Role Of Sulfation Pharmacogenetics In Breast Cancer Treatment With 2 Methoxyestradiol

Download Role Of Sulfation Pharmacogenetics In Breast Cancer Treatment With 2 Methoxyestradiol full books in PDF, epub, and Kindle. Read online Role Of Sulfation Pharmacogenetics In Breast Cancer Treatment With 2 Methoxyestradiol ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Dosage Form Design Considerations

Author :
Publisher : Academic Press
ISBN 13 : 0128144246
Total Pages : 881 pages
Book Rating : 4.1/5 (281 download)

DOWNLOAD NOW!

Book Synopsis Dosage Form Design Considerations by :

Download or read book Dosage Form Design Considerations written by and published by Academic Press. This book was released on 2018-07-28 with total page 881 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dosage Form Design Parameters, Volume I, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries. - Examines the history and recent developments in drug dosage forms for pharmaceutical sciences - Focuses on physicochemical aspects, prefomulation solid state properties and polymorphism - Contains extensive references for further discovery and learning that are appropriate for advanced undergraduates, graduate students and those interested in drug dosage design

Handbook of Dietary Phytochemicals

Author : Jianbo Xiao
Publisher : Springer
ISBN 13 : 9789811541476
Total Pages : 1953 pages
Book Rating : 4.5/5 (414 download)

DOWNLOAD NOW!

Book Synopsis Handbook of Dietary Phytochemicals by : Jianbo Xiao

Download or read book Handbook of Dietary Phytochemicals written by Jianbo Xiao and published by Springer. This book was released on 2021-09-02 with total page 1953 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes recent advances in the chemistry, bioactivity, nutrition, and functional aspects of dietary phytochemicals, as well as the health and functional aspects of foods rich in phytochemicals. Consisting of forty-four chapters, it discusses the different chemical types of phytochemicals in our diets and food and presents data collected from animal or human experiments that are directly related to human health. Each chapter covers the chemistry, epidemiological study, bioavailability, bioactivity (animal experiments) function in humans and safety, as well as products on the market. Moreover, the more than 200 figures make it easy to grasp the main findings in each area.

Chemical Biology

Author : Jonathan E. Hempel
Publisher : Humana
ISBN 13 : 9781493922680
Total Pages : 0 pages
Book Rating : 4.9/5 (226 download)

DOWNLOAD NOW!

Book Synopsis Chemical Biology by : Jonathan E. Hempel

Download or read book Chemical Biology written by Jonathan E. Hempel and published by Humana. This book was released on 2015-01-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume seeks to enable the discovery of tools in chemical biology by providing readers with various techniques ranging from initial chemical genetic screening to target identification. To successfully highlight the essential components of the chemical biology tool discovery process, the book is organizes into four parts that focus on platforms for molecular discovery in in vitro cellular systems, in vivo chemical genetic screening protocols, and methods used to discover functional protein targets. Written in the highly successful Methods of Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Practical and informative, Chemical Biology: Methods and Protocols seeks to improve the success rate of the chemical biology field through the dissemination of detailed and experiential knowledge.

Drug-like Properties: Concepts, Structure Design and Methods

Author : Li Di
Publisher : Elsevier
ISBN 13 : 0080557619
Total Pages : 549 pages
Book Rating : 4.0/5 (85 download)

DOWNLOAD NOW!

Book Synopsis Drug-like Properties: Concepts, Structure Design and Methods by : Li Di

Download or read book Drug-like Properties: Concepts, Structure Design and Methods written by Li Di and published by Elsevier. This book was released on 2010-07-26 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasing importance in advancing high quality candidates to clinical studies and the processes of drug discovery. If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process. The authors describe how properties affect in vivo pharmacological activity and impact in vitro assays. Individual drug-like properties are discussed from a practical point of view, such as solubility, permeability and metabolic stability, with regard to fundamental understanding, applications of property data in drug discovery and examples of structural modifications that have achieved improved property performance. The authors also review various methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties. - Serves as an essential working handbook aimed at scientists and students in medicinal chemistry - Provides practical, step-by-step guidance on property fundamentals, effects, structure-property relationships, and structure modification strategies - Discusses improvements in pharmacokinetics from a practical chemist's standpoint

Dosage Form Design Parameters

Author :
Publisher : Academic Press
ISBN 13 : 012814422X
Total Pages : 816 pages
Book Rating : 4.1/5 (281 download)

DOWNLOAD NOW!

Book Synopsis Dosage Form Design Parameters by :

Download or read book Dosage Form Design Parameters written by and published by Academic Press. This book was released on 2018-07-25 with total page 816 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dosage Form Design Parameters, Volume II, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries. - Examines the history and recent developments in drug dosage forms for pharmaceutical sciences - Focuses on physicochemical aspects, prefomulation solid state properties and polymorphism - Contains extensive references for further discovery and learning that are appropriate for advanced undergraduates, graduate students and those interested in drug dosage design

Alphaherpesviruses

Author : Sandra Knowles Weller
Publisher : Caister Academic Press Limited
ISBN 13 : 9781904455769
Total Pages : 0 pages
Book Rating : 4.4/5 (557 download)

DOWNLOAD NOW!

Book Synopsis Alphaherpesviruses by : Sandra Knowles Weller

Download or read book Alphaherpesviruses written by Sandra Knowles Weller and published by Caister Academic Press Limited. This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alphaherpesviruses are a fascinating group of DNA viruses that includes important human pathogens such as herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV): the causative agents of cold sores, genital ulcerous disease, and chickenpox/shingles, respectively. A key attribute of these viruses is their ability to establish lifelong latent infection in the peripheral nervous system of the host. Such persistence requires subversion of the host's immune system and intrinsic antiviral defense mechanisms. Understanding the mechanisms of the immune evasion and what triggers viral reactivation is a major challenge for today's researchers. This has prompted enormous research efforts into understanding the molecular and cellular biology of these viruses. This up-to-date and comprehensive volume aims to distill the most important research in this area providing a timely overview of the field. Topics covered include: transcriptional regulation, DNA replication, translational control, virus entry and capsid assembly, the role of microRNAs in infection and oncolytic vectors for cancer therapy. In addition there is coverage of virus-host interactions, including apoptosis, subversion of host protein quality control and DNA damage response pathways, autophagy, establishment and reactivation from latency, interferon responses, immunity and vaccine development. Essential reading for everyone working with alphaherpesviruses and of interest to all virologists working on latent infections.

Primary Prevention and Cancer

Author : Willy J. Eylenbosch
Publisher : Springer
ISBN 13 : 9783540537045
Total Pages : 130 pages
Book Rating : 4.5/5 (37 download)

DOWNLOAD NOW!

Book Synopsis Primary Prevention and Cancer by : Willy J. Eylenbosch

Download or read book Primary Prevention and Cancer written by Willy J. Eylenbosch and published by Springer. This book was released on 1991-08-09 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading scientists discuss in this book how we can not only detect cancer at an early stage, but even work toward preventing it altogether in the future. They consider genetic and non-genetic causes of cancer, the development of new detection methods, as well as other factors that will improve our understanding of the basic mechanisms of carcinogenesis.

Handbook of Pediatric Transfusion Medicine

Author : Christopher D. Hillyer
Publisher : Elsevier
ISBN 13 : 008049143X
Total Pages : 415 pages
Book Rating : 4.0/5 (84 download)

DOWNLOAD NOW!

Book Synopsis Handbook of Pediatric Transfusion Medicine by : Christopher D. Hillyer

Download or read book Handbook of Pediatric Transfusion Medicine written by Christopher D. Hillyer and published by Elsevier. This book was released on 2004-02-23 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structured to be a companion to the recently published Handbook of Transfusion Medicine, the Handbook of Pediatric Transfusion Medicine is dedicated to pediatric hematology-oncology and transfusion medicine, a field which remains ambiguous and which has generated few comprehensive texts. This book stands alone as one of the few texts that addresses transfusion issues specific to pediatric medicine. Written in an eminently readable style, this authoritative handbook is a requirement for any pediatric physician or caregiver. - Neonatal and fetal immune response and in utero development issues - Blood compatability and pre-transfusion testing issues specific to pediatric and neonatal transfusion - Therapeutic apheresis including red blood cell exchange and prophylactic chronic erythrocytapheresis for sickle cell patients - Also includes a section that concentrates on the consent, quality and legal issues of blood transfusion and donation

Computational Phytochemistry

Author : Satyajit Dey Sarker
Publisher : Elsevier
ISBN 13 : 0443161038
Total Pages : 532 pages
Book Rating : 4.4/5 (431 download)

DOWNLOAD NOW!

Book Synopsis Computational Phytochemistry by : Satyajit Dey Sarker

Download or read book Computational Phytochemistry written by Satyajit Dey Sarker and published by Elsevier. This book was released on 2024-03-06 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Phytochemistry, Second Edition, explores how recent advances in computational techniques and methods have been embraced by phytochemical researchers to enhance many of their operations, refocusing and expanding the possibilities of phytochemical studies. By applying computational aids and mathematical models to extraction, isolation, structure determination, and bioactivity testing, researchers can obtain highly detailed information about phytochemicals and optimize working approaches. This book aims to support and encourage researchers currently working with or looking to incorporate computational methods into their phytochemical work. Topics in this book include computational methods for predicting medicinal properties, optimizing extraction, isolating plant secondary metabolites, and building dereplicated phytochemical libraries. The roles of high-throughput screening, spectral data for structural prediction, plant metabolomics, and biosynthesis are all reviewed before the application of computational aids for assessing bioactivities and virtual screening is discussed. Illustrated with detailed figures and supported by practical examples, this book is an indispensable guide for all those involved with the identification, extraction, and application of active agents from natural products. This new edition captures remarkable advancements in mathematical modeling and computational methods that have been incorporated in phytochemical research, addressing, e.g., extraction, isolation, structure determination, and bioactivity testing of phytochemicals. - Includes step-by-step protocols for various computational and mathematical approaches applied to phytochemical research - Features clearly illustrated chapters contributed by highly reputable researchers - Covers all key areas in phytochemical research, including virtual screening and metabolomics

Turmeric

Author : P. N. Ravindran
Publisher : CRC Press
ISBN 13 : 1420006320
Total Pages : 506 pages
Book Rating : 4.4/5 (2 download)

DOWNLOAD NOW!

Book Synopsis Turmeric by : P. N. Ravindran

Download or read book Turmeric written by P. N. Ravindran and published by CRC Press. This book was released on 2007-03-01 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the last 6000 years turmeric has been used in Ayurvedic medicine to alleviate pain, balance digestion, purify body and mind, clear skin diseases, expel phlegm, and invigorate the blood. Nowadays, this plant has acquired great importance with its anti-aging, anti-cancer, anti-Altzheimer, antioxidant, and a variety of other medicinal properties.

Cadmium in the Human Environment

Author : Gunnar Nordberg
Publisher :
ISBN 13 :
Total Pages : 500 pages
Book Rating : 4.:/5 (318 download)

DOWNLOAD NOW!

Book Synopsis Cadmium in the Human Environment by : Gunnar Nordberg

Download or read book Cadmium in the Human Environment written by Gunnar Nordberg and published by . This book was released on 1992 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cadmium is widely dispersed in the environment. Human exposure to low levels occur as a result of natural processes as well as human activities such as mining, smelting, fossil fuel combustion and industrial use. Pollution of the general environment by cadmium has as yet only been related to the development of human disease in some special situations, such as itai-itai disease and renal dysfunction in Belgium and in China. However, the possibility of more widespread contamination and greater mobility of cadmium in the environment on the one hand and the advent of new data concerning the carcinogenicity of cadmium on the other, make this review of the "state of the art" in human risk identification and assessment timely. Recent studies on human exposure to cadmium metabolism and toxicology, renal dysfunction and related effects, and experimental and epidemiological evidence for carcinogenicity of cadmium are described.

Chemistry for Pharmacy Students

Author : Professor Satyajit D. Sarker
Publisher : John Wiley & Sons
ISBN 13 : 1118687531
Total Pages : 397 pages
Book Rating : 4.1/5 (186 download)

DOWNLOAD NOW!

Book Synopsis Chemistry for Pharmacy Students by : Professor Satyajit D. Sarker

Download or read book Chemistry for Pharmacy Students written by Professor Satyajit D. Sarker and published by John Wiley & Sons. This book was released on 2013-05-28 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book has succeeded in covering the basic chemistry essentials required by the pharmaceutical science student... the undergraduate reader, be they chemist, biologist or pharmacist will find this an interesting and valuable read." –Journal of Chemical Biology, May 2009 Chemistry for Pharmacy Students is a student-friendly introduction to the key areas of chemistry required by all pharmacy and pharmaceutical science students. The book provides a comprehensive overview of the various areas of general, organic and natural products chemistry (in relation to drug molecules). Clearly structured to enhance student understanding, the book is divided into six clear sections. The book opens with an overview of general aspects of chemistry and their importance to modern life, with particular emphasis on medicinal applications. The text then moves on to a discussion of the concepts of atomic structure and bonding and the fundamentals of stereochemistry and their significance to pharmacy- in relation to drug action and toxicity. Various aspects of aliphatic, aromatic and heterocyclic chemistry and their pharmaceutical importance are then covered with final chapters looking at organic reactions and their applications to drug discovery and development and natural products chemistry. accessible introduction to the key areas of chemistry required for all pharmacy degree courses student-friendly and written at a level suitable for non-chemistry students includes learning objectives at the beginning of each chapter focuses on the physical properties and actions of drug molecules

Mass Spectra and GC Data of Steroids

Author : Hugh L. J. Makin
Publisher : Wiley-VCH
ISBN 13 :
Total Pages : 592 pages
Book Rating : 4.F/5 ( download)

DOWNLOAD NOW!

Book Synopsis Mass Spectra and GC Data of Steroids by : Hugh L. J. Makin

Download or read book Mass Spectra and GC Data of Steroids written by Hugh L. J. Makin and published by Wiley-VCH. This book was released on 1998 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the most comprehensive collection of mass spectral data for steroids available today. It contains some 2,500 newly measured EI(+) mass spectra of androgens and estrogens and their derivatives (trimethylsilyl ethers, O-methyloximes and acetates). Each spectrum is accompanied by the structure, systematic and trivial names, retention index, molecular formula, molar mass, CAS number and sample source of the steroid, with all data obtained using the same mass spectrometer under identical chromatographic and mass spectrometric conditions. Steroids are of considerable therapeutic importance, and the collection will thus be of particular interest to the pharmaceutical industry, as well as an invaluable data source for chemists and biochemists involved in drug development, drug screening and clinical toxicology, endocrinologists, natural products chemists and mass spectroscopists

Hematologic Malignancies in Adults

Author : MiKaela M. Olsen
Publisher :
ISBN 13 : 9781935864264
Total Pages : 0 pages
Book Rating : 4.8/5 (642 download)

DOWNLOAD NOW!

Book Synopsis Hematologic Malignancies in Adults by : MiKaela M. Olsen

Download or read book Hematologic Malignancies in Adults written by MiKaela M. Olsen and published by . This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than 180 years since Thomas Hodgkin identified the first hematologic malignancy, nurses are still learning the best ways to treat patients with these complex cancers. Hematologic Malignancies in Adults gives you comprehensive information on treatments, complications, and toxicity management for your everyday practice. The book focuses on the management of disease-related manifestations and treatment-related side effects and toxicities. You'll find details on forms of hematologic malignancies, including leukemia and lymphoma, Hodgkin lymphoma, mature T-cell and NK-cell neoplasms, and multiple myeloma. Also included is a chapter on vascular access and a listing of drugs used in the treatment of hematologic malignancies. The management of patients with myeloid and lymphoid neoplasms is unique, complex, and vital to ensuring successful outcomes and improved quality of life. This book gives you every tool you need to keep pace with the advances in medicine and science as you trea

The Sex Steroids

Author : Kenneth W. McKerns
Publisher : Appleton-Century-Crofts
ISBN 13 :
Total Pages : 472 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!

Book Synopsis The Sex Steroids by : Kenneth W. McKerns

Download or read book The Sex Steroids written by Kenneth W. McKerns and published by Appleton-Century-Crofts. This book was released on 1971 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Otterness

Author : Tom Otterness
Publisher :
ISBN 13 :
Total Pages : 80 pages
Book Rating : 4.F/5 ( download)

DOWNLOAD NOW!

Book Synopsis Otterness by : Tom Otterness

Download or read book Otterness written by Tom Otterness and published by . This book was released on 1997 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1997

Iron Deficiency and Overload

Author : Shlomo Yehuda
Publisher : Springer Science & Business Media
ISBN 13 : 1597454621
Total Pages : 377 pages
Book Rating : 4.5/5 (974 download)

DOWNLOAD NOW!

Book Synopsis Iron Deficiency and Overload by : Shlomo Yehuda

Download or read book Iron Deficiency and Overload written by Shlomo Yehuda and published by Springer Science & Business Media. This book was released on 2010-03-10 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: Iron deficiency is ever-present among all populations throughout the world irrespective of race, culture, or ethnic background. Even with the latest advances in medicine, improved nutrition, and the ready availability of cheap oral iron, there is still no satisfactory explanation for the widespread occurrence of iron deficiency or for the absence of an effective treatment. Iron Deficiency and Overload: From Biology to Clinical Medicine is an important new text that provides a timely review of the latest science concerning iron metabolism as well as practical, data-driven options to manage at-risk populations with the best accepted therapeutic nutritional interventions. Chapter topics reflect the excitement in current theoretical development and laboratory activity in this area. The distinguished authors address their presentations to professionals and graduate students who need to be better informed about the concepts, methodologies, and current status of the field. Iron Deficiency and Overload: From Biology to Clinical Medicine is an essential text that presents a sampling of the major issues in iron research, from the most basic research level to human applications.