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Author : Pedro A Reche
Publisher : Frontiers Media SA
ISBN 13 : 2889633853
Total Pages : 139 pages
Book Rating : 4.8/5 (896 download)
Download or read book Reverse Vaccinology written by Pedro A Reche and published by Frontiers Media SA. This book was released on 2020-01-15 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Rino Rappuoli
Publisher : Caister Academic Press Limited
ISBN 13 : 9781904455745
Total Pages : 0 pages
Book Rating : 4.4/5 (557 download)
Download or read book Vaccine Design written by Rino Rappuoli and published by Caister Academic Press Limited. This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, expert international authors critically review the current cutting-edge research in vaccine design and development. Particular emphasis is given to new approaches and technologies.
Author : Jayashankar Das
Publisher : Elsevier
ISBN 13 : 0443133964
Total Pages : 383 pages
Book Rating : 4.4/5 (431 download)
Download or read book Reverse Vaccinology written by Jayashankar Das and published by Elsevier. This book was released on 2024-07-26 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reverse Vaccinology: Concept, Methods and Advancement presents the development strategy of new vaccines through genome sequencing bioinformatics analysis. Reverse vaccinology promises to revolutionize vaccine development, especially for pathogens to which the classical applications of Pasteur’s principles have failed, and it is explained in detail in this book.The book is split into three sections: the first, Concept, brings the basis of reverse vaccinology, vaccine antigen discovery, and subunit vaccine; the second, Tools and Methods, describes immunoinformatic, proteomics for epitope-vaccine design, data bases, network analysis, machine learning, and NGS driven antigen screening technology; and the last one, Disease Case Study, discusses real-world examples in the development of new vaccines for diverse diseases.It is a valuable resource for bioinformaticians, researchers, students, and member of the biomedical and medical fields who want to learn more about a new and agile process for the development of new vaccines. ? Explains the fundamentals of reverse vaccinology and how it can save time in the development of new vaccines ? Focuses on the efforts to develop a vaccine candidate against various pathogens using computational approaches ? Presents databases and web servers for conducting reverse vaccinology ? Describes the screening process of potential vaccine candidate through machine learning
Author : Darren R. Flower
Publisher : Springer Science & Business Media
ISBN 13 : 1461450705
Total Pages : 316 pages
Book Rating : 4.4/5 (614 download)
Download or read book Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines written by Darren R. Flower and published by Springer Science & Business Media. This book was released on 2012-12-09 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume will address an important emergent area within the field of immunomics: the discovery of antigens and adjuvants within the context of reverse vaccinology. Conventional approaches to vaccine design and development requires pathogens to be cultivated in the laboratory and the immunogenic molecules within them to be identifiable. Conventional vaccinology is no longer universally successful, particularly for recalcitrant pathogens. By using genomic information we can study vaccine development in silico: 'reverse vaccinology', can identify candidate subunits vaccines by identifying antigenic proteins and by using equally rational approaches to identify novel immune response-enhancing adjuvants.
Author : Fadil Bidmos
Publisher : Humana
ISBN 13 : 9781071619025
Total Pages : 0 pages
Book Rating : 4.6/5 (19 download)
Download or read book Bacterial Vaccines written by Fadil Bidmos and published by Humana. This book was released on 2022-12-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The importance of vaccines to combat bacterial diseases cannot be overstated. Methods used in the development and testing of these vaccines are evolving rapidly as a direct consequence of the availability of advanced technologies. This volume will cover methods developed in the last decade, the usage of which are enabling the development of cheaper, cost-effective and structurally stable vaccines for global use. Chapters cover in silico analytical methods such as reverse vaccinology and machine learning; low-energy electron irradiation for the generation of inactivated bacterial vaccines; methods for assessment of OMV/GMMA quality and stability; and controlled human infection models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Bacterial Vaccines: Methods and Protocols is a valuable resource for novice and expert researchers interested in learning more about this important and constantly evolving field.
Author : Joo Chuan Tong
Publisher : Elsevier
ISBN 13 : 1908818417
Total Pages : 164 pages
Book Rating : 4.9/5 (88 download)
Download or read book Computer-Aided Vaccine Design written by Joo Chuan Tong and published by Elsevier. This book was released on 2013-07-31 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational pre-screening of antigens is now routinely applied to the discovery of vaccine candidates.Computer-aided vaccine design is a comprehensive introduction to this exciting field of study. The book is intended to be a textbook for researchers and for courses in bioinformatics, as well as a laboratory reference guide. It is written mainly for biologists who want to understand the current methods of computer-aided vaccine design. The contents are designed to help biologists appreciate the underlying concepts and algorithms used, as well as limitations of the methods and strategies for their use. Chapters include: MHC and T cell responses; Immunoglobulins and B cell responses; Scientific publications and databases; Database design; Computational T cell vaccine design; Computational B cell vaccine design; infectious disease informatics; Vaccine safety and quality assessments; and Vaccine adjuvant informatics. - Essential reading for any biologist who wants to understand methods of computer-aided vaccine design - Description of available data sources and publicly available software, with detailed analysis of strengths and weaknesses - Theoretical concepts and practical examples of database design and development for a virtual screening campaign
Author : Barry R. Bloom
Publisher : Academic Press
ISBN 13 : 012805400X
Total Pages : 666 pages
Book Rating : 4.1/5 (28 download)
Download or read book The Vaccine Book written by Barry R. Bloom and published by Academic Press. This book was released on 2016-06-23 with total page 666 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child's risk. - Provides insights into diseases that could be prevented, along with the challenges facing research scientists in the world of vaccines - Gives new ideas about future vaccines and concepts - Introduces new vaccines and concepts - Gives ideas about challenges facing public and private industrial investors in the vaccine area - Discusses the problem of declining immunization rates and vaccine hesitancy
Author : Matthias Giese
Publisher : Springer
ISBN 13 : 331925832X
Total Pages : 383 pages
Book Rating : 4.3/5 (192 download)
Download or read book Introduction to Molecular Vaccinology written by Matthias Giese and published by Springer. This book was released on 2016-03-11 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides an easy-to-understand introduction to the complex topic of vaccine research and development. It gives a comprehensive though clearly arranged insight to the most important aspects of molecular vaccinology, leading from the basics in immunology, to design of vaccines and mode of action of vaccines to the actual formulation, manufacturing and registration of vaccines. The volume is therefore a valuable text about modern vaccinology for graduate students and a basic introduction for newcomers in vaccine design and development.
Author : Varsha Gupta
Publisher : Springer
ISBN 13 : 9811008752
Total Pages : 543 pages
Book Rating : 4.8/5 (11 download)
Download or read book Basic and Applied Aspects of Biotechnology written by Varsha Gupta and published by Springer. This book was released on 2016-10-22 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the journey of biotechnology, searching for new avenues and noting the impressive accomplishments to date. It has harmonious blend of facts, applications and new ideas. Fast-paced biotechnologies are broadly applied and are being continuously explored in areas like the environmental, industrial, agricultural and medical sciences. The sequencing of the human genome has opened new therapeutic opportunities and enriched the field of medical biotechnology while analysis of biomolecules using proteomics and microarray technologies along with the simultaneous discovery and development of new modes of detection are paving the way for ever-faster and more reliable diagnostic methods. Life-saving bio-pharmaceuticals are being churned out at an amazing rate, and the unraveling of biological processes has facilitated drug designing and discovery processes. Advances in regenerative medical technologies (stem cell therapy, tissue engineering, and gene therapy) look extremely promising, transcending the limitations of all existing fields and opening new dimensions for characterizing and combating diseases.
Author : Guido Grandi
Publisher : John Wiley & Sons
ISBN 13 : 0470093927
Total Pages : 336 pages
Book Rating : 4.4/5 (7 download)
Download or read book Genomics, Proteomics and Vaccines written by Guido Grandi and published by John Wiley & Sons. This book was released on 2004-08-13 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: While the sequence of the human genome sequence has hit the headlines, extensive exploitation of this for practical applications is still to come. Genomic and post-genomic technologies applied to viral and bacterial pathogens, which are almost equally important from a scientific perspective, have the potential to be translated into useful products and processes much more rapidly. Genomics, Proteomics and Vaccines introduces the history of vaccinology and discusses how vaccines are expected to evolve in the future. It describes the relevant technologies, including genome sequencing and analysis, DNA microarrays, 2D electrophoresis and 2D chromatography, mass spectrometry and high-throughput protein expression and purification. The book also features examples of the exploitation of genomics and post-genomics in vaccine discovery, and contains useful descriptions of the biology and pathogenesis of clinically important bacterial pathogens. This book should be of interest to all those working in vaccine discovery and development in pharmaceutical and biotechnology companies as well as in academic institutions
Author : Sunil Thomas
Publisher :
ISBN 13 : 9781493933877
Total Pages : 873 pages
Book Rating : 4.9/5 (338 download)
Download or read book Vaccine Design written by Sunil Thomas and published by . This book was released on 2016 with total page 873 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Namrata Tomar
Publisher : Humana
ISBN 13 : 9781071603918
Total Pages : 409 pages
Book Rating : 4.6/5 (39 download)
Download or read book Immunoinformatics written by Namrata Tomar and published by Humana. This book was released on 2021-03-26 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers a wide range of diverse immunoinformatics research topics, involving tools and databases of potential epitope prediction, HLA gene analysis, MHC characterizing, in silico vaccine design, mathematical modeling of host-pathogen interactions, and network analysis of immune system data. In that way, this fully updated volume explores the enormous value of computational tools and models in immunology research. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of key insights and detailed implementation advice to encourage successful results in the lab. Authoritative and practical, Immunoinformatics, Third Edition serves as an ideal guide for scientists working at the intersection of bioinformatics, mathematical modelling, and statistics for the study of immune systems biology.
Author : Debmalya Barh
Publisher : Academic Press
ISBN 13 : 0128170778
Total Pages : 476 pages
Book Rating : 4.1/5 (281 download)
Download or read book Pan-genomics: Applications, Challenges, and Future Prospects written by Debmalya Barh and published by Academic Press. This book was released on 2020-03-06 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pan-genomics: Applications, Challenges, and Future Prospects covers current approaches, challenges and future prospects of pan-genomics. The book discusses bioinformatics tools and their applications and focuses on bacterial comparative genomics in order to leverage the development of precise drugs and treatments for specific organisms. The book is divided into three sections: the first, an "overview of pan-genomics and common approaches, brings the main concepts and current approaches on pan-genomics research; the second, "case studies in pan-genomics, thoroughly discusses twelve case, and the last, "current approaches and future prospects in pan-multiomics, encompasses the developments on omics studies to be applied on bacteria related studies. This book is a valuable source for bioinformaticians, genomics researchers and several members of biomedical field interested in understanding further bacterial organisms and their relationship to human health. - Covers the entire spectrum of pangenomics, highlighting the use of specific approaches, case studies and future perspectives - Discusses current bioinformatics tools and strategies for exploiting pangenomics data - Presents twelve case studies with different organisms in order to provide the audience with real examples of pangenomics applicability
Author : Paul A. Offit
Publisher : Basic Books (AZ)
ISBN 13 : 0465057969
Total Pages : 298 pages
Book Rating : 4.4/5 (65 download)
Download or read book Deadly Choices written by Paul A. Offit and published by Basic Books (AZ). This book was released on 2015-03-10 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: A renowned researcher vigorously challenges the anti-vaccine movement in this powerful defense of science in the face of fear.
Author : Matthias Frosch
Publisher : John Wiley & Sons
ISBN 13 : 3527614451
Total Pages : 592 pages
Book Rating : 4.5/5 (276 download)
Download or read book Handbook of Meningococcal Disease written by Matthias Frosch and published by John Wiley & Sons. This book was released on 2008-11-21 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive overview of recent advances, from current basic research and epidemiology, to novel therapeutic strategies and clinical management. Here, the leading scientists who have made major advances in the field provide up-to-date reviews and describe their current knowledge and concepts. As such, this is the first volume to summarize the implications of the meningococcus genome-sequencing project, emphasizing the novel strategies in vaccine development. Following a look at the history, the authors go on to treat the epidemiology of meningococcal disease, as well as the genetics, structure and function of virulence factors. Further chapters cover cross-talk between meningococci and host cells, genomics and immunobiology. The result is a standard handbook for all scientists working in the field. While aimed at advanced specialists in basic research, epidemiologists, public health workers, vaccine developers and clinicians, the book is equally appropriate as introductory reading for graduates embarking on their career in this field.
Author : Sunil Thomas
Publisher : Humana
ISBN 13 : 9781071618912
Total Pages : 546 pages
Book Rating : 4.6/5 (189 download)
Download or read book Vaccine Design written by Sunil Thomas and published by Humana. This book was released on 2021-12-17 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a practical guide providing step-by-step methods and protocols on vaccine development and production. Divided into three volumes, Volume 3: Resources for Vaccine Development guides readers through chapters on vaccine adjuvants, vaccine vectors, production, vaccine delivery systems, vaccine bioinformatics, vaccine regulation, and intellectual property. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Vaccine Design: Methods and Protocols, Second Edition, Volume 3: Resources for Vaccine Development aims to be a useful practical guide to researchers to help further their study in this field.
Author : Myrone M. Levine
Publisher : CRC Press
ISBN 13 : 9780824740719
Total Pages : 1120 pages
Book Rating : 4.7/5 (47 download)
Download or read book New Generation Vaccines, Third Edition written by Myrone M. Levine and published by CRC Press. This book was released on 2004-01-28 with total page 1120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated to reflect the wide spectrum of economic, regulatory, financial, ethical, and political issues impacting vaccinology in industrialized and developing nations, the Third Edition pinpoints relevant breakthroughs, trends, and advances in vaccinology and immunization science. The book highlights the most influential developments in vaccine safety, regulation, manufacture, and utilization, as well as clinical trials standardization and monitoring. With contributions from a renowned team of specialists and researchers, this reference tracks the technologies, experimental studies, and international programs that will revolutionize and transform the world of vaccinology in the 21st century.
