Recent Progresses In Amebiasis

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Recent Progresses in Amebiasis

Author : Anjan Debnath
Publisher : Frontiers Media SA
ISBN 13 : 2889630064
Total Pages : 415 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Recent Progresses in Amebiasis by : Anjan Debnath

Download or read book Recent Progresses in Amebiasis written by Anjan Debnath and published by Frontiers Media SA. This book was released on 2019-10-14 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amebiasis, a parasitic disease transmitted by the unicellular protozoan parasite Entamoeba histolytica, is the cause of at least 100,000 deaths each year. The disease is mostly prevalent in developing countries and is one of the three common causes of death from parasitic diseases. The parasite has two stages in its life cycle in the host: the infective cyst and the invasive trophozoite. In the large intestine, the parasite feeds on bacteria and on cellular debris. No vaccine against amebiasis currently exists. Although metronidazole is the drug of choice for treating amebiasis, adverse effects in patients and potential resistance to metronidazole in other protozoa exist. About nine out of 10 people who are infected with E. histolytica are asymptomatic and in those individuals who develop symptoms, bloody diarrhea (amebic colitis) and liver abscess are the most common symptoms. One possible explanation for this observation is the difference in the gut microbiota between individuals that may significantly influence the host’s immune response in amebiasis and E. histolytica's virulence. Amebiasis is characterized by acute inflammation of the intestine with release of pro-inflammatory cytokines, reactive oxygen species and reactive nitrogen species from activated cells of the host's immune system. In recent years, significant advances on the cell biology of Entamoeba infection have been achieved through the development of new genetic tools to manipulate gene expression in the parasite and through the application of Omics tools. In this Research Topic, we welcome high quality original research articles, as well as review, opinion or method articles, on amebiasis including but not limited to the regulation of gene expression, cell biology and signaling, adaptation and resistance to environmental stresses, metabolism, pathogenesis and immunity, pathogenesis and microbiome, drug discovery and drug resistance.

Amebiasis

Author : Tomoyoshi Nozaki
Publisher : Springer
ISBN 13 : 4431552006
Total Pages : 567 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Amebiasis by : Tomoyoshi Nozaki

Download or read book Amebiasis written by Tomoyoshi Nozaki and published by Springer. This book was released on 2014-12-05 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book documents and presents new developments in the study of amebiasis, one of the neglected tropical diseases. Nearly 50 million people worldwide are infected with the pathogen Entamoeba histolytica, causing large-scale morbidity and mortality particularly in developing countries. This book will help clinicians for better diagnosis and management of the disease, researchers for initiating research projects on some of the poorly understood aspects of the disease and the pathogen, and students for updating their knowledge. The subjects covered range from genomics and molecular and cell biology to drug resistance and new drug development, highlighting major advances in recent years in our understanding due to rapid progress in genomic and other biomedical technologies, such as visualization of molecular processes. Most of the chapters provide recent information based on latest publications. A few chapters describe some of the critical methodological issues that will be helpful for students and researchers interested in getting into the field. The contributing authors include almost all the active researchers and clinicians from around the world. This book will be a useful primary material and a valuable source of information for anyone interested in understanding amebiasis, its diagnosis, and treatment. It will also be useful to those who are interested in learning about the biology of early branching eukaryotes and protist pathogens.

American Academy of Pediatrics Textbook of Pediatric Care

Author : Jane Meschan Foy
Publisher :
ISBN 13 : 9781581109665
Total Pages : 0 pages
Book Rating : 4.1/5 (96 download)

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Book Synopsis American Academy of Pediatrics Textbook of Pediatric Care by : Jane Meschan Foy

Download or read book American Academy of Pediatrics Textbook of Pediatric Care written by Jane Meschan Foy and published by . This book was released on 2016-03-31 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive manual of pediatric medicine - completely updated with 75 new chapters and e-book access.

Liver Pathophysiology

Author : Pablo Muriel
Publisher : Academic Press
ISBN 13 : 0128043210
Total Pages : 914 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Liver Pathophysiology by : Pablo Muriel

Download or read book Liver Pathophysiology written by Pablo Muriel and published by Academic Press. This book was released on 2017-03-02 with total page 914 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liver Pathophysiology: Therapies and Antioxidants is a complete volume on morphology, physiology, biochemistry, molecular biology and treatment of liver diseases. It uses an integral approach towards the role of free radicals in the pathogenesis of hepatic injury, and how their deleterious effects may be abrogated by the use of antioxidants. Written by the most prominent authors in the field, this book will be of use to basic and clinical scientists and clinicians working in the biological sciences, especially those dedicated to the study and treatment of liver pathologies. Presents the most recent advances in hepatology, with a special focus on the role of oxidative stress in liver injury. Provides in vivo and in vitro models to study human liver pathology. Explains the beneficial effects of antioxidants on liver diseases. Contains the most recent and modern treatments of hepatic pathologies, including, but not limited to, stem cells repopulation, gene therapy and liver transplantation.

Amebiasis

Author : Jonathan I. Ravdin
Publisher : World Scientific Publishing Company
ISBN 13 : 9781860941337
Total Pages : 186 pages
Book Rating : 4.9/5 (413 download)

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Book Synopsis Amebiasis by : Jonathan I. Ravdin

Download or read book Amebiasis written by Jonathan I. Ravdin and published by World Scientific Publishing Company. This book was released on 2000 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: "an excellent introduction to a fascinating, baffling and still medically extremely significant parasite".Transactions of the Royal Society of Tropical Medicine and Hygiene, 2000

Drug Development for Parasite-induced Diarrheal Diseases

Author : Anjan Debnath
Publisher : Frontiers Media SA
ISBN 13 : 2889452484
Total Pages : 179 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Drug Development for Parasite-induced Diarrheal Diseases by : Anjan Debnath

Download or read book Drug Development for Parasite-induced Diarrheal Diseases written by Anjan Debnath and published by Frontiers Media SA. This book was released on 2017-08-25 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the top four contributors to the global burden of disease is diarrheal infections. Intestinal parasites are major causes of morbidity and mortality associated with diarrheal diseases in both the developed and developing world. Amebiasis is responsible for 50 million cases of invasive disease and 70,000 deaths annually in the world. Giardiasis has an estimated worldwide prevalence of 280 million cases annually. In developed countries, Giardia lamblia infects about 2% of adults and 6-8% of children. The prevalence of G. lamblia infection is generally higher in developing countries, ranging from 3% to 90%. Furthermore, giardial infections contribute substantially to the 2.5 million annual deaths from diarrheal disease. In Asia, Africa, and Latin America, about 500,000 new giardiasis cases are reported each year. Cryptosporidium accounts for 20% and 9% of diarrheal episodes in children in developing and developed countries, respectively. Infection with Cryptosporidium can be chronic and especially debilitating in immunosuppressed individuals and malnourished children. A recent study to measure disease burden, based on disability-adjusted life years (DALYs), found that cryptosporidiosis and amebiasis produce about 10.6 million DALYs. This exceeds the DALYs of any helminth infection currently being targeted by the World Health Organization for preventive chemotherapy. Because of its link with poverty, Giardia and Cryptosporidium were included in the WHO Neglected Diseases Initiative in 2004. E. histolytica, G. lamblia, and C. parvum have been listed by the National Institutes of Health (NIH) as category B priority biodefense pathogens due to low infectious dose and potential for dissemination through compromised food and water supplies in the United States. Despite the prevalence of amebiasis, giardiasis, and cryptosporidiosis there are no vaccines or prophylactic drugs. The first-line drugs for invasive amebiasis and giardiasis chemotherapy are nitroimidazoles, with the prototype, metronidazole, being the most common drug used worldwide. Metronidazole has been shown to be both mutagenic in a microbiological system and carcinogenic to rodents, and frequently causes gastrointestinal side effects. In spite of the efficacy of nitroimidazole drugs, treatment failures in giardiasis occur in up to 20% of cases. Clinical resistance of G. lamblia to metronidazole is proven and cross resistance is a concern with all commonly used antigiardial drugs. Nitazoxanide, the only FDA-approved drug for the treatment of cryptosporidiosis, is effective in the treatment of immunocompetent patients and partially effective for immunosuppressed patients. Therefore, it is critical to search for more effective drugs to treat amebiasis, giardiasis, and cryptosporidiosis. This Research Topic for Frontiers in Microbiology will explore the recent progress in drug development for parasitic diarrheal diseases. This includes an understanding of drug resistance mechanisms. We would also welcome submissions on the drug development for other diarrheal parasites. We hope that this research topic will include a comprehensive survey of various attempts by the parasitology research community to create effective drugs for these diseases.

Foodborne Parasites

Author : Ynes R. Ortega
Publisher : Springer Science & Business Media
ISBN 13 : 0387311971
Total Pages : 301 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Foodborne Parasites by : Ynes R. Ortega

Download or read book Foodborne Parasites written by Ynes R. Ortega and published by Springer Science & Business Media. This book was released on 2006-11-22 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the two major parasite groups that are transmitted via water or foods: the single-celled protozoa, and the helminths: cestodes (tapeworms), nematodes (round worms), and trematodes (flukes). Each chapter covers the biology, mechanisms of pathogenesis, epidemiology, treatment, and inactivation of these parasites. This important new text offers a better understanding of the biology and control of parasitic infections necessary to reduce or eliminate future outbreaks in the U.S. and elsewhere.

Amebiasis

Author : Roberto R. Kretschmer
Publisher : CRC Press
ISBN 13 : 1000083624
Total Pages : 356 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Amebiasis by : Roberto R. Kretschmer

Download or read book Amebiasis written by Roberto R. Kretschmer and published by CRC Press. This book was released on 2020-03-26 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1990, this book offers a full, comprehensive guide to the process of amebiasis. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for students of medicine, and other practitioners in their respective fields.

Recent Progress in Slow Sand and Alternative Biofiltration Processes

Author : Rolf Gimbel
Publisher : IWA Publishing
ISBN 13 : 1843391201
Total Pages : 580 pages
Book Rating : 4.8/5 (433 download)

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Book Synopsis Recent Progress in Slow Sand and Alternative Biofiltration Processes by : Rolf Gimbel

Download or read book Recent Progress in Slow Sand and Alternative Biofiltration Processes written by Rolf Gimbel and published by IWA Publishing. This book was released on 2006-03-31 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: Slow sand filtration is typically cited as being the first "engineered" process in drinking-water treatment. Proven modifications to the conventional slow sand filtration process, the awareness of induced biological activity in riverbank filtration systems, and the growth of oxidant-induced biological removals in more rapid-rate filters (e.g. biological activated carbon) demonstrate the renaissance of biofiltration as a treatment process that remains viable for both small, rural communities and major cities. Biofiltration is expected to become even more common in the future as efforts intensify to decrease the presence of disease-causing microorganisms and disinfection by-products in drinking water, to minimize microbial regrowth potential in distribution systems, and where operator skill levels are emphasized. Recent Progress in Slow Sand and Alternative Biofiltration Processes provides a state-of-the-art assessment on a variety of biofiltration systems from studies conducted around the world. The authors collectively represent a perspective from 23 countries and include academics, biofiltration system users, designers, and manufacturers. It provides an up-to-date perspective on the physical, chemical, biological, and operational factors affecting the performance of slow sand filtration (SSF), riverbank filtration (RBF), soil-aquifer treatment (SAT), and biological activated carbon (BAC) processes. The main themes are: comparable overviews of biofiltration systems; slow sand filtration process behavior, treatment performance and process developments; and alternative biofiltration process behaviors, treatment performances, and process developments.

Paniker's Textbook of Medical Parasitology

Author : C. K. Jayaram Paniker
Publisher : JP Medical Ltd
ISBN 13 : 9352701860
Total Pages : 278 pages
Book Rating : 4.3/5 (527 download)

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Book Synopsis Paniker's Textbook of Medical Parasitology by : C. K. Jayaram Paniker

Download or read book Paniker's Textbook of Medical Parasitology written by C. K. Jayaram Paniker and published by JP Medical Ltd. This book was released on 2017-09-14 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of this textbook is a complete guide to parasitology for undergraduate medical students. Divided into 23 chapters, each topic has been thoroughly updated and expanded to cover the most recent advances and latest knowledge in the field. The book begins with an overview of parasitology, then discusses numerous different types of parasite, concluding with a chapter on diagnosis methods. Many chapters have been rewritten and the eighth edition of the book features many new tables, flow charts and photographs. Each chapter concludes with a ‘key points’ box to assist with revision. Key points Eighth edition providing undergraduates with a complete guide to parasitology Fully revised text with many new topics, tables and photographs Each chapter concludes with ‘key points’ box to assist revision Previous edition (9789350905340) published in 2013

Oxidative Stress in Microbial Diseases

Author : Sajal Chakraborti
Publisher : Springer
ISBN 13 : 9789811387623
Total Pages : 0 pages
Book Rating : 4.3/5 (876 download)

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Book Synopsis Oxidative Stress in Microbial Diseases by : Sajal Chakraborti

Download or read book Oxidative Stress in Microbial Diseases written by Sajal Chakraborti and published by Springer. This book was released on 2019-11-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses recent advances in our understanding of the role of oxidants in microbial pathophysiology, providing valuable insights into the complex role of reactive oxygen species (ROS) in host-microbial interactions. The various chapters take readers through the function of ROS in infections ranging from viral to bacterial, and describe how microorganisms have developed complex strategies to not only avoid contact with phagocyte-derived oxidants, but also protect themselves from injury when oxidants are encountered. Featuring the latest research in the field of microbial diseases, this timely book is a ready reference for scientists looking to develop new anti-microbial drugs.

Bench aids for the diagnosis of intestinal parasites

Author : World Health Organization
Publisher : World Health Organization
ISBN 13 : 9241515341
Total Pages : 32 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Bench aids for the diagnosis of intestinal parasites by : World Health Organization

Download or read book Bench aids for the diagnosis of intestinal parasites written by World Health Organization and published by World Health Organization. This book was released on 2019-09-02 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of Bench aids for the diagnosis of intestinal parasites is intended both as a practical tool for the diagnosis of intestinal parasitic infections for laboratory and field workers and as a teaching aid for students and trainees. The plates are arranged on two sides: the recto with microphotographs for the identification of eggs larvae trophozoites cysts and oocysts occurring in faeces and the verso dedicated to the different copromicroscopical methods (procedures) and main staining techniques used in parasitology. Special attention has been devoted to all graphical and pictorial contents. The decision to include the outline of an Ascaris lumbricoides egg in its relative size next to each parasitic structure fulfils the intention of visualizing the actual dimensions that the eye needs to be looking for when examining the specimens with a microscope. For each image the size of the parasite and a short description are provided to assist in the microscopical identification. Two summary plates one for helminths and the other for protozoa are also included to provide a visual overview of the different presentations of parasitic elements. The bench aids have been produced in a weatherproof plastic-sealed format that is robust and easy to use at the bench. They are recommended for use by all health workers engaged in the routine diagnosis of intestinal parasitic infections.

The Amoebae Living in Man

Author : Clifford Dobell
Publisher :
ISBN 13 :
Total Pages : 182 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Amoebae Living in Man by : Clifford Dobell

Download or read book The Amoebae Living in Man written by Clifford Dobell and published by . This book was released on 1919 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Prevention and Control of Intestinal Parasitic Infections

Author : WHO Expert Committee on Prevention and Control of Intestinal Parasitic Infections
Publisher :
ISBN 13 :
Total Pages : 92 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Prevention and Control of Intestinal Parasitic Infections by : WHO Expert Committee on Prevention and Control of Intestinal Parasitic Infections

Download or read book Prevention and Control of Intestinal Parasitic Infections written by WHO Expert Committee on Prevention and Control of Intestinal Parasitic Infections and published by . This book was released on 1987 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Recent Advances in Pediatrics - Special Volume 23 - Pediatric Gastroenterology, Hepatology and Nutrition

Author : Suraj Gupte
Publisher : JP Medical Ltd
ISBN 13 : 9350904489
Total Pages : 456 pages
Book Rating : 4.3/5 (59 download)

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Book Synopsis Recent Advances in Pediatrics - Special Volume 23 - Pediatric Gastroenterology, Hepatology and Nutrition by : Suraj Gupte

Download or read book Recent Advances in Pediatrics - Special Volume 23 - Pediatric Gastroenterology, Hepatology and Nutrition written by Suraj Gupte and published by JP Medical Ltd. This book was released on 2013-06-30 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Special Volume 23 of Recent Advances in Pediatrics is a compilation of reviews bringing trainees and physicians fully up to date with key developments in paediatric gastroenterology, hepatology and nutrition. Divided into four sections, Part 1 discusses issues in paediatric gastroenterology such as irritable bowel syndrome, celiac disease, abdominal pain and gastrointestinal endoscopy. Part 2 examines hepatologic disorders that may be encountered in children, including acute liver failure, viral hepatitis and liver transplantation. Parts 3 and 4 cover nutrition and pharmacotherapy. Presented in an easy to follow format, Special Volume 23 follows a multidisciplinary approach. Each chapter finishes with a summary of key learning points and extensive references for further reading. Clinical photographs, illustrations and tables enhance learning. Key points New, updated volume presenting latest developments in paediatric gastroenterology, hepatology and nutrition Multidisciplinary approach, easy to follow format Extensive references and key learning points summarised in each chapter Includes contributions from experts in London, Liverpool and California

Red Book Atlas of Pediatric Infectious Diseases

Author : American Academy of Pediatrics
Publisher :
ISBN 13 : 9781581102475
Total Pages : 440 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Red Book Atlas of Pediatric Infectious Diseases by : American Academy of Pediatrics

Download or read book Red Book Atlas of Pediatric Infectious Diseases written by American Academy of Pediatrics and published by . This book was released on 2007 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on key content from Red Book: 2006 Report of the Committee on Infectious Diseases, 27th Edition, the new Red Bookr Atlas is a useful quick reference tool for the clinical diagnosis and treatment of more than 75 of the most commonly seen pediatric infectious diseases. Includes more than 500 full-color images adjacent to concise diagnostic and treatment guidelines. Essential information on each condition is presented in the precise sequence needed in the clinical setting: Clinical manifestations, Etiology, Epidemiology, Incubation period, Diagnostic tests, Treatment

Antiprotozoal Drug Development and Delivery

Author : Alane Beatriz Vermelho
Publisher : Springer Nature
ISBN 13 : 3031068505
Total Pages : 333 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Antiprotozoal Drug Development and Delivery by : Alane Beatriz Vermelho

Download or read book Antiprotozoal Drug Development and Delivery written by Alane Beatriz Vermelho and published by Springer Nature. This book was released on 2022-06-24 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews new promising drug targets for Neglected Tropical Diseases (NTDs), with a special focus on antiprotozoal drugs against trpyanosomatids Trypanosoma cruzi and Leishmania spp. The book offers a comprehensive overview of the most recent studied targets, and it outlines classical and new treatments and delivery strategies. Expert contributors describe new methods of analysis and bio-prospecting for new compounds, and provide a critical perspective of the translational process used in the research and development of new drug candidates. The book will appeal not only to researchers, students and professionals interested in drug development to protozoan diseases, but also to medicinal chemists in general.