Single Molecule Studies Of Kinesin Mechanochemistry

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Single Molecule Biology

Author : Alexander E. Knight
Publisher : Academic Press
ISBN 13 : 008092123X
Total Pages : 369 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Single Molecule Biology by : Alexander E. Knight

Download or read book Single Molecule Biology written by Alexander E. Knight and published by Academic Press. This book was released on 2009-02-26 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Single molecule techniques, including single molecule fluorescence, optical tweezers, and scanning probe microscopy, allow for the manipulation and measurement of single biological molecules within a live cell or in culture. These approaches, amongst the most exciting tools available in biology today, offer powerful new ways to elucidate biological function, both in terms of revealing mechanisms of action on a molecular level as well as tracking the behaviour of molecules in living cells. This book provides the first complete and authoritative treatment of this rapidly emerging field, explicitly from a biological perspective.The contents are organized by biological system or molecule. Each chapter discusses insights that have been revealed about their mechanism, structure or function by single molecule techniques. Among the topics covered are enzymes, motor proteins, membrane channels, DNA, ribozymes, cytoskeletal proteins, and other key molecules of current interest. An introduction by the editor provides a concise review of key principles and an historical overview. The last section discusses applications in molecular diagnostics and drug discovery. - Organized by biological system or molecule - Each chapter discusses insights into mechanism of action, structure, and function - Covers enzymes, motor proteins, membrane channels, DNA, ribozymes, etc - Includes an introduction to key principles and an historical overview - Discusses applications in molecular diagnostics and drug discovery - Provides an expert's perspective on future development

Single-molecule Studies of Proteins

Author : Andres F. Oberhauser
Publisher : Springer Science & Business Media
ISBN 13 : 1461449219
Total Pages : 283 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Single-molecule Studies of Proteins by : Andres F. Oberhauser

Download or read book Single-molecule Studies of Proteins written by Andres F. Oberhauser and published by Springer Science & Business Media. This book was released on 2012-11-09 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Single Molecule Studies of Proteins, expert researchers discuss the successful application of single-molecule techniques to a wide range of biological events, such as the imaging and mapping of cell surface receptors, the analysis of the unfolding and folding pathways of single proteins, the analysis interaction forces between biomolecules, the study of enzyme catalysis or the visualization of molecular motors in action. The chapters are aimed at established investigators and post-doctoral researchers in the life sciences wanting to pursue research in the various areas in which single-molecule approaches are important; this volume also remains accessible to advanced graduate students seeking similar research goals.

Molecular Biology of the Cell

Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Driving Forces

Author : Ken Dill
Publisher : Garland Science
ISBN 13 : 1136672990
Total Pages : 784 pages
Book Rating : 4.1/5 (366 download)

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Book Synopsis Molecular Driving Forces by : Ken Dill

Download or read book Molecular Driving Forces written by Ken Dill and published by Garland Science. This book was released on 2010-10-21 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Driving Forces, Second Edition E-book is an introductory statistical thermodynamics text that describes the principles and forces that drive chemical and biological processes. It demonstrates how the complex behaviors of molecules can result from a few simple physical processes, and how simple models provide surprisingly accurate insights into the workings of the molecular world. Widely adopted in its First Edition, Molecular Driving Forces is regarded by teachers and students as an accessible textbook that illuminates underlying principles and concepts. The Second Edition includes two brand new chapters: (1) "Microscopic Dynamics" introduces single molecule experiments; and (2) "Molecular Machines" considers how nanoscale machines and engines work. "The Logic of Thermodynamics" has been expanded to its own chapter and now covers heat, work, processes, pathways, and cycles. New practical applications, examples, and end-of-chapter questions are integrated throughout the revised and updated text, exploring topics in biology, environmental and energy science, and nanotechnology. Written in a clear and reader-friendly style, the book provides an excellent introduction to the subject for novices while remaining a valuable resource for experts.

Polymer Mechanochemistry

Author : Roman Boulatov
Publisher : Springer
ISBN 13 : 3319228250
Total Pages : 443 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Polymer Mechanochemistry by : Roman Boulatov

Download or read book Polymer Mechanochemistry written by Roman Boulatov and published by Springer. This book was released on 2015-10-17 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field. Review articles for the individual volumes are invited by the volume editors. Readership: research chemists at universities or in industry, graduate students.

Deciphering Kinesin Motility with Single Molecule Studies

Author : Kurt S. Thorn
Publisher :
ISBN 13 :
Total Pages : 370 pages
Book Rating : 4.:/5 (82 download)

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Book Synopsis Deciphering Kinesin Motility with Single Molecule Studies by : Kurt S. Thorn

Download or read book Deciphering Kinesin Motility with Single Molecule Studies written by Kurt S. Thorn and published by . This book was released on 2001 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Dyneins

Author : Stephen M. King
Publisher : Academic Press
ISBN 13 : 0128097019
Total Pages : 530 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Dyneins by : Stephen M. King

Download or read book Dyneins written by Stephen M. King and published by Academic Press. This book was released on 2017-11-28 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dyneins: Structure, Biology and Disease, Second Edition, offers a broad view of dyneins mechanics, dysfunction, and disease, providing an overview of dyneins from structure and function, to dysfunction and disease. Since the first edition, enormous strides have been taken in understanding dynein structure, its organization in the axoneme, single molecule motor mechanics, and the consequences of defects for human biology, disease, and development. To account for these enormous strides, the second edition is extensively revised. Additionally, the coverage has expanded from 24 to 42 chapters, and is now housed in two volumes. Much of the expanded coverage occurs in Volume 2 which focuses on dynein dysfunction and disease, such as the role of dynein and cancer. Volume 1 covers the history and evolution of dyneins, dyneins in ciliary biology, and cytoplasmic dynein biology, while Volume 2 covers the structure and mechanics of dynein motors and dynein dysfunction and disease. - Presents a broad-based and up-to date view of dynein mechanics, dysfunction, and disease - Contains approaches from genetics, molecular biology, biochemistry, and biophysics discussed - Provides companion website with movies of dynamic cell behavior - Includes extensive chapters written by leading, global experts

Handbook of Single-Molecule Biophysics

Author : Peter Hinterdorfer
Publisher : Springer Science & Business Media
ISBN 13 : 0387764976
Total Pages : 634 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Handbook of Single-Molecule Biophysics by : Peter Hinterdorfer

Download or read book Handbook of Single-Molecule Biophysics written by Peter Hinterdorfer and published by Springer Science & Business Media. This book was released on 2009-12-24 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook describes experimental techniques to monitor and manipulate individual biomolecules, including fluorescence detection, atomic force microscopy, and optical and magnetic trapping. It includes single-molecule studies of physical properties of biomolecules such as folding, polymer physics of protein and DNA, enzymology and biochemistry, single molecules in the membrane, and single-molecule techniques in living cells.

Single Molecule Chemistry and Physics

Author : Chen Wang
Publisher : Springer Science & Business Media
ISBN 13 : 3540395024
Total Pages : 306 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Single Molecule Chemistry and Physics by : Chen Wang

Download or read book Single Molecule Chemistry and Physics written by Chen Wang and published by Springer Science & Business Media. This book was released on 2006-09-22 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Single-molecule studies constitute a distinguishable category of focused - search in nanoscience and nanotechnology. This book is dedicated to the - troduction of recent advances on single-molecule studies. It will be illustrated that studying single molecules is both intellectually and technologically ch- lenging, and also o?ers vast potential in opening up new scienti?c frontiers. We wish to present the readers with several di?erent techniques for studying single molecules, such as electron-tunneling methods, interaction-force m- surement techniques, optical spectroscopy, plus a number of directions where further progress could be pursued. We hope the work may assist the readers, especially graduate students and those who wish to explore single molecules, to become familiarized with the pace of the progress in this ?eld and the relevant primary techniques. Due to limitation of space, we are not able to elaborate on the technical details of all of the experimental methods that are vital in single molecule studies, so introductions to only selected experimental methods are touched in the context. Since the technical details and theoretical analysis of these techniqueshavealreadybeenthoroughlycoveredinmanyliteratures,weonly provide introductions to the basic principles of the detection techniques here, and focus on their experimental achievements in the area of single-molecule studies. These techniques have proven to be highly e?ective when indep- dently used. The combinationof those techniques could lead to further - vances in the detection capabilities.

Biophysical Chemistry

Author : Dagmar Klostermeier
Publisher : CRC Press
ISBN 13 : 1482252244
Total Pages : 770 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Biophysical Chemistry by : Dagmar Klostermeier

Download or read book Biophysical Chemistry written by Dagmar Klostermeier and published by CRC Press. This book was released on 2018-01-02 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biophysical Chemistry explores the concepts of physical chemistry and molecular structure that underlie biochemical processes. Ideally suited for undergradate students and scientists with backgrounds in physics, chemistry or biology, it is also equally accessible to students and scientists in related fields as the book concisely describes the fundamental aspects of biophysical chemistry, and puts them into a biochemical context. The book is organized in four parts, covering thermodynamics, kinetics, molecular structure and stability, and biophysical methods. Cross-references within and between these parts emphasize common themes and highlight recurrent principles. End of chapter problems illustrate the main points explored and their relevance for biochemistry, enabling students to apply their knowledge and to transfer it to laboratory projects. Features: Connects principles of physical chemistry to biochemistry Emphasizes the role of organic reactions as tools for modification and manipulation of biomolecules Includes a comprehensive section on the theory of modern biophysical methods and their applications

Proteins

Author : David M. Leitner
Publisher : CRC Press
ISBN 13 : 1420087045
Total Pages : 450 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Proteins by : David M. Leitner

Download or read book Proteins written by David M. Leitner and published by CRC Press. This book was released on 2009-09-28 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational modeling can provide a wealth of insight into how energy flow in proteins mediates protein function. Computational methods can also address fundamental questions related to molecular signaling and energy flow in proteins. Proteins: Energy, Heat and Signal Flow presents state-of-the-art computational strategies for studying energy redi

Molecular Motors

Author : Manfred Schliwa
Publisher : John Wiley & Sons
ISBN 13 : 3527605657
Total Pages : 604 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Molecular Motors by : Manfred Schliwa

Download or read book Molecular Motors written by Manfred Schliwa and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest knowledge on molecular motors is vital for the understanding of a wide range of biological and medical topics: cell motility, organelle movement, virus transport, developmental asymmetry, myopathies, and sensory defects are all related to the function or malfunction of these minute molecular machines. Since there is a vast amount of information on motor mechanisms and potential biomedical and nanobiotechnological applications, this handbook fulfills the need for a collection of current research results on the functionality, regulation, and interactions of cytoskeletal, DNA, and rotary motors. Here, leading experts present a concise insight, ranging from atomic structure, biochemistry, and biophysics to cell biology, developmental biology and pathology. Basic principles and applications make this book a valuable reference tool for researchers, professionals, and clinicians alike - all set to become a "classic" in the years to come.

Theory And Evaluation Of Single-molecule Signals

Author : Eli Barkai
Publisher : World Scientific
ISBN 13 : 9814471631
Total Pages : 416 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Theory And Evaluation Of Single-molecule Signals by : Eli Barkai

Download or read book Theory And Evaluation Of Single-molecule Signals written by Eli Barkai and published by World Scientific. This book was released on 2008-10-24 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews recently developed theoretical and numerical approaches to deal with optical and mechanical signals from individual molecules. The character of data generated by single molecules, and more generally by single nano-objects, qualitatively differs from those obtained in conventional experiments on large ensembles of molecules. Fluctuations, randomness and irreproducibility are central to single-molecule measurements, and the specific methods required to extract reliable and statistically relevant information from them are presented here. With contributions mainly from participants of the “Theory, Modeling and Evaluation of Single-Molecule Measurements” workshop held in Leiden, the Netherlands, on April 16-20, 2007, this book is an authoritative compendium on the subject.

Comprehensive Biophysics

Author :
Publisher : Academic Press
ISBN 13 : 0080957188
Total Pages : 3533 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Comprehensive Biophysics by :

Download or read book Comprehensive Biophysics written by and published by Academic Press. This book was released on 2012-04-12 with total page 3533 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biophysics is a rapidly-evolving interdisciplinary science that applies theories and methods of the physical sciences to questions of biology. Biophysics encompasses many disciplines, including physics, chemistry, mathematics, biology, biochemistry, medicine, pharmacology, physiology, and neuroscience, and it is essential that scientists working in these varied fields are able to understand each other's research. Comprehensive Biophysics, Nine Volume Set will help bridge that communication gap. Written by a team of researchers at the forefront of their respective fields, under the guidance of Chief Editor Edward Egelman, Comprehensive Biophysics, Nine Volume Set provides definitive introductions to a broad array of topics, uniting different areas of biophysics research - from the physical techniques for studying macromolecular structure to protein folding, muscle and molecular motors, cell biophysics, bioenergetics and more. The result is this comprehensive scientific resource - a valuable tool both for helping researchers come to grips quickly with material from related biophysics fields outside their areas of expertise, and for reinforcing their existing knowledge. Biophysical research today encompasses many areas of biology. These studies do not necessarily share a unique identifying factor. This work unites the different areas of research and allows users, regardless of their background, to navigate through the most essential concepts with ease, saving them time and vastly improving their understanding The field of biophysics counts several journals that are directly and indirectly concerned with the field. There is no reference work that encompasses the entire field and unites the different areas of research through deep foundational reviews. Comprehensive Biophysics fills this vacuum, being a definitive work on biophysics. It will help users apply context to the diverse journal literature offering, and aid them in identifying areas for further research Chief Editor Edward Egelman (E-I-C, Biophysical Journal) has assembled an impressive, world-class team of Volume Editors and Contributing Authors. Each chapter has been painstakingly reviewed and checked for consistent high quality. The result is an authoritative overview which ties the literature together and provides the user with a reliable background information and citation resource

Single-molecule Studies of DNA Twist Mechanics and Gyrase Mechanochemistry

Author : Jeffrey Chen Gore
Publisher :
ISBN 13 :
Total Pages : 328 pages
Book Rating : 4.:/5 (35 download)

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Book Synopsis Single-molecule Studies of DNA Twist Mechanics and Gyrase Mechanochemistry by : Jeffrey Chen Gore

Download or read book Single-molecule Studies of DNA Twist Mechanics and Gyrase Mechanochemistry written by Jeffrey Chen Gore and published by . This book was released on 2005 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mechanics of Motor Proteins and the Cytoskeleton

Author : Jonathon Howard
Publisher : Sinauer
ISBN 13 : 9780878933334
Total Pages : 0 pages
Book Rating : 4.9/5 (333 download)

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Book Synopsis Mechanics of Motor Proteins and the Cytoskeleton by : Jonathon Howard

Download or read book Mechanics of Motor Proteins and the Cytoskeleton written by Jonathon Howard and published by Sinauer. This book was released on 2005-12-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanics of Motor Proteins and the Cytoskeleton provides a physical foundation for molecular mechanics. Part I explains how small particles like proteins respond to mechanical, thermal, and chemical forces, Part II focuses on cytoskeletal filaments, and Part III focuses on motor proteins. The treatments are unified in the respect that they are organized around principles rather than proteins: chapters are centred on topics such as structure, chemistry, and mechanics, and different filaments or motors are discussed together.

Motor Proteins and Molecular Motors

Author : Anatoly B. Kolomeisky
Publisher : CRC Press
ISBN 13 : 1482224763
Total Pages : 221 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Motor Proteins and Molecular Motors by : Anatoly B. Kolomeisky

Download or read book Motor Proteins and Molecular Motors written by Anatoly B. Kolomeisky and published by CRC Press. This book was released on 2015-05-21 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Unified Microscopic Approach to Analyzing Complex Processes in Molecular MotorsMotor Proteins and Molecular Motors explores the mechanisms of cellular functioning associated with several specific enzymatic molecules called motor proteins. Motor proteins, also known as molecular motors, play important roles in living systems by supporting cellular