Regulatory Toxicology in the European Union

Download Regulatory Toxicology in the European Union PDF Online Free

Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 1782620664
Total Pages : 638 pages
Book Rating : 4.7/5 (826 download)

DOWNLOAD NOW!


Book Synopsis Regulatory Toxicology in the European Union by : Tim Marrs

Download or read book Regulatory Toxicology in the European Union written by Tim Marrs and published by Royal Society of Chemistry. This book was released on 2018-02-26 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt: Consumer and environmental protection depend on the careful regulation of all classes of chemicals. Toxicology is the key science used to evaluate safety and so underpins regulatory decisions on chemicals. With the growing body of EU legislation involved in chemical regulation, there is a concomitant need to understand the toxicological principles underlying safety assessments. Regulatory Toxicology in the European Union is the first book to cover regulatory toxicology specifically in Europe. It addresses the need for a wider understanding of the principles of regulatory toxicology and their application and presents the relationship between toxicology and legislative processes in regulating chemical commodities across Europe. This title has a broad scope, covering historical and current chemical regulation in Europe, the role of European agencies and institutions, and also the use of toxicology data for important classes of chemicals, including human and veterinary medicines, animal feed and food additives, biocides, pesticides and nanomaterials. This book is therefore extremely pertinent and timely in the toxicology field at present. This book is an essential reference for regulatory authorities, industrialists, academics, undergraduates and postgraduates working within safety and hazards, toxicology, the biological sciences, and the medicinal and pharmaceutical sciences across the European Union.

Regulatory Toxicology, Third Edition

Download Regulatory Toxicology, Third Edition PDF Online Free

Author :
Publisher : CRC Press
ISBN 13 : 0429876521
Total Pages : 367 pages
Book Rating : 4.4/5 (298 download)

DOWNLOAD NOW!


Book Synopsis Regulatory Toxicology, Third Edition by : Shayne C. Gad

Download or read book Regulatory Toxicology, Third Edition written by Shayne C. Gad and published by CRC Press. This book was released on 2018-09-03 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: • Describes regulatory testing requirements for all the major classes of marketed products • Explains how to prepare required documents for mandated safety testing of product • Features new chapters addressing Safety Data Sheet Preparation and Regulatory Requirements for GMOs • Covers Safety Data Sheet Preparation, which has replaced the Material Safety Data Sheet system

Regulatory Toxicology, Second Edition

Download Regulatory Toxicology, Second Edition PDF Online Free

Author :
Publisher : CRC Press
ISBN 13 : 9781420025187
Total Pages : 424 pages
Book Rating : 4.0/5 (251 download)

DOWNLOAD NOW!


Book Synopsis Regulatory Toxicology, Second Edition by : Shayne C. Gad

Download or read book Regulatory Toxicology, Second Edition written by Shayne C. Gad and published by CRC Press. This book was released on 2001-07-19 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical resource provides toxicologists and scientists with essential information on the regulations that govern their jobs and products. Regulatory Toxicology also covers the scientific and historical underpinnings of those regulations. Each chapter provides a grounding in the historical events that led to the development of original legislation and major subsequent changes in legislation. The major administrative divisions for regulatory agencies and their main missions and responsibilities are also detailed, as are the basic filing units or documents the agencies require of individuals to meet goals. This second edition is updated to reflect new developments in the field.

Regulation for Chemical Safety in Europe: Analysis, Comment and Criticism

Download Regulation for Chemical Safety in Europe: Analysis, Comment and Criticism PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9401153167
Total Pages : 214 pages
Book Rating : 4.4/5 (11 download)

DOWNLOAD NOW!


Book Synopsis Regulation for Chemical Safety in Europe: Analysis, Comment and Criticism by : D.M. Pugh

Download or read book Regulation for Chemical Safety in Europe: Analysis, Comment and Criticism written by D.M. Pugh and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many European Union Directives seek to minimize the potential for harm to humans and the environment arising from the use of chemicals. This book takes an interdisciplinary, selective look at the effector mechanisms employed in such directives. It covers the pre-marketing use of toxicology to identify the hazardous properties of chemicals, acknowledging its shortcomings, while contrasting the scientific method with the precautionary principle in developing risk-management practices. The book then goes on to describe the use of bio-indicators, chemical analyses and mathematical modelling for prediction, or to determine the adequacy of chemical safety legislation. The environmental risk assessment of priority chemicals is described and the impact of pesticides on sustainability in agriculture is discussed from the differing standpoints of agronomy and economics. Audience: All professionals concerned with the safe management of chemicals and their use, including teachers, practitioners, policy makers or legislators.

Regulating Chemical Risks

Download Regulating Chemical Risks PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9048194288
Total Pages : 347 pages
Book Rating : 4.0/5 (481 download)

DOWNLOAD NOW!


Book Synopsis Regulating Chemical Risks by : Johan Eriksson

Download or read book Regulating Chemical Risks written by Johan Eriksson and published by Springer Science & Business Media. This book was released on 2010-08-18 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents research on current trends in chemical regulations – a fa- growing, complex, and increasingly internationalized field. The book grew out from a multidisciplinary research project entitled ‘Regulating Chemical Risks in the Baltic Sea Area: Science, Politics, and the Media’, led by Michael Gilek at Södertörn University, Sweden. This research project involved scholars and experts from natural as well as social sciences, based at Södertörn University, Swedish Royal Institute of Technology (KTH), Karolinska Institutet, and Umeå University. The project group organized a multidisciplinary research conference on chemical risk regulations, held in Stockholm, August 15–17, 2007. Most of the contributions published in this book were, in draft form, first presented at this conference. The conference, like the ensuing edited volume, expanded the geographical focus beyond the Baltic Sea area to include wider European, and to some extent also global trends. Many thanks to all project colleagues and conference participants! We are very grateful for the generous financial support received from The Foundation for Baltic and East European Studies (Östersjöstiftelsen), The Swedish Research Council Formas, and from Södertörn University. Without this support the present book would not have been possible. Special thanks to all of our fellow contributors, all of whom have submitted to- cal papers based on high-quality research. Many thanks also to Tobias Evers, who assisted us with technical editing. Finally, we are grateful for the professionalism shown by our editors at Springer.

Regulatory Toxicology

Download Regulatory Toxicology PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 9783642353734
Total Pages : 0 pages
Book Rating : 4.3/5 (537 download)

DOWNLOAD NOW!


Book Synopsis Regulatory Toxicology by : Franz-Xaver Reichl

Download or read book Regulatory Toxicology written by Franz-Xaver Reichl and published by Springer. This book was released on 2014-03-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will be written by experts for professionals, scientists and all those involved in toxicological data generation and decision-making. It is the updated and expanded version of a monograph published in German in 2004. Chemical safety is regulated on various levels including production, storage, transport, handling, disposal or labelling. This book deals comprehensively with the safety-ensuring methods and concepts employed by regulatory agencies, industry and academics. Toxicologists use experimental and scientific approaches for data collection, e.g. about chemical hazards, physicochemical features or toxicokinetics. The respective experimental methods are described in the book. Toxicologists also deal with much insecurity in the exposure and effect scenarios during risk assessment. To overcome these, they have different extrapolation methods and estimation procedures at their disposal. The book describes these methods in an accessible manner. Differing concepts from one regulation area to another are also covered. Reasons and consequences become evident when reading the book. Altogether, the book Regulatory Toxicology will serve as an excellent reference.

Regulatory Toxicology in the European Union

Download Regulatory Toxicology in the European Union PDF Online Free

Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 1788014049
Total Pages : 638 pages
Book Rating : 4.7/5 (88 download)

DOWNLOAD NOW!


Book Synopsis Regulatory Toxicology in the European Union by : Tim Marrs

Download or read book Regulatory Toxicology in the European Union written by Tim Marrs and published by Royal Society of Chemistry. This book was released on 2018-02-21 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt: Consumer and environmental protection depend on the careful regulation of all classes of chemicals. Toxicology is the key science used to evaluate safety and so underpins regulatory decisions on chemicals. With the growing body of EU legislation involved in chemical regulation, there is a concomitant need to understand the toxicological principles underlying safety assessments Regulatory Toxicology in the European Union is the first book to cover regulatory toxicology specifically in Europe. It addresses the need for a wider understanding of the principles of regulatory toxicology and their application and presents the relationship between toxicology and legislative processes in regulating chemical commodities across Europe. This title has a broad scope, covering historical and current chemical regulation in Europe, the role of European agencies and institutions, and also the use of toxicology data for important classes of chemicals, including human and veterinary medicines, animal feed and food additives, biocides, pesticides and nanomaterials. This book is therefore extremely pertinent and timely in the toxicology field at present. This book is an essential reference for regulatory authorities, industrialists, academics, undergraduates and postgraduates working within safety and hazards, toxicology, the biological sciences, and the medicinal and pharmaceutical sciences across the European Union.

Good Manufacturing Practice (GMP) Guidelines

Download Good Manufacturing Practice (GMP) Guidelines PDF Online Free

Author :
Publisher : Pharmalogika
ISBN 13 : 9780982147603
Total Pages : 686 pages
Book Rating : 4.1/5 (476 download)

DOWNLOAD NOW!


Book Synopsis Good Manufacturing Practice (GMP) Guidelines by : Mindy J. Allport-Settle

Download or read book Good Manufacturing Practice (GMP) Guidelines written by Mindy J. Allport-Settle and published by Pharmalogika. This book was released on 2009-12 with total page 686 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title combines all of the human and veterinary Regulations, Directives and guidance for medicinal products used by the pharmaceutical industry as their main source when manufacturing and distributing medicinal products in the European Union.

Pesticide Toxicology and International Regulation

Download Pesticide Toxicology and International Regulation PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 9780471496441
Total Pages : 586 pages
Book Rating : 4.4/5 (964 download)

DOWNLOAD NOW!


Book Synopsis Pesticide Toxicology and International Regulation by : Timothy T. Marrs

Download or read book Pesticide Toxicology and International Regulation written by Timothy T. Marrs and published by John Wiley & Sons. This book was released on 2004-02-13 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dieser Band gehört zur bekannten Wiley-Reihe 'Current Toxicology Series' und befasst sich ausführlich mit der Pestizidtoxikologie. Untersucht werden Pestizide nach Gruppen (z. B. Insektizide und Fungizide), ihre Rückstände in Lebensmitteln sowie die Metabolisierung von Pestiziden. Darüber hinaus werden berufsbezogene Aspekte und die Behandlung von Vergiftungserscheinungen umfassend diskutiert. "Pesticide Toxicology" ist das erste einbändige Werk zum Thema Pestizide, das spezialisierte und dennoch umfassende Informationen sowohl für Experten als auch für Doktoranden bereit hält. Herausgeber Timothy Marrs ist ein international anerkannter Experte in der Pestizidforschung und genießt großes Ansehen auf dem Gebiet der Toxikologie. Geschrieben wurde der Band von einem Team international renommierterToxikologen.

Regulatory Toxicology

Download Regulatory Toxicology PDF Online Free

Author :
Publisher : CRC Press
ISBN 13 : 9780781701914
Total Pages : 239 pages
Book Rating : 4.7/5 (19 download)

DOWNLOAD NOW!


Book Synopsis Regulatory Toxicology by : Christopher P. Chengelis

Download or read book Regulatory Toxicology written by Christopher P. Chengelis and published by CRC Press. This book was released on 1995-06-30 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical resource provides all toxicolgists and scientists with essential information on the regulations that govern the context and the content of their jobs and products. The book also covers the scientific and historical underpinnings of those regulations.; The first six chapters cover the major classes of chemicals in commerce in the United States, namely human medicaments, veterinary products, cosmetics, consumer products, commercial chemicals and pesticides. The remaining chapters discuss the toxicological data required for OSHA regulations, the differences between the United States, Europe and Japan with regard to regulatory requirements, and recent areas of special interest, such as immunotoxicological and neurobehavioural testing.; Each chapter provides a grounding in the historical events that led to the development of original legislation and major subsequent changes in legislation. The major administrative divisions for regulatory agencies and their main missions and responsibilities are also detailed, as are the basic filing units or documents the agencies require of individuals to meet goals.

Mixture Toxicity

Download Mixture Toxicity PDF Online Free

Author :
Publisher : CRC Press
ISBN 13 : 1439830096
Total Pages : 312 pages
Book Rating : 4.4/5 (398 download)

DOWNLOAD NOW!


Book Synopsis Mixture Toxicity by : Cornelis A. M. van Gestel

Download or read book Mixture Toxicity written by Cornelis A. M. van Gestel and published by CRC Press. This book was released on 2016-04-19 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last decade and a half, great progress has been made in the development of concepts and models for mixture toxicity, both in human and environmental toxicology. However, due to their different protection goals, developments have often progressed in parallel but with little integration. Arguably the first book to clearly link ecotoxicology an

Validation of Alternative Methods for Toxicity Testing

Download Validation of Alternative Methods for Toxicity Testing PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 3319338269
Total Pages : 407 pages
Book Rating : 4.3/5 (193 download)

DOWNLOAD NOW!


Book Synopsis Validation of Alternative Methods for Toxicity Testing by : Chantra Eskes

Download or read book Validation of Alternative Methods for Toxicity Testing written by Chantra Eskes and published by Springer. This book was released on 2016-09-26 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides information on best practices and new thinking regarding the validation of alternative methods for toxicity testing. It covers the validation of experimental and computational methods and integrated approaches to testing and assessment. Validation strategies are discussed for methods employing the latest technologies such as tissue-on-a-chip systems, stem cells and transcriptomics, and for methods derived from pathway-based concepts in toxicology. Validation of Alternative Methods for Toxicity Testing is divided into two sections, in the first, practical insights are given on the state-of-the-art and on approaches that have resulted in successfully validated and accepted alternative methods. The second section focuses on the evolution of validation principles and practice that are necessary to ensure fit-for-purpose validation that has the greatest impact on international regulatory acceptance of alternative methods. In this context validation needs to keep pace with the considerable scientific advancements being made in toxicology, the availability of sophisticated tools and techniques that can be applied in a variety of ways, and the increasing societal and regulatory demands for better safety assessment. This book will be a useful resource for scientists in the field of toxicology, both from industry and academia, developing new test methods, strategies or techniques, as well as Governmental and regulatory authorities interested in understanding the principles and practicalities of validation of alternative methods for toxicity testing.

Drug Discovery and Evaluation: Methods in Clinical Pharmacology

Download Drug Discovery and Evaluation: Methods in Clinical Pharmacology PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3540898905
Total Pages : 576 pages
Book Rating : 4.5/5 (48 download)

DOWNLOAD NOW!


Book Synopsis Drug Discovery and Evaluation: Methods in Clinical Pharmacology by : H.Gerhard Vogel

Download or read book Drug Discovery and Evaluation: Methods in Clinical Pharmacology written by H.Gerhard Vogel and published by Springer Science & Business Media. This book was released on 2010-12-15 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".

Toxicity Testing in the 21st Century

Download Toxicity Testing in the 21st Century PDF Online Free

Author :
Publisher : National Academies Press
ISBN 13 : 0309151732
Total Pages : 217 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis Toxicity Testing in the 21st Century by : National Research Council

Download or read book Toxicity Testing in the 21st Century written by National Research Council and published by National Academies Press. This book was released on 2007-11-05 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in molecular biology and toxicology are paving the way for major improvements in the evaluation of the hazards posed by the large number of chemicals found at low levels in the environment. The National Research Council was asked by the U.S. Environmental Protection Agency to review the state of the science and create a far-reaching vision for the future of toxicity testing. The book finds that developing, improving, and validating new laboratory tools based on recent scientific advances could significantly improve our ability to understand the hazards and risks posed by chemicals. This new knowledge would lead to much more informed environmental regulations and dramatically reduce the need for animal testing because the new tests would be based on human cells and cell components. Substantial scientific efforts and resources will be required to leverage these new technologies to realize the vision, but the result will be a more efficient, informative and less costly system for assessing the hazards posed by industrial chemicals and pesticides.

Safety Evaluation of Medical Devices

Download Safety Evaluation of Medical Devices PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 408 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis Safety Evaluation of Medical Devices by : Shayne C. Gad

Download or read book Safety Evaluation of Medical Devices written by Shayne C. Gad and published by . This book was released on 1997 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This practical reference examines the implications of biological and chemical interactions of medical devices with human tissue - offering comprehensive coverage on the evaluation of safety in specialty devices, medical and surgical supplies, imaging systems, in vitro diagnostics, and health information systems." "Discussing preapproval and ongoing test requirements necessary for the development of new products, Safety Evaluation of Medical Devices shows how to select individual materials, components, or devices for testing and how to prepare the samples selected...explains cytotoxicity testing for the determination of biocompatibility using mammalian cell cultures...details the evaluation of hemocompatibility and the potential adverse effects of medical devices on the immune system...addresses studies for both short- and long-term implantable devices...delineates possible genotoxic effects of device materials...presents appropriate models for clinical studies of medical devices...describes specialized studies for cardiovascular prostheses, contact lenses and solutions, and tampons as well as the "mouse safety" systemic injection test...and much more."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved

Novel Foods in the European Union

Download Novel Foods in the European Union PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 3319936204
Total Pages : 54 pages
Book Rating : 4.3/5 (199 download)

DOWNLOAD NOW!


Book Synopsis Novel Foods in the European Union by : Daniele Pisanello

Download or read book Novel Foods in the European Union written by Daniele Pisanello and published by Springer. This book was released on 2018-06-09 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Brief describes in three concise chapters one of the newest ‘hot topics’ under EU Food Law and Policy: the new Regulation (EU) No 2015/2283 from the European Parliament and by the Council, November 25, 2015, on novel foods, applicable from January 2018. In this work, the Authors discuss the long-time criticized EU Regulation on novel foods ((EC) No 258/1997) and how it has been significantly altered by the adoption of the new regulation. In the first chapter, the Authors provide a comprehensive analysis of the genesis of the new Regulation, its rationale and the policy’s goals. In particular, they describe what food business operators shall do in order to get a new product allowed on the EU market, providing updated information on the regulatory developments from the European Food Safety Authority in nanofoods, cloned animals and insect foods. The role of the European Food Safety Authority is also discussed. The second Chapter summarizes the current toxicological studies used to evaluate novel foods safety, which are an extremely important pillar when speaking of food safety and commercial introduction of new products. Finally, the third Chapter discusses the ‘history of safe use’ approach to the problem of novel foods, and factors such as consumption period analysis, preparation advices and processes, intake levels, nutritional composition, and results of animal studies. Food lawyers, professionals and auditors working in the area of official inspections, quality assurance, food traceability, and international regulation, both in academia and industry, will find this Brief an important account.

The Toxic Substances Control Act

Download The Toxic Substances Control Act PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 20 pages
Book Rating : 4.3/5 (121 download)

DOWNLOAD NOW!


Book Synopsis The Toxic Substances Control Act by :

Download or read book The Toxic Substances Control Act written by and published by . This book was released on 1984 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: