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Author : ED MARKS
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (143 download)
Download or read book RESEARCH METHODS IN NEUROCHEMISTRY. 1972 written by ED MARKS and published by . This book was released on with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Neville Marks
Publisher : Springer Science & Business Media
ISBN 13 : 1461577519
Total Pages : 422 pages
Book Rating : 4.4/5 (615 download)
Download or read book Research Methods in Neurochemistry written by Neville Marks and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Section I Ultrastructure and Fragmentation of Neural Tissue.- 1 Bulk Separation of Neuronal Cell Bodies and Glial Cells in the Absence of Added Digestive Enzymes.- I. Introduction.- II. Bulk Isolation Procedures Requiring No Added Digestive Enzyme(s).- A. The Procedure Developed in the Authors' Laboratory.- B. The Procedure of Nagata et al. (1971).- C. The Procedure of Iqbal and Tellez-Nagel (1972).- D. The Procedure of Jones et al. (1971).- III. General Procedural Comments.- IV. Cell Yield and Biochemical Characterization.- V. Applications in Cellular Neurochemistry.- A. Centrifugal Fractiona.
Author : Neville Marks
Publisher : Springer Science & Business Media
ISBN 13 : 1461577489
Total Pages : 376 pages
Book Rating : 4.4/5 (615 download)
Download or read book Research Methods in Neurochemistry written by Neville Marks and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: On picking up this first volume of a new series of books the reader may ask the two questions: (a) why research methods? and (b) why in neurochem istry? The answers to these questions are easy - they more than justify the volumes to come and show the strong need for their existence. It is customary to think of methods as a necessary but unexciting means to an end - to relegate advances in methodology to a minor role in the creative, original portion of advances in science. This is not the case; the pace-setting function of methodology is well illustrated in most areas of neurobiology. To formulate our questions to Nature (which is the essence of experimental design), methodology is needed; to get answers to our ques tions we have to devise yet new methods. The chapters of the present volume fully illustrate how the development of a new method can cut a new path how it can open new fields, just as the microscope founded histology. Heter ogeneity of structures presents a formidable challenge for methodology in the nervous system, yet methods for separating the structures are essential if we ever want to decipher the enigma of functional contribution of the ele ments to the whole. The problem is not only physical separation-clearly methods are essential to study complex structures in situ.
Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (761 download)
Download or read book Research methods in neurochemistry written by and published by . This book was released on 1972 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Neville Marks
Publisher :
ISBN 13 : 9781461577522
Total Pages : 436 pages
Book Rating : 4.5/5 (775 download)
Download or read book Research Methods in Neurochemistry written by Neville Marks and published by . This book was released on 2014-09-01 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Neville Marks
Publisher : Springer Science & Business Media
ISBN 13 : 1461577543
Total Pages : 450 pages
Book Rating : 4.4/5 (615 download)
Download or read book Research Methods in Neurochemistry written by Neville Marks and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fourth volume of Research Methods in Neurochemistry includes chapters on different aspects of topics touched on in previous volumes and develops a number of new themes as well. The bias, though not entirely intended, is directed toward studies of macromolecules, both at the meta bolic level in relation to protein synthesis and at the structural level in rela tion to specific proteins and lipids. The new departures concern subjects in Section I with marked applied bias: biochemical studies of nervous system tumors and of the cerebrospinal fluid, both of which we hope will be of value to clinical as well as basic scientists. Biogenic amines and the enzymes involved in their metabolism figure again in Section II, where the powerful tool of mass spectrometry receives further treatment in relation to the analysis of dansyl derivatives of trace amines in the brain. Once again we remain grateful to the individual authors, both for their contributions and patience, and to Plenum Press for their continued interest and cooperation. Thanks are also due to colleagues and friends for their comments and criticisms on the series as a whole; suggestions for future volumes will always be welcome and should be sent to one of the editors. Richard Rodnight, London Neville Marks, New York March 1978 ix Contents Section I PROPERTIES OF INTACT NEURAL TISSUES Chapter 1 Biochemical Study of Tumors of the Nervous System. . . . . . . . . . . . . . . . 3 Norman Allen I. Introduction. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 II. Human Brain Tumors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 A. Autopsy Specimens. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Author : Neville Marks
Publisher : Springer Science & Business Media
ISBN 13 : 1461577578
Total Pages : 325 pages
Book Rating : 4.4/5 (615 download)
Download or read book Research Methods in Neurochemistry written by Neville Marks and published by Springer Science & Business Media. This book was released on 2013-11-27 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fifth volume of Research Methods in Neurochemistry represents a milestone in that it marks almost a decade since the inception of the series. Over these ten years there has been an almost exponential growth in neuro chemistry accompanied by numerous technical developments. This is the justification for our series; inevitably we have only been able to cover a frac tion of the methodological innovations of the last decade, but we have tried as much as possible to create a balance between the different approaches and philosophies in the study of the chemical basis of brain function. Thus our original format of grouping chapters under various headings-for instance, studies in intact tissues as distinct from studies describing constituents and isolated enzymes-appears to be justified. Studies on whole animals or tissues retaining cellular organization are vital in providing insights into the neurochemical mechanism underlying functional processes; at the same time, the eventual understanding of function can only be attained on the basis of knowledge of the molecular architecture of the tissue. In the present volume, Oldendorfs chapter on the transport of radiolabeled metabolites across the blood-brain barrier illustrates one side of this equation, whereas Poduslo's chapter on the separation of oligo dendroglia! cells provides new information on the role of these cells in myelogenesis and the distinctive chemical composition of glia as compared to neurons.
Author : Neville Marks
Publisher : Springer Science & Business Media
ISBN 13 : 1461344581
Total Pages : 476 pages
Book Rating : 4.4/5 (613 download)
Download or read book Research Methods in Neurochemistry written by Neville Marks and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the continued rapid expansion of neurochemical research, there has been no shortage of new developments in methodology for this third volume of Research Methods in Neurochemistry. As in previous volumes we have again tried to provide some balance in the subjects represented. The wisdom of this policy may be questioned since it can lead to delay in publica tion, but there are many approaches to the chemical study of the nervous system and a methods book needs to stand on its own as well as be part of a series. In one respect, however, the present volume departs from this policy, in that we have included two chapters on micromethods for analyzing amines and amino acids, both giving special emphasis to dansylation techniques. These chapters are complementary and we feel justified in publishing them in one volume in view of the importance of such micromethods for the study of neural systems. At the other end of the scale, particular attention may be drawn to the chapter by D. D. Gilboe and colleagues describing their remarkable procedures for studying metabolism in the isolated canine brain. We were fortunate also in persuading S. S. Oja to extend the general prin ciples of transport systems he described in Volume 2 to amino acids in brain slices. In addition, there are the usual chapters on components of neural tissues, which once again we have found convenient to divide into enzymes, macromolecules, and other constituents.
Author : Neville Marks
Publisher : Springer Science & Business Media
ISBN 13 : 1461577608
Total Pages : 381 pages
Book Rating : 4.4/5 (615 download)
Download or read book Research Methods in Neurochemistry written by Neville Marks and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (142 download)
Download or read book Research Methods in Neurochemistry, Vol 1 written by and published by . This book was released on 1972 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Earl Usdin
Publisher : Elsevier
ISBN 13 : 1483155862
Total Pages : 1238 pages
Book Rating : 4.4/5 (831 download)
Download or read book Frontiers in Catecholamine Research written by Earl Usdin and published by Elsevier. This book was released on 2014-05-18 with total page 1238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Catecholamine Research is a collection of papers presented at the Third International Catecholamine Symposium, held at the University of Strasbourg, Strasbourg, France, on May 20-25, 1973. This book is organized into nine parts encompassing 205 chapters. The text begins with a discussion on clinically and experimentally used drugs that have been developed or whose mechanism of action has been clarified through monoamine research. Parts II and III deal with enzymes related to catecholamine studies, their properties, regulation, genetics, mechanism of action, and localization. Parts IV and V examine the concepts of synaptic dynamics of brain regulators and the isolation, characterization, methods of analysis, and mechanism of action of catecholamines. Part VI focuses on the complexities that surround the extrapolation of catecholamine function into the realms of electrophysiology and behavior. Part VII discusses the metabolism, behavioral, neurological, and physiological effects of amphetamine and other drugs of abuse. The concluding parts describe the role of catecholamine and its metabolism in neurologic diseases, such as schizophrenia.
Author : University of Michigan. Mental Health Research Institute
Publisher : UM Libraries
ISBN 13 :
Total Pages : 732 pages
Book Rating : 4.3/5 (91 download)
Download or read book Mental Health Research Institute Staff Publications written by University of Michigan. Mental Health Research Institute and published by UM Libraries. This book was released on 1972 with total page 732 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Abel Lajtha
Publisher : Springer Science & Business Media
ISBN 13 : 1468445863
Total Pages : 725 pages
Book Rating : 4.4/5 (684 download)
Download or read book Structural Elements of the Nervous System written by Abel Lajtha and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 725 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurochemistry, having the objective of elucidating biochemical processes subserving nervous activity, emerged as an application of chemistry to the of neurobiological problems as a post-World War II phenomenon. investigation However, only in the last 40 years has the chemical community recognized neurochemistry as a distinct, if hybrid, discipline. During this period great strides have been made. However, recently neurochemistry, along with neu rophysiology, neuropharmacology, neuroanatomy, and the behavioral sci ences, has emerged to form neuroscience, a new community of scientists with its own national society, journals, and meetings. Actually, this recently formed hybrid, neuroscience, is in the process of merging with another well-established discipline, molecular genetics (frequently called molecular biology, and itself a hybrid), which appears to have sufficient hybrid vigor to form yet a new community of scientists, which, for want of a more imaginative term, has been called molecular genetic neuroscience. Clearly, advantages resulting from such mergers or hybridizations accrue not only from the merging discipline (neurochemistry in this case) to the new community (molecular genetic neuroscience), but also in the reverse direction. This Foreword will be concerned primarily with examples of this latter process.
Author : Rokus A. De Zeeuw
Publisher : Elsevier
ISBN 13 : 0444421106
Total Pages : 326 pages
Book Rating : 4.4/5 (444 download)
Download or read book Evaluation of Analytical Methods in Biological Systems: Analysis of biogenic amines written by Rokus A. De Zeeuw and published by Elsevier. This book was released on 1982 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : M. Rocha e Silva
Publisher : Springer Science & Business Media
ISBN 13 : 3642664458
Total Pages : 714 pages
Book Rating : 4.6/5 (426 download)
Download or read book Histamine II and Anti-Histaminics written by M. Rocha e Silva and published by Springer Science & Business Media. This book was released on 2013-11-27 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the preface to Part I of this volume, which appeared in 1966, we stated: " ... we had to leave the Antihistaminics for another volume of unpredictable dimensions. In 1924, eight pages inserted in a Chapter on Mutterkorn by Arthur R.Cushing were considered enough, in Vol. II, Part II, pp. 1319-1326 of the Hand buch. Now 922 pages did not suffice to cover all aspects of the subject ... the subject has been expanded in so many directions, that the anti histaminic part had to be excluded from the present volume. Possibly, another thousand pages will be necessary to cover what remains of the subject."* This prediction was fulfilled, and the subject of histamine has grown to such an extent that dealing with the antihistaminics only in Part II would be quite inadequate. It is imperative to include the large number of recent findings on the subject of histamine, namely the splitting of its pharmacologic receptors, and the great variety of new contributions on ,its participation in physiopathologic phenomena, metabolism and interaction with newly found mediators.
Author : Robert Lahue
Publisher : Springer Science & Business Media
ISBN 13 : 1468438069
Total Pages : 607 pages
Book Rating : 4.4/5 (684 download)
Download or read book Methods in Neurobiology written by Robert Lahue and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapid advances in knowledge have led to an increasing interest in neuro biology over the last several years. These advances have been made possible, at least in part, by the use of increasingly sophisticated methodology. Furthermore, research in the most rapidly advancing areas is essentially multidisciplinary and is characterized by contributions from many investi gators employing a variety of techniques. While a grasp of fundamental neurobiological concepts is an obvious prerequisite for those who wish to follow or participate in this field, critical awareness and evaluation of neurobiological research also requires an understanding of sophisticated methodologies. The objective of Methods in Neurobiology is the development of such critical abilities. The reader is exposed to the basic concepts, principles, and instrumentation of key methodologies, and the application of each meth odology is placed in the special context of neurobiological research. The reader will gain familiarity with the terminology and procedures of each method and the ability to evaluate results in light of the particular features of neurobiological preparations and applications.
Author : Abel Lajtha
Publisher : Springer Science & Business Media
ISBN 13 : 1489945555
Total Pages : 512 pages
Book Rating : 4.4/5 (899 download)
Download or read book Handbook of Neurochemistry written by Abel Lajtha and published by Springer Science & Business Media. This book was released on 2013-11-09 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt:
