Regulation of Interleukin-2 Gene Transcription in CD8 Positive Cells

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Publisher :
ISBN 13 :
Total Pages : 208 pages
Book Rating : 4.:/5 (449 download)

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Book Synopsis Regulation of Interleukin-2 Gene Transcription in CD8 Positive Cells by : Rosalynde J. Finch

Download or read book Regulation of Interleukin-2 Gene Transcription in CD8 Positive Cells written by Rosalynde J. Finch and published by . This book was released on 2000 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Interleukin-2 and the Regulation of CD8 T Cell Responses

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (545 download)

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Book Synopsis Interleukin-2 and the Regulation of CD8 T Cell Responses by : Warren Noel D'Souza

Download or read book Interleukin-2 and the Regulation of CD8 T Cell Responses written by Warren Noel D'Souza and published by . This book was released on 2003 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Interleukin 2

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Publisher : Academic Press
ISBN 13 :
Total Pages : 346 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Interleukin 2 by : Kendall A Smith

Download or read book Interleukin 2 written by Kendall A Smith and published by Academic Press. This book was released on 1988-09-28 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interleukin 2 focuses on interleukin 2 (IL-2) and its impact on immunology. Topics covered include IL-2's mechanism of action, the structure of the IL-2 receptor, the characteristics of natural and recombinant human IL-2, regulation of IL-2 production by the T cell antigen receptor, how IL-2 binding induces the transcription of a novel set of genes, and the pathological roles of IL-2 receptor inducers in adult T cell leukemia. This book is comprised of 12 chapters and begins with a historical overview of IL-2, from the discovery of soluble mitogenic factors in culture media of stimulated lymphocytes to the discovery of IL-2 as the molecule responsible for stimulating T cell proliferation. The physicochemical and biological properties of purified recombinant IL-2 are then described, paying particular attention to natural IL-2 derived from human peripheral blood leukocytes. The chapters that follow discuss the different techniques used to gain insight into the functionally important regions of IL-2, the role of the T cell antigen receptor in regulating the production of IL-2, and the structure of the human high-affinity IL-2 receptor. The book also describes transmembrane signaling by IL-2, IL-2-inducible gene expression in T lymphocytes, abnormal IL-2 receptor expression in adult T cell leukemia, the use of IL-2 receptors in immunosuppressive therapy, and the use of IL-2 as a pharmacologic reagent. This book will be of interest to students and researchers in immunology and biochemistry.

Interleukin-12 and Interferon-[alpha]/[beta] - Mediated Gene Regulation in Programming CD8+ T Cell Differentiation

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ISBN 13 :
Total Pages : 522 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Interleukin-12 and Interferon-[alpha]/[beta] - Mediated Gene Regulation in Programming CD8+ T Cell Differentiation by : Pujya Agarwal

Download or read book Interleukin-12 and Interferon-[alpha]/[beta] - Mediated Gene Regulation in Programming CD8+ T Cell Differentiation written by Pujya Agarwal and published by . This book was released on 2007 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Interleukin-2 and the Regulation of CD8 T Cell Responses

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Publisher :
ISBN 13 :
Total Pages : 324 pages
Book Rating : 4.:/5 (545 download)

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Book Synopsis Interleukin-2 and the Regulation of CD8 T Cell Responses by : Warren Noel D'Souza

Download or read book Interleukin-2 and the Regulation of CD8 T Cell Responses written by Warren Noel D'Souza and published by . This book was released on 2003 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Interleukin-2 Dependent STAT5 Activation Drives Regulatory T Cell Development

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Publisher :
ISBN 13 :
Total Pages : 346 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Interleukin-2 Dependent STAT5 Activation Drives Regulatory T Cell Development by : Matthew Alan Burchill

Download or read book Interleukin-2 Dependent STAT5 Activation Drives Regulatory T Cell Development written by Matthew Alan Burchill and published by . This book was released on 2007 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Regulation of Interleukin-2 Gene Expression by the Cellular Protein, Interleukin Enhancer Binding Factor

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ISBN 13 :
Total Pages : 282 pages
Book Rating : 4.:/5 (413 download)

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Book Synopsis Regulation of Interleukin-2 Gene Expression by the Cellular Protein, Interleukin Enhancer Binding Factor by : Ajay Nirula

Download or read book Regulation of Interleukin-2 Gene Expression by the Cellular Protein, Interleukin Enhancer Binding Factor written by Ajay Nirula and published by . This book was released on 1997 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cooperation of Liver Cells in Health and Disease

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Publisher : Springer Science & Business Media
ISBN 13 : 3642565530
Total Pages : 154 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Cooperation of Liver Cells in Health and Disease by : Z. Kmiec

Download or read book Cooperation of Liver Cells in Health and Disease written by Z. Kmiec and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is only during the last decade that the functions of sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes have been better understood. The development of methods for isolation and co-culturing various types of liver cells has established that they communicate and cooperate via secretion of various intercellular mediators. This monograph summarizes multiple data that suggest the important role of cellular cross-talk for the functions of both normal and diseased liver. Special features of the book include concise presentation of the majority of detailed data in 19 tables. Original schemes allow for the clear illustration of complicated intercellular relationships. This is the first ever presentation of the newly emerging field of liver biology, which is important for hepatic function in health and disease and opens new avenues for therapeutic interventions.

Signaling Mechanisms Regulating T Cell Diversity and Function

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Publisher : CRC Press
ISBN 13 : 149870509X
Total Pages : 258 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Signaling Mechanisms Regulating T Cell Diversity and Function by : Jonathan Soboloff

Download or read book Signaling Mechanisms Regulating T Cell Diversity and Function written by Jonathan Soboloff and published by CRC Press. This book was released on 2017-03-27 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.

The Role of CD28 in T Cell Activation and the Transcriptional Regulation of the Interleukin-2 Gene

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (596 download)

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Book Synopsis The Role of CD28 in T Cell Activation and the Transcriptional Regulation of the Interleukin-2 Gene by : Christine Edmead

Download or read book The Role of CD28 in T Cell Activation and the Transcriptional Regulation of the Interleukin-2 Gene written by Christine Edmead and published by . This book was released on 1996 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Transcriptional Regulation of Interleukin-2 Gene Expressio Through NF-kB and RW-BF

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Publisher :
ISBN 13 :
Total Pages : 260 pages
Book Rating : 4.:/5 (182 download)

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Book Synopsis Transcriptional Regulation of Interleukin-2 Gene Expressio Through NF-kB and RW-BF by : Beatrice Hoyos

Download or read book Transcriptional Regulation of Interleukin-2 Gene Expressio Through NF-kB and RW-BF written by Beatrice Hoyos and published by . This book was released on 1993 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Suppression and Regulation of Immune Responses

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Publisher : Humana
ISBN 13 : 9781493931385
Total Pages : 0 pages
Book Rating : 4.9/5 (313 download)

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Book Synopsis Suppression and Regulation of Immune Responses by : Maria Cristina Cuturi

Download or read book Suppression and Regulation of Immune Responses written by Maria Cristina Cuturi and published by Humana. This book was released on 2015-11-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second volume expands upon the previous edition with new research and objectives in immunoregulation and immune tolerance. Chapters cover topics ranging from new molecular and cellular mechanisms of tolerance; generation and characterization of mice regulatory macrophages; recent advances in the treatment of immune-mediated inflammatory disorders; and novel mechanisms and therapeutic perspectives on food allergies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Suppression and Regulation of Immune Responses: Methods and Protocols, Volume II is a great resource for current research and inspiration for new studies in immune tolerance.

CD4+CD25+ Regulatory T Cells: Origin, Function and Therapeutic Potential

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Publisher : Springer Science & Business Media
ISBN 13 : 3540277021
Total Pages : 331 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis CD4+CD25+ Regulatory T Cells: Origin, Function and Therapeutic Potential by : B. Kyewski

Download or read book CD4+CD25+ Regulatory T Cells: Origin, Function and Therapeutic Potential written by B. Kyewski and published by Springer Science & Business Media. This book was released on 2006-01-09 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: The vertebrate immune system defends the organism against invading pathogens while at the same time being self-tolerant to the body’s own constituents thus preserving its integrity. Multiple mechanisms work in concert to ensure self-tolerance. Apart from purging the T cell repertoire from auto-reactive T cells via negative selection in the thymus dominant tolerance exerted by regulatory T cells plays a major role in tolerance imposition and maintenance. Among the various regulatory/suppressive cells hitherto described, CD4+CD25+ regulatory T cells (Treg) and interleukin-10 producing T regulatory 1 (Tr1) cells have been studied in most detail and are the subject of most articles in this issue. Treg, also called "natural" regulatory T cells, will be traced from their intra-thymic origin to the site of their action in peripheral lymphoid organs and tissues. The repertoire of Treg is clearly biased towards recognition of self-antigens, thereby potentially preventing autoimmune diseases such as gastritis and oophoritis. Regulatory T cells, however also control infections, allergies and tolerance to transplanted tissues and this requires their induction in the periphery under conditions which are not yet fully understood. The concept of dominant tolerance, by far not novel, will offer new insights and hopefully tools for the successful treatment of autoimmune diseases, improved cancer immunotherapy and transplant survival. The fulfillment of these high expectations will, however, require their unambiguous identification and a better understanding of their mode of action.

Calcium Entry Channels in Non-Excitable Cells

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Publisher : CRC Press
ISBN 13 : 149875273X
Total Pages : 343 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Calcium Entry Channels in Non-Excitable Cells by : Juliusz Ashot Kozak

Download or read book Calcium Entry Channels in Non-Excitable Cells written by Juliusz Ashot Kozak and published by CRC Press. This book was released on 2017-07-14 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the molecular identification of store-operated calcium channels which were reviewed by earlier volumes in the Methods in Signal Transduction series. Crystallographic and pharmacological approaches to the study of calcium channels of epithelial cells are also discussed. Calcium ion is a messenger in most cell types. Whereas voltage gated calcium channels have been studied extensively, the non-voltage gated calcium entry channel genes have only been identified relatively recently. The book will fill this important niche.

Interleukin-10 in Health and Disease

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Publisher : Springer
ISBN 13 : 366243492X
Total Pages : 244 pages
Book Rating : 4.6/5 (624 download)

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Book Synopsis Interleukin-10 in Health and Disease by : Simon Fillatreau

Download or read book Interleukin-10 in Health and Disease written by Simon Fillatreau and published by Springer. This book was released on 2014-07-08 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a set of reviews dedicated to the biology of Interleukin (IL)-10. It includes chapters on its importance for maintaining immune homeostasis in humans, its role in intestinal immunity and its functions during viral and bacterial infections. In addition, it presents reviews on the mechanisms linking innate microbial recognition to the production of IL-10 and on how IL-10 recognition by its receptor functions. The roles of T and B cells as relevant sources of IL-10 are also discussed, with an emphasis on the clinical opportunities offered by IL-10-producing Tr1 cells for the suppression of unwanted immunity. Finally, the functions of other cytokines of the IL-10 family are presented. Collectively, these articles provide a comprehensive overview of our current knowledge on one of the most important anti-inflammatory cytokines known to date.

Molecular Biology of the Cell

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ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Persistent Viral Infections

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Publisher : Wiley-Blackwell
ISBN 13 :
Total Pages : 754 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Persistent Viral Infections by : R. Ahmed

Download or read book Persistent Viral Infections written by R. Ahmed and published by Wiley-Blackwell. This book was released on 1999 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt: Persistent Viral Infections Edited by Rafi Ahmed Emory Vaccine Center, Atlanta, USA and Irvin S. Y. Chen UCLA School of Medicine, Los Angeles, USA During the past decade much of our attention has focused on diseases associated with viral persistence. Major breakthroughs in immunology, and the advent of molecular approaches to study pathogenesis have increased our understanding of the complex virus-host interactions that occur during viral persistence. Persistent Viral Infections focuses on: * The pathogenesis and immunology of chronic infections * Animal models that provide, or have the potential to provide, major insights This volume will be essential reading for virologists, immunologists, oncologists and neurologists.