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Rethinking Homeostasis
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Book Synopsis Rethinking Homeostasis by : Jay Schulkin
Download or read book Rethinking Homeostasis written by Jay Schulkin and published by MIT Press. This book was released on 2003 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of allostasis, the process by which the body maintains overall viability under normal and adverse conditions.
Book Synopsis RETHINKING HOMEOSTASIS. by : JAY. SCHULKIN
Download or read book RETHINKING HOMEOSTASIS. written by JAY. SCHULKIN and published by . This book was released on 2002 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Allostasis, Homeostasis, and the Costs of Physiological Adaptation by : Jay Schulkin
Download or read book Allostasis, Homeostasis, and the Costs of Physiological Adaptation written by Jay Schulkin and published by Cambridge University Press. This book was released on 2004-10-25 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher Description
Download or read book Rheostasis written by Nicholas Mrosovsky and published by New York : Oxford University Press. This book was released on 1990 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work offers a comprehensive re-examination and elaboration of homeostasis, a guiding principle in physiology that has received surprisingly little critical evaluation. Among the key topics addressed are questions concerning the competing demands of different regulatory systems within the body and the problem of maintaining equilibrium in such circumstances. The author makes the important point that the body does not always seek constancy of its internal environment, nor does it always react in ways that prevent change. On the contrary, sometimes physiological mechanisms actively promote change. These changes in regulated levels--termed "rheostasis"--are seen as having an adaptive value beyond a simple failure of homeostasis. This book compares and categorizes examples of rheostasis for a variety of physiological variables, and presents what is known about conflicts between different regulatory systems and their role in promoting the occurrence of rheostasis. Among other topics covered are weight loss during hibernation, calcium storage and reproduction, fever, and rates of fat deposition in adults. The work of an outstanding scholar, this integrative study represents a refreshing and essential new approach to one of the basic concepts in physiological science.
Book Synopsis Homeostasis by : Leroy Lester Langley
Download or read book Homeostasis written by Leroy Lester Langley and published by . This book was released on 1965 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Missed Information by : David Sarokin
Download or read book Missed Information written by David Sarokin and published by MIT Press. This book was released on 2016-08-26 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: How better information and better access to it improves the quality of our decisions and makes for a more vibrant participatory society. Information is power. It drives commerce, protects nations, and forms the backbone of systems that range from health care to high finance. Yet despite the avalanche of data available in today's information age, neither institutions nor individuals get the information they truly need to make well-informed decisions. Faulty information and sub-optimal decision-making create an imbalance of power that is exaggerated as governments and corporations amass enormous databases on each of us. Who has more power: the government, in possession of uncounted terabytes of data (some of it obtained by cybersnooping), or the ordinary citizen, trying to get in touch with a government agency? In Missed Information, David Sarokin and Jay Schulkin explore information—not information technology, but information itself—as a central part of our lives and institutions. They show that providing better information and better access to it improves the quality of our decisions and makes for a more vibrant participatory society. Sarokin and Schulkin argue that freely flowing information helps systems run more efficiently and that incomplete information does just the opposite. It's easier to comparison shop for microwave ovens than for doctors or hospitals because of information gaps that hinder the entire health-care system. Better information about such social ills as child labor and pollution can help consumers support more sustainable products. The authors examine the opacity of corporate annual reports, the impenetrability of government secrets, and emerging techniques of “information foraging.” The information imbalance of power can be reconfigured, they argue, with greater and more meaningful transparency from government and corporations.
Download or read book What Is Health? written by Peter Sterling and published by MIT Press. This book was released on 2020-02-25 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: An argument that health is optimal responsiveness and is often best treated at the system level. Medical education centers on the venerable “no-fault” concept of homeostasis, whereby local mechanisms impose constancy by correcting errors, and the brain serves mainly for emergencies. Yet, it turns out that most parameters are not constant; moreover, despite the importance of local mechanisms, the brain is definitely in charge. In this book, the eminent neuroscientist Peter Sterling describes a broader concept: allostasis (coined by Sterling and Joseph Eyer in the 1980s), whereby the brain anticipates needs and efficiently mobilizes supplies to prevent errors. Allostasis evolved early, Sterling explains, to optimize energy efficiency, relying heavily on brain circuits that deliver a brief reward for each positive surprise. Modern life so reduces the opportunities for surprise that we are driven to seek it in consumption: bigger burgers, more opioids, and innumerable activities that involve higher carbon emissions. The consequences include addiction, obesity, type 2 diabetes, and climate change. Sterling concludes that solutions must go beyond the merely technical to restore possibilities for daily small rewards and revivify the capacities for egalitarianism that were hard-wired into our nature. Sterling explains that allostasis offers what is not found in any medical textbook: principled definitions of health and disease: health as the capacity for adaptive variation and disease as shrinkage of that capacity. Sterling argues that since health is optimal responsiveness, many significant conditions are best treated at the system level.
Book Synopsis Protein Homeostasis Diseases by : Angel L. Pey
Download or read book Protein Homeostasis Diseases written by Angel L. Pey and published by Academic Press. This book was released on 2020-02-13 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein Homeostasis Diseases: Mechanisms and Novel Therapies offers an interdisciplinary examination of the fundamental aspects, biochemistry and molecular biology of protein homeostasis disease, including the use of natural and pharmacological small molecules to treat common and rare protein homeostasis disorders. Contributions from international experts discuss the biochemical and genetic components of protein homeostasis disorders, the mechanisms by which genetic variants may cause loss-of-function and gain-of-toxic-function, and how natural ligands can restore protein function and homeostasis in genetic diseases. Applied chapters provide guidance on employing high throughput sequencing and screening methodologies to develop pharmacological chaperones and repurpose approved drugs to treat protein homeostasis disorders. Provides an interdisciplinary examination of protein homeostasis disorders, with an emphasis on treatment strategies employing small natural and pharmacological ligands Offers applied approaches in employing high throughput sequencing and screening to develop pharmacological chaperones to treat protein homeostasis disease Gathers expertise from a range of international chapter authors who work across various biological methods and disease specific disciplines of relevance
Book Synopsis Homeostasis Origins of the Concept by : Langley
Download or read book Homeostasis Origins of the Concept written by Langley and published by . This book was released on 1973 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Civic Culture by : Gabriel Abraham Almond
Download or read book The Civic Culture written by Gabriel Abraham Almond and published by Princeton University Press. This book was released on 2015-12-08 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors interviewed over 5,000 citizens in Germany, Italy, Mexico, Great Britain, and the U.S. to learn political attitudes in modem democratic states. Originally published in 1963. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
Book Synopsis Treating Infectious Diseases in a Microbial World by : National Research Council
Download or read book Treating Infectious Diseases in a Microbial World written by National Research Council and published by National Academies Press. This book was released on 2006-01-03 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.
Book Synopsis Textbook of Post-ICU Medicine by : Robert D. Stevens
Download or read book Textbook of Post-ICU Medicine written by Robert D. Stevens and published by Academic. This book was released on 2014 with total page 649 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surviving critical illness is not always the happy ending that we imagine for patients. Intensive care unit (ICU) teams have traditionally focused on short term goals such as stabilizing or reversing organ system dysfunction, with little understanding of what became of patients once they left the ICU. However, research conducted in recent years has demonstrated that many ICU survivors can suffer from ill health and mental health issues for months or years to follow. The Textbook of Post-ICU Medicine: The Legacy of Critical Care identifies the long term outcomes of ICU and the steps that can be taken to improve patients' health and wellbeing. Describing the major clinical syndromes affecting ICU survivors, the book delineates established or postulated biological mechanisms of the post-acute recovery process, and discusses strategies for treatment and rehabilitation to promote recovery in the ICU and in the long term. The book serves as a unique reference for general practitioners, internists and nurses caring for long term ICU survivors as well as specialists in intensive care medicine, neurology, psychiatry, and rehabilitation medicine.
Book Synopsis Flow Cytometry by : Alice Longobardi Givan
Download or read book Flow Cytometry written by Alice Longobardi Givan and published by John Wiley & Sons. This book was released on 2013-04-10 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Flow cytometry continually amazes scientists with its ever-expanding utility. Advances in flow cytometry have opened new directions in theoretical science, clinical diagnosis, and medical practice. The new edition of Flow Cytometry: First Principles provides a thorough update of this now classic text, reflecting innovations in the field while outlining the fundamental elements of instrumentation, sample preparation, and data analysis. Flow Cytometry: First Principles, Second Edition explains the basic principles of flow cytometry, surveying its primary scientific and clinical applications and highlighting state-of-the-art techniques at the frontiers of research. This edition contains extensive revisions of all chapters, including new discussions on fluorochrome and laser options for multicolor analysis, an additionalsection on apoptosis in the chapter on DNA, and new chapters onintracellular protein staining and cell sorting, including high-speed sorting and alternative sorting methods, as well as traditional technology. This essential resource: Assumes no prior knowledge of flow cytometry Progresses with an informal, engaging lecture style from simpleto more complex concepts Offers a clear introduction to new vocabulary, principles of instrumentation, and strategies for data analysis Emphasizes the theory relevant to all flow cytometry, with examples from a variety of clinical and scientific fields Flow Cytometry: First Principles, Second Edition provides scientists, clinicians, technologists, and students with the knowledge necessary for beginning the practice of flow cytometry and for understanding related literature.
Book Synopsis Allostasis, Homeostasis, and the Costs of Physiological Adaptation by : Jay Schulkin
Download or read book Allostasis, Homeostasis, and the Costs of Physiological Adaptation written by Jay Schulkin and published by Cambridge University Press. This book was released on 2004-10-25 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of homeostasis, the maintenance of the internal physiological environment of an organism within tolerable limits, is well established in medicine and physiology. In contrast, allostasis is a relatively new idea of 'viability through change'. With allostatic regulation by cephalic involvement, the body adapts to potentially diverse and dangerous situations through the activation of neural, hormonal, or immunological mechanisms. Allostasis explains how regulatory events maintain organismic viability, or not, in diverse contexts with varying set points of bodily needs and competing motivations. This 2005 book introduces the concept of allostasis and sets it alongside traditional views of homeostasis. It addresses basic regulatory systems and examines the behavior of bodily regulation under duress. The basic concepts of physiological homeostasis are integrated with disorders like depression, stress, anxiety and addiction. It will therefore appeal to graduate students, medical students and researchers working in physiology, epidemiology, endocrinology, neuroendocrinology, neuroscience, and psychology.
Book Synopsis Beyond Mechanism by : Brian G. Henning
Download or read book Beyond Mechanism written by Brian G. Henning and published by Lexington Books. This book was released on 2013-02-01 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been said that new discoveries and developments in the human, social, and natural sciences hang “in the air” (Bowler, 1983; 2008) prior to their consummation. While neo-Darwinist biology has been powerfully served by its mechanistic metaphysic and a reductionist methodology in which living organisms are considered machines, many of the chapters in this volume place this paradigm into question. Pairing scientists and philosophers together, this volume explores what might be termed “the New Frontiers” of biology, namely contemporary areas of research that appear to call an updating, a supplementation, or a relaxation of some of the main tenets of the Modern Synthesis. Such areas of investigation include: Emergence Theory, Systems Biology, Biosemiotics, Homeostasis, Symbiogenesis, Niche Construction, the Theory of Organic Selection (also known as “the Baldwin Effect”), Self-Organization and Teleodynamics, as well as Epigenetics. Most of the chapters in this book offer critical reflections on the neo-Darwinist outlook and work to promote a novel synthesis that is open to a greater degree of inclusivity as well as to a more holistic orientation in the biological sciences.
Download or read book Curt Richter written by Jay Schulkin and published by JHU Press. This book was released on 2020-03-03 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the first half of the twentieth century, psychology was a discipline in search of scientific legitimacy. Debates raged over how much of human and animal behavior is instinctive and how much is learned, and how behavior could be quantified accurately. At the Johns Hopkins University's new Phipps Psychiatric Clinic, Curt P. Richter stood aside from these heated theoretical arguments, choosing instead to apply his data-collection methods, innovative measurement techniques, playful sense of exploration, and consummate surgical skill to laboratory examinations of the biological basis of behavior. From identifying the biological clocks that govern behavior and physiology to observing the self-regulation of nutrient levels by the body, the cyclical nature of some mental illnesses, and the causes of hopelessness, Richter's wide-ranging discoveries not only influenced the burgeoning field of psychobiology and paved the way for later researchers but also often had implications for the treatment of patients in the clinic. At the time of his death in 1988, Richter left behind a massive collection of laboratory data. For this book, Jay Schulkin mined six decades of Richter's archived research data, personal documents, and interviews to flesh out an engaging portrait of a "laboratory artisan" in the context of his work.
Book Synopsis The SAGE Encyclopedia of Theory in Psychology by : Harold L. Miller, Jr.
Download or read book The SAGE Encyclopedia of Theory in Psychology written by Harold L. Miller, Jr. and published by SAGE Publications. This book was released on 2016-01-05 with total page 1173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing together a team of international scholars, The SAGE Encyclopedia of Theory in Psychology examines the contemporary landscape of all the key theories and theorists, presenting them in the context needed to understand their strengths and weaknesses. Key features include: · Approximately 300 signed entries fill two volumes · Entries are followed by Cross-References and Further Readings · A Reader′s Guide in the front matter groups entries thematically · A detailed Index and the Cross-References provide for effective search-and-browse in the electronic version · Back matter includes a Chronology of theory within the field of psychology, a Master Bibliography, and an annotated Resource Guide to classic books in this field, journals, associations, and their websites The SAGE Encyclopedia of Theory in Psychology is an exceptional and scholarly source for researching the theory of psychology, making it a must-have reference for all academic libraries.
