Retinoids in Oncology

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Author :
Publisher : CRC Press
ISBN 13 : 100014822X
Total Pages : 356 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Retinoids in Oncology by : Waun Ki Hong

Download or read book Retinoids in Oncology written by Waun Ki Hong and published by CRC Press. This book was released on 2020-07-24 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference provides a comprehensive overview of recent developments in basic research that are relevant to the application of retinoids for cancer prevention and treatment.;Organized in a quick-referral format by specific disease site, this book: describes the effects of retinoids on squamous differentiation in normal, pre-malignant, and malignant epithelial tissues; addresses the mechanisms by which cultured keratinocytes respond to retinoids; considers the antitumor activity of combination therapy with retinoids and cytokines; reviews the toxicity profiles of the vitamin A molecule and the synthetically derived retinoid compounds and their effects on humans; examines the use of retinoids in the prevention of basal cell carcinoma and squamous cell carcinoma (SCC) and in the therapy of advanced SCC; and summarizes data on the potential of retinoids to prevent epithelial cancer, to act as adjuvants to current therapies in early stages of the disease and to aid in the management of both solid tumours and hematologic malignancies.;A guide for the many disciplines involved in the preclinical studies and direct care of cancer patients, this book serves as useful reading for clinical, surgical and radiation oncologists; clinical immunologists; dermatologists; obstetricians/gynaecologists; haematologists; otolaryngologists; internists; nutritionists; and pulmonary-disease specialists.

Retinoids in Oncology

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9783540591818
Total Pages : 115 pages
Book Rating : 4.5/5 (918 download)

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Book Synopsis Retinoids in Oncology by : Laurent Degos

Download or read book Retinoids in Oncology written by Laurent Degos and published by Springer Science & Business Media. This book was released on 1995-01-01 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent developments with respect to the biology and clinical use of retinoids in cancer therapy and prevention are comprehensively covered by experts in this new field. Newer aspects of molecular mechanisms of retinoid effects, the cellular biology and the developmental effects of these compounds are presented together with a comprehensive description of the latest findings of retinoid pharmacology, toxicology and clinical effects in a wide range of hematological and solid malignancies.

Retinoids

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Author :
Publisher : IARC
ISBN 13 : 9789283230045
Total Pages : 360 pages
Book Rating : 4.2/5 (3 download)

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Book Synopsis Retinoids by : IARC Working Group on the Evaluation of Cancer-preventive Agents

Download or read book Retinoids written by IARC Working Group on the Evaluation of Cancer-preventive Agents and published by IARC. This book was released on 1999 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Retinoids: Their Physiological Function and Therapeutic Potential

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Author :
Publisher : Elsevier
ISBN 13 : 9780080877174
Total Pages : 296 pages
Book Rating : 4.8/5 (771 download)

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Book Synopsis Retinoids: Their Physiological Function and Therapeutic Potential by : G.V. Sherbet

Download or read book Retinoids: Their Physiological Function and Therapeutic Potential written by G.V. Sherbet and published by Elsevier. This book was released on 1997-10-30 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Retinoids have received considerable attention in recent years and due cognizance has been given to their versatility as biological response modifiers, as evidenced by the virtually explosive growth of literature in this field in the past few years. This volume has been designed to give a current state-of-the-art picture of retinoids. The perceived potential of retinoids in the treatment of certain disease stated has initiated attempts at identifying and synthesizing new retinoid derivatives with definable and selective effects on aberrant biological phenomena. Appropriately, therefore, we begin with the chemistry of retinoids and their derivatives together with discussions of their biological activity. Major advances have been made in understanding the mechanisms by which retinoids modulate physiological and phenotypic traits of cells. The transduction of retinoid signaling by the mediation of nuclear receptors of the steroid/thyroid receptor superfamily has now been studied extensively and the cloning and defining the characteristics of these receptors has been a focus of discussion in this volume. Retinoids also markedly modulate the transduction of extracellular signals such as those imparted by growth factors and hormones, and thus actively influence and control cellular proliferative patterns. Retinoids can alter epidermal growth factor receptor expression (Kawaguchi et al., 1994), responsiveness to thyroid hormone (Esfandiari et al., 1994; Pallet et al., 1994), inhibit the proliferative responses of hematopoietic progenitor cells to granulocyte colony stimulating factor (Smeland et al., 1994), and modulate secretion on interleukins by leukaemic cells (Balitrand et al., 1994), among other things. This has obvious implications for pharmacological manipulation of deregulated growth (Dickens and Colletta, 1993; Mulshine et al., 1993). Apoptosis is another component in the regulation of growth control. Apoptotic cell death is influenced by several agents and retinoids may function by interfering with apoptotic pathways of regulation of growth control and quite legitimately, therefore, the importance of this aspect of retinoid function has been duly recognized here.

Retinoids and Carotenoids in Dermatology

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Author :
Publisher : CRC Press
ISBN 13 : 1420021184
Total Pages : 390 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Retinoids and Carotenoids in Dermatology by : Anders Vahlquist

Download or read book Retinoids and Carotenoids in Dermatology written by Anders Vahlquist and published by CRC Press. This book was released on 2007-06-20 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This up-to-date reference describes how retinoids and carotenoids function in the skin and how they can be utilized to prevent and treat a wide variety of skin diseases, as well as advance biomedical research in relation to cancer treatment and immunology. Providing an in-depth update on the pharmacology, pharmacodynamics, and new applications of

Vitamin A and Retinoids: An Update of Biological Aspects and Clinical Applications

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Author :
Publisher : Birkhäuser
ISBN 13 : 3034884540
Total Pages : 301 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Vitamin A and Retinoids: An Update of Biological Aspects and Clinical Applications by : Maria A. Livrea

Download or read book Vitamin A and Retinoids: An Update of Biological Aspects and Clinical Applications written by Maria A. Livrea and published by Birkhäuser. This book was released on 2012-12-06 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapid progress has been made in our understanding of the molecular mechanisms of cell growth and oncogenesis during the past decade. Special attention has been given to the presentation of the frequently neglected close correlation between changes in signal transduction and metabolic pathways during oncogenesis. This book advances the knowledge of mechanisms regulating metabolism and functioning of vitamin A and offers the most recent results of research on the clinical efficiency of retinoids in skin disorders and cancer. The book presents recent findings on the regulation of cell growth in normal and neoplastic tissues by growth factors including hormones, and by the activation and inactivation of oncogenes and tumor suppressor genes, respectively. It also offers a survey of the molecular and cell biochemistry of retinoids. Basic researchers in biochemistry, pharmacology and cell biology as well as clinicians will find this book very informative and up-to-date. This book advances the knowledge of mechanisms regulating metabolism and functioning of vitamin A and offers the most recent results of research on clinical efficiency of retinoids in skin disorders and cancer. Basic researchers in biochemistry, pharmacology, cell biology, and clinicians will find this book very informative and up-to-date. The chapters, organized in six sections, are contributed by leading scientists who have been working in the retinoid field for decades. Their experience and competence is aknowledged worldwide.

The Retinoids

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118627903
Total Pages : 608 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis The Retinoids by : Pascal Dollé

Download or read book The Retinoids written by Pascal Dollé and published by John Wiley & Sons. This book was released on 2015-05-18 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Retinoids: Biology, Biochemistry, and Disease provides an overview and synthesis of the retinoid molecules, from basic biology to mechanisms of diseases and therapy. Divided into five sections, the book covers retinoic acid signaling from biochemical, genetic, developmental, and clinical perspectives. The text is divided into five sections, the first of which examines vitamin A metabolic and enzymatic pathways. Focus then shifts to the role of retinoic acid signaling in development, and then to retinoids and physiological function. The book concludes with chapters on retinoids, disease and therapy. Comprehensive in scope and written by leading researchers in the field, The Retinoids: Biology, Biochemistry, and Disease will be an essential reference for biologists, biochemists, geneticists and developmental biologists, as well as for clinicians and pharmacists engaged in clinical research involving retinoids.

Retinoids, New Trends in Research and Therapy

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Author :
Publisher : S. Karger AG (Switzerland)
ISBN 13 :
Total Pages : 536 pages
Book Rating : 4.:/5 (45 download)

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Book Synopsis Retinoids, New Trends in Research and Therapy by : Jean-Hilaire Saurat

Download or read book Retinoids, New Trends in Research and Therapy written by Jean-Hilaire Saurat and published by S. Karger AG (Switzerland). This book was released on 1985 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Retinoids: From Basic Science to Clinical Applications

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Author :
Publisher : Birkhäuser
ISBN 13 :
Total Pages : 416 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis Retinoids: From Basic Science to Clinical Applications by : M.A. Livrea

Download or read book Retinoids: From Basic Science to Clinical Applications written by M.A. Livrea and published by Birkhäuser. This book was released on 1994-05-26 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic investigators as well as clinicians will find this volume valuable both as a summary of recent research and as a stimulus for future experimental work in this continuously expanding field.

Cosmetic Dermatology

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Publisher : John Wiley & Sons
ISBN 13 : 1118655486
Total Pages : 560 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Cosmetic Dermatology by : Zoe Diana Draelos

Download or read book Cosmetic Dermatology written by Zoe Diana Draelos and published by John Wiley & Sons. This book was released on 2015-10-08 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Back for a new edition, Zoe Draelos' outstanding resource to cosmetic dermatology again provides a highly-illustrated, clinical guide to the full range of cosmetic skin treatments. Bringing together experts from research, industry, surgery and practice, it is structured in four distinct parts for easy navigation by the busy clinician: Basic Concepts - giving an overview of the physiology pertinent to cosmetic dermatology and the delivery systems by which treatments can take effect; Hygiene Products - evaluating cleansing and moisturising products; Adornment - looking at aesthetic techniques such as cosmetics, nail protheses and hair treatment; Antiaging - ie, injectables, resurfacing and skin contouring techniques, and the rapidly growing area of Cosmeceuticals. With over 300 high-quality images and key summary boxes throughout, this new edition incorporates the newest procedural innovations in this rapidly developing field. Perfect for all dermatologists, especially those specialising in cosmetic dermatology and whether hospital-based or in private practice, it provides the complete cosmetic regimen for your patients and will be an indispensable tool to consult over and over again.

Dermatologic Principles and Practice in Oncology

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118590600
Total Pages : 764 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Dermatologic Principles and Practice in Oncology by : Mario E. Lacouture

Download or read book Dermatologic Principles and Practice in Oncology written by Mario E. Lacouture and published by John Wiley & Sons. This book was released on 2013-11-26 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book focusing specifically on frequent and frequently disabling side effects involving the skin, hair and nails in cancer patients According to the World Health Organization, there are approximately thirty million people living with a diagnosis of cancer – the majority of whom will receive surgery, systemic therapy, and/or radiation, and who will suffer from dermatologic adverse events. Dermatologists and oncologists are only beginning to grapple with these events, which pose serious quality-of-life issues with so many patients, and will become more prevalent as survival rates improve, thanks in part to new cancer treatments and drug regimens. Concentrating on a topic that has only been briefly touched upon by other texts, this book offers a focused perspective on the clinical presentation, underlying pathophysiologic mechanisms, and management of skin, hair, and nail conditions for oncologists, dermatologists, and allied practitioners. Dermatologic Principles and Practice in Oncology: Conditions of the Skin, Hair, and Nails in Cancer Patients: • Covers in detail the dermatologic adverse events of oncologic therapies, clinical presentations, and treatment recommendations • Enables dermatologists and other practitioners to significantly improve the care of patients with cancer • Addresses the dermatologic adverse events of cancer therapies used globally, of which a large number are found in developing countries • Emphasizes prophylactic measures – based on treatments used and type of cancer – to prevent the appearance of adverse events • Provides built-in discussions on patient education for practical counseling during therapies • Offers rapid-reference sections on topical dermatology drugs The first book to present dermatologic conditions in cancer patients and survivors in a uniform and in-depth manner, Dermatologic Principles and Practice in Oncology is ideal for oncologists, oncology nurses, and dermatologists who wish to take better care of those with adverse skin, hair, and nail conditions.

The Retinoids

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118628276
Total Pages : 608 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis The Retinoids by : Pascal Dollé

Download or read book The Retinoids written by Pascal Dollé and published by John Wiley & Sons. This book was released on 2015-04-13 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Retinoids: Biology, Biochemistry, and Disease provides an overview and synthesis of the retinoid molecules, from basic biology to mechanisms of diseases and therapy. Divided into five sections, the book covers retinoic acid signaling from biochemical, genetic, developmental, and clinical perspectives. The text is divided into five sections, the first of which examines vitamin A metabolic and enzymatic pathways. Focus then shifts to the role of retinoic acid signaling in development, and then to retinoids and physiological function. The book concludes with chapters on retinoids, disease and therapy. Comprehensive in scope and written by leading researchers in the field, The Retinoids: Biology, Biochemistry, and Disease will be an essential reference for biologists, biochemists, geneticists and developmental biologists, as well as for clinicians and pharmacists engaged in clinical research involving retinoids.

Retinoids

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642584837
Total Pages : 631 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Retinoids by : Heinz Nau

Download or read book Retinoids written by Heinz Nau and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the future' the decade of the 1990s will likely be viewed as a Golden Age for retinoid research. There have been unprecedented research gains in the understanding of retinoid actions and physiology; since the retinoid nuclear receptors were first identified and the importance of retinoic acid in develop mental processes was first broadly recognized in the late 1980s. Between then and now, our knowledge of retinoid action has evolved from one of a near complete lack of understanding of how retinoids act within cells to one of sophisticated understanding of the molecular processes through which retinoids modulate transcription. In this volume, we have tried to provide a comprehensive update of the present understanding of retinoid actions, with an emphasis on re cent advances. The initial chapters of the volume, or Section A, focus on the physicochemical properties and metabolism of naturally occurring retinoids: - N OY provides an uncommonly encountered view of retinoid effects from the perspective of the physiochemical properties of retinoids. - V AKIANI and BUCK lend a perspective on the biological occurrence and actions of retro- and anhydro-retinoids. Section B considers both the retinoid nuclear receptors and their mechanisms of action as well as synthetic retinoids that have been used exper imentally to provide mechanistic insights into receptor actions and have potential therapeutic use for treating disease: - PIEDRAFITA and PFAHL provide a comprehensive review of retinoid nuclear receptor biochemistry and molecular biology.

Retinoids in Dermatology

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Author :
Publisher : CRC Press
ISBN 13 : 0429852614
Total Pages : 508 pages
Book Rating : 4.4/5 (298 download)

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Book Synopsis Retinoids in Dermatology by : Ayse Serap Karadag

Download or read book Retinoids in Dermatology written by Ayse Serap Karadag and published by CRC Press. This book was released on 2019-10-28 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Retinoids are valuable drugs in the dermatologic armamentarium, being employed in daily clinical practice. The text provides an in-depth update on the latest thinking on pharmacology, clinical use, side effects, and follow-up of retinoid therapy in dermatology; it also addresses topics related to retinoid use in special circumstances, such as vulnerable populations, concomitant surgery, and aesthetic procedures. CONTENTS: The background of retinoids * Mechanism of action of vitamin A * Mechanism of action of topical retinoids * Mechanism of action of isotretinoin * Mechanism of action of acitretin * Mechanism of action of bexarotene * Mechanism of action of alitretinoin * Effects of retinoids at the cellular level (differentiation, apoptosis, autophagy, cell cycle regulation, and senescence) * Effects of retinoids at the systemic level * New aspects of isotretinoin teratogenicity * Mucocutaneous side effects * Ophthalmologic side effects * Musculoskeletal side effects * Neurologic side effects * Psychiatric side effects * Gastrointestinal side effects * Endocrine and metabolic side effecs * Other systemic side effects: Cardiovascular, pulmonary, otolaryngorhinologic, genitourinary, renal, and immunologic * Retinoids in acne * Retinoids in hidradenitis suppurativa/acne inversa * Retinoids in rosacea * Retinoids in hair disorders * Retinoids in psoriasis * Retinoids in keratinization disorders * Retinoids in antiaging therapy * Retinoids in other skin diseases * Retinoids in lymphoma * Retinoids in cutaneous chemoprophylaxis * Guide to good clinical practice for vulnerable populations (infancy, childhood, fertile period, elderly) * Retinoids and concomitant surgery * Retinoids and concomitant aesthetic procedures * Laboratory and clinical follow-up * Teratogenicity and registry programs * Management of vitamin A and retinoid side effects * Future and novel unexplored indications of retinoids Published in association with the Journal of Dermatological Treatment.

Retinoids

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Author :
Publisher : Methods in Molecular Biology
ISBN 13 :
Total Pages : 384 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Retinoids by : Hui Sun

Download or read book Retinoids written by Hui Sun and published by Methods in Molecular Biology. This book was released on 2010-06-08 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exciting new biological functions are still being discovered for vitamin A derivatives, including the myriad physiological activities of retinoids. Here, experts in the field present the latest range of techniques for both in-vitro and in-vivo studies.

Harrison's Manual of Oncology

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Author :
Publisher : McGraw Hill Professional
ISBN 13 : 0071549722
Total Pages : 648 pages
Book Rating : 4.0/5 (715 download)

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Book Synopsis Harrison's Manual of Oncology by : Bruce A. Chabner

Download or read book Harrison's Manual of Oncology written by Bruce A. Chabner and published by McGraw Hill Professional. This book was released on 2007-12-02 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lange Q&A: Mammography Examination is a comprehensive study guide for the ARRT’s Mammography Examination. The book summarizes the mammography curriculum in a clear and concise format and includes review Q&A plus two complete practice exams. With this book, radiographic technicians get the practice they need to pass the registry examination with flying colors.

Syndromes of Hormone Resistance on the Hypothalamic-Pituitary-Thyroid Axis

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1402078528
Total Pages : 210 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Syndromes of Hormone Resistance on the Hypothalamic-Pituitary-Thyroid Axis by : Paolo Beck-Peccoz

Download or read book Syndromes of Hormone Resistance on the Hypothalamic-Pituitary-Thyroid Axis written by Paolo Beck-Peccoz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Truly unique cutting edge state of the art information on basic and clinical research. A great help for the clinician to diagnose and treat this uncommon hormone resistance. Basic scientists learn how much has been discovered on the mechanism of hormone action from the mutations of the various genes involved to thyroid hormones and TSH.