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Scanning Microwave Induced Acoustic Tomography
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Book Synopsis Scanning Microwave Induced Acoustic Tomography by :
Download or read book Scanning Microwave Induced Acoustic Tomography written by and published by . This book was released on 2001 with total page 39 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the previous report in 2002, we have published five peer-reviewed journal articles and delivered 12 invited talks. For the invited plenary talk given at UK, all travel related expenses were covered by the conference host. The combination of ultrasound and microwave has provided us a unique opportunity for early-cancer imaging with high resolution and high contrast. A good imaging modality should have both high contrast and high spatial resolution. Our imaging technology combines synergistically radiofrequency waves and ultrasonic waves, where the former provides high contrast and the latter provides high spatial resolution. Only non-ionizing radiation is used. No painful breast compression is' required. In addition, our images are free of speckle artifacts, which are prevalent in conventional ultrasound images. Our ultimate goal is to detect early breast cancer.
Book Synopsis Microwave-induced thermoacoustic imaging/photoacoustic imaging by : Huan Qin
Download or read book Microwave-induced thermoacoustic imaging/photoacoustic imaging written by Huan Qin and published by Frontiers Media SA. This book was released on 2023-02-13 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Microwave-induced Thermoacoustic Tomography by : Xing Jin
Download or read book Microwave-induced Thermoacoustic Tomography written by Xing Jin and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This research is primarily focused on developing potential applications for microwaveinduced thermoacoustic tomography and correcting for image degradations caused by acoustic heterogeneities. Microwave-induced thermoacoustic tomography was first used to verify the feasibility of noninvasively detecting the coagulated damage based on different dielectric properties between normal tissue and lesion treated with high intensity focused ultrasound. Good image contrasts were obtained for the lesions. A comparison of the size of the lesion measured with microwave-induced thermoacoustic tomography and the size measured by a gross pathologic photograph was presented to verify the effectiveness the proposed method. Clinical data for breast tumors were also collected to verify the feasibility of using microwave-induced thermoacoustic tomography in breast cancer imaging. Next, the effects of acoustic heterogeneities on microwave-induced thermoacoustic tomography in weakly refractive medium were investigated. A correction method based on ultrasonic transmission tomography was proposed to correct for the image distortion. Numerical simulations and phantom experiments verify the effectiveness of this correction method. The compensation is important for obtaining higher resolution images of small tumors in acoustically heterogeneous tissues. Finally, the effects of the highly refractive skull on transcranial brain imaging were studied. A numerical method, which considered wave reflection and refraction at the skull surfaces, was proposed to compensate for the image degradation. The results obtained with the proposed model were compared with the results without considering the skull-induced distortion to evaluate the skull-induced effects on the image reconstruction. It was demonstrated by numerical simulations and phantom experiments that the image quality could be improved by incorporating the skull shape and acoustic properties into image reconstruction. This compensation method is important when the thickness of skull cannot be neglected in transcranial brain imaging.
Book Synopsis Experimental Study of Microwave-induced Thermoacoustic Imaging by : Ryan T. Jacobs
Download or read book Experimental Study of Microwave-induced Thermoacoustic Imaging written by Ryan T. Jacobs and published by . This book was released on 2016 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Photoacoustic Imaging and Spectroscopy by : Lihong V. Wang
Download or read book Photoacoustic Imaging and Spectroscopy written by Lihong V. Wang and published by CRC Press. This book was released on 2017-12-19 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Photoacoustics promises to revolutionize medical imaging and may well make as dramatic a contribution to modern medicine as the discovery of the x-ray itself once did. Combining electromagnetic and ultrasonic waves synergistically, photoacoustics can provide deep speckle-free imaging with high electromagnetic contrast at high ultrasonic resolution and without any health risk. While photoacoustic imaging is probably the fastest growing biomedical imaging technology, this book is the first comprehensive volume in this emerging field covering both the physics and the remarkable noninvasive applications that are changing diagnostic medicine. Bringing together the leading pioneers in this field to write about their own work, Photoacoustic Imaging and Spectroscopy is the first to provide a full account of the latest research and developing applications in the area of biomedical photoacoustics. Photoacoustics can provide functional sensing of physiological parameters such as the oxygen saturation of hemoglobin. It can also provide high-contrast functional imaging of angiogenesis and hypermetabolism in tumors in vivo. Discussing these remarkable noninvasive applications and so much more, this reference is essential reading for all researchers in medical imaging and those clinicians working at the cutting-edge of modern biotechnology to develop diagnostic techniques that can save many lives and just as importantly do no harm.
Book Synopsis Multi-wave Electromagnetic-Acoustic Sensing and Imaging by : Fei Gao
Download or read book Multi-wave Electromagnetic-Acoustic Sensing and Imaging written by Fei Gao and published by Springer. This book was released on 2017-02-01 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis covers a broad range of interdisciplinary topics concerning electromagnetic-acoustic (EM-Acoustic) sensing and imaging, mainly addressing three aspects: fundamental physics, critical biomedical applications, and sensing/imaging system design. From the fundamental physics perspective, it introduces several highly interesting EM-Acoustic sensing and imaging methods, which can potentially provide higher sensitivity, multi-contrast capability, and better imaging performance with less distortion. From the biomedical applications perspective, the thesis introduces useful techniques specifically designed to address selected challenging biomedical applications, delivering rich contrast, higher sensitivity and finer spatial resolution. Both phantom and ex vivo experiments are presented, and in vivo validations are progressing towards real clinical application scenarios. From the sensing and imaging system design perspective, the book proposes several promising sensing/imaging prototypes. Further, it offers concrete suggestions that could bring these systems closer to becoming “real” products and commercialization, such as replacing costly lasers with portable laser diodes, or integrating transmitting and data recording on a single board.
Book Synopsis Optical-Thermal Response of Laser-Irradiated Tissue by : Ashley J. Welch
Download or read book Optical-Thermal Response of Laser-Irradiated Tissue written by Ashley J. Welch and published by Springer Science & Business Media. This book was released on 2011-01-15 with total page 951 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition maintains the standard of excellence established in the first edition, while adjusting the content to reflect changes in tissue optics and medical applications since 1995. The material concerning light propagation now contains new chapters devoted to electromagnetic theory for coherent light. The material concerning thermal laser-tissue interactions contains a new chapter on pulse ablation of tissue. The medical applications section now includes several new chapters on Optical Coherent Tomography, acoustic imaging, molecular imaging, forensic optics and nerve stimulation. A detailed overview is provided of the optical and thermal response of tissue to laser irradiation along with diagnostic and therapeutic examples including fiber optics. Sufficient theory is included in the book so that it is suitable for a one or two semester graduate or for senior elective courses. Material covered includes (1) light propagation and diagnostic application; (2) the thermal response of tissue and therapeutic application; (3) denaturation; and (4) ablation. The theory and applications provide researchers with sufficient detail that this volume will become the primary reference for laser-tissue interactions and medical applications.
Book Synopsis The Design of Compact Microwave-induced Thermoacoustic Imaging Systems for Medical Screening Applications by : Hao Nan
Download or read book The Design of Compact Microwave-induced Thermoacoustic Imaging Systems for Medical Screening Applications written by Hao Nan and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical imaging can create visual representations of the internal structure of a body for clinical analysis and therapeutic intervention. It has been successful in reducing the mortality rate of most diseases. However, the access to advanced imaging tools is limited to hospitals due to size, cost, and other constraints, which limits the screening frequency and widespread use, leading to missing some fast-growing and often fatal types of diseases. For example, the screening interval of mammography is limited by a desire to restrict the ionizing radiation due to X-ray, as well as secondary concerns of screening cost and the false positive rate. From a sampling point of view, a Nyquist screening is required to enable continuous monitoring and provide meaningful information for diagnosis. It needs significant innovations to scale the system into a compact dimension with low cost, to enable portable and even handheld operation without ionization radiation. The medical imaging community has long been in pursuit of such a suitable handheld imaging system which provides high contrast and resolution for point-of-care frequent screening and diagnostics. One such promising candidate is microwave-induced thermoacoustic (TA) imaging. As a multi-physics hybrid modality, TA imaging provides dielectric/conductivity contrast and ultrasound resolution at the same time. Ultrasound signals generated from thermal expansion differentials in soft tissue (the thermo-elastic response) are detected by a scanning single-element transducer or an ultrasonic array to form images. Combining microwave and acoustics provides the extra benefit of enabling a handheld and portable form factor, due to the integration potential of both modalities. This dissertation describes beamforming and coherent processing in TA imaging for improved signal generation and detection to enable handheld operations with low power and a small form factor. In TA beamforming, we increase the deposited radio frequency (RF) power to the target volume at depth and avoid excessive heating of the skin or surface by transmitting RF power from multiple locations instead of a single high-power element. With a phased array, we steer and control the RF focal point across the target region by tuning the phase of each channel. Spatial power combining can significantly improve TA signal generation at depth due to the coherent summation of E fields from excitation elements. In another direction, I perform coherent processing in TA imaging by exciting the target with the microwave of longer duration and much lower peak power compared to conventional pulse approaches. With matched-filter processing, we can reconstruct the target pulse response as well as achieving significant signal-to-noise ratio improvement by exploiting the amplitude and phase in the frequency domain. The coherent processing further reduces the requirements of the RF power source and enables fully solid-state implementation of TA imaging. The dissertation also presents a programmable integrated wideband RF transmitter for TA imaging based on the ST 55~nm BiCMOS technology. With the designed chip, the TA imaging system is scaled to a small form factor, while it can operate in both coherent mode and conventional pulse mode as well as simultaneous imaging and spectroscopy capability. By exploiting the different responses of tissues across microwave excitation frequency, TA spectroscopy provides another degree of freedom to enhance contrast, differentiate materials and help diagnosis. In addition, this dissertation demonstrates non-invasive temperature monitoring with TA imaging by exploiting temperature-dependent behavior, achieving degree accuracy in real time. The reconstruction algorithms in TA imaging are also discussed, including a proposed forward reconstruction algorithm which bypasses the ill-posed inverse problem by correlating the measured signals with pre-calculated point spread functions in an iterative manner.
Book Synopsis Auditory Effects of Microwave Radiation by : James C. Lin
Download or read book Auditory Effects of Microwave Radiation written by James C. Lin and published by Springer Nature. This book was released on 2021-08-19 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the human auditory effects of exposure to directed beams of high-power microwave pulses, which research results have shown can cause a cascade of health events when aimed at a human subject or the subject’s head. The book details multidisciplinary investigations using physical theories and models, physiological events and phenomena, and computer analysis and simulation. Coverage includes brain anatomy and physiology, dosimetry of microwave power deposition, microwave auditory effect, interaction mechanisms, shock/pressure wave induction, Havana syndrome, and application in microwave thermoacoustic tomography (MTT). The book will be welcomed by scientists, academics, health professionals, government officials, and practicing biomedical engineers as an important contribution to the continuing study of the effects of microwave pulse absorption on humans.
Book Synopsis Molecular Imaging by : Ralph Weissleder
Download or read book Molecular Imaging written by Ralph Weissleder and published by PMPH-USA. This book was released on 2010 with total page 1384 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of molecular imaging of living subjects have evolved considerably and have seen spectacular advances in chemistry, engineering and biomedical applications. This textbook was designed to fill the need for an authoritative source for this multi-disciplinary field. We have been fortunate to recruit over 80 leading authors contributing 75 individual chapters. Given the multidisciplinary nature of the field, the book is broken into six different sections: "Molecular Imaging technologies", "Chemistry", "Molecular Imaging in Cell and Molecular Biology", "Applications of Molecular Imaging", "Molecular Imaging in Drug Evaluation" with the final section comprised of chapters on computation, bioinformatics and modeling. The organization of this large amount of information is logical and strives to avoid redundancies among chapters. It encourages the use of figures to illustrate concepts and to provide numerous molecular imaging examples.
Book Synopsis Microwave-induced Thermoacoustic Tomography by : Dazi Feng
Download or read book Microwave-induced Thermoacoustic Tomography written by Dazi Feng and published by . This book was released on 2001 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Electronically Focused Two-dimensional Acoustic Imaging System by : Stanford University. Microwave Laboratory
Download or read book Electronically Focused Two-dimensional Acoustic Imaging System written by Stanford University. Microwave Laboratory and published by . This book was released on 1975 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advances in Molecular Biophotonics by : Yong Deng
Download or read book Advances in Molecular Biophotonics written by Yong Deng and published by Walter de Gruyter GmbH & Co KG. This book was released on 2017-04-24 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Being the most active field in modern physics, Optical Physics has developed many new branches and interdisciplinary fields overlapping with various classical disciplines. This series summarizes the advancements of optical physics in the past twenty years in the following fields: High Field Laser Physics, Precision Laser Spectroscopy, Nonlinear Optics, Nanophotonics, Quantum Optics, Ultrafast Optics, Condensed Matter Optics, and Molecular Biophotonics.
Book Synopsis Advances in Acoustic Microscopy and High Resolution Imaging by : Roman Gr. Maev
Download or read book Advances in Acoustic Microscopy and High Resolution Imaging written by Roman Gr. Maev and published by John Wiley & Sons. This book was released on 2013-02-04 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Novel physical solutions, including new results in the field of adaptive methods and inventive approaches to inverse problems, original concepts based on high harmonic imaging algorithms, intriguing vibro-acoustic imaging and vibro-modulation technique, etc. were successfully introduced and verified in numerous studies of industrial materials and biomaterials in the last few years. Together with the above mentioned traditional academic and practical avenues in ultrasonic imaging research, intriguing scientific discussions have recently surfaced and will hopefully continue to bear fruits in the future. The goal of this book is to provide an overview of the recent advances in high-resolution ultrasonic imaging techniques and their applications to biomaterials evaluation and industrial materials. The result is a unique collection of papers presenting novel results and techniques that were developed by leading research groups worldwide. This book offers a number of new results from well-known authors who are engaged in aspects of the development of novel physical principles, new methods, or implementation of modern technological solutions into current imaging devices and new applications of high-resolution imaging systems. The ultimate purpose of this book is to encourage more research and development in the field to realize the great potential of high resolution acoustic imaging and its various industrial and biomedical applications.
Book Synopsis Functional Imaging of Early Markers of Disease by : N. Simpson
Download or read book Functional Imaging of Early Markers of Disease written by N. Simpson and published by IOS Press. This book was released on 2004 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second part which highlights the role that various imaging techniques play and/or might be able to play in detecting markers of disease. Cancer is often used as the example disease, but tumors exhibit many properties in common with other tissue, so it is possible to see how the techniques could be used in the diagnosis and management of other disease. There are also examples of the reverse of this flow of hypothesis and knowledge from one discipline to another. Magnetic resonance spectroscopy can be used to detect the chemical milieu of the nucleus being focused on, be it phosphorus-31 (Arias-Mendoza) or protons (He). Phosphorus is intimately involved in carbohydrate, phospholipid metabolism and energy transfer. The brain has been the testing ground for ideas in MRI and MRS; it continues to be so today, with extension to tumor diagnosis as insights are reached and assimilated. This issue contains three techniques that rely solely or partially on optical characteristics of tissue. The supplement, in 2 issues, has mostly emphasized possibilities rather than clinically available techniques.The final chapter attempts to draw together the modalities of medical imaging and push the frontiers yet further to show how imaging and markers can be used together in the screening, diagnosis, and management of patients' disease.
Book Synopsis Photoacoustic and Thermoacoustic Tomography by : Geng Ku
Download or read book Photoacoustic and Thermoacoustic Tomography written by Geng Ku and published by . This book was released on 2006 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Photoacoustic tomography (PAT), as well as thermoacoustic tomography (TAT), utilize electromagnetic radiation in its visible, near infrared, microwave, and radiofrequency forms, respectively, to induce acoustic waves in biological tissues for imaging purposes. Combining the advantages of both the high image contrast that results from electromagnetic absorption and the high resolution of ultrasound imaging, these new imaging modalities could be the next successful imaging techniques in biomedical applications. Basic research on PAT and TAT, and the relevant physics, is presented in Chapter I. In Chapter II, we investigate the imaging mechanisms of TAT in terms of signal generation, propagation and detection. We present a theoretical analysis as well as simulations of such imaging characteristics as contrast and resolution, accompanied by experimental results from phantom and tissue samples. In Chapter III, we discuss the further application of TAT to the imaging of biological tissues. The microwave absorption difference in normal and cancerous breast tissues, as well as its influence on thermoacoustic wave generation and the resulting transducer response, is investigated over a wide range of electromagnetic frequencies and depths of tumor locations. In Chapter IV, we describe the mechanism of PAT and the algorithm used for image reconstruction. Because of the broad bandwidth of the laser-induced ultrasonic waves and the limited bandwidth of the single transducer, multiple ultrasonic transducers, each with a different central frequency, are employed for simultaneous detection. Chapter V further demonstrates PAT's ability to image vascular structures in biological tissue based on blood's strong light absorption capability. The photoacoustic images of rat brain tumors in this study clearly reveal the angiogenesis that is associated with tumors. In ChapterVI, we report on further developing PAT to image deeply embedded optical heterogeneity in biological tissues. The improved imaging ability is attributed to better penetration by NIR light, the use of the optical contrast agent ICG (indocyanine green) and a new detection scheme of a circular scanning configuration. Deep penetrating PAT, which is based on a tissue's intrinsic contrast using laser light of 532um [mu] green light and1.06 um [mu] near infrared light, is also presented.
Book Synopsis Diseases of the Breast by : Jay R. Harris
Download or read book Diseases of the Breast written by Jay R. Harris and published by Lippincott Williams & Wilkins. This book was released on 2012-03-28 with total page 3432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, and now in full color throughout, the Fourth Edition of this definitive reference is a must for all clinicians who treat breast diseases. Leading experts summarize the current knowledge of breast diseases, including their clinical features, management, underlying biologies, and epidemiologies. In addition to complete coverage of malignant breast diseases, benign diseases are discussed in relation to subsequent breast cancer development. The book reviews all major clinical trials and summarizes the information they provide on early detection and management of breast cancer. Close attention is also given to the increasing importance of molecular biology and genetics in this field. This edition features more than thirty new contributors, fourteen new or completely rewritten chapters, and more clinically oriented chapters. A companion Website will offer the fully searchable text and an image bank. Also included with this edition is the Anatomical Chart Company's Breast Anatomy and Disorders Pocket Guide. This durable, portable folding pocket guide provides a visual and textual overview of breast anatomy, disorders, and breast self-examination. With a write-on, wipe-off laminated surface, this guide is perfect for the on-the-go practitioner to show patients, caregivers, and families.
