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Sialobiology Structure Biosynthesis And Function Sialic Acid Glycoconjugates In Health And Disease
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Download or read book Sialobiology written by Joe Tiralongo and published by . This book was released on 2013-02-13 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "This ebook presents a summary of central aspects of sialobiology (i.e., the study of sialic acid and its relevance to biology). The importance of substitution by the sugar sialic acid and the role played by sialylated structures (eg. glycoproteins, glycol"
Book Synopsis Sialobiology: Structure, Biosynthesis and Function. Sialic Acid Glycoconjugates in Health and Disease by : Joe Tiralongo
Download or read book Sialobiology: Structure, Biosynthesis and Function. Sialic Acid Glycoconjugates in Health and Disease written by Joe Tiralongo and published by Bentham Science Publishers. This book was released on 2013-02-13 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: This ebook presents a summary of central aspects of sialobiology (i.e., the study of sialic acid and its relevance to biology). The importance of substitution by the sugar sialic acid and the role played by sialylated structures (eg. glycoproteins, glycolipids, glycoconjugates) in immune recognition, neural cell growth, embryogenesis and disease development including microbial pathogenesis and cancer progression, has become well-established. Since 1995, the field of sialobiology has expanded greatly as many of the key enzymes involved in sialic acid biosynthesis, as well as the vast majority of sialic acid binding lectins involved in immune recognition, have only been cloned, characterised and structural eluciated after the publication of earlier works on the subject. This e-book also covers these recent developments. Chapters in this e-book have been contributed by eminent sialobiologists. Therefore, a book of this nature is timely and will prove to be a definitive volume with a high impact in this field for glycobiologists and cell biologists.
Book Synopsis Essentials of Glycobiology by : Ajit Varki
Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Book Synopsis Sialic Acids, Part I: Historical Background and Development and Chemical Synthesis by :
Download or read book Sialic Acids, Part I: Historical Background and Development and Chemical Synthesis written by and published by Academic Press. This book was released on 2018-11-30 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sialic Acids, Volume 75, a recent release in the Advances in Carbohydrate Chemistry and Biochemistry series, is the first volume of a two-volume set devoted to the sialic acids. Vol. 75 includes a broad-based historical overview of the field by two pioneers in the identification, structural development, and chemistry and biochemistry of the sialic acids. A second chapter is devoted to the finer aspects of the modern, up-to-date chemical synthesis of the all-important glycosides of N-acetylneuraminic acid, a class of sialic acid derivatives with a myriad of functions. Features contributions from leading authorities and industry experts who specialize in carbohydrate chemistry, biochemistry and research Integrates the industrial, analytical and technological aspects of biochemistry, organic chemistry and instrumentation methodology in the study of carbohydrates Informs and updates on all the latest developments in the field
Book Synopsis Handbook of Carbohydrate-Modifying Biocatalysts by : Peter Grunwald
Download or read book Handbook of Carbohydrate-Modifying Biocatalysts written by Peter Grunwald and published by CRC Press. This book was released on 2016-11-25 with total page 1056 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an actual overview of the structure, function, and application of carbohydrate-modifying biocatalysts. Carbohydrates have been disregarded for a long time by the scientific community, mainly due to their complex structure. Meanwhile, the situation changed with increasing knowledge about the key role carbohydrates play in biological processes such as recognition, signal transduction, immune responses, and others. An outcome of research activities in glycoscience is the development of several new pharmaceuticals against serious diseases such as malaria, cancer, and various storage diseases. Furthermore, the employment of carbohydrate-modifying biocatalysts—enzymes as well as microorganisms—will contribute significantly to the development of environmentally friendly processes boosting a shift of the chemical industry from petroleum- to bio-based production of chemicals from renewable resources. The updated content of the second edition of this book has been extended by discussing the current state of the art of using recombinantly expressed carbohydrate-modifying biocatalysts and the synthesis of minicellulosomes in connection with consolidated bioprocessing of lignocellulosic material. Furthermore, a synthetic biology approach for using DAHP-dependent aldolases to catalyze asymmetric aldol reactions is presented.
Book Synopsis Glycobiology and Human Diseases by : Gherman Wiederschain
Download or read book Glycobiology and Human Diseases written by Gherman Wiederschain and published by CRC Press. This book was released on 2016-02-22 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses glycobiology and various forms of human diseases. Topics covered include immunoglobulins, inflammation and glycosylation, the role and therapeutic significance of natural anti-glycan antibodies in malignancies and in normal and aberrant pregnancy, identifying urinary glycans as a possible method for the diagnosis of lysosomal st
Book Synopsis Advances in Chromatography by : Nelu Grinberg
Download or read book Advances in Chromatography written by Nelu Grinberg and published by CRC Press. This book was released on 2024-08-20 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: For six decades, scientists and researchers have relied on the Advances in Chromatography series for the most up-to-date information on a wide range of developments in chromatographic methods and applications. The clear presentation of topics and vivid illustrations for which this series has become known make the material accessible and engaging to analytical, biochemical, organic, polymer, and pharmaceutical chemists at all levels of technical skill. Presents an in-depth review of chaotropic chromatography. Reviews recent advances in HPLC and SFC columns packed with hybrid organic/inorganic particles. Explores new advances in nano-liquid chromatography for proteomics analysis. Outlines the heterogeneity of gangliosides and advances in the chromatographic techniques used in their separation.
Book Synopsis Foodborne Pathogens by : Joshua B. Gurtler
Download or read book Foodborne Pathogens written by Joshua B. Gurtler and published by Springer. This book was released on 2017-06-14 with total page 653 pages. Available in PDF, EPUB and Kindle. Book excerpt: Foodborne illnesses continue to be a major public health concern. All members of a particular bacterial genera (e.g., Salmonella, Campylobacter) or species (e.g., Listeria monocytogenes, Cronobacter sakazakii) are often treated by public health and regulatory agencies as being equally pathogenic; however, this is not necessarily true and is an overly conservative approach to ensuring the safety of foods. Even within species, virulence factors vary to the point that some isolates may be highly virulent, whereas others may rarely, if ever, cause disease in humans. Hence, many food safety scientists have concluded that a more appropriate characterization of bacterial isolates for public health purposes could be by virotyping, i.e., typing food-associated bacteria on the basis of their virulence factors. The book is divided into two sections. Section I, “Foodborne Pathogens and Virulence Factors,” hones in on specific virulence factors of foodborne pathogens and the role they play in regulatory requirements, recalls, and foodborne illness. The oft-held paradigm that all pathogenic strains are equally virulent is untrue. Thus, we will examine variability in virulence between strains such as Listeria, Salmonella, Campylobacter, Cronobacter, etc. This section also examines known factors capable of inducing greater virulence in foodborne pathogens. Section II, “Foodborne Pathogens, Host Susceptibility, and Infectious Dose” , covers the ability of a pathogen to invade a human host based on numerous extraneous factors relative to the host and the environment. Some of these factors include host age, immune status, genetic makeup, infectious dose, food composition and probiotics. Readers of this book will come away with a better understanding of foodborne bacterial pathogen virulence factors and pathogenicity, and host factors that predict the severity of disease in humans.
Book Synopsis Biology of the Sialic Acids by : A. Rosenberg
Download or read book Biology of the Sialic Acids written by A. Rosenberg and published by Springer Science & Business Media. This book was released on 1995-07-31 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abraham Rosenberg assembles the groundbreaking work of preeminent international scientists to provide the most current, state-of-the-art presentation of research in siabiology. This concise volume examines the historical development of the field and reviews current knowledge on the genetic, immunologic, oncologic, neurodevelopmental, pathogenic, and cell regulatory properties of sialic acid. Outstanding features of this work include exhaustive reference material and detailed information tables.
Book Synopsis Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease by : Roger N. Rosenberg
Download or read book Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease written by Roger N. Rosenberg and published by Elsevier. This book was released on 2014-10-28 with total page 1465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Fifth Edition provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to the majority of neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling. Every chapter has been thoroughly revised or newly commissioned to reflect the latest scientific and medical advances by an international team of leading scientists and clinicians. The contents have been expanded to include disorders for which a genetic basis has been recently identified, together with abundant original illustrations that convey and clarify the key points of the text in an attractive, didactic format. Previous editions have established this book as the leading tutorial reference on neurogenetics. Researchers will find great value in the coverage of genomics, animal models and diagnostic methods along with a better understanding of the clinical implications. Clinicians will rely on the coverage of the basic science of neurogenetics and the methods for evaluating patients with biochemical abnormalities or gene mutations, including links to genetic testing for specific diseases. Comprehensive coverage of the neurogenetic foundation of neurological and psychiatric disease Detailed introduction to both clinical and basic research implications of molecular and genetic understanding of the brain Detailed coverage of genomics, animal models and diagnostic methods with new coverage of evaluating patients with biochemical abnormalities or gene mutations
Book Synopsis Alcohol and Its Biomarkers by : Amitava Dasgupta
Download or read book Alcohol and Its Biomarkers written by Amitava Dasgupta and published by Elsevier. This book was released on 2015-02-18 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol and Its Biomarkers: Clinical Aspects and Laboratory Determination is a concise guide to all currently known alcohol biomarkers, their clinical application, and the laboratory methods used to detect them. Pathologists can use this resource to understand the limitations and cost factors associated with each method for determining certain alcohol biomarkers. In addition, interferences in these determinations are discussed, so that clinicians can understand the causes of falsely elevated biomarkers and pathologists and laboratory scientists can potentially eliminate them. The book focuses on the analytical methods used to detect alcohol in blood and urine, the limitations of alcohol determination using enzymatic methods, and the differences between clinical and forensic alcohol measurement. Chapters also cover cutting-edge alcohol biomarkers for potential use. - Focuses on the analytical methods used for detecting alcohol in blood and urine along with the pitfalls and limitations of alcohol determination using enzymatic methods - Explains the difference between clinical and forensic alcohol measurement - Includes a brief overview of the benefits of consuming alcohol in moderation and the hazards of heavy drinking
Book Synopsis Sialic Acids, Part II: Biological and Biomedical Aspects by : David C. Baker
Download or read book Sialic Acids, Part II: Biological and Biomedical Aspects written by David C. Baker and published by Academic Press. This book was released on 2019-03-07 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sialic Acids, Volume 76, the most recent release in the Advances in Carbohydrate Chemistry and Biochemistry series, is the second volume of a two-volume set devoted to the sialic acids. Vol. 76, devoted to the biological and biomedical aspects of sialic acids, includes chapters on "Sialic Acids in Neurology," "Sialic Acids in Nonenveloped Virus Infections," and "The Biology of Gangliosides," all written by leading experts in their fields. Features contributions from leading authorities and industry experts who specialize in carbohydrate chemistry, biochemistry and research Integrates the industrial, analytical and technological aspects of biochemistry, organic chemistry and instrumentation methodology in the study of carbohydrates Informs and updates on all the latest developments in the field
Book Synopsis Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease by : Shyamasree Ghosh
Download or read book Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease written by Shyamasree Ghosh and published by Academic Press. This book was released on 2020-01-08 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease enables the reader to understand the role of sialylation as a post translational modification. The book provides insights on the latest knowledge in the field of sialoglycobiology. Sialic acids as terminal residues of oligosaccharide chains play crucial roles in several cellular recognition events. Synthesized post translationally, they play an important role in recognition, signaling, immunological response and cell-cell interaction. Improper sialylations have been associated with several diseases including cancer. In the post genomics and proteomics era, sialoglybiology has become more and more important in deciphering health and disease conditions. Discusses the sialic acids and their role in different diseases (other than cancer) Provides an understanding of sialylations as post translational modifications (PTM) Demonstrates the impact sialylation has on infectious diseases, the autoimmune system and health Gives insights on the importance of sialic acid biology through animal models
Book Synopsis Liposome Methods and Protocols by : Subhash C. Basu
Download or read book Liposome Methods and Protocols written by Subhash C. Basu and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: In vitro utilization of liposomes is now recognized as a powerful tool in many bioscience investigations and their associated clinical studies, e.g., liposomes in drug targeting; liposomes in gene transport across plasma and nuclear membranes; liposomes in enzyme therapy in patients with genetic disorders. However, before these areas can be effectively explored, many basic areas in liposome research require elucidation, including: (a) attachment of liposomes to cell surfaces; (b) permeation of liposomes through the plasma membranes; and (c) stability of liposomes in cell or nuclear matrices. None of these areas have been exhaustively explored and liposome researchers have ample opportunities to contribute to our knowledge. The aim of Liposome Methods and Protocols is to bring together a wide range of detailed laboratory protocols covering different aspects of liposome biology in order to assist researchers in those rapidly advancing medical fields mentioned earlier. With this goal in mind, in each protocol chapter we have detailed the materials to be used, followed by a step-by-step protocol. The Notes section of each protocol is also certain to prove particularly useful, since the authors include troubleshooting tips straight from their benchtops, valuable information that is seldom given in restricted methods sections of standard research journals. For this reason we feel that the book will prove especially useful for all researchers in the liposome field.
Book Synopsis Adenoviral Vectors for Gene Therapy by : David T. Curiel
Download or read book Adenoviral Vectors for Gene Therapy written by David T. Curiel and published by Academic Press. This book was released on 2016-03-10 with total page 870 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adenoviral Vectors for Gene Therapy, Second Edition provides detailed, comprehensive coverage of the gene delivery vehicles that are based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, making gene therapy a fast-growing field for research. This book presents topics ranging from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models, with final consideration of the regulatory issues surrounding human clinical gene therapy trials. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors. Provides complete coverage of the basic biology of adenoviruses, as well as their construction, propagation, and purification of adenoviral vectors Introduces common strategies for the development of adenoviral vectors, along with cutting-edge methods for their improvement Demonstrates noninvasive imaging of adenovirus-mediated gene transfer Discusses utility of adenoviral vectors in animal disease models Considers Federal Drug Administration regulations for human clinical trials
Download or read book Glycosylation and Cancer written by and published by Academic Press. This book was released on 2015-02-26 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics. Provides information on cancer research Outstanding and original reviews Suitable for researchers and students
Book Synopsis The Molecular Immunology of Complex Carbohydrates-3 by : Albert M. Wu
Download or read book The Molecular Immunology of Complex Carbohydrates-3 written by Albert M. Wu and published by Springer Science & Business Media. This book was released on 2011-05-27 with total page 823 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the third symposium on “Molecular Immunology of Complex Carbohydrates,” this text covers the latest in glycotopes, structures and functions of complex carbohydrates, recognition factors of lectins, biomolecular interactions and other glycosciences. This volume highlights the informative events of the Symposium on Molecular Immunology of Complex Carbohydrates III, held at the Institute of Biological Chemistry, Academia Sinica, on July 15-20, 2007, in Taipei, Taiwan.
