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Self Assembling Peptide Nanotubes
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Book Synopsis Self-Assembled Peptide Nanostructures by : Jaime Castillo
Download or read book Self-Assembled Peptide Nanostructures written by Jaime Castillo and published by CRC Press. This book was released on 2012-11-21 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: The self-organization of bionanostructures into well-defined functional machineries found in nature has been a priceless source of ideas for researchers. The molecules of life, proteins, DNA, RNA, etc., as well as the structures and forms that these molecules assume serve as rich sources of ideas for scientists or engineers who are interested in de
Book Synopsis Self-assembling Peptide Nanotubes by : Jeffrey Dale Hartgerink
Download or read book Self-assembling Peptide Nanotubes written by Jeffrey Dale Hartgerink and published by . This book was released on 1999 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Self-assembling peptide nanotubes are a new class of supramolecular structures based on the hydrogen bonded stacking of cyclic peptides with an even number of alternating D/L amino acids. This stacking forms an open channel of between 5 and 13Å depending on the number of amino acids making up the peptide ring. Because their preparation is based on the self-assembly of relatively small, easily prepared subunits consisting of amino acids, the diameter of the channel formed and the outer surface chemistry of the nanotube can be readily tailored simply by altering the number and choice of amino acids. This flexibility has allowed the preparation of peptide nanotubes with a wide variety of characteristics. This thesis describes the design, preparation, characterization and functional application of the subset of peptide nanotubes that form well ordered (crystalline) parallel packed arrays. Within this subset of peptide nanotubes two classes, charged and uncharged, are considered. Chapter 1 reviews the work leading up to the preparation of the first self-assembling peptide nanotube in 1993 and the current state of the field. Chapter 2 describes uncharged peptide nanotubes prepared from the cyclic peptides cyclo-[(Gln- D -Xxx)4] (Xxx = Ala, Val, Leu, Phe) by a solvent induced mechanism. Chapter 3 describes three nanotubes prepared from cyclo-[(Xxx-D -Leu) 4 ] (Xxx = Glu, Lys) by an electrostatic mediated and pH controlled assembly. Finally, chapter 4 discusses results obtained using the outer surface of carboxylate decorated nanotubes as a biomineralization directing agent in the reduction of transition metal salts.
Book Synopsis Peptide Self-Assembly and Engineering by : Xuehai Yan
Download or read book Peptide Self-Assembly and Engineering written by Xuehai Yan and published by John Wiley & Sons. This book was released on 2024-02-09 with total page 933 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptide Self-Assembly and Engineering State-of-the-art research in peptide self-assembly, with coverage of fundamental aspects of how peptides self-assemble and an extensive number of applications Peptide Self-Assembly and Engineering: Fundamentals, Structures, and Applications (2V set) covers the latest progresses in the field of peptide self-assembly and engineering, including the fundamental principles of peptide self-assembly, new theory of nucleation and growth, thermodynamics and kinetics, materials design rules, and precisely controlled structures and unique functions. The broad contents from this book enable readers to obtain a systematical and comprehensive knowledge in the field of peptide self-assembly and engineering. Contributed by the leading scientists and edited by a highly qualified academic and an authority in the field, Peptide Self-Assembly and Engineering includes information on: Emerging areas in peptide assembly, such as immune agents, bioelectronics, energy conversion, flexible sensors, biomimetic catalysis, and more Existing applications in biomedical engineering, nanotechnology, and photoelectronics, including tissue engineering, drug delivery, and biosensing devices History of peptide self-assembly for design of functional materials and peptides’ unique mechanical, optical, electronic, and biological properties Various solvent conditions, such as pH, ionic strength, and polarity, that can affect the structure and stability of peptide assemblies A very comprehensive reference covering the latest progresses in the field of peptide self-assembly and engineering, Peptide Self-Assembly and Engineering is an essential resource for all scientists performing research intersecting with the subject, including biochemists, biotechnologists, pharmaceutical chemists, protein chemists, materials scientists, and medicinal chemists.
Book Synopsis Self-assembling Cyclic D, L-peptide Nanotubes as Synthetic Transmembrane Channels from Chemical, Biological and Practical Perspectives by : Hui Sun Kim
Download or read book Self-assembling Cyclic D, L-peptide Nanotubes as Synthetic Transmembrane Channels from Chemical, Biological and Practical Perspectives written by Hui Sun Kim and published by . This book was released on 1999 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptide nanotubes are cylindrical, open-ended, ß-sheet supramolecular structures formed from the self-assembly of cyclic peptides that can adopt a flat-ring conformation. In this work, the principles of molecular self-assembly in the lipid bilayer environment are explored through the study of the cyclic peptide nanotubes as synthetic transmembrane channels. Structural evidence for the cyclic peptides as a transmembrane channel is established through an orientational FT-IR analysis of the tubular peptide assembly in the lipid membrane. A biophysical investigation of substituted cyclic peptides using vesicular transport assays, single channel conductance measurements, and attenuated total reflectance FT-IR spectroscopy shows the significant impact of subunit sequence variations on the channel activity and structural organization of the supramolecular assembly in the membrane environment. The potential utility of the cyclic peptides is investigated through a study of their structure and behavior at interfaces, and by the design and synthesis of cyclic peptides with biological activity.
Book Synopsis Peptide-Based Materials by : Timothy Deming
Download or read book Peptide-Based Materials written by Timothy Deming and published by Springer Science & Business Media. This book was released on 2012-01-10 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis of Polypeptides by Ring-Opening Polymerization of α-Amino Acid N-Carboxyanhydrides, by Jianjun Cheng and Timothy J. Deming.- Peptide Synthesis and Self-Assembly, by S. Maude, L. R. Tai, R. P. W. Davies, B. Liu, S. A. Harris, P. J. Kocienski and A. Aggeli.- Elastomeric Polypeptides, by Mark B. van Eldijk, Christopher L. McGann, Kristi L. Kiick andJan C. M. van Hest.- Self-Assembled Polypeptide and Polypeptide Hybrid Vesicles: From Synthesis to Application, by Uh-Joo Choe, Victor Z. Sun, James-Kevin Y. Tan and Daniel T. Kamei.- Peptide-Based and Polypeptide-Based Hydrogels for Drug Delivery and Tissue Engineering, by Aysegul Altunbas and Darrin J. Pochan.-
Book Synopsis Self-Assembly of Peptides, Peptoids, Sugars, & Dendrimers by : Martin Conda-Sheridan
Download or read book Self-Assembly of Peptides, Peptoids, Sugars, & Dendrimers written by Martin Conda-Sheridan and published by American Chemical Society. This book was released on 2023-07-05 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this primer is to discuss the chemistry of self-assembly. It introduces some of the common reactions you need to know to prepare a desired molecule that can self-assemble (or various molecules that can be mixed to create a self-assembled system). The focus is on four self-assembled systems composed of peptides, peptoids, sugars, and dendrimers.
Book Synopsis Peptide Bionanomaterials by : Mohamed A. Elsawy
Download or read book Peptide Bionanomaterials written by Mohamed A. Elsawy and published by Springer Nature. This book was released on 2023-08-28 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular self-assembly has been exploited by nature for developing the higher functional macromolecular structures of both the genome and proteome. Inspired by nature, there has been a surge of research, in the last two decades, for the molecular engineering of peptide-based self-assembling nanostructures, adopting the bottom-up design approach. This book gives the reader an overview on the design rules for de novo self-assembling peptide and reviews the diverse range of bioinspired peptide nanostructures such as β-sheet and β-hairpin, α-helical and coiled coil, self-assembling short peptides and peptidomimetics, collagen-based and elastin-like peptides, silk peptides, peptide amphiphiles, peptides co-polymers and others. The book also covers the wide variety of responsive and functional biomaterials that have been innovated based on those nanostructures for various applications ranging from tissue engineering, therapeutics and drug delivery to antimicrobial nanomaterials and biosensors. Finally, the book also discusses the peptide bionanomaterials global market and the future of the emerging industry. Chapter “Characterization of Peptide-Based Nanomaterials” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Book Synopsis Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair by : Mario Barbosa
Download or read book Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair written by Mario Barbosa and published by Woodhead Publishing. This book was released on 2017-09-25 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair highlights the various important considerations that go into biomaterial development, both in terms of fundamentals and applications. After covering a general introduction to protein and cell interactions with biomaterials, the book discusses proteins in biomaterials that mimic the extracellular matrix (ECM). The properties, fabrication and application of peptide biomaterials and protein-based biomaterials are discussed in addition to in vivo and in vitro studies. This book is a valuable resource for researchers, scientists and advanced students interested in biomaterials science, chemistry, molecular biology and nanotechnology. - Presents an all-inclusive and authoritative coverage of the important role which protein and peptides play as biomaterials for tissue regeneration - Explores protein and peptides from the fundamentals, to processing and applications - Written by an international group of leading biomaterials researchers
Book Synopsis Nanoscale Assembly by : Wilhelm T.S. Huck
Download or read book Nanoscale Assembly written by Wilhelm T.S. Huck and published by Springer Science & Business Media. This book was released on 2006-07-11 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology has received tremendous interest over the last decade, not only from the scientific community but also from a business perspective and from the general public. Although nanotechnology is still at the largely unexplored frontier of science, it has the potential for extremely exciting technological innovations that will have an enormous impact on areas as diverse as information technology, medicine, energy supply and probably many others. The miniturization of devices and structures will impact the speed of devices and information storage capacity. More importantly, though, nanotechnology should lead to completely new functional devices as nanostructures have fundamentally different physical properties that are governed by quantum effects. When nanometer sized features are fabricated in materials that are currently used in electronic, magnetic, and optical applications, quantum behavior will lead to a set of unprecedented properties. The interactions of nanostructures with biological materials are largely unexplored. Future work in this direction should yield enabling technologies that allows the study and direct manipulation of biological processes at the (sub) cellular level.
Book Synopsis Protein Self-Assembly by : Jennifer J. McManus
Download or read book Protein Self-Assembly written by Jennifer J. McManus and published by Humana. This book was released on 2020-08-08 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores experimental and computational approaches to measuring the most widely studied protein assemblies, including condensed liquid phases, aggregates, and crystals. The chapters in this book are organized into three parts: Part One looks at the techniques used to measure protein-protein interactions and equilibrium protein phases in dilute and concentrated protein solutions; Part Two describes methods to measure kinetics of aggregation and to characterize the assembled state; and Part Three details several different computational approaches that are currently used to help researchers understand protein self-assembly. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Protein Self-Assembly: Methods and Protocols is a valuable resource for researchers who are interested in learning more about this developing field.
Book Synopsis Self-Assembled Nanomaterials I by : Toshimi Shimizu
Download or read book Self-Assembled Nanomaterials I written by Toshimi Shimizu and published by Springer Science & Business Media. This book was released on 2008-09-26 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text was ranked by ISI as having the Highest Impact Factor of all publications within Polymer Science. It is a collection of concise reports on the physics and chemistry of polymers.
Book Synopsis Self-assembling Biomaterials by : Helena S. Azevedo
Download or read book Self-assembling Biomaterials written by Helena S. Azevedo and published by Woodhead Publishing. This book was released on 2018-04-17 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt: Self-assembling biomaterials: molecular design, characterization and application in biology and medicine provides a comprehensive coverage on an emerging area of biomaterials science, spanning from conceptual designs to advanced characterization tools and applications of self-assembling biomaterials, and compiling the recent developments in the field. Molecular self-assembly, the autonomous organization of molecules, is ubiquitous in living organisms and intrinsic to biological structures and function. Not surprisingly, the exciting field of engineering artificial self-assembling biomaterials often finds inspiration in Biology. More important, materials that self-assemble speak the language of life and can be designed to seamlessly integrate with the biological environment, offering unique engineering opportunities in bionanotechnology. The book is divided in five parts, comprising design of molecular building blocks for self-assembly; exclusive features of self-assembling biomaterials; specific methods and techniques to predict, investigate and characterize self-assembly and formed assemblies; different approaches for controlling self-assembly across multiple length scales and the nano/micro/macroscopic properties of biomaterials; diverse range of applications in biomedicine, including drug delivery, theranostics, cell culture and tissue regeneration. Written by researchers working in self-assembling biomaterials, it addresses a specific need within the Biomaterials scientific community. - Explores both theoretical and practical aspects of self-assembly in biomaterials - Includes a dedicated section on characterization techniques, specific for self-assembling biomaterials - Examines the use of dynamic self-assembling biomaterials
Book Synopsis Self-Assembled Peptide Nanostructures by : Jaime Castillo
Download or read book Self-Assembled Peptide Nanostructures written by Jaime Castillo and published by CRC Press. This book was released on 2012-11-21 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: The self-organization of bionanostructures into well-defined functional machineries found in nature has been a priceless source of ideas for researchers. The molecules of life, proteins, DNA, RNA, etc., as well as the structures and forms that these molecules assume serve as rich sources of ideas for scientists or engineers who are interested in developing bio-inspired materials for innovations in biomedical fields. In nature, molecular self-assembly is a process by which complex three-dimensional structures with well-defined functions are constructed, starting from simple building blocks such as proteins and peptides. This book introduces readers to the theory and mechanisms of peptide self-assembly processes. The authors present the more common peptide self-assembled building blocks and discuss how researchers from different fields can apply self-assembling principles to bionanotechnology applications. The advantages and challenges are mentioned together with examples that reflect the state of the art of the use of self-assembled peptide building blocks in nanotechnology.
Book Synopsis Cyclic Peptide Nanotubes by : Thomas Dudley Clark
Download or read book Cyclic Peptide Nanotubes written by Thomas Dudley Clark and published by . This book was released on 1998 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent reports have shown that cyclic peptides composed of an even number of alternating sc D- and sc L-amino acids can adopt flat, disc-like conformations and stack through backbone-backbone hydrogen-bonding to form extended nanotubular structures. The present work details a general strategy for limiting this self-assembly process through backbone alkylation, thereby preventing formation of insoluble hydrogen-bonded aggregates and giving rise to dimeric peptide nanocylinders. The resulting peptide dimers are shown to self-assemble both in solution and the solid state through the expected antiparallel beta-sheet hydrogen-bonding network. Scope and limitations are explored through spectroscopic and x-ray diffraction studies of twenty cyclic peptides varying in cyclic peptide ring size, location and identity of backbone alkyl substituents, and amino acid composition. Additionally, dimer-forming peptides bearing reactive side chain functinalities are shown to undergo selective covalent capture through either intermolecular ring-forming olefin metathesis or disulfide bond formation. Noncovalent assembly is used to favor covalent dimer formation at the expense of higher oligomers. Finally, related cyclic peptides composed of homochiral alpha-unsubstituted-beta-chiral-beta-amino acids (cyclic beta-peptides) bearing suitable hydrophobic side chains are shown to form transmembrane ion channels with potassium transport rates nearly twice that of gramicidin A.
Book Synopsis Peptides and Peptide-based Biomaterials and their Biomedical Applications by : Anwar Sunna
Download or read book Peptides and Peptide-based Biomaterials and their Biomedical Applications written by Anwar Sunna and published by Springer. This book was released on 2017-10-26 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solid-binding peptides have been used increasingly as molecular building blocks in nanobiotechnology as they can direct the assembly and functionalisation of a diverse range of materials and have the ability to regulate the synthesis of nanoparticles and complex nanostructures. Nanostructured materials such as β-sheet fibril-forming peptides and α-helical coiled coil systems have displayed many useful properties including stimulus-responsiveness, modularity and multi-functionality, providing potential technological applications in tissue engineering, antimicrobials, drug delivery and nanoscale electronics. The current situation with respect to self-assembling peptides and bioactive matrices for regenerative medicine are reviewed, as well as peptide-target modeling and an examination of future prospects for peptides in these areas.
Book Synopsis Piezoelectric Nanomaterials for Biomedical Applications by : Gianni Ciofani
Download or read book Piezoelectric Nanomaterials for Biomedical Applications written by Gianni Ciofani and published by Springer Science & Business Media. This book was released on 2012-03-31 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoscale structures and materials have been explored in many biological applications because of their novel and impressive physical and chemical properties. Such properties allow remarkable opportunities to study and interact with complex biological processes. This book analyses the state of the art of piezoelectric nanomaterials and introduces their applications in the biomedical field. Despite their impressive potentials, piezoelectric materials have not yet received significant attention for bio-applications. This book shows that the exploitation of piezoelectric nanoparticles in nanomedicine is possible and realistic, and their impressive physical properties can be useful for several applications, ranging from sensors and transducers for the detection of biomolecules to “sensible” substrates for tissue engineering or cell stimulation.
Book Synopsis Materials Nanoarchitectonics by : Katsuhiko Ariga
Download or read book Materials Nanoarchitectonics written by Katsuhiko Ariga and published by Elsevier. This book was released on 2023-12-07 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: Materials Nanoarchitectonics: From Integrated Molecular Systems to Advanced Devices provides the latest information on the design and molecular manipulation of self-organized hierarchically structured systems using tailor-made nanoscale materials as structural and functional units. The book is organized into three main sections that focus on molecular design of building blocks and hybrid materials, formation of nanostructures, and applications and devices. Bringing together emerging materials, synthetic aspects, nanostructure strategies, and applications, the book aims to support further progress, by offering different perspectives and a strong interdisciplinary approach to this rapidly growing area of innovation. This is an extremely valuable resource for researchers, advanced students, and scientists in industry, with an interest in nanoarchitectonics, nanostructures, and nanomaterials, or across the areas of nanotechnology, chemistry, surface science, polymer science, electrical engineering, physics, chemical engineering, and materials science. - Offers a nanoarchitectonic perspective on emerging fields, such as metal-organic frameworks, porous polymer materials, or biomimetic nanostructures - Discusses different approaches to utilizing "soft chemistry" as a source for hierarchically organized materials - Offers an interdisciplinary approach to the design and construction of integrated chemical nano systems - Discusses novel approaches towards the creation of complex multiscale architectures
