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Author : Tommy Andersson
Publisher :
ISBN 13 : 9789172228849
Total Pages : 23 pages
Book Rating : 4.2/5 (288 download)
Download or read book Regulation of Xenobiotic Metabolism in Rainbow Trout Liver written by Tommy Andersson and published by . This book was released on 1985 with total page 23 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Paul Ortiz De Monetllano
Publisher : Springer Science & Business Media
ISBN 13 : 9780306421471
Total Pages : 572 pages
Book Rating : 4.4/5 (214 download)
Download or read book Cytochrome P-450 written by Paul Ortiz De Monetllano and published by Springer Science & Business Media. This book was released on 1986-03 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Major advances have been made in recent years in clarifying the molecular properties of the cytochrome P-450 system. These advances stem, in practical terms, from the generally recognized importance of cytochrome P-450 in the metabolism of drugs and in the bioactivation of xenobiotics to toxic products. The fascinating multiplicity and differential regulation of cytochrome P-450 isozymes, and their ability to catalyze extraordinarily difficult chemical transformations, have independently drawn many chemists and biochemists into the P-450 circle. Progress in the field, from a technical point of view, has been propelled by the de velopment of reliable procedures for the purification of membrane-bound enzymes, by the growing repertoire of molecular biological techniques, and by the development of chemical models that mimic the catalytic action of P-450. As a result, our understanding of the P-450 system is moving from the descriptive, pharmacological level into the tangible realm of atomic detail. The rapid progress and multidisciplinary character of the cytochrome P-450 field, which cuts across the lines that traditionally divide disciplines as diverse as inorganic chemistry and genetics, have created a need for an up-to-date evaluation of the advances that have been made. It is hoped that this book, with its molecular focus on the cytochrome P-450 system, will alleviate this need. The authors of the individual chapters have strived to emphasize recent results without sacrificing the background required to make their chapters comprehensible to informed nonspecialists.
Author : Robert C. Smart
Publisher : John Wiley & Sons
ISBN 13 : 1118679725
Total Pages : 804 pages
Book Rating : 4.1/5 (186 download)
Download or read book Molecular and Biochemical Toxicology written by Robert C. Smart and published by John Wiley & Sons. This book was released on 2013-03-05 with total page 804 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential resource for graduate students, academic and industrial toxicologists, and environmental health scientists and professionals Over the course of thirty years and three editions, Introduction to Biochemical Toxicology has been an important source for coverage of the ongoing quest to define the biochemical, cellular, and molecular events induced by toxicants at the cellular and organismic levels. Now, as the principles and methods of molecular and cellular biology as well as genomic sciences play an ever increasing role in mechanistic toxicology, significant changes have been made to the book, resulting in this important new edition-now titled Molecular and Biochemical Toxicology, Fourth Edition. Much more than an introductory text, this crucial new edition has been completely revised to provide timely and thorough coverage of the underlying biochemical, molecular, and cellular mechanisms through which toxicants produce their adverse effects. Toxicological issues are covered from the molecule to the cell to the organ level. Complex methods used in toxicology are also described in a straightforward, easy-to-understand style. Additional features of this new edition include: New chapters that explore the interface between toxicology and genomic sciences, including: bioinformatics, proteomics, metabolomics, and toxicogenomics Increased emphasis on structure, mechanism, and regulation of xenobiotic metabolizing enzymes, toxicogenetics, and xenobiotic transporters Additional new chapters on: molecular epidemiology and genetic susceptibility, DNA damage and mutagenesis, DNA repair, mechanisms of cell death, mitochondrial dysfunction, metals, reproductive toxicology, developmental toxicology, and reactive oxygen/metabolites and toxicity Molecular and Biochemical Toxicology, Fourth Edition guides graduate students, toxicologists, and environmental health professionals through the principles of molecular and biochemical toxicology and the complex mechanisms of toxicity. Whether it's used in the classroom or in industry, research, or academia, this book is essential for anyone interested in understanding the molecular mechanisms through which toxicants produce adverse effects.
Author : Ryūichi Katō
Publisher : Taylor & Francis
ISBN 13 : 9780850667370
Total Pages : 612 pages
Book Rating : 4.6/5 (673 download)
Download or read book Xenobiotic Metabolism and Disposition written by Ryūichi Katō and published by Taylor & Francis. This book was released on 1989 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: Papers of the May, 1988 meeting. They provide an overview of recent research and current theory in the field. Topics include the molecular biology and multiplicity of cytochrome P-450; non-P-450 enzymes; drug design and delivery; stereochemical aspects; characteristics of drug metabolism in humans;
Author : Usha Varanasi
Publisher : CRC Press
ISBN 13 : 9780849368448
Total Pages : 360 pages
Book Rating : 4.3/5 (684 download)
Download or read book Metabolism of Polycyclic Aromatic Hydrocarbons in the Aquatic Environment written by Usha Varanasi and published by CRC Press. This book was released on 1989-03-31 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book shows how the biological transport, bioaccumulation, disposition, and toxicity of polycyclic aromatic hydrocarbons (PAH) in the aquatic environment are influenced by the ability or inability of organisms to metabolize these environmental pollutants. Written by leading scientists in the fields of PAH metabolism and toxicity in both aquatic and mammalian systems, this book discusses recent advances in the areas of PAH biogeochemistry and bioaccumulation, microbial degradation, enzymes of activation, and detoxication, metabolism of PAH, and laboratory and field studies on carcinogenic/toxic effects. Additionally, important similarities and differences in metabolism of PAH by aquatic and terrestrial organisms are featured. The discussion of bioavailability, metabolism, and subsequent toxic effects should aid in the assessment of the ecological consequences of PAH in the aquatic environment.
Author : D.J. Smith
Publisher : Springer Science & Business Media
ISBN 13 : 1461547032
Total Pages : 226 pages
Book Rating : 4.4/5 (615 download)
Download or read book Xenobiotics in Fish written by D.J. Smith and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aquaculture is rapidly becoming a major source of fish protein used to meet the nutritional needs of humans. As the aquaculture industry grows, exposure of farmed fish to environmental contaminants, and the need for chemical therapeutic agents for fish, will increase. This book is designed to bring together authorities worldwide on the regulation of environmental contaminants and food chemicals and researchers investigating the metabolism and disposition of foreign chemicals (xenobiotics) in fish species.
Author :
Publisher :
ISBN 13 :
Total Pages : 1520 pages
Book Rating : 4.E/5 ( download)
Download or read book Environmental Health Perspectives written by and published by . This book was released on 2000 with total page 1520 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Yasmin Singh
Publisher :
ISBN 13 :
Total Pages : 334 pages
Book Rating : 4.:/5 (47 download)
Download or read book The Role of Xenobiotic Metabolism and Lipid Peroxidation in Hepatotoxicity in the Rat and Trout written by Yasmin Singh and published by . This book was released on 1991 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kristine L. Willett
Publisher : CRC Press
ISBN 13 : 1003825265
Total Pages : 1118 pages
Book Rating : 4.0/5 (38 download)
Download or read book Toxicology of Fishes written by Kristine L. Willett and published by CRC Press. This book was released on 2024-02-06 with total page 1118 pages. Available in PDF, EPUB and Kindle. Book excerpt: This up-to-date, comprehensive toxicology handbook is devoted to the effects of environmental pollution on fish. Fish species represent nearly half of all vertebrates and have become important sentinels for environmental contamination and model organisms for understanding adverse outcomes from exposures. This new edition is written by recognized experts, and it highlights the significant research progress in fish toxicology that has resulted from rapid technological developments in analytical, biochemical, and genomic sciences. The book: Discusses fundamental topics such as toxicokinetics in fishes, processes governing biotransformation within these organisms, and reactive oxygen species and oxidative stress. Explains key target organ systems for chemical impacts in fish, such as the nervous and immune systems, and how fishes can develop resistance to chemical toxicity. Covers multi-transgenerational effects on fishes, epigenetics, proteomics and metabolomics, and adverse outcome pathways. Replacing the case studies in the first edition, this update delves into the impacts of microplastics, pharmaceuticals, and oil spills in dedicated final chapters. With nearly 200 illustrations and tables, this comprehensive reference work presents concepts in a way that is useful for both novices to and experts in the field of fish toxicology.
Author : Stefan Nilsson
Publisher : Springer Science & Business Media
ISBN 13 : 9401165580
Total Pages : 208 pages
Book Rating : 4.4/5 (11 download)
Download or read book Fish Physiology: Recent Advances written by Stefan Nilsson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fishes are very successful vertebrates and have adapted to a wide range of environmental conditions, from the deep ocean to the smallest brook or pond. The physiological background to these environmental adaptations is, obviously, far from clear, and provides fish physiologists with many challenges. The number of extant fish species has been estimated to be in excess of 20000, and only relatively few of these have been subject to physiological studies. Yet among these animals can be found many physiological systems different from those of the land-dwelling vertebrates, and also systems similar to those of the 'higher' vertebrates but at a different level of phylogenetic development. Apart from the rapidly increasing interest in basic fish physi ology, the last few years have seen a dramatic increase in applied research, aimed primarily in two directions: fish culture and envi ronmental toxicology. Physiological research is of vital importance in both these fields, and basic fish physiology is a necessary base for the applied research. This book is intended for a wide readership among senior undergraduate, postgraduate and research students, as well as uni versity teachers and researchers in zoology, physiology, aqua culture and biology generally. The book focuses on five major areas of basic and applied research: haemopoiesis, acid-base regu lation, circulation, gastro-intestinal functions and physiological toxicology. The chapters will serve as introductions to these fields, as well as up-to-date reviews of the most recent advances in the research areas.
Author : Gisela H. Degen
Publisher : Springer
ISBN 13 : 9783642794537
Total Pages : 0 pages
Book Rating : 4.7/5 (945 download)
Download or read book Toxicology in Transition written by Gisela H. Degen and published by Springer. This book was released on 2011-12-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volume contains the main papers presented at the 1994 EUROTOX Congress, Basel, Switzerland, August 21-24, 1994. Toxicology has become a less descriptive science because more importance has been placed on the mechanisms underlying toxic effects. This is reflected in symposia and workshops devoted to species differences in organ toxicity, receptor-mediated toxicity and stereochemical effects of xenobiotics. Recent progress in the fields of immunotoxicology, ecotoxicology, and neurotoxicology is highlighted and documented together with the present discussion on harmonized regulatory guidelines.
Author :
Publisher :
ISBN 13 :
Total Pages : 1064 pages
Book Rating : 4.:/5 (319 download)
Download or read book Biomedical Index to PHS-supported Research: pt. A. Subject access A-H written by and published by . This book was released on 1992 with total page 1064 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 828 pages
Book Rating : 4.F/5 ( download)
Download or read book Environmental Toxicology and Chemistry written by and published by . This book was released on 2006 with total page 828 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Richard T. Di Giulio
Publisher : CRC Press
ISBN 13 : 0203647297
Total Pages : 1102 pages
Book Rating : 4.2/5 (36 download)
Download or read book The Toxicology of Fishes written by Richard T. Di Giulio and published by CRC Press. This book was released on 2008-02-25 with total page 1102 pages. Available in PDF, EPUB and Kindle. Book excerpt: When looking for a book on fish toxicology, you might find one that discusses the biochemical and molecular aspects, or one that focuses aquatic toxicology in general. You can find resources that cover human and animal toxicology or ecotoxicology in general, but no up-to-date, comprehensive monograph devoted to the effects of chemical pollution on
Author : European Association for Veterinary Pharmacology and Toxicology. Congress
Publisher :
ISBN 13 :
Total Pages : 492 pages
Book Rating : 4.3/5 (21 download)
Download or read book Proceedings of the 5th Congress of the European Association for Veterinary Pharmacology and Toxicology written by European Association for Veterinary Pharmacology and Toxicology. Congress and published by . This book was released on 1991 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Carey N. Pope
Publisher : Academic Press
ISBN 13 : 0128136030
Total Pages : 646 pages
Book Rating : 4.1/5 (281 download)
Download or read book An Introduction to Interdisciplinary Toxicology written by Carey N. Pope and published by Academic Press. This book was released on 2020-02-18 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Interdisciplinary Toxicology: From Molecules to Man integrates the various aspects of toxicology, from "simple molecular systems, to complex human communities, with expertise from a spectrum of interacting disciplines. Chapters are written by specialists within a given subject, such as a chemical engineer, nutritional scientist, or a microbiologist, so subjects are clearly explained and discussed within the toxicology context. Many chapters are comparative across species so that students in ecotoxicology learn mammalian toxicology and vice versa. Specific citations, further reading, study questions, and other learning features are also included. The book allows students to concurrently learn concepts in both biomedical and environmental toxicology fields, thus better equipping them for the many career opportunities toxicology provides. This book will also be useful to those wishing to reference how disciplines interact within the broad field of toxicology. - Covers major topics and newer areas in toxicology, including nanotoxicology, Tox21, epigenetic toxicology, and organ-specific toxicity - Includes a variety of perspectives to give a complete understanding of toxicology - Written by specialists within each subject area, e.g., a chemical engineer, to ensure concepts are clearly explained
Author : Peter G. Wells
Publisher : CRC Press
ISBN 13 : 1351431447
Total Pages : 716 pages
Book Rating : 4.3/5 (514 download)
Download or read book Microscale Testing in Aquatic Toxicology written by Peter G. Wells and published by CRC Press. This book was released on 2018-05-04 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioassays are among the ecotoxicologist's most effective weapons in the evaluation of water quality and the assessment of ecological impacts of effluents, chemicals, discharges, and emissions on the aquatic environment. Information on these assessment aids is needed throughout the international scientific and environmental management community. This comprehensive reference provides an excellent overview of the small-scale aquatic bioassay techniques and applications currently in use around the world. This special volume is the result of several years of collaboration between Environment Canada and Fisheries and Oceans Canada. Internationally recognized research scientists at many institutions have contributed to this state-of-the-art examination of the exciting, environmentally important field of microscale testing in aquatic toxicology. Microscale Testing in Aquatic Toxicology contains over forty chapters covering relevant principles, new techniques and recent advancements, and applications in scientific research, environmental management, academia, and the private sector.
