Separations For Biotechnology 2

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Separations for Biotechnology 2

Author : D. Leo Pyle
Publisher : Springer Science & Business Media
ISBN 13 : 9400907834
Total Pages : 659 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Separations for Biotechnology 2 by : D. Leo Pyle

Download or read book Separations for Biotechnology 2 written by D. Leo Pyle and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 659 pages. Available in PDF, EPUB and Kindle. Book excerpt: The challenge of bioseparations is to isolate and purify identified products from the dilute product broth produced from cell culture. Innovation in bioseparations technology is increasingly driven by the requirements imposed by the growing importance of production on a process scale of injectable-grade products, and economic pressures to improve the efficiency of downstream processing. As in other areas of technical change, science does not necessarily precede new technology: progress results from a complex and messy mixture of advances in understanding, ingenious ideas, novel techniques and chance discoveries. What is certain is that close interaction between academics and practitioners, biological scientists and process engineers is needed to solve the problems of bioseparations. The Second International Conference on Separations for Biotechnology at Reading, UK, in September 1990 set out to provide a critical multidisciplinary forum for the discussion of bioseparations. This volume contains the papers presented at the meeting. The meeting was organised around six themes with oral and poster presentations on the science and practice of bioseparations technology, and the same structure has been kept for this book. We have also included the texts of the keynote review paper by Professor Alan Michaels and the introductory review papers specially commissioned for the conference. Within each part of this book the review paper is followed by the contributed papers grouped alphabetically by their first author. All the original papers published here were accepted for publication after scientific refereeing.

Centrifugal Separations in Biotechnology

Author : Wallace Woon-Fong Leung
Publisher : Butterworth-Heinemann
ISBN 13 : 0081026358
Total Pages : 503 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Centrifugal Separations in Biotechnology by : Wallace Woon-Fong Leung

Download or read book Centrifugal Separations in Biotechnology written by Wallace Woon-Fong Leung and published by Butterworth-Heinemann. This book was released on 2020-03-13 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: Centrifugal Separations in Biotechnology, Second Edition, is the only book on the market devoted to centrifugal separation in biotechnology. Key topics covered include a full introduction to centrifugation, sedimentation and separation; detailed coverage of centrifuge types, including batch and semi-batch centrifuges, disk-stack and tubular decanter centrifuges; methods for increasing solids concentration; laboratory and pilot testing of centrifuges; selection and sizing centrifuges; scale-up of equipment, performance prediction and analysis of test results using numerical simulation. Centrifugal Separations in Biotechnology, Second Edition, provides guidance on troubleshooting and optimizing centrifuges, and then goes on to explore the commercial applications of centrifuges in biotechnology. It gives detailed process information and data to assist in the development of particular processes from existing systems. It is of value to professionals in the chemical, bioprocess, and biotech sectors, and all those concerned with bioseparation, bioprocessing, unit-operations and process engineering. Provides a comprehensive guide to centrifuges, their optimal development, and their operation in the biotechnology industry Updated throughout based on developments in industrial applications and advances in our understanding of centrifugal separations in biotechnology Discusses applications for the separation of proteins, DNA, mitochondria, ribosomes, lysosomes and other cellular elements Includes new sections on use of optimal polymer dosage in waste treatment, new centrifuge designs for applications in algae processing, biopharma, and more

Separation Processes in the Food and Biotechnology Industries

Author : A S Grandison
Publisher : Woodhead Publishing
ISBN 13 : 9781855732872
Total Pages : 306 pages
Book Rating : 4.7/5 (328 download)

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Book Synopsis Separation Processes in the Food and Biotechnology Industries by : A S Grandison

Download or read book Separation Processes in the Food and Biotechnology Industries written by A S Grandison and published by Woodhead Publishing. This book was released on 1996-01-15 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews methods and techniques for separating food components and products of the biotechnology industry. The introduction focuses on food composition and some of the conventional separation techniques. Subsequent chapters deal with each specific type or area of application individually and include information on the basic principles, industrial equipment available, commercial applications and an overview of research and development.

Separations for biotechnology : international conference ; 2

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (258 download)

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Book Synopsis Separations for biotechnology : international conference ; 2 by :

Download or read book Separations for biotechnology : international conference ; 2 written by and published by . This book was released on 1990 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biotechnology: Genetic engineering, mutagenesis, separation technology

Author : Jack G. Chirikjian
Publisher : Jones & Bartlett Learning
ISBN 13 : 9780867208962
Total Pages : 292 pages
Book Rating : 4.2/5 (89 download)

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Book Synopsis Biotechnology: Genetic engineering, mutagenesis, separation technology by : Jack G. Chirikjian

Download or read book Biotechnology: Genetic engineering, mutagenesis, separation technology written by Jack G. Chirikjian and published by Jones & Bartlett Learning. This book was released on 1995 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vol. II The work presented in these two volumes is the collaborative effort of over twenty undergraduate science faculty, whose common goal was to develop a text of unique and flexible laboratory activities focusing on the theory and practice of biotechnology for undergraduate students. The books are designed to provide flexibility for easy integration into any course in the life sciences with an experimental emphasis.

Highly Selective Separations in Biotechnology

Author : G. Street
Publisher : Springer Science & Business Media
ISBN 13 : 0751400513
Total Pages : 248 pages
Book Rating : 4.7/5 (514 download)

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Book Synopsis Highly Selective Separations in Biotechnology by : G. Street

Download or read book Highly Selective Separations in Biotechnology written by G. Street and published by Springer Science & Business Media. This book was released on 1994-08-31 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Success in meeting the challenge to produce the commercial products anticipated by the exploitation of biological processes depends upon provid ing effective separation protocols. Effectiveness can be measured in terms of selectivity, purity, resolution and validatory success. The major processing problems are associated with either the selective recovery of molecules which are present in low concentrations from complex mixtures or the selective removal of contaminants from the desired molecule. Central to the evolution of processes satisfying this demand are the regulatory requirements being imposed by governments on the purity of a product, especially in the health care market. Synthetic organic chemists are increasingly finding it advantageous to conduct one or more steps using either enzymic biotransformations where molecules with a single and consistent stereochemistry or chirality are required. The underlying princi ples behind the methods, techniques and processes currently being used and developed commercially rely upon the biospecific nature and properties of the desired molecule. When these factors are married to the more traditional techniques of precipitation, chromatography, liquid-liquid extraction and membrane processes, powerful tools emerge, allowing highly selective separations to be designed. The logical extension of these combinations is to apply genetic engineering techniques to influence the separations at a more fundamental and structural level by modifying the target protein at source, during its synthesis, to facilitate its separation in a given, selective manner, leading to the distinct possibility of producing 'designer' separation programmes.

Aqueous Two-Phase Systems

Author : Rajni Hatti-Kaul
Publisher : Springer Science & Business Media
ISBN 13 : 1592590284
Total Pages : 442 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Aqueous Two-Phase Systems by : Rajni Hatti-Kaul

Download or read book Aqueous Two-Phase Systems written by Rajni Hatti-Kaul and published by Springer Science & Business Media. This book was released on 2008-02-05 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: A mixture of two polymers, or one polymer and a salt, in an aqueous medium separates into two phases: this phenomenon is useful in biotechn- ogy for product separations. Separation of biological molecules and particles in these aqueous two-phase systems (ATPS) was initiated over 40 years ago by P.-Å. Albertsson, and later proved to be of immense utility in biochemical and cell biological research. A boost in the application of ATPS was seen when problems of separations in biotechnology processes were encountered. Its simplicity, biocompatibility, and amenability to easy scaleup operations make the use of ATPS very attractive for large-scale bioseparations. Despite the advantages ATPS enjoys over other separation techniques, the application of two-phase systems has for a long time been confined to selected labora- ries. Recent years have, however, shown a trend in which increasing numbers of researchers employ two-phase partitioning techniques in both basic and applied research.

Separation Processes in Biotechnology

Author : Juan A. Asenjo
Publisher : CRC Press
ISBN 13 : 100010432X
Total Pages : 824 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Separation Processes in Biotechnology by : Juan A. Asenjo

Download or read book Separation Processes in Biotechnology written by Juan A. Asenjo and published by CRC Press. This book was released on 2020-08-26 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited to avoid duplication and favor comprehensiveness, 20 contributors detail the recovery, separation, and purification operations of bioprocess technology. Individual chapters in this classic yet still highly relevant work emphasize concepts that are becoming more and more important when applied to the large scale versions of techniques that are considered well established. Aside from fully discussing processes, Separation Processes in Biotechnology includes sections on concentration separation and operation, purification operations, and product release and recovery. It also discusses plant operation and equipment and delves into economic considerations

Separations for Biotechnology 3

Author : D. L. Pyle
Publisher :
ISBN 13 :
Total Pages : 634 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Separations for Biotechnology 3 by : D. L. Pyle

Download or read book Separations for Biotechnology 3 written by D. L. Pyle and published by . This book was released on 1994 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioseparation is a technique by which the products of fermentations or biotransformations are recovered for subsequent use. This volume explores the technical problems posed by bioprocessing, and the importance of the recovery of pure biological products for product safety and quality.

Membrane Separations in Biotechnology

Author : William K. Wang
Publisher : CRC Press
ISBN 13 : 1482289881
Total Pages : 432 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Membrane Separations in Biotechnology by : William K. Wang

Download or read book Membrane Separations in Biotechnology written by William K. Wang and published by CRC Press. This book was released on 2001-04-03 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text details the relationship between membrane technology and bioprocesses, discussing applications. This second edition refines and optimizes key features of the first edition - and features new illustrative case studies. The book examines advantages and disadvantages of using standard and new membrane technologies; analyzes a wide range of a

Separations for Biotechnology

Author :
Publisher :
ISBN 13 :
Total Pages : 634 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Separations for Biotechnology by :

Download or read book Separations for Biotechnology written by and published by . This book was released on 1994 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Highly Selective Separations in Biotechnology

Author : G. Street
Publisher : Springer Science & Business Media
ISBN 13 : 940111322X
Total Pages : 242 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Highly Selective Separations in Biotechnology by : G. Street

Download or read book Highly Selective Separations in Biotechnology written by G. Street and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Success in meeting the challenge to produce the commercial products anticipated by the exploitation of biological processes depends upon provid ing effective separation protocols. Effectiveness can be measured in terms of selectivity, purity, resolution and validatory success. The major processing problems are associated with either the selective recovery of molecules which are present in low concentrations from complex mixtures or the selective removal of contaminants from the desired molecule. Central to the evolution of processes satisfying this demand are the regulatory requirements being imposed by governments on the purity of a product, especially in the health care market. Synthetic organic chemists are increasingly finding it advantageous to conduct one or more steps using either enzymic biotransformations where molecules with a single and consistent stereochemistry or chirality are required. The underlying princi ples behind the methods, techniques and processes currently being used and developed commercially rely upon the biospecific nature and properties of the desired molecule. When these factors are married to the more traditional techniques of precipitation, chromatography, liquid-liquid extraction and membrane processes, powerful tools emerge, allowing highly selective separations to be designed. The logical extension of these combinations is to apply genetic engineering techniques to influence the separations at a more fundamental and structural level by modifying the target protein at source, during its synthesis, to facilitate its separation in a given, selective manner, leading to the distinct possibility of producing 'designer' separation programmes.

Separation Processes in Biotechnology

Author : Juan A. Asenjo
Publisher : CRC Press
ISBN 13 : 1000147533
Total Pages : 828 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Separation Processes in Biotechnology by : Juan A. Asenjo

Download or read book Separation Processes in Biotechnology written by Juan A. Asenjo and published by CRC Press. This book was released on 2020-08-26 with total page 828 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited to avoid duplication and favor comprehensiveness, 20 contributors detail the recovery, separation, and purification operations of bioprocess technology. Individual chapters in this classic yet still highly relevant work emphasize concepts that are becoming more and more important when applied to the large scale versions of techniques that are considered well established. Aside from fully discussing processes, Separation Processes in Biotechnology includes sections on concentration separation and operation, purification operations, and product release and recovery. It also discusses plant operation and equipment and delves into economic considerations

Engineering Processes for Bioseparations

Author : LAURENCE R. WEATHERLEY
Publisher : Elsevier
ISBN 13 : 148329210X
Total Pages : 305 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Engineering Processes for Bioseparations by : LAURENCE R. WEATHERLEY

Download or read book Engineering Processes for Bioseparations written by LAURENCE R. WEATHERLEY and published by Elsevier. This book was released on 2013-10-22 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of biotechnology in chemical synthesis offers up numerous advantages to the engineer in the process industries, but it also presents a number of fundamental challenges and difficulties which impinge directly on separation process requirements. The use of biochemical separations has grown significantly during the past decade, and is especially used in process industries such as healthcare and food processing. However it is becoming increasingly more important in areas such as recycling and waste-water treatment and as industry shifts towards cleaner processes biochemical separations will continue to grow. The two main objectives of this book are to focus on the application of existing separation process techniques to the recovery and purification of biologically derived products and to examine the state of knowledge of new techniques which have future potential. Within these objectives the complexities and breadth of problems associated with biological separations are discussed, specific engineering techniques are featured and their adaptation to biochemical separations are highlighted.

Partitioning In Aqueous Two – Phase System

Author : Harry Walter
Publisher : Elsevier
ISBN 13 : 0323142915
Total Pages : 730 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Partitioning In Aqueous Two – Phase System by : Harry Walter

Download or read book Partitioning In Aqueous Two – Phase System written by Harry Walter and published by Elsevier. This book was released on 2012-12-02 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt: Partitioning in Aqueous Two-Phase Systems: Theory, Methods, Uses, and Applications to Biotechnology is a collection of papers that discusses the applications of aqueous two-phase systems to problems of separation and extraction of macromolecules, organelles, and cells. Papers focus on the theoretical basis and the practical details of the procedures used. Some of the papers describe in one or a few steps how two components can be separated by the investigator manipulating their partitions so that one component is in one phase and the other component is in the other phase or at the interface. Investigators can also avail of developed batch extractions for plant organelles, cell membranes, nucleic acids, and proteins. The book cites as an example the partitioning of right-side-out and inside-out vesicles (obtained from fragments of thylakoid membranes) to the top and bottom phases, respectively, of a Dx-PEG system. Other papers describe the use of the countercurrent distribution when single extraction steps are not sufficient to produce a separation in materials that do not differ greatly in their partitioning behavior. The collection can prove valuable for bio-chemists, cellular biologists, micro-biologists, and developmental biologists.

A Research Agenda for Transforming Separation Science

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309491703
Total Pages : 115 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis A Research Agenda for Transforming Separation Science by : National Academies of Sciences, Engineering, and Medicine

Download or read book A Research Agenda for Transforming Separation Science written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-10-30 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: Separation science plays a critical role in maintaining our standard of living and quality of life. Many industrial processes and general necessities such as chemicals, medicines, clean water, safe food, and energy sources rely on chemical separations. However, the process of chemical separations is often overlooked during product development and this has led to inefficiency, unnecessary waste, and lack of consensus among chemists and engineers. A reevaluation of system design, establishment of standards, and an increased focus on the advancement of separation science are imperative in supporting increased efficiency, continued U.S. manufacturing competitiveness, and public welfare. A Research Agenda for Transforming Separation Science explores developments in the industry since the 1987 National Academies report, Separation and Purification: Critical Needs and Opportunities. Many needs stated in the original report remain today, in addition to a variety of new challenges due to improved detection limits, advances in medicine, and a recent emphasis on sustainability and environmental stewardship. This report examines emerging chemical separation technologies, relevant developments in intersecting disciplines, and gaps in existing research, and provides recommendations for the application of improved separation science technologies and processes. This research serves as a foundation for transforming separation science, which could reduce global energy use, improve human and environmental health, and advance more efficient practices in various industries.

The Science and Application of Aqueous Two-Phase Systems and Liquid-Liquid Phase Separation in Biotechnology and Bioengineering

Author : John Paul Frampton
Publisher : Frontiers Media SA
ISBN 13 : 288963356X
Total Pages : 117 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis The Science and Application of Aqueous Two-Phase Systems and Liquid-Liquid Phase Separation in Biotechnology and Bioengineering by : John Paul Frampton

Download or read book The Science and Application of Aqueous Two-Phase Systems and Liquid-Liquid Phase Separation in Biotechnology and Bioengineering written by John Paul Frampton and published by Frontiers Media SA. This book was released on 2020-01-13 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: The phase separation of incompatible liquids has been a topic of significant importance in chemical and industrial engineering for many years. Well-understood examples of this phenomenon include the phase separation of oil with water and the phase separation of non-polar organic solvents with water. Similar behavior is observed when aqueous solutions of two or more incompatible polymers or polymers and salts are mixed. In these mixtures (referred to as aqueous two-phase systems), the separated phases are composed mostly of water. Aqueous two-phase systems have been used extensively for the extraction of high-value biological products from mixtures of biological materials. In recent years, aqueous two-phase systems have also found increased use as materials for streamlining and improving the capabilities of cell and molecular assays, and for the design of advanced cell culture systems. Similar behavior of biological materials in living systems has also been observed, with emerging roles in cell physiology.