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Scanning Electron Microscopy Of Cerebellar Cortex
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Book Synopsis Scanning Electron Microscopy of Cerebellar Cortex by : Orlando Castejón
Download or read book Scanning Electron Microscopy of Cerebellar Cortex written by Orlando Castejón and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a clear exposition this inspirational book shows the in situ three-dimensional morphology of cerebellar neurons, intracortical circuits and synaptic connections that underpin the functioning of cerebellar neurons in networks. It brings together in one volume a new view of the three-dimensional cytoarchitectonic arrangement of the cerebellar cortex. The book shows the cerebellar extrinsic and intrinsic intracortical circuits formed by mossy and climbing fibers as exposed by the cryofracture methods. The high degree of lateral collateralization of these fibers is also displayed providing new insights on the information processing in the cerebellar cortex. Besides, field emission high resolution electron microscopy shows its potential contribution to the study of synaptic morphology. The concluding chapter deals with the contribution of scanning electron microscopy to cerebellar neurobiology. This monograph is an authoritative survey and a must for anyone who is interested in the structure of the central nervous system. It will also appeal to an interdisciplinary audience who wants to learn more about electron microscopy and neurocytology.
Download or read book Cerebellar Cortex written by S.L. Palay and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: The origins of this book go back to the first electron microscopic studies of the central nervous system. The cerebellar cortex was from the first an object of close study in the electron microscope, repeating in modern cytology and neuroanatomy the role it had in the hands of RAMON y CAJAL at the end of the nineteenth century. The senior author vividly remembers a day early in 1953 when GEORGE PALADE, with whom he was then working, showed him an electron micrograph of a cerebellar glomerulus, saying "That is what the synapse should look like. " It is true that the tissue was swollen and the mitochondria were exploded, but all of the essentials of synaptic structure were visible. At that time small fragments of tissue, fixed by immersion in osmium tetroxide and embedded in methacrylate, were laboriously sectioned with glass knives without any predetermined orientation and then examined in the electron microscope. After much searching, favorably preserved areas' were studied at the cytological level in order to recognize the parts of neurons and characterize them. Such procedures, dependent upon random sections and uncontrollable selection by a highly erratic technique of preservation, precluded any systematic investigation of the organization of a particular nucleus or region of the central nervous system. It was difficult enough to distinguish neurons from the neuroglia.
Book Synopsis Scanning Electron Microscopy by : Om Johari
Download or read book Scanning Electron Microscopy written by Om Johari and published by Scanning Microscopy International. This book was released on 1978-12 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1968-77 include the proceedings of the annual Scanning Electron Microscope Symposium, sponsored by the IIT Research Institute, and other workshops.
Book Synopsis Scanning Electron Microscopy for the Life Sciences by : Heide Schatten
Download or read book Scanning Electron Microscopy for the Life Sciences written by Heide Schatten and published by Cambridge University Press. This book was released on 2013 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to modern scanning electron microscopy instrumentation, methodology and techniques, highlighting novel applications to cell and molecular biology.
Download or read book Scanning Electron Microscopy written by and published by . This book was released on 1985 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1968-77 include the proceedings of the annual Scanning Electron Microscope Symposium, sponsored by the IIT Research Institute, and other workshops.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1808 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Scanning Microscopy written by and published by . This book was released on 1993 with total page 1400 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Cerebral Veins written by L.M. Auer and published by Springer Science & Business Media. This book was released on 2013-12-11 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research in the morphology-angioarchitecture and ultrastructure-of cerebral veins has been widely neglected in past decades; investigation was mainly focussed on the arterial side of brain circulation. This circumstance has certainly had a negative impact on the development of knowledge in clinical medicine about cerebral venous disease. Cerebra} venous pathology and its consequence is, however, a frequent problern in clinical neurosur gery, both with regard to operative techniques and conservative manage ment. Therefore, it is not surprising that the initiative to collect, for the first time, data on our present knowledge in basic research of cerebral veins, their structure and function under normal and pathological circumstances, came from clinicians. Regarding the cerebral veins the clinician has primarily in view the dysfunctions originating from embryogenetic malformations, phlebitic obstruction, tumourous shunts, or traumatic lesions. But in addition to that, particular attention should be paid to the microstructure ofthe venous vessel walls, their barrier function, and the venous vasomotor system. Studying these interrelationships has for a long time been both fascinating and of immediate interest to me.
Book Synopsis Handbook of the Cerebellum and Cerebellar Disorders by : Mario Manto
Download or read book Handbook of the Cerebellum and Cerebellar Disorders written by Mario Manto and published by Springer. This book was released on 2012-08-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our knowledge of cerebellar functions and cerebellar disorders, called ataxias, is increasing considerably. Studies of the cerebellum are now a central focus in neuroscience. During the last four decades, many laboratories worldwide have dedicated their research activities to understanding the roles of the cerebellum in motor control, cognitive processes and biology of mental processes, behavioral symptoms, and emotion. It is now accepted that the cerebellum acts as a cognitive operator in learning, perception, and attention. Moreover, major improvements in our assessment of in vivo cerebellar architecture using imaging techniques have occurred. A typical example is the accurate description of cerebellar anatomy during fetal development with MRI, a progress which has direct impacts on patient care. These advances have been associated with discoveries of new clinical disorders, in particular in the field of genetic ataxias. More than 20 new genes have been identified these last 10 years. Only for dominant ataxias, more than 30 diseases have now been unravelled. The number of ataxic disorders will increase with aging, the cerebellum being the structure of the brain with the most important loss of neurons with age. More than 300 different cerebellar disorders are encountered during daily practice, but we are missing a single source of information explaining their pathogenesis. Despite the immense amount of knowledge acquired about the cerebellar circuitry these last years, a large book covering the neuroscience of the cerebellum is missing. The goal of this endeavour is to bring up to date information relevant for basic science and also for clinical activities. To reach this goal, the most renowned authors are gathered in a unique and in-depth book with a format of a handbook. We emphasize the connections between molecular findings, imaging features, behavioural/neuropsychological aspects, and clinical implications.
Book Synopsis Rebuilding cerebellar network computations from cellular neurophysiology by : Egidio D'Angelo
Download or read book Rebuilding cerebellar network computations from cellular neurophysiology written by Egidio D'Angelo and published by Frontiers E-books. This book was released on with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic is centered around the attempt to understand network activity of the brain by combining experimental and modeling techniques. A surprisingly rich set of new observations is emerging about the functions of the olivo-cerebellar cortical modules. This Research Topic will consider the critical elements of new emerging knowledge achieved using in vitro and in vivo techniques and the computational attempts at functional circuit reconstruction.
Book Synopsis Biological Field Emission Scanning Electron Microscopy, 2 Volume Set by : Roland A. Fleck
Download or read book Biological Field Emission Scanning Electron Microscopy, 2 Volume Set written by Roland A. Fleck and published by John Wiley & Sons. This book was released on 2019-04-29 with total page 741 pages. Available in PDF, EPUB and Kindle. Book excerpt: The go‐to resource for microscopists on biological applications of field emission gun scanning electron microscopy (FEGSEM) The evolution of scanning electron microscopy technologies and capability over the past few years has revolutionized the biological imaging capabilities of the microscope—giving it the capability to examine surface structures of cellular membranes to reveal the organization of individual proteins across a membrane bilayer and the arrangement of cell cytoskeleton at a nm scale. Most notable are their improvements for field emission scanning electron microscopy (FEGSEM), which when combined with cryo-preparation techniques, has provided insight into a wide range of biological questions including the functionality of bacteria and viruses. This full-colour, must-have book for microscopists traces the development of the biological field emission scanning electron microscopy (FEGSEM) and highlights its current value in biological research as well as its future worth. Biological Field Emission Scanning Electron Microscopy highlights the present capability of the technique and informs the wider biological science community of its application in basic biological research. Starting with the theory and history of FEGSEM, the book offers chapters covering: operation (strengths and weakness, sample selection, handling, limitations, and preparation); Commercial developments and principals from the major FEGSEM manufacturers (Thermo Scientific, JEOL, HITACHI, ZEISS, Tescan); technical developments essential to bioFEGSEM; cryobio FEGSEM; cryo-FIB; FEGSEM digital-tomography; array tomography; public health research; mammalian cells and tissues; digital challenges (image collection, storage, and automated data analysis); and more. Examines the creation of the biological field emission gun scanning electron microscopy (FEGSEM) and discusses its benefits to the biological research community and future value Provides insight into the design and development philosophy behind current instrument manufacturers Covers sample handling, applications, and key supporting techniques Focuses on the biological applications of field emission gun scanning electron microscopy (FEGSEM), covering both plant and animal research Presented in full colour An important part of the Wiley-Royal Microscopical Series, Biological Field Emission Scanning Electron Microscopy is an ideal general resource for experienced academic and industrial users of electron microscopy—specifically, those with a need to understand the application, limitations, and strengths of FEGSEM.
Book Synopsis Imaging Synapse Structure and Function by : George J. Augustine
Download or read book Imaging Synapse Structure and Function written by George J. Augustine and published by Frontiers Media SA. This book was released on 2017-07-06 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development of new imaging technologies in recent years has transformed neuroscience in profound ways. Following on the heels of the revolution based on the Green Fluorescent Protein, refined genetically-encoded fluorescent reporters and genetic targeting strategies now enable optical recording of synaptic transmission in defined neuronal populations at speeds approaching the enviable temporal resolution of electrophysiology. Super-resolution light microscopy permits observation of synapses and their molecular machinery at sub-diffraction resolution. At the ultrastructural level, automated forms of electron microscopy, improvements in specimen fixation methods, and recent efforts to correlate data from light and electron micrographs now make the reconstruction of functional neural circuits a reality. Finally, the use of optogenetic actuators, such as channelrhodopsins, allows precise temporal and spatial manipulation of neuronal activity and is revealing profound insights into the organization of neural circuits and their roles in behavior. This research topic highlights recent advances in both light and electron microscopy, with a specific focus on approaches that combine innovations from several different fields to obtain novel information about synapse structure and function. We are confident that this collection of articles - three original research papers, six reviews, one methods paper and one perspective article - will enable neuroscientists to achieve the next generation of experiments aimed at cracking the neural code.
Book Synopsis Developmental Neurobiology by : Marcus Jacobson
Download or read book Developmental Neurobiology written by Marcus Jacobson and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 782 pages. Available in PDF, EPUB and Kindle. Book excerpt: This consistent and well-illustrated text is an up-to-date survey of cellular and molecular events contributing to the assembly of the vertebrate nervous system. Chapters include a mixture of historical content and descriptions from literature that best illustrate specific aspects of development.
Book Synopsis Proceedings, ... Annual Meeting, Electron Microscopy Society of America by : Electron Microscopy Society of America. Meeting
Download or read book Proceedings, ... Annual Meeting, Electron Microscopy Society of America written by Electron Microscopy Society of America. Meeting and published by . This book was released on 1990 with total page 1016 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Emerging Mechanisms in Dynamic GABAergic Inhibition by : Shiva K. Tyagarajan
Download or read book Emerging Mechanisms in Dynamic GABAergic Inhibition written by Shiva K. Tyagarajan and published by Frontiers Media SA. This book was released on 2021-12-01 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Human Nervous System by : Juergen K Mai
Download or read book The Human Nervous System written by Juergen K Mai and published by Academic Press. This book was released on 2011-12-13 with total page 1429 pages. Available in PDF, EPUB and Kindle. Book excerpt: The previous two editions of the Human Nervous System have been the standard reference for the anatomy of the central and peripheral nervous system of the human. The work has attracted nearly 2,000 citations, demonstrating that it has a major influence in the field of neuroscience. The 3e is a complete and updated revision, with new chapters covering genes and anatomy, gene expression studies, and glia cells. The book continues to be an excellent companion to the Atlas of the Human Brain, and a common nomenclature throughout the book is enforced. Physiological data, functional concepts, and correlates to the neuroanatomy of the major model systems (rat and mouse) as well as brain function round out the new edition. Adopts standard nomenclature following the new scheme by Paxinos, Watson, and Puelles and aligned with the Mai et al. Atlas of the Human Brain (new edition in 2007) Full color throughout with many new and significantly enhanced illustrations Provides essential reference information for users in conjunction with brain atlases for the identification of brain structures, the connectivity between different areas, and to evaluate data collected in anatomical, physiological, pharmacological, behavioral, and imaging studies
Book Synopsis The Science of Biological Specimen Preparation for Microscopy by : Godfried M. Roomans
Download or read book The Science of Biological Specimen Preparation for Microscopy written by Godfried M. Roomans and published by . This book was released on 1996 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt:
