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Author : Society for Biomolecular Screening
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (821 download)
Download or read book Society for Biomolecular Screening written by Society for Biomolecular Screening and published by . This book was released on 2001 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Society for Biomolecular Screening
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (796 download)
Download or read book Society for Biomolecular Screening written by Society for Biomolecular Screening and published by . This book was released on 1997 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Society for Biomolecular Screening
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (596 download)
Download or read book The First Annual Conference of the Society for Biomolecular Screening written by Society for Biomolecular Screening and published by . This book was released on 1995 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Society for Biomolecular Screening
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (595 download)
Download or read book The Fourth Annual Conference of the Society for Biomolecular Screening written by Society for Biomolecular Screening and published by . This book was released on 1998 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Society for Biomolecular Screening
Publisher :
ISBN 13 :
Total Pages : 192 pages
Book Rating : 4.:/5 (5 download)
Download or read book The Society for Biomolecular Screening written by Society for Biomolecular Screening and published by . This book was released on 1999 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : D. Lansing Taylor
Publisher : Springer Science & Business Media
ISBN 13 : 1597452173
Total Pages : 437 pages
Book Rating : 4.5/5 (974 download)
Download or read book High Content Screening written by D. Lansing Taylor and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has always been some tension between proponents of hypothesis-driven and discovery-driven research in the broad field of life sciences. Academic research has been primarily focused on hypothesis-driven research. However, the success of the human genome project, a discovery-driven research approach, has opened the door to adding other types of discovery-driven research to a continuum of research approaches. In contrast, drug discovery research in the pharmaceutical industry has embraced discovery-driven research for many years. A good example has been the discovery of active compounds from large chemical libraries, through screening campaigns. The success of the human genome project has also demonstrated the need for both academic researchers and industrial researchers to now understand the functions of genes and gene products. The cell is the basic unit of life and it has been at the cellular level where function can be demonstrated most cost-effectively and rapidly. High content screening (HCS) was developed by Cellomics Inc. in the mid-1990s to address the need for a platform that could be used in the discovery-driven research and development required to understand the functions of genes and gene products at the level of the cell.
Author : William P. Janzen
Publisher : Springer Science & Business Media
ISBN 13 : 1592591809
Total Pages : 269 pages
Book Rating : 4.5/5 (925 download)
Download or read book High Throughput Screening written by William P. Janzen and published by Springer Science & Business Media. This book was released on 2008-02-05 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: In High Throughput Screening, leading scientists and researchers expert in molecular discovery explain the diverse technologies and key techniques used in HTS and demonstrate how they can be applied generically. Writing to create precisely the introductory guidebook they wish had been available when they started in HTS, these expert seasoned authors illuminate the HTS process with richly detailed tutorials on the biological techniques involved, the management of compound libraries, and the automation and engineering approaches needed. Extensive discussions provide readers with all those key elements of pharmacology, molecular biology, enzymology, and biochemistry that will ensure the identification of suitable targets and screens, and detail the technology necessary to mine millions of data points for meaningful knowledge.
Author : Steven A. Haney
Publisher : John Wiley & Sons
ISBN 13 : 0470624566
Total Pages : 348 pages
Book Rating : 4.4/5 (76 download)
Download or read book An Introduction To High Content Screening written by Steven A. Haney and published by John Wiley & Sons. This book was released on 2015-01-07 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using a collaborative and interdisciplinary author base with experience in the pharmaceutical industry and academia, this book is a practical resource for high content (HC) techniques. • Instructs readers on the fundamentals of high content screening (HCS) techniques • Focuses on practical and widely-used techniques like image processing and multiparametric assays • Breaks down HCS into individual modules for training and connects them at the end • Includes a tutorial chapter that works through sample HCS assays, glossary, and detailed appendices
Author : Alan L. Harvey
Publisher : CRC Press
ISBN 13 : 9780471975090
Total Pages : 232 pages
Book Rating : 4.9/5 (75 download)
Download or read book Advances in Drug Discovery Techniques written by Alan L. Harvey and published by CRC Press. This book was released on 1998-08-15 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to techniques for the discovery and evaluation of pharamcologically active compounds for therapeutic development, this book covers rational drug design, high-throughput screening, and genetic approaches to drug discovery. The authors focus on advances in the use of combinatorial chemistry and natural products, both of which support the chemical diversity for many drug screening programmes. They examine typical screening studies and their link to robotics and informatics in detail and present an overview of current progress within anitsense therapeutics. The book explores the rapid changes in drug discovery resulting from developments in molecular biology, robotics, and informatics.
Author : Ramakrishna Seethala
Publisher : CRC Press
ISBN 13 : 0824741447
Total Pages : 619 pages
Book Rating : 4.8/5 (247 download)
Download or read book Handbook of Drug Screening written by Ramakrishna Seethala and published by CRC Press. This book was released on 2001-07-24 with total page 619 pages. Available in PDF, EPUB and Kindle. Book excerpt: A presentation of screening techniques, modern technologies, and high-capacity instrumentation for increased productivity in the development and discovery of new drugs, chemical compounds, and targeted delivery of pharmaceuticals. It contains practical applications and examples of strategies in cell-based and cell-free screens as well as homogeneous, fluorescence, chemiluminescence, and radioactive-based technologies.
Author : Donald C. Lo
Publisher : CRC Press
ISBN 13 : 1420008250
Total Pages : 342 pages
Book Rating : 4.4/5 (2 download)
Download or read book Neurobiology of Huntington's Disease written by Donald C. Lo and published by CRC Press. This book was released on 2010-07-02 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1993, the genetic mutation responsible for Huntington's disease (HD) was identified. Considered a milestone in human genomics, this discovery has led to nearly two decades of remarkable progress that has greatly increased our knowledge of HD, and documented an unexpectedly large and diverse range of biochemical and genetic perturbations that see
Author : K. V. Peter
Publisher : Elsevier
ISBN 13 : 185573835X
Total Pages : 375 pages
Book Rating : 4.8/5 (557 download)
Download or read book Handbook of Herbs and Spices written by K. V. Peter and published by Elsevier. This book was released on 2004-03-23 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Together with its companion volume, Handbook of herbs and spices: Volume 2 provides a comprehensive and authoritative coverage of key herbs and spices. Chapters on individual plants cover such issues as description and classification, production, chemical structure and properties, potential health benefits, uses in food processing and quality issues. Authoritative coverage of more than 50 major herbs and spices Provides detailed information on chemical structure, cultivation and definition Incorporates safety issues, production, main uses, health issues and regulations
Author : Shayne Cox Gad
Publisher : John Wiley & Sons
ISBN 13 : 1118077113
Total Pages : 1943 pages
Book Rating : 4.1/5 (18 download)
Download or read book Development of Therapeutic Agents Handbook written by Shayne Cox Gad and published by John Wiley & Sons. This book was released on 2011-10-24 with total page 1943 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive look at current drug discovery and development methods—and the roadmap for the future Providing both understanding and guidance in characterizing potential drugs and their production and synthesis, Development of Therapeutic Agents Handbook gives professionals a basic tool to facilitate research and development within this challenging process. This comprehensive text brings together, in one resource, a compendium of concepts, approaches, methodologies, and limitations that need to be considered in the formulation of therapeutic agents across a range of therapeutic fields. Both a reference and a call to action for the pharmaceutical industry, Development of Therapeutic Agents Handbook examines recent innovations taking shape in the various medical disciplines involved in drug discovery, and shows why these advances need to be embraced universally among researchers to improve their solution strategies. Additional subject matter includes: Extensive coverage and in-depth look into novel treatments and therapeutics Discussion of hot topics like new drugs and nutraceuticals, the discovery and development of vaccines, cancer therapeutics, and market overviews Coverage of therapeutic drug development for specific disease areas, such as cardiology, oncology, breast cancer, and kidney diseases As research in biology, chemistry, medicine, and technology rapidly progresses, it is becoming increasingly important for medical researchers to maintain an up-to-date knowledge base of emerging trends directing promising new therapies. Development of Therapeutic Agents Handbook serves this purpose, acting as both a one-stop reference rich in valid science, and a tool to carve out new pathways in the pursuit of bringing safer and more effective drugs to the marketplace.
Author : Kerstin Thurow
Publisher : John Wiley & Sons
ISBN 13 : 3527348328
Total Pages : 516 pages
Book Rating : 4.5/5 (273 download)
Download or read book Devices and Systems for Laboratory Automation written by Kerstin Thurow and published by John Wiley & Sons. This book was released on 2022-08-08 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: Devices and Systems for Laboratory Automation Structured Overview on the Available Systems and Devices for Laboratory Automation Choosing the right systems and devices for the automation in any given laboratory is an essential part for the process to succeed. As relevant information to make an informed choice is not always readily available, a structured overview is essential for modern scientists. This book provides an introduction into laboratory automation and an overview of the necessary devices and systems. Sample topics discussed by the two well-qualified authors include: Specific requirements the automation needs to fulfill such as liquid delivery, low volume delivery, solid delivery, and sample preparation An overview on robots and mobile robots Common interfaces in laboratory automation For scientists and all individuals working in laboratories, the work serves as an indispensable resource in helping to make laboratory processes more streamlined, effective, and efficient.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309102936
Total Pages : 64 pages
Book Rating : 4.3/5 (91 download)
Download or read book Path to Effective Recovering of DNA from Formalin-Fixed Biological Samples in Natural History Collections written by National Research Council and published by National Academies Press. This book was released on 2006-10-26 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: Museums catalogue our knowledge of the Earth's biodiversity, and their collections represent many decades of work by experts. Access to DNA sequence information in archival specimens would greatly extend knowledge of the genetic relationships within our biosphere. However, molecular genetic analysis of museum specimens has been slowed by the usual practice of fixation and storage of samples in formalin. Formalin is an environmental toxin and induces genetic and chromosomal alterations to the samples. Few of the many attempts to obtain and sequence DNA from formalin-fixed specimens stored in aqueous formalin or ethanol have been successful. All of the protocols are slow, difficult, and often expensive, and few produce DNA fragments longer than 500 base pairs. Path to Effective Recovering of DNA from Formalin-Fixed Biological Samples in Natural History Collections examines past attempts on DNA recovery from formalin-preserved biological specimens and discusses the research needed to advance the development of similar but more efficient and cost-effective protocols.
Author : Kris Gevaert
Publisher : Springer Nature
ISBN 13 : 1071634577
Total Pages : 337 pages
Book Rating : 4.0/5 (716 download)
Download or read book Mass Spectrometry-Based Proteomics written by Kris Gevaert and published by Springer Nature. This book was released on 2023-09-04 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume explores contemporary techniques in mass spectrometry-based proteomics. After covering overall proteome coverage and the cellular surfaceome, the book delves into proximity-induced biotinylation, abduction of protein complexes in viral-like particles, and thermal proteome profiling, as well as protocols for identifying protein N-terminal acetylation, protein processing by proteases, protein N-glycosylation, and protein phosphorylation. The book also collects chapters on automated preparation of clinical samples, the analysis of formalin-fixed paraffin-embedded samples, protocols for the isolation of extracellular vesicles and for the monitoring of selected protein modifications in clinical samples, and, finally, structural proteomics. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Mass Spectrometry-Based Proteomics serves as an ideal guide to its subject for both novices in the field of proteomics as well as specialists.
Author : Naomi E. Chayen
Publisher : Internat'l University Line
ISBN 13 : 9780972077439
Total Pages : 300 pages
Book Rating : 4.0/5 (774 download)
Download or read book Protein Crystallization Strategies for Structural Genomics written by Naomi E. Chayen and published by Internat'l University Line. This book was released on 2007 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt:
