Sex Steroids and Apoptosis In Skeletal Muscle: Molecular Mechanisms

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Publisher : Bentham Science Publishers
ISBN 13 : 9811412359
Total Pages : 191 pages
Book Rating : 4.8/5 (114 download)

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Book Synopsis Sex Steroids and Apoptosis In Skeletal Muscle: Molecular Mechanisms by : Andrea A. Vasconsuelo

Download or read book Sex Steroids and Apoptosis In Skeletal Muscle: Molecular Mechanisms written by Andrea A. Vasconsuelo and published by Bentham Science Publishers. This book was released on 2019-06-03 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph focuses on the actions exerted by sex hormones, 17β-estradiol and testosterone, in skeletal muscle tissue. An important consideration of this volume is the fact that both estrogen receptors (ERs) and androgen receptors (ARs) are ubiquitously expressed and, as a result, steroid hormones affect growth and different cell functions in several organs. Moreover, ERs and ARs may have a non-classical pattern of intracellular localizations, raising complexity to the functional roles of estradiol and testosterone. Readers will find key information about the role of sex hormones in mitochondrial physiology and their relation with ageing, apoptosis, and sarcopenia. Chapters integrate important points with the latest information on the subject, including work of leading researchers studying the cellular and molecular mechanisms underlying the age-linked changes in muscle tissue while highlighting the role of satellite cells. Furthermore, the book presents a chapter about phytoestrogens (compounds which are structurally very similar to estrogen 17β-estradiol) and their selective action on sex steroid receptors (specifically, they have a higher affinity for ERβ receptors than ERα receptors). The book is recommended reading for scientists and clinicians involved in the field of medical and health sciences as well as for scholarly readers (students of biochemistry and medicine) who are interested in the molecular mechanism of cellular apoptosis regulated by steroid hormones.

Advanced Exercise Endocrinology

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Publisher : Human Kinetics
ISBN 13 : 073607516X
Total Pages : 274 pages
Book Rating : 4.7/5 (36 download)

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Book Synopsis Advanced Exercise Endocrinology by : Katarina T. Borer

Download or read book Advanced Exercise Endocrinology written by Katarina T. Borer and published by Human Kinetics. This book was released on 2013 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Exercise Endocrinology provides a comprehensive examination of the relationship between physical activity and hormone function. It is an essential reference for exercise physiologists and physiotherapists researching the connections between exercise, hormone function, and health.

Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity

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Publisher : Springer
ISBN 13 : 3319701789
Total Pages : 627 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity by : Franck Mauvais-Jarvis

Download or read book Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity written by Franck Mauvais-Jarvis and published by Springer. This book was released on 2017-12-08 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on “Sex and gender factors affecting metabolic homeostasis, diabetes and obesity” to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases. There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence both the development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men.

Integrative Biology of Women’s Health

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Publisher : Springer Science & Business Media
ISBN 13 : 1461486300
Total Pages : 217 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Integrative Biology of Women’s Health by : Espen E. Spangenburg

Download or read book Integrative Biology of Women’s Health written by Espen E. Spangenburg and published by Springer Science & Business Media. This book was released on 2013-10-24 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Defining and understanding cellular and molecular mechanisms that are relevant to women’s health has become a critical area of scientific pursuit. Until recently, very little effort has been place on defining or understanding critical differences between women and men that may be critical to the overall health of the woman. In 1990, the National Institutes of Health recognized this gap in knowledge resulting in the creation of the Office of Research on Women’s Health. One of the purposes of this office was to advance the understanding of health issues from the women’s perspective from both a basic and clinical scientific perspective. From a scientific evolution of understanding, the existence of this office is new and thus there has not been enough time for new information to integrate itself in our current scientific thought process. This book will seek to capture and disseminate our current understanding of scientific advancements relevant to women’s health and provide the information to a broad audience. The purpose of this work is to discuss recent advancements in basic science across three areas of concern for women’s health. In addition, the book will provide “translational” chapters that attempt to place the basic science work in context within our current understanding of the human. Although it is well acknowledge that gender differences exist across organ function which translates into differences in whole body function, until recently little effort has been made to define basic mechanisms within various tissues within the woman. This work will focus on recent scientific findings that are relevant to women’s health and to provide novel and relevant information to interested scientists and clinicians.

CiteSpace

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Publisher : Nova Science Publishers
ISBN 13 : 9781536102802
Total Pages : 0 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis CiteSpace by : Chaomei Chen

Download or read book CiteSpace written by Chaomei Chen and published by Nova Science Publishers. This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: CiteSpace is a freely available computer program written in Java for visualizing and analyzing literature of a scientific domain. A knowledge domain is broadly defined in order to capture the notion of a logically and cohesively organized body of knowledge. It may range from specific topics such as post-traumatic stress disorder to fields of study lacking clear-cut boundaries, such as research on terrorism or regenerative medicine. CiteSpace takes bibliographic information, especially citation information from the Web of Science, and generates interactive visualizations. Users can explore various patterns and trends uncovered from scientific publications, and develop a good understanding of scientific literature much more efficiently than they would from an unguided search through literature. The full text of many scientific publications can be accessed with a single click through the interactive visualization in CiteSpace. At the end of a session, CiteSpace can generate a summary report to summarize key information about the literature analyzed. This book is a practical guide not only on how to operate the tool but also on why the tool is designed and what implications of various patterns that require special attention. This book is written with a minimum amount of jargon. It uses everyday language to explain what people may learn from the writings of scholars of all kinds.

Mechanisms of Insulin Action

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Publisher : Springer Science & Business Media
ISBN 13 : 0387722041
Total Pages : 223 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Mechanisms of Insulin Action by : Alan R. Saltiel

Download or read book Mechanisms of Insulin Action written by Alan R. Saltiel and published by Springer Science & Business Media. This book was released on 2007-10-05 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. This book attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. It explores insulin action at the most basic levels, through complex systems.

Sports Endocrinology

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318058696
Total Pages : 172 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Sports Endocrinology by : F. Lanfranco

Download or read book Sports Endocrinology written by F. Lanfranco and published by Karger Medical and Scientific Publishers. This book was released on 2016-06-28 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an up-to-date, extensive overview of the effects of physical activity and training on endocrine function. It gives insights into a complex relationship by describing effects with respect to exercise performance, growth, development, and ageing. It includes discussions of the endocrine response depending on exercise mode, intensity, and duration as well as on gender, age, and fitness level. Additionally the book deals with the impact of environmental and psychological factors on endocrine level. A substantial part of Sports Endocrinology is devoted to the 'hot topic' of hormonal doping in sports. The properties of androgens, growth hormone, erythropoietin, and dietary supplements are highlighted. The use and abuse among professional and recreational athletes is discussed and specific methods of detection are presented and explained. All contributors are well-known experts in sports medicine and endocrinology, endocrine physiology, pharmacology, and doping detection, so this book is a must-read for every professional involved in the field.

Hormonal Pathology of the Uterus

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Publisher : Springer Nature
ISBN 13 : 3030384748
Total Pages : 190 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Hormonal Pathology of the Uterus by : Liane Deligdisch-Schor

Download or read book Hormonal Pathology of the Uterus written by Liane Deligdisch-Schor and published by Springer Nature. This book was released on 2020-05-13 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormonal influences, both natural and iatrogenic, are implicated in the most frequent health issues of women. Endometrial cancer is now the most common gynecologic cancer in the United States and the industrialized world. This cancer is strongly related to hormonal and metabolic factors. In addition, breast cancer treated with hormone therapy (Tamoxifen) may, in some cases, be associated with uterine pathology. Hormone therapy is used to improve the physiological effects and counteract abnormal and deleterious effects of “natural” hormonal activity. Millions of women receive hormone therapy at some point of their life: using oral contraceptives, reproductive technology, treatment for post-menopausal symptoms, among other uses. This book addresses a range of women’s health issues, from fertility to neoplasms, and their relationship with natural and iatrogenic hormonal effects. Chapters include clinical and pathological descriptions, theoretical and practical medical issues, and original studies and cases. Controversial issues in certain hormone therapies are presented with updated concepts based on clinical studies and novel statistical methods. The book will be useful for specialized and general physicians, oncologists, endocrinologists, researchers, medical students, and others in the field of women’s health.

Pathophysiology E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323316077
Total Pages : 1866 pages
Book Rating : 4.3/5 (233 download)

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Book Synopsis Pathophysiology E-Book by : Kathryn L. McCance

Download or read book Pathophysiology E-Book written by Kathryn L. McCance and published by Elsevier Health Sciences. This book was released on 2014-01-30 with total page 1866 pages. Available in PDF, EPUB and Kindle. Book excerpt: Well-known for its authoritative and comprehensive coverage, complete treatment of pediatric pathophysiology, and the most extensive illustration program in its field, this textbook features expert content on everything from the general principles of pathophysiology to detailed discussions of genetics and specific diseases. Chapters on alteration present the pathophysiology, clinical manifestations, and evaluation and treatment of each disease to help you learn to identify normal anatomy and physiology, as well as alterations of function in adults and in children. Unparalleled coverage of disease processes makes this text the most comprehensive pathophysiology text available. The largest full-color art program in the field illustrates the clinical manifestations of diseases and disease processes Consistent presentations of each disease with pathophysiology, clinical manifestations, and evaluation and treatment help you find the information you need quickly and easily. Ten separate pediatric chapters cover the pathophysiologic effects on children. Aging content is highlighted throughout the text. An Introduction to Pathophysiology section at the beginning of the text provides a solid start to the basics of the study of disease. Algorithms and flowcharts of diseases and disorders illustrate the disease process in an easy-to-understand format. Nutrition and Disease boxes present evidence-based information on the relationship between health promotion through diet and disease. Updated content on leukocytes in pain modulation, seizure disorders, brain injuries and disorders, acute encephalopathies, reproductive disorders, and much more keep you at the cutting edge of this constantly changing field. What’s New? boxes highlight the most current research and findings to ensure you have the most up-to-date information. New animations, review questions, Key Points, and an audio glossary have been added to the Evolve companion website to strengthen your understanding of key concepts. Media Resources Lists encourage you to develop a study plan to master the important content in each chapter.

Pathogenic Mechanisms in Cardiac and Skeletal Muscle Diseases

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889717267
Total Pages : 191 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Pathogenic Mechanisms in Cardiac and Skeletal Muscle Diseases by : Marcella Canton

Download or read book Pathogenic Mechanisms in Cardiac and Skeletal Muscle Diseases written by Marcella Canton and published by Frontiers Media SA. This book was released on 2021-11-30 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Tissue-Specific Cell Signaling

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Publisher : Springer Nature
ISBN 13 : 3030444368
Total Pages : 444 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Tissue-Specific Cell Signaling by : Joana Vieira Silva

Download or read book Tissue-Specific Cell Signaling written by Joana Vieira Silva and published by Springer Nature. This book was released on 2020-05-29 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Signal transduction comprises the intracellular biochemical signals which induce the appropriate cell response to an external stimulus. The players in signal transduction are diverse, from small molecules as first messengers, to proteins, receptors, transcription factors, among many others. The different signaling pathways and the crosstalk between them originates the unique signaling profile of every cell type in the human body. The cell signaling specificity depends on several aspects including protein composition, subcellular localization and complexes and gene promoters. This textbook provides a comprehensive overview of the specific signaling pathways on a variety of human tissues. This information can be of great value for health science researchers, professionals and students to understand key pathways for tissue-specific functions in the plethora of signals, signals receptors, transducers and effectors. Chapter 3 and 15 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

New Insights into Estrogen/Estrogen Receptor Effects in the Cardiac and Skeletal Muscle

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Publisher : Frontiers Media SA
ISBN 13 : 2889637077
Total Pages : 160 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis New Insights into Estrogen/Estrogen Receptor Effects in the Cardiac and Skeletal Muscle by : Georgios Kararigas

Download or read book New Insights into Estrogen/Estrogen Receptor Effects in the Cardiac and Skeletal Muscle written by Georgios Kararigas and published by Frontiers Media SA. This book was released on 2020-05-06 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cardiovascular Hormone Systems

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Publisher : John Wiley & Sons
ISBN 13 : 3527319204
Total Pages : 459 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Cardiovascular Hormone Systems by : Michael Bader

Download or read book Cardiovascular Hormone Systems written by Michael Bader and published by John Wiley & Sons. This book was released on 2008-10-20 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by a renowned scientist in the field with more than 200 high profile scientific publications to his name, this is the first book to provide a comprehensive overview of all cardiovascular hormone systems. Clearly structured, the text covers steroid and peptide hormones, amines, and arachidonic acid metabolites, as well as such others as nucleotides, nitric oxide, and acetylcholine. An essential reference for researchers working on the cardiovascular system and related diseases.

Disorders of Voluntary Muscle

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Publisher : Cambridge University Press
ISBN 13 : 9780521650625
Total Pages : 800 pages
Book Rating : 4.6/5 (56 download)

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Book Synopsis Disorders of Voluntary Muscle by : George Karpati

Download or read book Disorders of Voluntary Muscle written by George Karpati and published by Cambridge University Press. This book was released on 2001-07-12 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rewritten and redesigned, this remains the one essential text on the diseases of skeletal muscle.

Hormones, Neurotransmitters, and T-Cell Development in Health and Disease

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Publisher : Frontiers Media SA
ISBN 13 : 2889630269
Total Pages : 110 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Hormones, Neurotransmitters, and T-Cell Development in Health and Disease by : Wilson Savino

Download or read book Hormones, Neurotransmitters, and T-Cell Development in Health and Disease written by Wilson Savino and published by Frontiers Media SA. This book was released on 2019-11-01 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thymus physiology and T-cell homeostasis are controlled by hormones, neurotransmitters, cytokines and other factors that modulate stromal-cell interactions, influence thymocyte development and selection processes, survival and migration, between others. In the context of this Research Topic on “Hormones, Neurotransmitters, and T cell development in Health and Disease”, authors discuss the control of thymus physiology by glucocorticoids (GC), growth hormone (GH) and sex hormones, norepinephrine (NE) and other molecules that seem impact upon thymocyte/microenvironmental interactions, like galectin-3 (Gal-3) ephrins (Eph), extracellular matrix proteins and integrins (like VLA-5). Moreover, some of them draw attention to about how diverse maturation steps and/or the interactions between stromal and thymocytes can be affected in pathological states like diabetes or infections. As shown schematically in the figure, this topic highlight the following notions: 1) GH shows counterregulatory effects against GC rather than influence directly T cell homeostasis; 2) Interactions between sex hormones and noradrenergic secretion may influence thymus homeostasis and involution; 3) Gal-3 are crucial to thymocyte-stromal cell interactions and influence thymic architecture. Moreover, Gal-3 seem to be involved in the regulation of steroidogenic pathway; 4) Ephrins are crucial to assembly the thymic connections between thymocytes and the epithelial network, but have a relative importance in supporting normal thymopoyesis; 5) Pathologic situations like diabetes, or infectious diseases caused by parasites or bacteria alters the normal development of T-lymphocytes and might influence tolerance process. DN: double-negative (CD4-CD8) thymocytes; DP: double-positive (CD4+CD8+) thymocytes; SP: simple-positive thymocytes; LT: T lymphocyte; FN: fibronectin; PVS: peri-vascular space; BM: bone marrow; DBT: diabetes; Eph: Ephrins.

Sex Differences and Sex Steroids Effects in Musculoskeletal Health

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Publisher : Frontiers Media SA
ISBN 13 : 283250342X
Total Pages : 130 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Sex Differences and Sex Steroids Effects in Musculoskeletal Health by : Abdul Malik Tyagi

Download or read book Sex Differences and Sex Steroids Effects in Musculoskeletal Health written by Abdul Malik Tyagi and published by Frontiers Media SA. This book was released on 2022-11-02 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Diagnosis and Management of Ovarian Disorders

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Publisher : Elsevier
ISBN 13 : 008049451X
Total Pages : 568 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Diagnosis and Management of Ovarian Disorders by : Albert Altchek

Download or read book Diagnosis and Management of Ovarian Disorders written by Albert Altchek and published by Elsevier. This book was released on 2003-09-04 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated second edition of Diagnosis and Management of Ovarian Disorders provides thorough, yet succinct insight into the ever-changing realm of ovarian disorders. It presents a novel multidisciplinary approach to the subject as described by clinicians, surgeons, pathologists, basic scientists and related medical researchers. Topics covered include reproductive technology, early diagnosis of ovarian cancer, and management of menopause among others. The breadth of information provided by this book will appeal to clinicians and researchers involved in the study and treatment of ovarian disorders. KEY FEATURES * Includes updated information on early diagnosis of ovarian cancer * Reviews new diagnostic techniques for ovarian disorders * Discusses latest information on reproductive technology * Presents translational treatment linking laboratory research with clinical medicine