Recent Concepts In Sarcoma Treatment

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Recent Concepts in Sarcoma Treatment

Author : J.R. Ryan
Publisher : Springer Science & Business Media
ISBN 13 : 940092691X
Total Pages : 348 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Recent Concepts in Sarcoma Treatment by : J.R. Ryan

Download or read book Recent Concepts in Sarcoma Treatment written by J.R. Ryan and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: There have been significant advances in the treatment of sarcomas in the past several years. Further, different clini cal treatment programs are being advocated in different areas including surgery alone, surgery with preoperative or post operative chemotherapy, surgery with different radiotherapy modalities, with each investigator espousing his own treat ment program. On the other side, there is the question of whether these treatment programs are offering better results or whether the natural history of sarcomas has changed. The International Symposium on Sarcomas was held at Innisbrook Resort, Tarpon Springs, Florida, October 8-10, 1987. This was the first international symposium to date involving all of the disciplines treating sarcomas including pathologists, orthopaedic surgeons, general surgeons, medical oncologists, pediatric oncologists, and radiation oncol ogists. The Symposium brought together a number of special ists working in the clinical field of sarcomas for a presen tation of their specific treatment programs and their results. The presentations were followed by panel discussions to stimulate educational debate as to the different forms of treatment for sarcomas and to formulate some conformity in control of disease, control of spread, and ultimate function for the patient. James R. Ryan, M.D.

Treatment of Soft Tissue Sarcomas

Author : H.M. Pinedo
Publisher : Springer Science & Business Media
ISBN 13 : 1461317576
Total Pages : 143 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Treatment of Soft Tissue Sarcomas by : H.M. Pinedo

Download or read book Treatment of Soft Tissue Sarcomas written by H.M. Pinedo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the major advances of the last decade concerning the treatment of patients with soft tissue sarcomas is that an increased number of patients are being discussed in multidisciplinary teams prior to the initial treatment. The present volume on soft tissue sarcomas in the series Cancer Treatment and Research reflects the multidisciplinary approach with a focus on recent developments. The availability of new histopathologic techniques has reduced the number of unclassified sarcomas and has furhter increased the importance of the histo pathologist in providing estimates of the prognosis of the patient as well as data for the planning of treatment strategy. Further data for this strategy will be provided by diagnostic imaging. In this field, the role of magnetic reson ance imaging has been further defined. Of utmost importance is the recent trend toward consensus in staging. The modification of the staging system of the American Joint Commission for Cancer Staging and End Results Report ing brings the possibility of a single staging system within reach in the next decade. As surgery still provides the only chance for cure, the importance of being the most sparing as possible is obvious. For this reason, radiotherapy has been applied with success. The introduction of relatively new radiation tech niques is therefore being observed with interest.

Soft Tissue Sarcomas: New Developments in the Multidisciplinary Approach to Treatment

Author : H.M. Pinedo
Publisher : Springer Science & Business Media
ISBN 13 : 1461538963
Total Pages : 181 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Soft Tissue Sarcomas: New Developments in the Multidisciplinary Approach to Treatment by : H.M. Pinedo

Download or read book Soft Tissue Sarcomas: New Developments in the Multidisciplinary Approach to Treatment written by H.M. Pinedo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative, but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfor tunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes that aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, which is revised frequently to keep the coverage up to date, and which is easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion: first, by dividing the oncology literature into specific subdivisions, such as lung can cer, genitourinary cancer, pediatric oncology, etc.; and second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diag nosis, staging, markers, all forms of treatment modalities, basic biology, and more.

Treatment of Bone and Soft Tissue Sarcomas

Author : Per-Ulf Tunn
Publisher : Springer Science & Business Media
ISBN 13 : 3540779604
Total Pages : 372 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Treatment of Bone and Soft Tissue Sarcomas by : Per-Ulf Tunn

Download or read book Treatment of Bone and Soft Tissue Sarcomas written by Per-Ulf Tunn and published by Springer Science & Business Media. This book was released on 2008-12-28 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone and soft tissue sarcomas represent only about 2% of all malignancies; however, their treatment – with the goal of curing the patient while preserving the functionality of the affected body part – can, unlike other malignancies, only be successful with therapy concepts devised by interdisciplinary teams. This volume provides an extensive up-to-date overview of the specific diagnostics and current treatment standards of these rare entities, presenting the various limb-sparing modalities for patients with bone and soft tissue sarcomas with special regard to innovative reconstructive options. The evaluation of quality of life based on validated scores and the individual methods of coping with the illness through creative artistic projects are also acknowledged and integrated in the whole concept.

Soft Tissue Sarcomas

Author : Michael E. Newman
Publisher : The Rosen Publishing Group, Inc
ISBN 13 : 1448823323
Total Pages : 64 pages
Book Rating : 4.4/5 (488 download)

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Book Synopsis Soft Tissue Sarcomas by : Michael E. Newman

Download or read book Soft Tissue Sarcomas written by Michael E. Newman and published by The Rosen Publishing Group, Inc. This book was released on 2011-01-15 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes soft tissue sarcomas, including the different types of sarcomas, diagnosis and treatment, and current medical research on the disease.

New Trends in the Treatment of Sarcoma, An issue of Surgical Clinics of North America

Author : Jeffrey M. Farma
Publisher : Elsevier Health Sciences
ISBN 13 : 032346338X
Total Pages : 329 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis New Trends in the Treatment of Sarcoma, An issue of Surgical Clinics of North America by : Jeffrey M. Farma

Download or read book New Trends in the Treatment of Sarcoma, An issue of Surgical Clinics of North America written by Jeffrey M. Farma and published by Elsevier Health Sciences. This book was released on 2016-08-24 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Surgical Clinics of North America, guest edited by Drs. Jeffrey M. Farma and Andrea Porpiglia, is devoted to Sarcoma. They have assembled expert authors to review the following topics: Epidemiology and Etiology of Sarcomas; Management of Extremity Sarcomas; Management of Retroperitoneal Sarcomas; Management of Dermatofibrosarcoma Protuberans; Management of Desmoids; Management of Truncal Sarcomas; Management of Bone Sarcomas; Management of Pediatric Sarcomas; Local Recurrence of Sarcomas; Management of Metastatic Disease; Imaging of Sarcomas; Management of Gastrointestinal Stromal Tumors; Management of Breast Sarcoma; Chemotherapy for Sarcomas; Pathology and Classification of Sarcomas; Radiation Therapy for Sarcomas; and more!

Current Advances in Osteosarcoma

Author : Eugenie S. Kleinerman, M.D.
Publisher : Springer
ISBN 13 : 9783319344591
Total Pages : 0 pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Current Advances in Osteosarcoma by : Eugenie S. Kleinerman, M.D.

Download or read book Current Advances in Osteosarcoma written by Eugenie S. Kleinerman, M.D. and published by Springer. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Advances in Osteosarcoma edited by Dr. Eugenie S. Kleinerman summarizes molecular and genetic characteristics, new therapeutic ideas, and biological characteristics that have been uncovered in the past 10 years. Osteosarcoma is an aggressive malignant neoplasm and it is also the most common histological form of bone cancer. It accounts for approximately 56% of new bone tumors, making it the most primary malignant bone tumor in children and adolescents. The lungs are the most common site of metastases and once osteosarcoma spreads to the lungs, it is very difficult to treat. To improve the outcome of this disease, the biology of osteosarcoma needs to be better understood. There are numerous investigators around the world who have made seminal discoveries about the important molecular pathways and genetic alterations that contribute to the development and metastases of osteosarcoma. Other investigators have proposed novel therapeutic strategies including some based on the molecular and genetic phenotype of the disease. Current Advances in Osteosarcoma summarizes all of these new discoveries in one singular text, which will help move the field forward.

Current Advances in Osteosarcoma

Author : Eugenie S. Kleinerman
Publisher : Springer Nature
ISBN 13 : 3030430324
Total Pages : 214 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Current Advances in Osteosarcoma by : Eugenie S. Kleinerman

Download or read book Current Advances in Osteosarcoma written by Eugenie S. Kleinerman and published by Springer Nature. This book was released on 2020-06-01 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thoroughly revised second edition complied in 2 books is an up-to-date overview of the current clinical advances in sarcoma and osteosarcoma. The new edition features detailed, in-depth discussions of microRNAs in osteosarcoma, historical perspectives of chemotherapy in the treatment of the disease, tumor targeted IL12 therapy and HER2 targeted therapy, the role of enhancer elements in regulating the prometastatic transcriptional program and more. Further, these essential volumes also includes new insights on Wnt signaling in osteosarcoma, the role of genomics, genetically modified T-cell therapy, liquid biopsy, oncolytic viruses, immunophenotyping, receptor tyrosine kinases and epigenetic-focused approaches for treatment of osteosarcoma metastases, as well as thoughts on the current standard of treatment for patients suffering from these cancers. In the years since the previous edition, there have been numerous new developments in this rapidly changing field; this new edition is both timely and urgently needed. When taken together these companion volumes, Current Clinical (Book 1) and Scientific (Book 2) Advances in Osteosarcoma, are a timely and urgently needed guide for laboratory investigators and clinical oncologists focused in sarcoma.

Current Concepts of Diagnosis and Treatment of Bone and Soft Tissue Tumors

Author : H. K. Uhthoff
Publisher : Springer Science & Business Media
ISBN 13 : 3642692109
Total Pages : 435 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Current Concepts of Diagnosis and Treatment of Bone and Soft Tissue Tumors by : H. K. Uhthoff

Download or read book Current Concepts of Diagnosis and Treatment of Bone and Soft Tissue Tumors written by H. K. Uhthoff and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past decade, the prognosis of bone and soft tissue tumors has improved considerably. This progress has not only been due to improved therapeutics and diagnostic methods but also due to a team approach now universally adopted. Comparison of results, possible today, were hampered in the past by lack of a clinically relevant staging system and definitive treatment proto cols. The complexity of the therapeutic management of bone tumors re quires a constant exposure to tumors, highly skilled diagnostic tech niques, and specialized expertise. It is therefore not surprising to learn that small and medium-sized hospitals embarking on the diagnosis and treatment of bone and soft tissue tumors are generally less success ful than better equipped major centers. This fact has already been recognized by most physicians and surgeons who now refer their patients to specialized oncologic centers. Nevertheless, they all have to know the present state of the art. This symposium was therefore mostly addressed to them. This international symposium, organized by the Division of Orthopaedic Surgery, University of Ottawa, and cosponsored by the Association des Chirurgiens Orthopedistes du Quebec, was held in Ottawa from May 12-14, 1983. Each of the 40 presentations clearly demonstrates that disregard for proper staging before initiation of treatment and omission of a clearly defined treatment protocol is definitely unacceptable in view of the knowledge we have acquired.

Sarcomas

Author : Jonathan C. Trent, MD, PhD
Publisher : Springer Publishing Company
ISBN 13 : 0826148530
Total Pages : 444 pages
Book Rating : 4.8/5 (261 download)

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Book Synopsis Sarcomas by : Jonathan C. Trent, MD, PhD

Download or read book Sarcomas written by Jonathan C. Trent, MD, PhD and published by Springer Publishing Company. This book was released on 2020-09-23 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sarcomas: Evidence-Based Diagnosisand Management is the most comprehensive clinical reference on sarcomas available to oncologists and trainees. Presenting a compilation of the current knowledge of specific soft tissue and bone sarcomas, this accessible resource on diagnosis and management is the most practical in the market. Led by the world’s foremost sarcomas experts in medical oncology, surgical oncology, radiation oncology, gynecologic oncology, orthopedic surgery, radiology, and pathology, the book addresses the general principles of each major medical discipline, provides details on each major sarcoma subtype, and presents the evidence for standard frontline, adjuvant, and novel treatment approaches such as immunotherapy, cellular therapies, and more. The book begins with general principles of diagnosis and management for each discipline in the field, covering specialties from medical oncology to radiology. Following the chapters on general principles, are chapters characterizing the most prevalent subtypes of sarcoma including their estimated incidence, common presenting symptoms, diagnostic approach, radiographic features and essential imaging, key diagnostic features, molecular characteristics, approaches to treatment, recommended follow up, the metastatic potential as well as evidence-based therapeutic approaches. Each chapter ends with a summary of caveats, clinical pearls, pitfalls, and solutions as well as a case study from the clinician’s point of view. The book ends with chapters focusing on new approaches to treatment and the development of therapeutics to combat sarcoma using immunotherapy, cellular therapy, and interventional radiology. Numerous tables and disease-based images support the text and provide key information for quick reference. Presenting detailed evidence and authoritative clinical guidance throughout, Sarcomas is a “one-stop” guide for any clinician diagnosing, treating, or managing patients suffering from these heterogenous diseases. Key Features: Provides the standards of care and evidence base for treatment of each major sarcoma subtype Covers all new treatment paradigms and FDA approvals Includes numerous quick reference tables and high-quality color images Presents over 20 practical case studies from leading clinicians in the field

Treatment of Bone and Soft Tissue Sarcomas

Author : Per-Ulf Tunn
Publisher : Springer
ISBN 13 : 9783540870616
Total Pages : 362 pages
Book Rating : 4.8/5 (76 download)

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Book Synopsis Treatment of Bone and Soft Tissue Sarcomas by : Per-Ulf Tunn

Download or read book Treatment of Bone and Soft Tissue Sarcomas written by Per-Ulf Tunn and published by Springer. This book was released on 2009-08-29 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone and soft tissue sarcomas represent only about 2% of all malignancies; however, their treatment – with the goal of curing the patient while preserving the functionality of the affected body part – can, unlike other malignancies, only be successful with therapy concepts devised by interdisciplinary teams. This volume provides an extensive up-to-date overview of the specific diagnostics and current treatment standards of these rare entities, presenting the various limb-sparing modalities for patients with bone and soft tissue sarcomas with special regard to innovative reconstructive options. The evaluation of quality of life based on validated scores and the individual methods of coping with the illness through creative artistic projects are also acknowledged and integrated in the whole concept.

Immunotherapy of Sarcoma

Author : Sandra P. D'Angelo
Publisher : Springer
ISBN 13 : 9783319935294
Total Pages : 152 pages
Book Rating : 4.9/5 (352 download)

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Book Synopsis Immunotherapy of Sarcoma by : Sandra P. D'Angelo

Download or read book Immunotherapy of Sarcoma written by Sandra P. D'Angelo and published by Springer. This book was released on 2018-10-24 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes recent progress in the development of immunotherapies for advanced sarcoma, paying special attention to the potential role of manipulations of the sarcoma tumor immune microenvironment in improving patient outcomes. Readers will find a thorough overview of the state of the art in tumor immunology and immunotherapy as they relate to sarcoma. Among the topics addressed are advances in vaccine therapy; cytokine therapies; natural killer cells; the development of adoptive T cell strategies; and the scope for use of checkpoint inhibitors in patients with sarcoma, mirroring the tremendous breakthroughs made in other malignancies. Detailed information is provided on laboratory and clinical research, with analysis of outcomes of recent trials and identification of key challenges. There is every reason to believe that more effective and less toxic therapies for metastatic sarcoma can be attained by deepening our understanding of cancer immunology and building on the advances in immunotherapy for other solid tumors. In this context, Immunotherapy of Sarcoma will be of high interest for all medical oncologists responsible for the treatment of sarcoma patients.

Diagnosis of Musculoskeletal Tumors and Tumor-like Conditions

Author : Piero Picci
Publisher : Springer Nature
ISBN 13 : 3030296768
Total Pages : 346 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Diagnosis of Musculoskeletal Tumors and Tumor-like Conditions by : Piero Picci

Download or read book Diagnosis of Musculoskeletal Tumors and Tumor-like Conditions written by Piero Picci and published by Springer Nature. This book was released on 2019-12-06 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, now in a second revised edition, casts light on the often complex diagnosis of musculoskeletal tumors and tumor-like conditions by drawing on the experience of the Rizzoli Orthopedic Institute during more than 100 years of treatment and research in the field. The different entities are described from a multidisciplinary perspective, highlighting clinical, radiological, and histological correlations. Particular emphasis is placed on differential diagnosis, which often needs to take into account nontumoral conditions. The recent identification of further significant biological and genetic features, and the impact of these discoveries on the classification of round cell tumors, vascular lesions, and spindle/pleomorphic entities in bone, is also extensively discussed. The Rizzoli case archive dates back to September 1900 and contains the original material relating to more than 29,000 bone lesions and 11,000 soft tissue lesions. It is a fabulously rich resource, and this book will be invaluable for pathologists, radiologists, and clinicians at all levels of experience.

Soft Tissue and Bone Tumours

Author : WHO Classification of Tumours Editorial Board
Publisher : WHO Classification of Tumours
ISBN 13 : 9789283245025
Total Pages : 0 pages
Book Rating : 4.2/5 (45 download)

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Book Synopsis Soft Tissue and Bone Tumours by : WHO Classification of Tumours Editorial Board

Download or read book Soft Tissue and Bone Tumours written by WHO Classification of Tumours Editorial Board and published by WHO Classification of Tumours. This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: PLEASE NOTE: Text has been accidentally deleted from page 54 of this book. Please refer to the corrigenda (PDF file) posted on the Stylus Publishing web site or email [email protected] for an updated, printable page. ****When not purchasing directly from the official sales agents of the WHO, especially at online bookshops, please note that there have been issues with counterfeited copies. Buy only from known sellers and if there are quality issues, please contact the seller for a refund.***** Soft Tissue and Bone Tumours is the third volume in the 5th edition of the WHO series on the classification of human tumours. This series (also known as the WHO Blue Books) is regarded as the gold standard for the diagnosis of tumours and comprises a unique synthesis of histopathological diagnosis with digital and molecular pathology. These authoritative and concise reference books provide indispensable international standards for anyone involved in the care of patients with cancer or in cancer research, underpinning individual patient treatment as well as research into all aspects of cancer causation, prevention, therapy, and education. This volume will be of particular interest to pathologists, oncologists, surgeons, and epidemiologists who manage or research soft tissue and bone tumours. Sections are included on all recognized neoplasms of the soft tissue and bone, as well as on genetic tumour syndromes affecting these sites. Since the previous edition, there have been changes based on recent molecular and genetic information, with impact on clinical practice.

Management of Soft Tissue Sarcoma

Author : Murray F. Brennan
Publisher : Springer
ISBN 13 : 3319419064
Total Pages : 398 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Management of Soft Tissue Sarcoma by : Murray F. Brennan

Download or read book Management of Soft Tissue Sarcoma written by Murray F. Brennan and published by Springer. This book was released on 2016-12-15 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Management of Soft Tissue Sarcoma, 2nd Edition provides the most comprehensive analysis of demographics and natural history currently available for these lesions, based on the authors’ experience with over 10,000 patients. Sections regarding radiation therapy not found in the previous text have been expanded, as have updates on molecular characteristics of sarcomas and chemotherapy studies published since the prior edition. Clinical and molecular diagnoses are addressed, and tumor histopathology is employed as the basis of treatment recommendations including surgery, radiation and systemic therapy. This is the first book to provide specific chemotherapy opinions for every sarcoma subtype. Written by four world-renowned experts, this book gives a practical, up-to-date approach to managing the many subtypes of adult soft tissue sarcoma. Reviews from the first edition: “This is an impressive book. Written by a surgeon, a pathologist and an oncologist, the book draws heavily on the Memorial Sloan-Kettering Cancer Center soft tissue sarcoma (STS) database. ... it is a book that should be in the library of any sarcoma unit and will appeal to the sub-specialist in Orthopaedic Oncology.” (Robert U. Ashford, European Journal of Orthopaedic Surgery & Traumatology, Vol. 24, 2014) “The book is laid out in 27 chapters, with an impressive inclusion of a wide array of sarcoma histology. One of the real strengths of the book is the quality and number of images, figures, tables, and graphs. ... The overall outline of the text is well done. ... This book is a unique and important addition to the sarcoma literature. ... this edtion should find itself on every medical oncologist’s bookshelf ... .” (Larry C. Daugherty and Sanjay P. Bagaria, Journal of Radiation Oncology, Vol. 3, 2014)

Sarcoma

Author : Eric J. Butler
Publisher : Nova Biomedical Books
ISBN 13 : 9781621004080
Total Pages : 193 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis Sarcoma by : Eric J. Butler

Download or read book Sarcoma written by Eric J. Butler and published by Nova Biomedical Books. This book was released on 2012-03-01 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sarcomas are a group of rare malignant tumors that constitute less than 1% of all cancers, arising from the mesenchymal system. About 80% originate in soft tissue (muscle, nerves, joints, blood vessels, deep skin tissues, and fat), while the remainder originate in bone and cartilage. In this book, the authors present topical research on the symptoms, causes and treatments of sarcoma. Some of the topics discussed include clinical-histopathologic diagnosis of the kaposi's sarcoma; ovarian sarcoma in mice; advances in chondrosarcoma treatment; the potential of suicide plus immune gene therapy for treating osteosarcoma; new concepts of limb salvage surgery in musculoskeletal sarcomas with acridine orange therapy; the role of surgery in children with head and neck rhabdomyosarcoma and gastrointestinal kaposi's sarcoma. (Imprint: Nova biomedical)

Surgery for Bone and Soft-tissue Tumors

Author : Michael Allan Simon
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780397513963
Total Pages : 756 pages
Book Rating : 4.5/5 (139 download)

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Book Synopsis Surgery for Bone and Soft-tissue Tumors by : Michael Allan Simon

Download or read book Surgery for Bone and Soft-tissue Tumors written by Michael Allan Simon and published by Lippincott Williams & Wilkins. This book was released on 1998 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a comprehensive guide to the diagnosis and treatment of benign and malignant tumors of the bone and soft tissues. Coverage includes: general issues in diagnosis, staging, surgery, radiation therapy, chemotherapy, and the psychological aspects of patient management. Focus is placed on benign bone tumors, malignant bone tumors, soft-tissue tumors, and carcinoma metastatic to bone. The sections on malignant bone tumors and carcinoma metastatic to bone include detailed guidelines for surgical treatment in each anatomic site. Special features include: considerations for management of malignant bone tumors in growing children; and discussions on the biology and complications of prosthetic and allograft reconstruction.