Retinal And Choroidal Vascular Changes And Systemic Diseases In Rats

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Retinal and Choroidal Vascular Changes and Systemic Diseases in Rats

Author : T. Amemiya
Publisher : Springer Science & Business Media
ISBN 13 : 4431683941
Total Pages : 107 pages
Book Rating : 4.4/5 (316 download)

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Book Synopsis Retinal and Choroidal Vascular Changes and Systemic Diseases in Rats by : T. Amemiya

Download or read book Retinal and Choroidal Vascular Changes and Systemic Diseases in Rats written by T. Amemiya and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: Retinal and choroidal vasculatures are easily affected by various systemic diseases, and changes in the retina can easily be observed with various procedures such as direct and indirect ophthalmoscopy, scanning laser ophthalmoscopy, fluorescein fundus angiography, and indocyanin green fundus angiography. Vascular changes are the major, most prominent, and most important fundus changes. The above-mentioned procedures can reveal vascular changes clearly, but mainly reveal changes in the superficial layer of the retina. In addition, these procedures cannot show the three-dimensional architecture of the retina. Usually we can barely obtain the view of that three dimensional architecture. At the same time, pathological findings are well described, but most of them are based on histological and cytological methods. Thus, three-dimensional description of pathology is rare. Vascular corrosion cast scanning electron microscopy can provide a very useful three-dimensional view of the microvasculature and can demonstrate the fine structural architecture of the capillary network. However, the application of this method to the retinal and choroidal vasculature is very difficult, especially in small eyes. We succeeded in making good corrosion casts of retinal and choroidal vessels in the rat. Using this method during the past 10 years we have examined the retinal and choroidal vascular architecture of rats with various systemic diseases such as aging, hypertension, diabetes mellitus, and arteriosclerosis.

Retinal and Choroidal Vascular Changes and Systemic Diseases in Rats

Author : T Amemiya
Publisher :
ISBN 13 : 9784431683957
Total Pages : 92 pages
Book Rating : 4.6/5 (839 download)

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Book Synopsis Retinal and Choroidal Vascular Changes and Systemic Diseases in Rats by : T Amemiya

Download or read book Retinal and Choroidal Vascular Changes and Systemic Diseases in Rats written by T Amemiya and published by . This book was released on 2003-04-23 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vascular changes that occur in the human retina and choroid have frequently been studied through the use of light microscopy. This technique has marked limitations, however, in that it shows changes only in limited localized sites, often with the effects of various systemic diseases indistinguishable. Newer techniques of corrosion cast scanning electron microscopy and transmission electron microscopy provide a much clearer three-dimensional view of retinal and choroidal vasculatures, the results of which will be useful for the interpretation of ocular fundus changes seen in individual systemic diseases. Retinal and choroidal vascular changes due to aging, arteriosclerosis, spontaneous hypertension, and diabetes mellitus in the rat have been investigated and are described in this book, which will be of interest to those in the fields of ophthalmology, anatomy, and pathology. This book is a leading source of information on the use of electron microscopy in a new field of interest. .

Retinal and Choroidal Manifestations of Selected Systemic Diseases

Author : J. Fernando Arévalo
Publisher : Springer Science & Business Media
ISBN 13 : 146143646X
Total Pages : 545 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Retinal and Choroidal Manifestations of Selected Systemic Diseases by : J. Fernando Arévalo

Download or read book Retinal and Choroidal Manifestations of Selected Systemic Diseases written by J. Fernando Arévalo and published by Springer Science & Business Media. This book was released on 2012-08-21 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text presents current information on retinal and choroidal manifestations of systemic diseases from leading experts in the field. Topics include retinal and choroidal manifestations of AIDS, pediatric diseases, toxicity of systemic drugs, diseases of the gastrointestinal tract, diffuse unilateral subacute neuroretinitis (DUSN), viral and fungal diseases, sarcoidosis, Behçet's disease, carotid artery and renal diseases, changes related to pregnancy, intraocular lymphoma, and more. Their knowledge and experience will assist ophthalmologists, retina specialists, uveitis and ocular oncology specialists, and general physicians approach a level of knowledge about retinal and choroidal manifestations of systemic diseases to benefit patients in everyday clinical practice.

Animal Models in Diabetes Research

Author : Hans-Georg Joost
Publisher : Humana Press
ISBN 13 : 9781627030670
Total Pages : 0 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Animal Models in Diabetes Research by : Hans-Georg Joost

Download or read book Animal Models in Diabetes Research written by Hans-Georg Joost and published by Humana Press. This book was released on 2012-08-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, human studies have made enormous contributions towards an understanding of the genetic basis of diabetes mellitus; however, most of the experimentation needed for the invention and testing of novel therapeutic approaches cannot be performed in humans. Thus, there is no alternative to appropriate animal models. In Animal Models in Diabetes Research, expert researchers explore the current status of the most important models and procedures in order to provide a timely resource in experimental diabetology. The first half of the volume serves as a comprehensive overview on our current knowledge of the pathogenesis and pathophysiology of diabetes in animal models through a series of reviews in model strains. The book then continues with vital, established protocols that are employed in the characterization and study of animal models of diabetes. As a volume in the highly successful Methods in Molecular BiologyTM series, this work contains the type of detailed description and key implementation advice necessary to achieve successful results. Authoritative and cutting-edge, Animal Models in Diabetes Research delivers essential content that will be an important resource to advance diabetes research in the years to come.

Fundamental Neuropathology for Pathologists and Toxicologists

Author : Brad Bolon
Publisher : John Wiley & Sons
ISBN 13 : 1118002237
Total Pages : 661 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Fundamental Neuropathology for Pathologists and Toxicologists by : Brad Bolon

Download or read book Fundamental Neuropathology for Pathologists and Toxicologists written by Brad Bolon and published by John Wiley & Sons. This book was released on 2011-08-08 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers pathologists, toxicologists, other medical professionals, and students an introduction to the discipline and techniques of neuropathology – including chemical and environmental, biological, medical, and regulatory details important for performing an analysis of toxicant-induced neurodiseases. In addition to a section on fundamentals, the book provides detailed coverage of current practices (bioassays, molecular analysis, and nervous system pathology) and practical aspects (data interpretation, regulatory considerations, and tips for preparing reports).

Ryan's Retina E-Book

Author : Charles P. Wilkinson
Publisher : Elsevier Health Sciences
ISBN 13 : 0323401988
Total Pages : 2893 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Ryan's Retina E-Book by : Charles P. Wilkinson

Download or read book Ryan's Retina E-Book written by Charles P. Wilkinson and published by Elsevier Health Sciences. This book was released on 2017-04-17 with total page 2893 pages. Available in PDF, EPUB and Kindle. Book excerpt: The undisputed gold standard text in the field, Ryan's Retina is your award-winning choice for the most current, authoritative information on new technologies, surgical approaches, scientific advances and diagnostic and therapeutic options for retinal diseases and disorders. Packed with timely updates throughout, new illustrations, and a dedicated team of editors who extend Dr. Ryan’s legacy in retina, this outstanding 6th Edition is a must-have reference for retinal specialists, ophthalmologists, and fellows in training. Offers the most comprehensive content available on retina, balancing the latest scientific research and clinical correlations, covering everything you need to know on retinal diagnosis, treatment, development, structure, function, and pathophysiology. Provides a truly global perspective from five highly esteemed section editors and more than 350 other world authorities from across Europe, Asia, Australasia, and the Americas. Bullets Includes new chapters on widefield imaging, intraoperative OCT imaging, medical management of diabetes mellitus and age-related macular degeneration, and senile retinoschisis. Includes more than 1,150 brand-new illustrations, scans, and photographs throughout. Covers the explosion of new imaging options across optical coherence tomography (OCT), fundus imaging, and autofluorescence imaging, including a greatly expanded OCT imaging chapter that features crucial information on OCT-Angiography (OCT-A). Presents new pharmacotherapy data and the latest approaches in anti-VEGF therapy for age-related macular degeneration, diabetic retinopathy, and venous occlusive disease. Features an expanded online video library highlighting the latest surgical techniques and new coverage of complications of vitreoretinal surgery. Contains thorough content updates in every area of retina, including advanced imaging technologies, gene therapy, inflammation and immune responses, white dot syndromes, epigenetic mechanisms, transplantation frontiers to improve retinal function, macular hole, myopic eye disease, ocular trauma, drug delivery to the posterior segment, advances in macular surgery, vitrectomy and complex retinal detachment, tumors, and retinal genetics and biology. Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.

Ryan's Retina E-Book

Author : SriniVas R. Sadda
Publisher : Elsevier Health Sciences
ISBN 13 : 0323722148
Total Pages : 2949 pages
Book Rating : 4.3/5 (237 download)

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Book Synopsis Ryan's Retina E-Book by : SriniVas R. Sadda

Download or read book Ryan's Retina E-Book written by SriniVas R. Sadda and published by Elsevier Health Sciences. This book was released on 2022-04-13 with total page 2949 pages. Available in PDF, EPUB and Kindle. Book excerpt: Through six outstanding and award-winning editions, Ryan's Retina has offered unsurpassed coverage of this complex subspecialty—everything from basic science through the latest research, therapeutics, technology, and surgical techniques. The fully revised 7th Edition, edited by Drs. SriniVas R. Sadda, Andrew P. Schachat, Charles P. Wilkinson, David R. Hinton, Peter Wiedemann, K. Bailey Freund, and David Sarraf, continues the tradition of excellence, balancing the latest scientific research and clinical correlations and covering everything you need to know on retinal diagnosis, treatment, development, structure, function, and pathophysiology. More than 300 global contributors share their knowledge and expertise to create the most comprehensive reference available on retina today. - Features sweeping content updates, including new insights into the fundamental pathogenic mechanisms of age-related macular degeneration, advances in imaging including OCT angiography and intraoperative OCT, new therapeutics for retinal vascular disease and AMD, novel immune-based therapies for uveitis, and the latest in instrumentation and techniques for vitreo-retinal surgery. - Includes five new chapters covering Artificial Intelligence and Advanced Imaging Analysis, Pachychoroid Disease and Its Association with Polypoidal Choroidal Vasculopathy, Retinal Manifestations of Neurodegeneration, Microbiome and Retinal Disease, and OCT-Angiography. - Includes more than 50 video clips (35 new to this edition) highlighting the latest surgical techniques, imaging guidance, and coverage of complications of vitreoretinal surgery. New videos cover Scleral Inlay for Recurrent Optic Nerve Pit Masculopathy, Trauma with Contact Lens, Recurrent Retinal Detachment due to PVR, Asteroid Hyalosis, and many more. - Contains more than 2,000 high-quality images (700 new to this edition) including anatomical illustrations, clinical and surgical photographs, diagnostic imaging, decision trees, and graphs. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Research Awards Index

Author :
Publisher :
ISBN 13 :
Total Pages : 826 pages
Book Rating : 4.:/5 (3 download)

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Book Synopsis Research Awards Index by :

Download or read book Research Awards Index written by and published by . This book was released on 1987 with total page 826 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cumulated Index Medicus

Author :
Publisher :
ISBN 13 :
Total Pages : 1828 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1828 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Toxicology Research Projects Directory

Author :
Publisher :
ISBN 13 :
Total Pages : 1058 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicology Research Projects Directory by :

Download or read book Toxicology Research Projects Directory written by and published by . This book was released on 1978 with total page 1058 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Adler's Physiology of the Eye E-Book

Author : Leonard A Levin
Publisher : Elsevier Health Sciences
ISBN 13 : 0323834078
Total Pages : 840 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Adler's Physiology of the Eye E-Book by : Leonard A Levin

Download or read book Adler's Physiology of the Eye E-Book written by Leonard A Levin and published by Elsevier Health Sciences. This book was released on 2024-02-14 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written and designed to enhance your understanding of ocular function, structure, and anatomy, Adler's Physiology of the Eye is a classic, best-selling text that makes critical information easier to learn and retain. The fully revised 12th Edition continues the successful Adler's approach that connects basic science and clinical aspects in a user-friendly, highly visual format—ideal for study, review, and exam preparation. It captures the latest molecular, genetic, and biochemical discoveries and offers you unparalleled knowledge and insight into the physiology of the eye and its structures. - Covers the full structure and function of the eye and its related anatomy and makes the connection between physiology and clinical practice. - Includes major updates throughout, including new information on OCT/OCTA imaging, new drug delivery methods, ocular biomechanics, and evolving gene therapies. - Organizes content by function, rather than anatomy, to help you make a stronger connection between physiological principles and clinical practice. - Explains the physiological principles that underlie visual acuity, intraocular pressure, ocular circulation, the extraocular muscles, and much more. - Features approximately 1,000 illustrations throughout, including medical artwork; schematics, charts, and graphs; clinical photographs; and more. - Any additional digital ancillary content may publish up to 6 weeks following the publication date.

The British National Bibliography

Author : Arthur James Wells
Publisher :
ISBN 13 :
Total Pages : 2248 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The British National Bibliography by : Arthur James Wells

Download or read book The British National Bibliography written by Arthur James Wells and published by . This book was released on 2003 with total page 2248 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Retinal Vascular Disease

Author : A.M. Joussen
Publisher : Springer Science & Business Media
ISBN 13 : 3540295410
Total Pages : 807 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Retinal Vascular Disease by : A.M. Joussen

Download or read book Retinal Vascular Disease written by A.M. Joussen and published by Springer Science & Business Media. This book was released on 2010-03-29 with total page 807 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vascular diseases of the retina are a major cause of blindness among all age groups. Edited and written by internationally well-known experts, this state-of-the-art comprehensive overview of basic and clinical science will enhance the understanding of retinal vascular disease and help in the evaluation of current and future treatment approaches for the clinician. The well-structured and highly illustrated text is divided into three easy-to-follow sections. This unique textbook-atlas also includes topics which are not currently found in other retinal disease textbooks, such as case reports and clinical follow-ups.

Microcirculation in Fractal Branching Networks

Author : Tatsuhisa Takahashi
Publisher : Springer Science & Business Media
ISBN 13 : 4431545085
Total Pages : 150 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Microcirculation in Fractal Branching Networks by : Tatsuhisa Takahashi

Download or read book Microcirculation in Fractal Branching Networks written by Tatsuhisa Takahashi and published by Springer Science & Business Media. This book was released on 2013-09-17 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a new method for analyzing the structure and function of the biological branching systems of fractal trees, with a focus on microcirculation. Branching systems in humans (vascular and bronchial trees) and those in the natural world (plants, trees, and rivers) are characterized by a fractal nature. To date, fractal studies have tended to concentrate on fractal dimensions, which quantify the complexity of objects, but the applications for practical use have remained largely unexplored. This book breaks new ground with topics that include the human retinal microcirculatory network, oxygen consumption by vascular walls, the Fåhraeus-Lindqvist effect, the bifurcation exponent, and the asymmetrical microvascular network. Readers are provided with simple formulas to express functions and a simulation graph with in vivo data. The book also discusses the mechanisms regulating blood flow and pressure and how they are related to pathological changes in the human body. Researchers and clinicians alike will find valuable new insights in these pioneering studies.

Experimental Animal Models of Human Diseases

Author : Bartholomew Ibeh
Publisher : BoD – Books on Demand
ISBN 13 : 1789231647
Total Pages : 410 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Experimental Animal Models of Human Diseases by : Bartholomew Ibeh

Download or read book Experimental Animal Models of Human Diseases written by Bartholomew Ibeh and published by BoD – Books on Demand. This book was released on 2018-05-23 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: The world has recorded losses in terms of human life as well as extensive time spent in experimentation with development of new drugs, elucidation of disease mechanism(s), and therapeutic agent discovery. Ethical and legal issues cojoin in slowing down scientific discoveries in medicine and biology. The past two (2) decades, therefore, have seen tremendous attempts that largely are successful in developing animal models with the characteristics of mimicking, approximating, or expressing transplanted human organs/tissues. These models or rather approaches seem to be fast, cost-effective, and easy to maintain compared to primates. This book is a collection of expert essays on animal models of human diseases of global interest. A visible objective of the book is to provide real-time experimental approach to scientists, clinicians, ethicists, medicolegal/medical jurisprudence workers, immunologists, postgraduate students, and vaccinologists and informative and multidisciplinary approach for the identification of new therapeutic targets and biomarkers using animal models as well as investigating the pathogenesis and therapeutic strategies of human diseases. An increased understanding of the genetic, molecular, and cellular mechanisms responsible for the development of human diseases has laid out the foundation for the development of rational therapies mainly with animal models.

Microvascular Research: Biology and Pathology, Two-Volume Set

Author : David Shepro
Publisher : Elsevier
ISBN 13 : 0126395101
Total Pages : 1353 pages
Book Rating : 4.1/5 (263 download)

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Book Synopsis Microvascular Research: Biology and Pathology, Two-Volume Set by : David Shepro

Download or read book Microvascular Research: Biology and Pathology, Two-Volume Set written by David Shepro and published by Elsevier. This book was released on 2005-11-03 with total page 1353 pages. Available in PDF, EPUB and Kindle. Book excerpt: The microvasculature refers to the smallest blood vessels, arterial and venous, that nurture the tissues of each organ. Apart from transport, they also contribute to the systematic regulation of the body. In everyday terminology, the microcirculation is "where the action is." Microcirculation is directly involved in such disease states as Alzheimers, inflammation, tumor growth, diabetic retinopathy, and wound healing- plus cardiovascular fitness is directly related to the formation of new capillaries in large muscles. Microvascular Research is the first book devoted exclusively to this vital systemic component of the cardiovascular system and provides up to date mini-reviews of normal functions and clinical states. The contributing authors are senior scientists with international reputation in their given disciplines. This two-volume set is a broad, interdisciplinary work that encompasses basic research and clinical applications equally. * Broad coverage of both basic and clinical aspects of microvasculature research * Contains 167 chapters from over 300 international authors * Each chapter includes key figures and annotated references

The Retina and Its Disorders

Author : Joseph Besharse
Publisher : Academic Press
ISBN 13 : 0123821983
Total Pages : 930 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis The Retina and Its Disorders by : Joseph Besharse

Download or read book The Retina and Its Disorders written by Joseph Besharse and published by Academic Press. This book was released on 2011-04-25 with total page 930 pages. Available in PDF, EPUB and Kindle. Book excerpt: This selection of articles from the Encyclopedia of the Eye covering retina, optics/optic nerve and comparative topics constitutes the first reference for scientists, post docs, and graduate students with an interest beyond standard textbook materials. It covers the full spectrum of research on the retina - from the basic biochemistry of how nerve cells are created to information on neurotransmitters, comparisons of the structure and neuroscience of peripheral vision systems in different species, and all the way through to injury repair and other clinical applications. The first single volume to integrate comparative studies into a comprehensive resource on the neuroscience of the retina Chapters are carefully selected from the Encyclopedia of the Eye by one of the world's leading vision researchers The best researchers in the field provide their conclusions in the context of the latest experimental results