Reverse Transcriptase Inhibitors In Hiv Aids Therapy

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Reverse Transcriptase Inhibitors in HIV/AIDS Therapy

Author : Gail Skowron
Publisher : Springer Science & Business Media
ISBN 13 : 1597450855
Total Pages : 536 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Reverse Transcriptase Inhibitors in HIV/AIDS Therapy by : Gail Skowron

Download or read book Reverse Transcriptase Inhibitors in HIV/AIDS Therapy written by Gail Skowron and published by Springer Science & Business Media. This book was released on 2007-11-10 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: A magisterial survey of all aspects of the reverse transcriptase inhibitors (RTIs) used to treat HIV/AIDS, including drug discovery, pharmacology, development of drug resistance, toxicity, and prevention of mother-to-child transmission of HIV/AIDS. The authors synthesize our current understanding of the role of reverse transcriptase in the viral life cycle, describe the discovery and development of eight nucleoside and nucleotide analogs that represent milestones in treatment history, and thoroughly discuss the question of toxicity and resistance to this class of drugs. They also address three non-nucleoside RTIs and their pharmacokinetics and comparative clinical efficacy, new RTIs currently under development, and the impact of approved agents on treatment, in general, and on vertical transmission in the developing world.

Advances in HIV Treatment

Author : Gene D. Morse
Publisher : Bentham Science Publishers
ISBN 13 : 1681080567
Total Pages : 168 pages
Book Rating : 4.6/5 (81 download)

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Book Synopsis Advances in HIV Treatment by : Gene D. Morse

Download or read book Advances in HIV Treatment written by Gene D. Morse and published by Bentham Science Publishers. This book was released on 2016-12-04 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in HIV Treatment: HIV Enzyme Inhibitors and Antiretroviral Therapy presents comprehensive and updated information on drug therapies used to treat and manage HIV infection in human patients. The volume is organized in to chapters detailing respective classes of HIV Drugs including HIV entry inhibitors, reverse transcriptase inhibitors (RTIs), integrase strand inhibitors (INSTIs), and protease inhibitors (PIs). Each chapter compiles background information, pharmacology and clinical aspects such as side effects on the specific classes of drugs represented. Available data for ongoing research for new targets, including vaccines is also presented. Readers will also find a useful introduction to HIV virology and pathogenesis as well as a comparison of the availability and activity of these agents in different populations, opening a discussion on the influence of genetics and resources in curbing the HIV epidemic. Advances in HIV Treatment: HIV Enzyme Inhibitors and Antiretroviral Therapy is, therefore, a holistic resource for researchers, healthcare professionals and clinicians interested in understanding antiretroviral drugs and the management of HIV infection/AIDS. The volume is also of interest to undergraduate and graduate students undertaking specialized courses in pharmacology and HIV/AIDS management.

Reverse Transcriptase Inhibitors in HIV/AIDS Therapy. Infectious Disease

Author : Gail Skowron
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (748 download)

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Book Synopsis Reverse Transcriptase Inhibitors in HIV/AIDS Therapy. Infectious Disease by : Gail Skowron

Download or read book Reverse Transcriptase Inhibitors in HIV/AIDS Therapy. Infectious Disease written by Gail Skowron and published by . This book was released on 2006 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a magisterial survey of all aspects of the reverse transcriptase inhibitors (RTIs) used to treat HIV/AIDS, including drug discovery, pharmacology, development of drug resistance, toxicity, and prevention of mother-to-child transmission of HIV/AIDS. The authors synthesize our current understanding of the role of reverse transcriptase in the viral life cycle, describe the discovery and development of eight nucleoside and nucleotide analogs that represent milestones in treatment history, and thoroughly discuss the question of toxicity and resistance to this class of drugs. They also address three non-nucleoside RTIs and their pharmacokinetics and comparative clinical efficacy, new RTIs currently under development, and the impact of approved agents on treatment, in general, and on vertical transmission in the developing world.

Nucleoside Analog Reverse Transcriptase Inhibitors: Advances in Research and Application: 2011 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464955360
Total Pages : 34 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Nucleoside Analog Reverse Transcriptase Inhibitors: Advances in Research and Application: 2011 Edition by :

Download or read book Nucleoside Analog Reverse Transcriptase Inhibitors: Advances in Research and Application: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 34 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nucleoside Analog Reverse Transcriptase Inhibitors: Advances in Research and Application: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Nucleoside Analog Reverse Transcriptase Inhibitors in a compact format. The editors have built Nucleoside Analog Reverse Transcriptase Inhibitors: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Nucleoside Analog Reverse Transcriptase Inhibitors in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Nucleoside Analog Reverse Transcriptase Inhibitors: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Disease Control Priorities, Third Edition (Volume 6)

Author : King K. Holmes
Publisher : World Bank Publications
ISBN 13 : 1464805253
Total Pages : 1027 pages
Book Rating : 4.4/5 (648 download)

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Book Synopsis Disease Control Priorities, Third Edition (Volume 6) by : King K. Holmes

Download or read book Disease Control Priorities, Third Edition (Volume 6) written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection

Author : World Health Organization
Publisher :
ISBN 13 : 9789241549684
Total Pages : 429 pages
Book Rating : 4.5/5 (496 download)

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Book Synopsis Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection by : World Health Organization

Download or read book Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection written by World Health Organization and published by . This book was released on 2016 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: These guidelines provide guidance on the diagnosis of human immunodeficiency virus (HIV) infection, the use of antiretroviral (ARV) drugs for treating and preventing HIV infection and the care of people living with HIV. They are structured along the continuum of HIV testing, prevention, treatment and care. This edition updates the 2013 consolidated guidelines on the use of antiretroviral drugs following an extensive review of evidence and consultations in mid-2015, shared at the end of 2015, and now published in full in 2016. It is being published in a changing global context for HIV and for health more broadly.

Synthesis of Best-Seller Drugs

Author : Ruben Vardanyan
Publisher : Academic Press
ISBN 13 : 0124115241
Total Pages : 870 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Synthesis of Best-Seller Drugs by : Ruben Vardanyan

Download or read book Synthesis of Best-Seller Drugs written by Ruben Vardanyan and published by Academic Press. This book was released on 2016-01-07 with total page 870 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation

Anti HIV Drugs. Non-Nucleoside Reverse Transcriptase Inhibitors

Author : Amit Patel
Publisher : GRIN Verlag
ISBN 13 : 3656831815
Total Pages : 71 pages
Book Rating : 4.6/5 (568 download)

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Book Synopsis Anti HIV Drugs. Non-Nucleoside Reverse Transcriptase Inhibitors by : Amit Patel

Download or read book Anti HIV Drugs. Non-Nucleoside Reverse Transcriptase Inhibitors written by Amit Patel and published by GRIN Verlag. This book was released on 2014-11-06 with total page 71 pages. Available in PDF, EPUB and Kindle. Book excerpt: Literature Review from the year 2014 in the subject Chemistry - Other, , language: English, abstract: The proposed book entitled, “Anti HIV Drugs: Non-Nucleoside Reverse Transcriptase Inhibitors” gives an outline of the Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTI) class of Anti HIV drugs, from the initial discovery of the class in 1990 to the current compounds in clinical development, i.e. around 20 years of research and development efforts. It describes the characteristics of the NNRTIs, their mechanisms of action, HIV resistance to the inhibitors, and the drugs that have been approved for the treatment of HIV infection, that are currently in clinical development. The role of NNRTIs in prevention of HIV transmission is also addressed. The book also covers some basic information about HIV, AIDS and HIV life cycle.

Combination Therapy of AIDS

Author : Erik De Clercq
Publisher : Birkhäuser
ISBN 13 : 3034878699
Total Pages : 247 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Combination Therapy of AIDS by : Erik De Clercq

Download or read book Combination Therapy of AIDS written by Erik De Clercq and published by Birkhäuser. This book was released on 2012-12-06 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: An extensive assessment of combination therapy of AIDS. Main focus is put on the Highly Active Antiretroviral Therapy (HAART) but other therapies like salvage therapy are also discussed. The chapters cover efficacy, treatment, causes of treatment failure, clinical care, guidelines, pharmacology. The volume closes with an outlook on future perspectives.

HIV and Disability

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 030917712X
Total Pages : 217 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis HIV and Disability by : Institute of Medicine

Download or read book HIV and Disability written by Institute of Medicine and published by National Academies Press. This book was released on 2010-11-17 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Social Security Administration (SSA) uses a screening tool called the Listing of Impairments to identify claimants who are so severely impaired that they cannot work at all and thus qualify for disability benefits. In this report, the Institute of Medicine (IOM) makes several recommendations for improving SSA's capacity for determining disability benefits more accurately and quickly using the HIV Infection Listings.

HIV-1 Integrase

Author : Nouri Neamati
Publisher : John Wiley & Sons
ISBN 13 : 1118015363
Total Pages : 710 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis HIV-1 Integrase by : Nouri Neamati

Download or read book HIV-1 Integrase written by Nouri Neamati and published by John Wiley & Sons. This book was released on 2011-08-10 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery. Despite numerous review articles and isolated book chapters dealing with HIV-1 integrase, there has not been a single source for those working to devise anti-AIDS drugs against this promising target. But this book fills that gap and offers a valuable introduction to the field for the interdisciplinary scientists who will need to work together to design drugs that target HIV-1 integrase.

Advances in HIV Treatment

Author : Gene D. Morse
Publisher :
ISBN 13 : 9781681080574
Total Pages : 168 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Advances in HIV Treatment by : Gene D. Morse

Download or read book Advances in HIV Treatment written by Gene D. Morse and published by . This book was released on 2015-12-04 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in HIV Treatment: HIV Enzyme Inhibitors and Antiretroviral Therapy presents comprehensive and updated information on drug therapies used to treat and manage HIV infection in human patients. The volume is organized in to chapters detailing respective classes of HIV Drugs including HIV entry inhibitors, reverse transcriptase inhibitors (RTIs), integrase strand inhibitors (INSTIs), and protease inhibitors (PIs). Each chapter compiles background information, pharmacology and clinical aspects such as side effects on the specific classes of drugs represented. Available data for ongoing research for new targets, including vaccines is also presented. Readers will also find a useful introduction to HIV virology and pathogenesis as well as a comparison of the availability and activity of these agents in different populations, opening a discussion on the influence of genetics and resources in curbing the HIV epidemic. Advances in HIV Treatment: HIV Enzyme Inhibitors and Antiretroviral Therapy is, therefore, a holistic resource for researchers, healthcare professionals and clinicians interested in understanding antiretroviral drugs and the management of HIV infection/AIDS. The volume is also of interest to undergraduate and graduate students undertaking specialized courses in pharmacology and HIV/AIDS management.

HIV and Its Treatment

Author :
Publisher :
ISBN 13 :
Total Pages : 26 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis HIV and Its Treatment by :

Download or read book HIV and Its Treatment written by and published by . This book was released on 1999 with total page 26 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Antimicrobial Resistance

Author : Matthias Gotte
Publisher : Springer
ISBN 13 : 9781493906932
Total Pages : 0 pages
Book Rating : 4.9/5 (69 download)

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Book Synopsis Handbook of Antimicrobial Resistance by : Matthias Gotte

Download or read book Handbook of Antimicrobial Resistance written by Matthias Gotte and published by Springer. This book was released on 2018-02-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: While many volumes have been written about various aspects of antimicrobial resistance, this book is a comprehensive reference work. All manifestations of resistance are addressed: viral; bacterial, parasitical and fungal are given dedicated sections. The underlining molecular mechanisms, which depend not only on the microbe but on the specific drug (target), are highly diverse. This work discusses and compares the biological, biochemical and structural aspects of resistance and its evolution.

Recent Translational Research in HIV/AIDS

Author : Yi-Wei Tang
Publisher : BoD – Books on Demand
ISBN 13 : 9533077190
Total Pages : 582 pages
Book Rating : 4.5/5 (33 download)

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Book Synopsis Recent Translational Research in HIV/AIDS by : Yi-Wei Tang

Download or read book Recent Translational Research in HIV/AIDS written by Yi-Wei Tang and published by BoD – Books on Demand. This book was released on 2011-11-02 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: The collective efforts of HIV/AIDS research scientists from over 16 countries in the world are included in the book. This 27-chapter Open Access book well covers HIV/AIDS translational researches on pathogenesis, diagnosis, treatment, prevention, and also those beyond conventional fields. These are by no means inclusive, but they do offer a good foundation for the development of clinical patient care. The translational model forms the basis for progressing HIV/AIDS clinical research. When linked to the care of the patients, translational researches should result in a direct benefit for HIV/AIDS patients.

Psychosocial and Public Health Impacts of New HIV Therapies

Author : David G. Ostrow
Publisher : Springer Science & Business Media
ISBN 13 : 0306471590
Total Pages : 232 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis Psychosocial and Public Health Impacts of New HIV Therapies by : David G. Ostrow

Download or read book Psychosocial and Public Health Impacts of New HIV Therapies written by David G. Ostrow and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: “AIDS is kind of like life, just speeded up. ” JavonP. ,heroinaddictwithAIDS, Bronx,NewYork, 1988 “Now I’m not so much scared of dying as scared of living. ” Mike D. , heroin addict with AIDS, New Haven, Connecticut, 1998 Within little more than a decade, AIDS has been tranformed from an untreatable, rapidly fatal illness, into a manageable, chronic disease. Most of this tranformation has occurred in the past five years, accelerated by the advent of protease inhibitors and the proven benefits of combination antiretroviral therapy and prophylaxis against opportunistic infections. For people living with HIV/AIDS, these developments have offered unprecedented hope, and also new challenges. As reflected in the quotes above, some of the anxieties and anticipation of premature dying have been replaced by the uncertainties involved in living with a long-term, unpredictable illness. The role of caregivers for people with HIV/AIDS has also changed radically over this time. Earlier in the epidemic, we learned to accompany patients through illness, to bear witness, to advocate, to address issues of death, dying, and - reavement. The arrival of more effective therapy has brought with it new capabi- ties, but also new complexities, raising difficult problems concerning access to care, adherence, and toxicity.

Nucleoside Reverse Transcriptase Inhibitors: Advances in Research and Application: 2011 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 146495433X
Total Pages : 27 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Nucleoside Reverse Transcriptase Inhibitors: Advances in Research and Application: 2011 Edition by :

Download or read book Nucleoside Reverse Transcriptase Inhibitors: Advances in Research and Application: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nucleoside Reverse Transcriptase Inhibitors: Advances in Research and Application: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Nucleoside Reverse Transcriptase Inhibitors in a compact format. The editors have built Nucleoside Reverse Transcriptase Inhibitors: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Nucleoside Reverse Transcriptase Inhibitors in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Nucleoside Reverse Transcriptase Inhibitors: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.