines the significant and interesting aspects of alkaloids. Organized into 32 chapters, this book starts with a discussion of the biogenesis of the isoquinolines and the various pharmacological effects of simple tetrahydroisoquinolines that have stimulant and convulsive properties. This text then explores the infrared absorptions, with emphasis on wavelength and frequency. Other chapters include topics on synthesis, degradation, reactions, absolute configuration, as well as on ultraviolet and nuclear magnetic resonance spectroscopy. This book further explores the various methods available for the preparation of simple tetrahydroisoquinolines, including the Bischler–Napieralski, Pictet–Spengler, and phenolic cyclization, as well as the Friedel–Crafts acylation. The last chapter deals with ancistrocladine, which is the first isoquinoline alkaloid found to possess a methyl group. Biochemists and biophysicists will find this book useful.
Book Synopsis The Biochemistry of Alkaloids by : Trevor Robinson
Download or read book The Biochemistry of Alkaloids written by Trevor Robinson and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: The alkaloids were of great importance to mankind for centuries, long before they were recognized as a chemical class. The influence they have had on literature is hinted at by some of the quotations I have used as chapter headings. Their in fluence on folklore and on medicine has been even greater. The scientific study of alkaloids may be said to have begun with the isolation of morphine by SERTURNER in 1804. Since that time they have remained of great interest to chemists, and now in any month there appear dozens of publications dealing with the isolation of new alkaloids or the determination of the structures of previously known ones. The area of alkaloid biochemistry, in comparison, has received little attention, and today is much less developed. There is a certain amount of personal arbitrariness in defining "biochemistry", as there is in defining "alkaloid", and this arbitrariness is doubtless compounded by the combination. Nevertheless, it seems to me that in any consideration of the bio chemistry of a group of compounds three aspects are always worthy of attention pathways of biosynthesis, function or activity, and pathways of degradation. For the alkaloids, treatment of these three aspects is necessarily lopsided. Much has been learned about routes of biosynthesis, but information on the other aspects is very scanty. It would be possible to enter into some speculation regarding the biosyn thesis of all the more than 1,000 known alkaloids.
Author :Hans-Joachim Knoelker Publisher :Springer Science & Business Media ISBN 13 :3642255280 Total Pages :268 pages Book Rating :4.6/5 (422 download)
Book Synopsis Alkaloid Synthesis by : Hans-Joachim Knoelker
Download or read book Alkaloid Synthesis written by Hans-Joachim Knoelker and published by Springer Science & Business Media. This book was released on 2012-01-13 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lycopodium Alkaloids: Isolation and Asymmetric Synthesis, by Mariko Kitajima and Hiromitsu Takayama.- Synthesis of Morphine Alkaloids and Derivatives, by Uwe Rinner and Tomas Hudlicky.- Indole Prenylation in Alkaloid Synthesis, by Thomas Lindel, Nils Marsch and Santosh Kumar Adla.- Marine Pyrroloiminoquinone Alkaloids, by Yasuyuki Kita and Hiromichi Fujioka.- Synthetic Studies on Amaryllidaceae and Other Terrestrially Derived Alkaloids, by Martin G. Banwell, Nadia Yuqian Gao, Brett D. Schwartz and Lorenzo V. White.- Synthesis of Pyrrole and Carbazole Alkaloids, by Ingmar Bauer and Hans-Joachim Knölker.-
Book Synopsis Ranunculales Medicinal Plants by : Da-Cheng Hao
Download or read book Ranunculales Medicinal Plants written by Da-Cheng Hao and published by Academic Press. This book was released on 2018-04-23 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ranunculales Medicinal Plants: Biodiversity, Chemodiversity and Pharmacotherapy comprehensively covers this order of flowering plants, detailing the phytochemistry, chemotaxonomy, molecular biology, and phylogeny of selected medicinal plants families and genera and their relevance to drug efficacy. The book carries out an exhaustive survey of the literature in order to characterize global trends in the application of flexible technologies. The interrelationship between Chinese species, and between Chinese and non-Chinese species, is inferred through molecular phylogeny and based on nuclear and chloroplast DNA sequencing. The book discusses the conflict between chemotaxonomy and molecular phylogeny in the context of drug discovery and development. Users will find invaluable and holistic coverage on the study of Ranunculales that will make this the go-to pharmaceutical resource. - Describes current perceptions of biodiversity and chemodiversity of Ranunculales - Explains how the conceptual framework of plant pharmacophylogeny benefits the sustainable exploitation of Ranunculales - Details how Ranunculales medicinal plants work from the chemical level upward - Covers how the polypharmacology of Ranunculales compounds might inspire new chemical entity design and development for improved treatment outcomes
Book Synopsis Alkaloids - Secrets of Life: by : Tadeusz Aniszewski
Download or read book Alkaloids - Secrets of Life: written by Tadeusz Aniszewski and published by Elsevier. This book was released on 2007-03-22 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alkaloids, represent a group of interesting and complex chemical compounds, produced by the secondary metabolism of living organisms in different biotopes. They are relatively common chemicals in all kingdoms of living organisms in all environments. Two hundred years of scientific research has still not fully explained the connections between alkaloids and life.Alkaloids-Chemistry, Biological Significance, Applications and Ecological Role provides knowledge on structural typology, biosynthesis and metabolism in relation to recent research work on alkaloids. Considering an organic chemistry approach to alkaloids using biological and ecological explanation. Within the book several questions that persist in this field of research are approached as are some unresearched areas. The book provides beneficial text for an academic and professional audience and serves as a source of knowledge for anyone who is interested in the fascinating subject of alkaloids. Each chapter features an abstract. Appendices are included, as are a listing of alkaloids, plants containing alkaloids and some basic protocols of alkaloid analysis.* Presents the ecological role of alkaloids in nature and ecosystems * Interdisciplinary and reader friendly approach* Up-to-date knowledge
Book Synopsis Biodiversity and Chemotaxonomy by : Kishan Gopal Ramawat
Download or read book Biodiversity and Chemotaxonomy written by Kishan Gopal Ramawat and published by Springer Nature. This book was released on 2019-11-10 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant classifications are based on morphological characters and it is difficult, particularly in small plants and grasses, to identify these below generic level on the basis of these characters using a dissecting microscope. Plant species have intra- and inter-specific variation in secondary metabolites which can be utilized as marker compounds for identification and classification of plants. Secondary metabolites are produced as a result of primary metabolism and the production of these compounds not only involves several genes but also it is an energy dependent process. Hence these products cannot be considered as insignificant for the plant and the environment. Modern tools of molecular biology and secondary metabolites present in them can definitively decide about classification of plants. Absence of correct identification of plant is associated to many problems of resource utilization. Due to wide availability of these tools, interest has revived in systematics and correct classification of plants based on these parameters for their sustainable utilization and resource management. The purpose of this book is to assess the potential of phytochemical and molecular tools in the systematic and classification of plants. The topics covered include species concept, barcoding and phylogenetic analysis, chemotaxonomy use of polyketides, carotenes, cuticular wax, volatile oils, biodiversity of corals, metazoans, Ruta and Echinocereus. It provides comprehensive and broad subject-based reviews, useful for students, teachers, researchers, and all others interested in the field. The field has been kept wide and general to accommodate the wide-ranging topics. This book will be useful to agriculturists, chemists, botanists, industrialists, and those involved in planning of crop plants.
Book Synopsis Recent Advances in Natural Products Analysis by : Seyed Mohammad Nabavi
Download or read book Recent Advances in Natural Products Analysis written by Seyed Mohammad Nabavi and published by Elsevier. This book was released on 2020-03-07 with total page 880 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Advances in Natural Products Analysis is a thorough guide to the latest analytical methods used for identifying and studying bioactive phytochemicals and other natural products. Chemical compounds, such as flavonoids, alkaloids, carotenoids and saponins are examined, highlighting the many techniques for studying their properties. Each chapter is devoted to a compound category, beginning with the underlying chemical properties of the main components followed by techniques of extraction, purification and fractionation, and then techniques of identification and quantification. Biological activities, possible interactions, levels found in plants, the effects of processing, and current and potential industrial applications are also included. - Focuses on the latest analytical techniques used for studying phytochemical and other biological compounds - Authored and edited by the top worldwide experts in their field - Discusses the current and potential applications and predicts future trends of each compound group
Book Synopsis Natural Product Biosynthesis by : Christopher T. Walsh
Download or read book Natural Product Biosynthesis written by Christopher T. Walsh and published by Royal Society of Chemistry. This book was released on 2017-04-28 with total page 787 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook describes the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era.
Book Synopsis Biochemistry and Molecular Biology of Plants by : Bob B. Buchanan
Download or read book Biochemistry and Molecular Biology of Plants written by Bob B. Buchanan and published by John Wiley & Sons. This book was released on 2015-08-31 with total page 1280 pages. Available in PDF, EPUB and Kindle. Book excerpt: With over 1000 original drawings and 500 photographs, this work offers complete coverage of cell biology, plant physiology and molecular biology.
Download or read book Alkaloids written by Margaret F. Roberts and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Not since the late 1970s has a single work presented the biology of this heterogenous group of secondary alkaloids in such depth. Alkaloids, a unique treatise featuring leaders in the field, presents both the historical use of alkaloids and the latest discoveries in the biochemistry of alkaloid production in plants alkaloid ecology, including marine invertebrates, animal and plant parasites, and alkaloids as antimicrobial and current medicinal use . Highlights include chapters on the chemical ecology of alkaloids in host-predator interactions, and on the compartmentation of alkaloids synthesis, transport, and storage. Extensive cross-referencing in tabular format makes this volume an excellent reference.
Book Synopsis Chemistry of Natural Products by : N. R. Krishnaswamy
Download or read book Chemistry of Natural Products written by N. R. Krishnaswamy and published by Universities Press. This book was released on 1999 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive account of the essential features of the chemistry of organic compounds of natural origin. The objective has been to condense the encyclopedic range of the subject into a medium-sized book by taking a radically different approach.
Download or read book Alkaloids written by S. William Pelletier and published by . This book was released on 1983 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Bioactive Natural Products by : Goutam Brahmachari
Download or read book Bioactive Natural Products written by Goutam Brahmachari and published by John Wiley & Sons. This book was released on 2015-03-23 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ein multidisziplinärer Überblick über die aktuellen Themen und Zukunftstrends in der Erforschung von Naturstoffen mit Schwerpunkt auf pharmazeutischen und medizinischen Anwendungen.
Book Synopsis Lead Compounds from Medicinal Plants for the Treatment of Neurodegenerative Diseases by : Christophe Wiart
Download or read book Lead Compounds from Medicinal Plants for the Treatment of Neurodegenerative Diseases written by Christophe Wiart and published by Academic Press. This book was released on 2013-12-16 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lead Compounds from Medicinal Plants for the Treatment of Neurodegenerative Diseases is the second volume in the series, Pharmaceutical Leads from Medicinal Plants. This book includes key pharmacological and chemical evidence to support the selection of promising pre-clinical candidates for the treatment of neurodegenerative diseases. This important addition to the natural product and drug discovery literature contains the history, synonyms, medicinal uses, phytopharmacology, pre-clinical potential, and rationale for each plant selected. By providing critical evaluation of pharmacological data, mechanisms of action, and structural requirements for the development of future neuroprotective agents, this comprehensive reference is a beneficial resource for industry and academic scientists whose research focuses on neurodegenerative drug discovery and development. - Incorporates compelling biological activity data and preclinical structure-activity relationships to help you choose promising lead molecules for further research - Includes primary source references to the most recent natural product discoveries in the field of neuroprotection in order to promote new drug discovery in this area - Contains detailed discussions of important neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease - Each plant section includes a critical evaluation of pharmacological, chemical, and toxicological evidence to support the use of the compound in drug discovery research in neurodegeneration
Book Synopsis Plant Natural Products by : Herwig O. Gutzeit
Download or read book Plant Natural Products written by Herwig O. Gutzeit and published by John Wiley & Sons. This book was released on 2014-05-05 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Im Gegensatz zu existierenden Fachbüchern, die sich entweder ausschließlich auf die pharmakologischen Eigenschaften von pflanzlichen Naturstoffen konzentrieren oder den Sekundärstoffwechsel von Pflanzen im Rahmen der allgemeinen Pflanzenwissenschaft behandeln, deckt dieses Lehrbuch sämtliche Aspekte in einem Band ab. Es überzeugt durch Modernität, enthält farbige Abbildungen, einen Fragen- und Antwortteil und bietet Zugang zu einer begleitenden Website. Darüber hinaus liefern die einleitenden Kapitel ausreichend Hintergrundinformationen zur Chemie und Biochemie pflanzlicher Naturstoffe und deren Einsatz in der Biotechnologie. Damit ist dieses Lehrbuch in jeder Hinsicht als eigenständiges Werk in entsprechenden Kursen einsetzbar.
