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Recent Discoveries On A Optimal Designs For Comparing Test Treatments With Controls
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Book Synopsis Recent Discoveries on A-Optimal Designs for Comparing Test Treatments with Controls by : A. S. Hedayat
Download or read book Recent Discoveries on A-Optimal Designs for Comparing Test Treatments with Controls written by A. S. Hedayat and published by . This book was released on 1986 with total page 23 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors introduce the problem with an example. How should we design an experiment to compare 4 test treatments with a control, using 18 experimental units? As a statistical question we will not be able to answer it unless it is asked in a more precise manner. To begin with we need to postulate a model for the response observed upon application of a treatment, test treatment or control, to an experimental unit. This paper shall consider three possible models: 1) O-way elimination of heterogeneity model in which all experimental units are homogeneous before application of treatments; 2) 1-way elimination of heterogeneity model in which experimental units can be divided into several homogeneous blocks; and 3) 2-way elimination of heterogeneity model in which the experimental units can be conceptually arranged according to rows and columns.
Book Synopsis Theory of Optimal Designs by : Kirti R. Shah
Download or read book Theory of Optimal Designs written by Kirti R. Shah and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been an enormous growth in recent years in the literature on discrete optimal designs. The optimality problems have been formulated in various models arising in the experimental designs and substantial progress has been made towards solving some of these. The subject has now reached a stage of completeness which calls for a self-contained monograph on this topic. The aim of this monograph is to present the state of the art and to focus on more recent advances in this rapidly developing area. We start with a discussion of statistical optimality criteria in Chapter One. Chapters Two and Three deal with optimal block designs. Row-column designs are dealt with in Chapter Four. In Chapter Five we deal with optimal designs with mixed effects models. Repeated measurement designs are considered in Chapter Six. Chapter Seven deals with some special situations and Weighing designs are dis cussed in Chapter Eight. We have endeavoured to include all the major developments that have taken place in the last three decades. The book should be of use to research workers in several areas including combinatorics as well as to the experimenters in diverse fields of applications. Since the details of the construction of the designs are available in excellent books, we have only pointed out the designs which have optimality proper ties. We believe, this will be adequate for the experimenters.
Book Synopsis Optimal Designs when Comparing Experimental Treatments with a Control by : Azhar Nizam
Download or read book Optimal Designs when Comparing Experimental Treatments with a Control written by Azhar Nizam and published by . This book was released on 1987 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Technical Reports Awareness Circular : TRAC. by :
Download or read book Technical Reports Awareness Circular : TRAC. written by and published by . This book was released on 1987-12 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Collection of A-Optimal Designs for Control-Test Treatment Comparisons. I. by : A. S. Hedayat
Download or read book A Collection of A-Optimal Designs for Control-Test Treatment Comparisons. I. written by A. S. Hedayat and published by . This book was released on 1983 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt: A-optimal designs for comparing v test treatments with a control in b blocks of size k each are considered. 111 such designs are given when the parameters are in the range: 2
Book Synopsis A-Optimal Block Designs for Comparing Test Treatments with a Control by : John Stufken
Download or read book A-Optimal Block Designs for Comparing Test Treatments with a Control written by John Stufken and published by . This book was released on 1986 with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document considers the problem of comparing test treatments with a control in a proper block design. The auther derives sufficient conditions for the A-optimality of both R-type and S-type designs, and demonstrates how these conditions can be used to obtain families of optimal designs. He gives an example for the construction of the desired S-type designs. A table with optimal R-type designs (3> or = k> or = 10, k> or = v> or = 30) is also given.
Book Synopsis Optimal Repeated Measurements Designs for Comparing Test Treatments with a Control by : Dibyen Majumdar
Download or read book Optimal Repeated Measurements Designs for Comparing Test Treatments with a Control written by Dibyen Majumdar and published by . This book was released on 1987 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: A-optimal and MV-optimal repeated measurements designs are given both for direct and residual treatment effects, for comparing several test treatments with a control. The model considered are basically of two types: without preperiods and the circular model. It is shown that some known balanced and strongly balanced uniform repeated measurements designs can be modified to obtain optimal designs for this problem. Some other methods of finding optimal designs are also given. Keywords: Experimental design; Problem solving.
Book Synopsis Optimal Step Type Designs for Comparing Test Treatments with a Control by : C. S. Cheng
Download or read book Optimal Step Type Designs for Comparing Test Treatments with a Control written by C. S. Cheng and published by . This book was released on 1986 with total page 26 pages. Available in PDF, EPUB and Kindle. Book excerpt: The problem of obtaining A optimal designs for comparing v test treatments with a control in b blocks of size k each is considered. A step type design is a BTIB design in which the control is replicated t times in some blocks and t + 1 times in the remaining blocks. A condition on the parameters (v, b, k) is identified for which optimal step type designs can be obtained. Families of such designs are given. Methods for searching for highly efficient designs are proposed, for situations where it is difficult to determine an A optimal design.
Book Synopsis Discussion of the Paper "optimal Designs for Comparing Treatments with Controls" by A. S. Hedayat, Mike Jacroux and Dibyen Majumdar by : Robert Eric Bechhofer
Download or read book Discussion of the Paper "optimal Designs for Comparing Treatments with Controls" by A. S. Hedayat, Mike Jacroux and Dibyen Majumdar written by Robert Eric Bechhofer and published by . This book was released on 1988 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Optimal Designs for Treatment-control Comparisons in the Presence of Two-way Heterogeneity by : W. I. Notz
Download or read book Optimal Designs for Treatment-control Comparisons in the Presence of Two-way Heterogeneity written by W. I. Notz and published by . This book was released on 1984 with total page 19 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Design of Experiments for Comparing Treatments with a Control: Tables of Optimal Allocations of Observations by : Robert E. Bechhofer
Download or read book Design of Experiments for Comparing Treatments with a Control: Tables of Optimal Allocations of Observations written by Robert E. Bechhofer and published by . This book was released on 1981 with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis AMSTAT News by : American Statistical Association
Download or read book AMSTAT News written by American Statistical Association and published by . This book was released on 2004 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Scientific and Technical Aerospace Reports by :
Download or read book Scientific and Technical Aerospace Reports written by and published by . This book was released on 1994 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Small Clinical Trials by : Institute of Medicine
Download or read book Small Clinical Trials written by Institute of Medicine and published by National Academies Press. This book was released on 2001-01-01 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.
Book Synopsis Government Reports Announcements & Index by :
Download or read book Government Reports Announcements & Index written by and published by . This book was released on 1988-02 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Optimal Group Divisible Treatment Designs for Comparing a Standard Treatment with Test Treatments by : J. Stufken
Download or read book Optimal Group Divisible Treatment Designs for Comparing a Standard Treatment with Test Treatments written by J. Stufken and published by . This book was released on 1991 with total page 23 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Principles and Practice of Clinical Research by : John I. Gallin
Download or read book Principles and Practice of Clinical Research written by John I. Gallin and published by Academic Press. This book was released on 2017-11-17 with total page 826 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles and Practice of Clinical Research, Fourth Edition has been thoroughly revised to provide a comprehensive look at both the fundamental principles and expanding practice of clinical research. New to this edition of this highly regarded reference, authors have focused on examples that broadly reflect clinical research on a global scale while including a discussion of international regulations, studies, and implications. In addition to key topics such as bioethics, clinical outcome data, cultural diversity, protocol guidelines, and “omic platforms, this edition contains new chapters devoted to electronic health records and information resources for clinical researchers, as well as the many opportunities associated with big data. Covering a vast number of topics and practical advice for both novice and advanced clinical investigators, this book is a highly relevant and essential resource for all those involved in conducting research. Features input from experts in the field dedicated to translating scientific research from bench to bedside and back Provides expanded coverage of global clinical research Contains hands-on, practical suggestions, illustrations, and examples throughout Includes new chapters on the international regulation of drugs and biologics, the emergence of the important role of comparative effectiveness research and how to identify clinical risks and manage patient safety in a clinical research setting
