Author : Vijay Agarwal
Publisher : LAP Lambert Academic Publishing
ISBN 13 : 9783848405985
Total Pages : 112 pages
Book Rating : 4.4/5 (59 download)
Book Synopsis Solid Dosage Form of Senna Leaves Powder and Their Extract by : Vijay Agarwal
Download or read book Solid Dosage Form of Senna Leaves Powder and Their Extract written by Vijay Agarwal and published by LAP Lambert Academic Publishing. This book was released on 2014-03 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most of herbal formulations have lacking of preformulational and post formulational studies. Thus, an attempt was made to performed the preformulation and post formulation characteristics for senna leaf powder and calcium sennoside. The conventional tablet of senna leaf powder and calcium sennoside may release a significant amount of drug in the physiological environment of stomach before reaching at the site of action. Hence, enteric coated tablet of calcium sennoside and senna leaf powder was prepared using cellulose acetate phthalate for averting the initial loss of 5-8% sennoside in stomach. For this purpose different formulational factors were optimized. The in-vitro release of coated tablet was performed in 0.1 N Hcl and phosphate buffer of pH 6.8. After the enteric coating, the tablet ensured that it was more pH dependent and release the drug only at higher pH. This research work should be especially useful to professionals engaged in formulation development of herbal drugs, or anyone else who wants to perform the preformulation and post formulation study of herbal drugs.