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Author : Anil Kumar Sahdev
Publisher :
ISBN 13 : 9783330042315
Total Pages : 52 pages
Book Rating : 4.0/5 (423 download)
Download or read book Resealed Erythrocytes as Drug Carriers Novel Delivery System written by Anil Kumar Sahdev and published by . This book was released on 2017-02-28 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Mauro Magnani
Publisher : Springer Science & Business Media
ISBN 13 : 146153030X
Total Pages : 342 pages
Book Rating : 4.4/5 (615 download)
Download or read book The Use of Resealed Erythrocytes as Carriers and Bioreactors written by Mauro Magnani and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Until recently the only biomedical use of erythrocytes was in transfusion medicine to restore a normal oxygen delivery. The development of a technology that permits one to open and reseal erythrocytes has dramatically changed this perspective. Currently, a number of teams have shown that engineered erythrocytes can behave as circulating bioreactors for the degradation of toxic metabolites or the inactivation of xenobiotics, as drug delivery systems, as carriers of antigens of vaccinal interest, and in many others biomedical applications. The technology of opening and resealing the erythrocytes has also been used successfully to investigate several basic aspects of erythrocyte metabolism, survival, pathology, etc. Thus, researchers in this field have an extraordinary opportunity to specifically modify the erythrocytes by the introduction of enzymes that generate new metabolic abilities, antibodies that inactivate single metabolic steps, or metabolites that can influence oxygen delivery and/or other cell properties. Furthermore, the pharmacokinetics of any drug can be potentially manipulated by using the erythrocytes as a delivery system. This book, The Use of Resealed Erythrocytes, is based on the fourth meeting of the "International Society for the Use of Resealed Erythrocytes as Carriers and Bioreactors" (I. S. U. R. E. ), held in Urbino, Italy, in 1991, and examines the most recent applications and developments of this technology.
Author : Mauro Magnani
Publisher : Springer Science & Business Media
ISBN 13 : 9780306476914
Total Pages : 240 pages
Book Rating : 4.4/5 (769 download)
Download or read book Erythrocyte Engineering for Drug Delivery and Targeting written by Mauro Magnani and published by Springer Science & Business Media. This book was released on 2003-01-31 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Symposia on Plant Lipids, the 15th of which was held in Okazaki, Japan, in May 12-17, 2002, is held every two years and is the only international meeting in this field. The contributions from the symposium collected in this book represent the most up-to-date research results on plant lipids, including their structure, analysis, biosynthesis, regulation, physiological function, environmental aspects, and biotechnology, obtained world-wide during 2000-2002
Author : Ulrich Sprandel
Publisher : Springer Science & Business Media
ISBN 13 : 1489900446
Total Pages : 149 pages
Book Rating : 4.4/5 (899 download)
Download or read book Erythrocytes as Drug Carriers in Medicine written by Ulrich Sprandel and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: The sixth meeting on the use of resealed annealed red blood cells was held in Irsee, Germany by the International Society for the Use of Resealed Erythrocytes (ISURE) on July 25-28, 1996. Although earlier meetings focused on the technology toward develop ment of methods and standardization for efficient, consistent encapsulation, most of the present studies now are directed toward the application use of these carrier blood cells. Basic studies now have been directed toward exploration of commercial applications. In deed, clinical trials were initiated to evaluate the dose-response curves employing L asparagenase in human patients. Also, studies have shown the use of thrombolytic agent in erythrocyte carriers with the use of human red blood cells to provide a new conceptual ap proach in thrombolytic therapy to prevent thrombosis in individuals with higher risk fac tors. For example, with the use of carrier red blood cells, the thrombolytic agents will have a greater potential of acting on clot formation without systemic activation and thus lower the risk of hemorrhage, which is always prevalent in the thrombolytic therapy.
Author : John R. DeLoach
Publisher : Pergamon Press
ISBN 13 : 9780080424965
Total Pages : 200 pages
Book Rating : 4.4/5 (249 download)
Download or read book Carrier and Bioreactor Red Blood Cells for Drug Delivery and Targeting written by John R. DeLoach and published by Pergamon Press. This book was released on 1994-01-01 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of research papers on erythrocyte encapsulation. It covers immunotargeting using erythrocyte carriers and should be useful to those exploring ways to improve drug delivery. It also covers biochemical studies on the erythrocyte and is relevant to studies of circulating bioreactors.
Author : Management Association, Information Resources
Publisher : IGI Global
ISBN 13 : 1522517634
Total Pages : 1614 pages
Book Rating : 4.5/5 (225 download)
Download or read book Pharmaceutical Sciences: Breakthroughs in Research and Practice written by Management Association, Information Resources and published by IGI Global. This book was released on 2016-12-28 with total page 1614 pages. Available in PDF, EPUB and Kindle. Book excerpt: The delivery of optimal pharmaceutical services to patients is a pivotal concern in the healthcare field. By examining current trends and techniques in the industry, processes can be maintained and improved. Pharmaceutical Sciences: Breakthroughs in Research and Practice provides comprehensive coverage of the latest innovations and advancements for pharmaceutical applications. Focusing on emerging drug development techniques and drug delivery for improved health outcomes, this book is ideally designed for medical professionals, pharmacists, researchers, academics, and upper-level students within the growing pharmaceutical industry.
Author : Mauro Magnani
Publisher : Eurekah.Com Incorporated
ISBN 13 : 9781587060618
Total Pages : 148 pages
Book Rating : 4.0/5 (66 download)
Download or read book Erythrocyte Engineering for Drug Delivery and Targeting written by Mauro Magnani and published by Eurekah.Com Incorporated. This book was released on 2003 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : R. L. Juliano
Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 336 pages
Book Rating : 4.3/5 (91 download)
Download or read book Drug Delivery Systems written by R. L. Juliano and published by Oxford University Press, USA. This book was released on 1980 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Vyas; Khar
Publisher :
ISBN 13 : 9788123907994
Total Pages : 594 pages
Book Rating : 4.9/5 (79 download)
Download or read book Targeted & Controlled Drug Delivery: Novel Carrier Systems (HB) written by Vyas; Khar and published by . This book was released on 2006-02-01 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ralph Green
Publisher : Pergamon
ISBN 13 : 9780080411569
Total Pages : 252 pages
Book Rating : 4.4/5 (115 download)
Download or read book Resealed Erythrocytes as Carriers and Bioreactors written by Ralph Green and published by Pergamon. This book was released on 1991-01-01 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : A. M. Kroon
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 352 pages
Book Rating : 4.F/5 ( download)
Download or read book Drug Carrier Systems written by A. M. Kroon and published by John Wiley & Sons. This book was released on 1989 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the main developments of the past 20 years, relating advances in systems that release the active drug in a sustained and controlled way, and new drugs that address more specifically the tissues and cells with which they are designed to interact. Considers the problems of biodistribution and biodegradation, with in-depth discussion of the selectivity and toxicity of the drugs administered by the various carrier systems. Topics covered range from antibodies, polymers, liposomes, erythrocytes and erythrocyte ghosts, to implantable infusion pumps. Acidic paper. Annotation copyrighted by Book News, Inc., Portland, OR
Author : Sonal Vyas
Publisher : CBS Publishers & Distributors Pvt Limited, India
ISBN 13 : 9789388527811
Total Pages : pages
Book Rating : 4.5/5 (278 download)
Download or read book Introduction of Novel Drug Delivery Systems written by Sonal Vyas and published by CBS Publishers & Distributors Pvt Limited, India. This book was released on 2020-01-30 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a useful textbook and resource for undergraduateand postgraduate students and anyone in the working concepts of a drug delivery system and its performance. A novel drug delivery system refers to strategy, technology, formulation-based approaches and customized system(s) developed for safe administration and within body transportation of drugs as needed for optimum therapeutic benefits while ensuring minimum to nil toxic effects. Multidisciplinary approaches and cutting edge technology have been used to develop the carrier modules to deliver the contained drug to the target tissues in a preprogrammed manner. The process desirably modifies the drug distribution and accumulation, thereby producing optimum therapeutic effects. Carrier-mediated drug delivery has emerged as a powerful technology for the treatment of various difficult pathologies. The therapeutic index of conventional and novel drug is enhanced owing to specificity due to targeting of drug to the particular tissue. This book includes an introduction to novel drug delivery, oral osmotic pumps, bioadhesive and mucoadhesive systems, multiple emulsions, colon-specific drug delivery systems, transdermal drug delivery systems, spherical crystallization, microemulsion, implants and inserts, micellar systems, liposomes, microspheres and microcapsules, nanoparticles, resealed erythrocytes, transfersomes and ethosomes, organogels, dendrimers, niosomes, solid lipid nanoparticles, drug conjugates, cyclodextrin complexes, multifunctional nanomedicines, and floating drug delivery system(s). Each chapter attempts to discuss introduction, concept, progress, status and future prospects of the concerned novel drug delivery system.
Author : Sudhakar Yajaman & Jayaveera K.N.
Publisher : S. Chand Publishing
ISBN 13 : 8121942578
Total Pages : pages
Book Rating : 4.1/5 (219 download)
Download or read book Novel Drug Delivery Systems and Regulatory Affairs written by Sudhakar Yajaman & Jayaveera K.N. and published by S. Chand Publishing. This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Novel Drug Delivery Systems | Transdermal Drug Delivery Systems | Mucoadhesive Drug Delivery Systems | Targeted Drugdelivery Systems | Regulatory Agencies | Quality Assurance | Good Manufacturing Practices | Validation
Author : E. Tsuchida
Publisher : Elsevier
ISBN 13 : 008052821X
Total Pages : 409 pages
Book Rating : 4.0/5 (85 download)
Download or read book Blood Substitutes, Present and Future Perspectives written by E. Tsuchida and published by Elsevier. This book was released on 1999-01-14 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the selected papers presented at the seventh International Symposium on Blood Substitutes (7th ISBS) held at the International Conference Center of Waseda University in Tokyo on 7-10 September 1997. In keeping with the scientific design of the 7th ISBS Symposium, chapters have been carefully selected and organized to showcase the advancements in recent research. This book includes up-to-date clinical results of leading companies which are manufacturing hemoglobin-based or fluorocarbon-based blood substitutes, and covers issues of hemoglobin toxicity and side effects such as vasoconstriction in more detail using carefully designed in vivo and ex vivo techniques. This book is also a collection of various new types of red cell substitutes such as recombinant Hbs, recombinant albumine-lipidheme complex, modified red blood cells, and perfluorochemicals using material science and molecular engineering.
Author : V. P. Torchilin
Publisher : Imperial College Press
ISBN 13 : 186094907X
Total Pages : 758 pages
Book Rating : 4.8/5 (69 download)
Download or read book Nanoparticulates as Drug Carriers written by V. P. Torchilin and published by Imperial College Press. This book was released on 2006 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by key experts in the field of nanomedicine, this book provides a broad introduction to the important field of nanomedicine and application of nanotechnology for drug delivery. It covers up-to-date information regarding various nanoparticulate drug delivery systems, describes the various opportunities for the application of nanoparticular drug carriers in different areas of clinical medicine, and analyzes already available information on their clinical applications. This book can be used as an advanced textbook by graduate students and young scientists and clinicians at the early stages of their career. It is also suitable for non-experts from related areas of chemistry, biochemistry, molecular biology, biomedical engineering, physiology, experimental and clinical medicine, and pharmaceutical sciences, who are interested in general problems of drug delivery and drug targeting, as well as in more specialized topics of using nanoparticulate-mediated drug delivery approaches in the individual areas of clinical medicine. Prof Torchilin is an expert in Nanomedicine and a recipient of numerous awards including the Lenin Prize in Science & Technology of the former USSR, membership in the European Academy of Sciences, and AAPS Research Achievement Award in Pharmaceutics and Drug Delivery. He served as an Associate Professor of Radiology at Harvard Medical School before joining Northeastern University as the Chairman of the Department of Pharmaceutical Sciences. Sample Chapter(s). Chapter 1: Introduction. Nanocarriers for Drug Delivery: Needs and Requirements (442 KB). Contents: Nanoparticle Flow: Implications for Drug Delivery (A T Florence); Polymer Micelles as Drug Carriers (E V Batrakova et al.); Lipoproteins as Pharmaceutical Carriers (S Liu et al.); Dendrimers as Nanoparticular Drug Carriers (S Svenson & D A Tomalia); Cells and Cell Ghosts as Drug Carriers (J M Lanao & M L Sayalero); Magnetic Nanoparticles as Drug Carriers (U O Hnfeli & M Chastellain); Liposomal Drug Carriers in Cancer Therapy (A A Gabizon); Delivery of Nanoparticles to the Cardiovascular System (B-A Khaw); Nanoparticles for Targeting Lymphatics (W Phillips); Nanoparticular Carriers for Ocular Drug Delivery (A Sanchez & M J Alonso); and other papers. Readership: Graduate students, academics in nanomedicine, clinicians, pharmacologists, pharmacists, bioengineers, researchers in biotechnology and diagnostic imaging."
Author : Gregory Gregoriadis
Publisher :
ISBN 13 :
Total Pages : 394 pages
Book Rating : 4.3/5 (91 download)
Download or read book Drug Carriers in Biology and Medicine written by Gregory Gregoriadis and published by . This book was released on 1979 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Academic Press
ISBN 13 : 0128144556
Total Pages : 974 pages
Book Rating : 4.1/5 (281 download)
Download or read book The Future of Pharmaceutical Product Development and Research written by and published by Academic Press. This book was released on 2020-09-02 with total page 974 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Future of Pharmaceutical Product Development and Research examines the latest developments in the pharmaceutical sciences, also highlighting key developments, research and future opportunities. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of the product development phase of drug discovery and drug development. Each chapter covers fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and the pharmaceutical industry. The book focuses on excipients, radiopharmaceuticals, and how manufacturing should be conducted in an environment that follows Good Manufacturing Practice (GMP) guidelines. Researchers and students will find this book to be a comprehensive resource for those working in, and studying, pharmaceuticals, cosmetics, biotechnology, foods and related industries. Provides an overview of practical information for clinical trials Outlines how to ensure an environment that follows Good Manufacturing Practice (GMP) Examines recent developments and suggests future directions for drug production methods and techniques
